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Publications in peer-reviewed journals, Reviews, Book chapters, Comments etc.


Members of the Sodeik Team are highlighted in bold.


P Ashford (joint first author), A Hernandez (joint first author), TM Greco, A Buch, B Sodeik, I Cristea, K Grünewald (corresponding author), A Shepherd (corresponding author) & M Topf (corresponding author, 2016). HVint: A strategy for identifying novel protein‐protein interactions in herpes simplex virus type 1. Molecular Cell Proteomics, in revision.



R Budida*, MV Stankov*, K Döhner, KA Tappe, A Buch, D Panayotova‐Dimitrova, B Sodeik & GMN Behrens (2016). HSV‐1 interference with dendritic cells’ autophagy determines their MHC class I capacity to present viral antigens and to stimulate T cell proliferation. Autophagy, in revision.



B Sodeik, M Messerle & TF Schulz (2016). Kapitel 71 – Herpesviren. In: Medizinische Mikrobiologie und Infektiologie, Springer‐Verlag Heidelberg, 8. Auflage, im Druck.



L Ivanova, A Buch, K Döhner, A Pohlmann, A Binz, M Sandbaumhüter, U Prank, R Bauerfeind (corresponding author) & B Sodeik (corresponding author, 2016). Conserved tryptophan motifs in the large tegument protein pUL36 are required for efficient secondary envelopment of Herpes Simplex Virus. Journal of Virology, accepted.



EM Borst*, R Bauerfeind, A Binz, B Sodeik, TM Stephan, K Wagner, L Steinbrück, T Lenac‐Roviš, S Jonjić, M Messerle* (2016). The essential human cytomegalovirus proteins pUL77 and pUL93 are structural components necessary for viral genome encapsidation. Journal of Virology, accepted.



G Zhang, B Chan, N Smarina, B Abere, M Weidner‐Glunde, A Buch, A Pich, MM Brinkmann & TF Schulz (2016). Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Proceedings of the National Academy of Sciences USA, doi:10.1073/pnas.1516812113.



JB Bosse, IB Hogue, M Feric, SY Thiberge, B Sodeik, CP Brangwynne & LW Enquist (2015). Remodeling nuclear architecture to allow efficient transport of herpesvirus capsids by diffusion. Proceedings of the National Academy of Sciences USA, 112:E5725‐33.



C Funk (joint first author), M Ott (joint first author), V Raschbichler (joint first author), CH Nagel, A Binz, B Sodeik, R Bauerfeind & S Bailer (2015). A Herpes simplex virus type 1 pUL31 escorts mature nucleocapsids to sites of nuclear egress, a process coordinated by its N‐terminal domain. PLoS Pathogens, 11(6): e1004957. doi:10.1371/journal.ppat.1004957.



IVA Pereira (joint first author), B Buchmann (joint first author), L Sandmann, K Sprinzl, V Schlaphoff , K Döhner, F Vondran, C Sarrazin, MP Manns, CPMS de Oliveira, B Sodeik, S Ciesek (corresponding author) & T von Hahn (corresponding author, 2015). Primary biliary acids inhibit hepatitis D virus (HDV) Entry into Human Hepatoma cells expressing the sodium‐taurocholate transporting polypeptide (NTCP). PLoS ONE 10(2):e0117152. doi: 10.1371/journal.pone.0117152.



A Krawczyk (corresponding), M Dirks, M Hennig, A Buch, U Dittmer, B Giebel, L Bagnewski, M Busch, A Goergens, K Schneweis, AM Eis‐Hübinger, B Sodeik, A Heiligenhaus, M Roggendorf & D Bauer (2015). Prevention of Herpes Simplex Virus induced Stromal Keratitis by a glycoprotein B‐specific monoclonal antibody. PLoS ONE, 10(1):e0116800. doi:10.1371/journal.pone.0116800.



F Anderson (joint first author), A Savulescu (joint first author), K Rudolph, J Schipke, I Cohen, I Ibiricu, A Rotem, K Grünewald, B Sodeik (corresponding author) & A Harel (corresponding author, 2014). Specific targeting of Herpes Simplex Virus Capsids to Nuclear Pores in a cell‐free nuclear reconstitution system. Traffic, 15:1266‐1281. Cover Image.;jsessionid=CF3295E1BFA 0BA143CA22091F1B2B523.f01t04



D Devadas, T Koithan, R Diestel, U Prank, B Sodeik (corresponding author) & K Döhner (corresponding author, 2014). Herpes Simplex Virus Internalization into Epithelial Cells requires Na+/H+ Exchangers and p‐21‐activated Kinases but neither Clathrin‐ nor Caveolin‐mediated Endocytosis. Journal of Virology, 88:13378‐13395. DOI: 10.1128/JVI.03631‐13.



M Schomaker, D Heinemann, S Kalies, S Willenbrock, HM Escobar, A Buch, B Sodeik, T Ripken, & H Meyer (2014). Mechanistic investigations and molecular medicine applications of gold nanoparticle mediated (GNOME) laser transfection. Proc. S IE 8972, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial
Applications XIV
, 897207; doi:10.1117/12.2039379 (Conference Proceedings).



BJ Kelly, R Bauerfeind, A Binz, B Sodeik, AS Laimbacher, C Fraefel & RJ Diefenba h (2014). The interaction of the HSV‐1 tegument proteins pUL36 and pUL37 is essential for secondary envelopment during viral egress. Virology 454‐455:67‐77.



K Radtke, F Anderson & B Sodeik (2014). A precipitation‐based assay to analyze interactions of viral particles with cytosolic host factors. Method Mol Biol, 1144:191‐ 208.‐1‐4939‐0428‐0_13



CH Nagel, A Pohlmann & B Sodeik (2014). Construction and characterization of BACs containing Herpes Simplex Virus full‐length genomes Methods Mol Biol, 1144:43‐62.‐1‐4939‐0428‐0_4



AE Lin, TM Greco, K Döhner, B Sodeik & I Cristea (2013). A Proteomic Perspective of Inbuilt Viral Protein Regulation: pUL46 Viral Tegument Protein is Targeted for Degradation by the Viral ICP0 Protein during HSV‐1 Infection. Molecular Cell Proteomics 12:3237‐3252.



G Schudt, L Kolesnikova, O Dolnik, B Sodeik & S Becker (2013). Live‐cell imaging of Marburg virus‐infected cells uncovers actin‐dependent transport of nucleocapsids over long distances. Proceedings of the National Academy of Sciences USA, 110:14402‐407.



M Nygardas (corresponding author), H Paavilainen, N Müther, CH Nagel, R Matias, B Sodeik & V Hukkanen (correspondi g author, 2013). A Herpes Simplex Virus‐Derived Replicative Vector Expressing LIF Limits Experimental Demyelinating Disease and Modulates Autoimmunity. PLOS ONE 8(5): e64200.



M Sandbaumhüter, K Döhner, J Schipke, A Binz, A Pohlmann, B Sodeik (corresponding author) & R Bauerfeind (corresponding author, 2013). Cytosolic Herpes Simplex Virus Capsids not only require binding inner tegument protein pUL36 but also pUL37 for active transport prior to secondary envelopment. Cellular Microbiology, 15:248‐69. doi: 10.1111/cmi.12075.



EM Borst, J Kleine‐Albers, I Gabaev, M Babic, K Wagner, A Binz, I Degenhardt, M Kalesse, S Jonjic, R Bauerfeind, M Messerle (2013). The human cytomegalovirus UL51 protein is essential for viral genome cleavage‐packaging and interacts with the terminase subunits pUL56 and pUL89. Journal of Virology 87:248‐269.



CH Nagel (joint first author), K Döhner (joint first author), A Binz, R Bauerfeind, B Sodeik (2012). Improper Tagging of the Non‐Essential Small Capsid Protein VP26 Impairs Nuclear Capsid Egress of Herpes Simplex Virus. PLOS ONE 7(8): e644177.



MV Stankov, D Panayotova-Dimitrova, M Leverkus, FW Vondran, R Bauerfeind, A Binz, GMN Behrens, (2012). Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation. AIDS 26:1995-2006.



B Snijder, R Sacher, P Rämö, P Liberali, K Mench, N Wolfrum, L Burleigh, CC Scott, MH Verjeije, J Mercer, S Moese, T Heger, K Theusner, A Jurgeit, D Lamparter, G Balistreri, M Schelhaas, CAM De Haan, V Marjomäki, T Hyypiä, PJM Rottier, B Sodeik, M Marsh, J Gruenberg, A Amara, U Greber, A Helenius & L Pelkmans (2012). Single-cell analysis of population context advances RNAi screening at multiple levels. Molecular Systems Biology, 8:859; doi:10.1038/msb.2012.9.



B Sodeik, M Messerle & TF Schulz (2012). Kapitel 71 – Herpesviren. In: Medizinische Mikrobiologie und Infektiologie, Springer-Verlag Heidelberg, 7. Auflage, Seiten 540 -561.

   Text book chapter.


J Schipke, A Pohlmann, R Diestel, A Binz, K Rudolph, CH Nagel, R Bauerfeind & B Sodeik (2012). The C-terminus of the large Tegument protein pUL36 contains multiple capsid binding sites that function differently during assembly and cell entry of Herpes Simplex Virus. Journal of Virology, 86:3682-3700.



C Voelkel, M Galla, PN Dannhauser, T Maetzig, B Sodeik, A Schambach (corresponding) & C Baum (corresponding; 2012). Pseudotype-indendent nonspecific uptake of gammaretroviral and lentiviral particles in human cells. Human Gene Therapy, 23:274-286.



I Ibiricu, JT Huiskonen, K Döhner, F Bradke, B Sodeik & K Grünewald (2011). Cryo Electron Tomography of Herpes Simplex Virus during Axonal Transport and Secondary Envelopment in Primary Neurons. PLoS Pathogens 7(12): e1002406.



K Rode, K Döhner, A Binz, M Glass, T Strive, R Bauerfeind & B Sodeik (2011). Uncoupling uncoating of Herpes Simplex Virus genomes from their nuclear import and gene expression. Cover Image and Spotlight feature of Journal of Virology, 85:4271-4283.



B Sodeik & C Krause (2010). HSV capsids bind to host microtubule motors via inner tegument proteins. rebirth – news 3.2010.

Newsletter of the
DFG Excellence Cluster REBIRTH


K Radtke, D Kieneke, A Wolfstein, K Michael, W Steffen, T Scholz, A Karger & B Sodeik (2010). Plus- and minus-end directed microtubule motors bind simultaneously to Herpes Simplex Virus capsids using different inner tegument structures. PLoS Pathog 6(7): e1000991.



J Zhang, CH Nagel, B Sodeik & R Lippe (2009). Early, active and specific localization of HSV1 gM to nuclear membranes. Journal of Virology, 83:12984-12997.



WH Roos (joint first author), K Radtke (joint first author), E Kniesmeijer, H Geertsema, B Sodeik (corresponding author) & G Wuite (corresponding author) (2009). Scaffold expulsion and genome packaging trigger stabilization of Herpes Simplex Virus capsids. Proceedings of the National Academy of Sciences USA 106:9673-9678.



C Jung, N Ruthardt, R Lewis, J Michaelis, B Sodeik, F Nolde, K Peneva, K Müllen & C Bräuchle (2009). Photophysics of new water-soluble terrylenediimide derivatives and applications in biology. ChemPhysChem, 10:180-190.



A Jirmo, CH Nagel, C Bohnen, B Sodeik & GMN Behrens (2009). Contribution of direct and cross-presentation to CTL immunity against herpes simplex virus 1. Journal of Immunology, 182:283-292.



U Maurer, B Sodeik & K Grünewald (2008). Native 3D intermediates of membrane fusion in herpes simplex virus 1 entry. Proceedings of the National Academy of Sciences USA 105:10559-64. (Editors’ choice: Science 2008:321, page 892; Faculty of 1000 Biology




CH Nagel, K Döhner, M Fathollahy, T Strive, E Borst, M Messerle & B Sodeik (2008). Nuclear egress and envelopment of herpes simplex virus capsids analyzed with dual-color fluorescence HSV1(17+). Journal of Virology 82:3109-24.



E Borst, K Wagner, A Binz, B Sodeik & M Messerle (2008). The essential human cytomegalovirus gene UL25 is required for cleavage-packaging of the viral genome. Journal of Virology 82:2065-78.



B Sodeik (2007). The cell entry of herpes simplex virus. Zellbiologie aktuell 33:10-13.

Newsletter of the
Gesellschaft für Zellbiologie


K Döhner, K Radtke, S Schmidt & B Sodeik (2006). The eclipse phase of herpes simplex virus type 1 infection: Efficient dynein-mediated nuclear capsid targeting without the small capsid protein VP26. Journal of Virology 80:8211-24.




I Köllner, B Sodeik, S Schreek, H Heyn, N von Neuhoff, M Germeshausen, C Zeidler, M Krüger, B Schlegelberger, K Welte & C Beger (2006). Mutations in neutrophil elastase causing congenital neutropenia lead to cytoplasmic protein accumulation and induction of the unfolded protein response. Blood 108:493-500.



K Radtke, K Döhner & B Sodeik (2006). Viral interactions with the cytoskeleton: a hitchhiker's guide to the cell. Cellular Microbiology 8:387-400 (invited review).



A Wolfstein, CH Nagel, K Radtke, K Döhner, V Allan & B Sodeik (2006). The inner tegument promotes herpes simplex virus capsid motility along microtubules in vitro. Traffic 7:227-237.



K Döhner, CH Nagel & B Sodeik (2005). Viral stop-and-go along microtubules - Taking a ride with dynein and kinesins. Trends in Microbiology 13:320-327 (invited review).



K Döhner & B Sodeik (2005). The role of the host cytoskeleton for viral replication. Current Topics in Microbiology and Immunology 285:67-108 (invited review).



B Sodeik, B Schramm, M Suomalainen & J Krijnse-Locker (2005). Meeting report: EMBO Workshop - Cell Biology of Virus Infection. Traffic 6:351-356.

  Meeting Report.


M Hass, M Siegert, A Schürmann, B Sodeik & H Wolfes (2004). The c-Myb protein interacts with Rcd-1, a component of the CCR4 transcription mediator complex. Biochemistry 25:8152-59.



S Marozin, U Prank & B Sodeik (2004). Herpes simplex virus type 1 infection of polarized epithelial cells requires microtubules and access to receptors present at cell-cell contact sites. Cover Image of Journal of General Virology 85:775-786.



B Sodeik & M Kann (2003). From the entry to the progeny virus - Workshop des Arbeitskreises ZELLBIOLOGIE in der Gesellschaft für Virologie. Zellbiologie aktuell 29:27-28.

  Meeting Report. Newsletter of the Gesellschaft für Zellbiologie


B Sodeik (2002). Unchain my heart, baby let me go - the entry and intracellular transport of HIV. Journal of Cell Biology 159:393-395 (invited comment).



B Sodeik & J Krijnse-Locker (2002). Assembly of vaccinia virus revisited - Double membrane acquisition from a host organelle? Trends in Microbiology 10:15-24 (invited review).



H Mabit, MY Nakano, U Prank, B Saam, K Döhner, B Sodeik & U Greber (2002). Intact microtubules support adenovirus and herpes simplex virus infection. Journal of Virology 76:9962-9971.



J Krijnse-Locker, B Sodeik & M Suomalainen (2002). Meeting report on the EMBO Workshop - The Cell Biology of Virus Infection. Traffic 3:233-235.

  Meeting Report.


K Döhner, A Wolfstein, U Prank, C Echeverri, D Dujardin, R Vallee, & B Sodeik (2002). Function of dynein and dynactin in herpes simplex virus capsid transport. Molecular Biology of the Cell 13:2795-2809.



A Wolfstein & B Sodeik (2001). Capsid motility of herpes simplex virus type 1 along microtubles in vitro. Trends in Cell Biology, CD - GFP in Motion 2 - Live Fluorescence Imaging using Green fluorescent protein; compiled by B Ludin & A Matus (invited contribution on live cell imaging).



B Sodeik (2001). Die Zellbiologie komplexer DNA-Viren: die Reifung des Vaccinia Virus und der Zelleintirtt von Herpes-Simplex-Virus. Medizinische Hochschule Hannover, Germany. Habilitationsschrift. OCLC’s Experimental Thesis Catalog (United States).



PM Ojala (corresponding first author), B Sodeik, MW Ebersold, U Kutay & A Helenius (2000). Herpes simplex virus 1 capsid binding to nuclei and genome uncoating at the nuclear pore complex in vitro. Molecular & Cellular Biology 20:4922-4931 (cover image).



B Sodeik (2000). Mechanisms of viral transport in the cytoplasm. Trends in Microbiology 8:465-472 (invited review; cover image).



M Kann (corresponding first author), B Sodeik, A Valchou, WH Gerlich & A Helenius (1999). Phosphorylation-dependent binding of hepatitis B core particles to the nuclear pore complex.

Journal of Cell Biology 145:45-55



E Izaurralde, M Kann, N Pante, B Sodeik & T Hohn (1999). EMBO workshop report. Viruses, microorganisms and scientists meet the nuclear pore. EMBO Journal 18:289-296.

  Meeting Report.


A Alconada, U Bauer, B Sodeik & B Hoflack (1999). Intracellular traffic of herpes simplex virus glycoprotein gE: Characterization of the sorting signals required for its trans-Golgi network localization. Journal of Virology 73:377-387.



M Ericsson, B Sodeik, J Krijnse-Locker & G Griffiths (1997). Reconstitution of vaccinia virus assembly in vitro after release from the rifampicin block. Virology 235:218-227.



B Sodeik (corresponding first author), MW Ebersold & A Helenius (1997). Microtubule mediated transport of incoming herpes simplex virus I capsids to the nucleus. Journal of Cell Biology 136:1007-1021.



S Cudmore, R Blasco, R Vincentelli, M Esteban, B Sodeik, G Griffiths & J Krijnse-Locker (1996). A vaccinia virus core protein, p39, is membrane associated. Journal of Virology 70:6909-6921.



B Sodeik, S Cudmore, M Ericsson, M Esteban, EG Niles & G Griffiths (1995). Assembly of vaccinia virus: Incorporation of two membrane proteins into the intracellular mature virus. Journal of Virology 69:3560-3574.



B Sodeik, G Griffiths, M Ericsson, B Moss & RW Doms (1994). Assembly of vaccinia virus: Effects of rifampicin on the intracellular distribution of viral protein p65. Journal of Virology 68:1103-1114.



M Schmelz, B Sodeik, M Ericsson, EJ Wolffe, H Shida, G Hiller & G Griffiths (1994). Assembly of vaccinia virus: The second wrapping cisterna is derived from the trans-Golgi-network. Journal of Virology 68:130-147.



B Sodeik, RW Doms, M Ericsson, G Hiller, CE Machamer, W van' t Hof, G van Meer, B Moss & G Griffiths (1993). Assembly of vaccinia virus: Role of the intermediate compartment between the endoplasmic reticulum and the Golgi Stack. Journal of Cell Biology 121:521-541.



B Sodeik (1992). Das Assembly des Vaccinia-Virus. Dissertation an der Ruprecht-Karl-Universität Heidelberg. PhD at the European Molecular Biology Laboratory, Heidelberg, Germany. OCLC’s Experimental Thesis Catalog (United States).



G Griffiths & B Sodeik (1992). The biogenesis of vaccinia virus. In: Dynamics of Membrane Assembly. Ed. JAF op den Kamp, NATO ASI Series. 63:365-374, Springer-Verlag, Berlin.



B Sodeik & G Griffiths (1991). The role of the intermediate compartment between the
rough ER and Golgi in the biogenesis of vaccinia virus. Micron and Microscopia Acta. 22:87.



JD Loike, B Sodeik, L Cao, S Leucona, JI Weitz, PA Detmers, SD Wright & SC Silverstein (1991). CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the Aa chain of fibrinogen. Proceedings of the National Academy of Sciences USA 88:1044-1048.



B Sodeik, K Brix & W Stockem (1989). Sequestration of microinjected molecular probes from the cytoplasm of Amoeba proteus. European Journal of Protistology 25:75-84.



B Sodeik (1988). Licht- und elektronenmikroskopische Untersuchungen zur Bildung von Autophagosomen in Amoeba proteus nach Mikroinjektion markierter Proteine. Diplomarbeit am Institut für Zellbiologie der Rheinische-Friedrich-Wilhelm-Universität Bonn, Germany.

   MSc Thesis (Diplomarbeit)