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Veröffentlichungen 2011


Al-Omari M, Korenbaum E, Ballmaier M, Lehmann U, Jonigk D, Manstein DJ, Welte T, Mahadeva R, Janciauskiene S:

Acute phase protein, α1-antitrypsin, inhibits neutrophil calpain I and induces random migration.

Mol Med 2011; 17(9-10): 865-74


Agustian PA, Schiffer M, Gwinner W, Schäfer I, Theophile K, Modde F, Bockmeyer CL, Traeder J, Lehmann U, Groβhennig A, Kreipe HH, Bröcker V, Becker JU:

Diminished Met Signaling in Podocytes Contributes to the Development of Podocytopenia in Transplant Glomerulopathy.

Am J Pathol 2011; 178(5): 2007-2019


Bacher U, Haferlach T, Schnittger S, Kreipe H, Kröger N:

Recent advances in diagnosis, molecular pathology and therapy of chronic myelomonocytic leukaemia.

Br J Haematol 2011; 153(2): 149-67


Bergmann C, von Bothmer J, Ortiz Brüchle N, Venghaus A, Frank V, Fehrenbach H, Hampel T, Pape L, Buske A, Jonsson J, Sarioglu N, Santos A, Ferreira JC, Becker JU, Cremer R, Hoefele J, Benz MR, Weber LT, Buettner R, Zerres K:

Mutations in multiple PKD genes may explain early and severe polycystic kidney disease.

J Am Soc Nephrol 2011; 22(11): 2047-56


Beutel G, Wiesner O, Eder M, Hafer C, Schneider AS, Kielstein JT, Kuehn C, Heim A, Ganzenmueller T,  Kreipe H, Haverich A, Tecklenburg A, Ganser A, Welte T, Hoeper MM: 

Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection.

Critical Care 2011; 15(2): R80


Bockmeyer CL, Christgen M, Müller M, Fischer S, Ahrens P, Länger F, Kreipe H, Lehmann U:

MicroRNA profiles of healthy basal and luminal mammary epithelial cells are distinct and reflected in different breast cancer subtypes.

Breast Cancer Res Treat 2011; 130(3): 735-45


Bockmeyer CL, Forstmeier V, Modde F, Lovric S, Claus RA, Schiffer M, Agustian PA, Grothusen C, Grote K, Birschmann I, Theophile K, Kreipe HH, Bröcker V, Becker JU:

ADAMTS13--marker of contractile phenotype of arterial smooth muscle cells lost in benign nephrosclerosis.

Nephrol Dial Transplant 2011; 26(6): 1871-81


Bockmeyer CL, Reuken PA, Simon TP, Budde U, Lösche W, Bauer M, Birschmann I, Becker JU, Marx G, Claus RA:

ADAMTS13 activity is decreased in a septic porcine model. Significance for glomerular thrombus deposition.

Thromb Haemost 2011; 105(1): 145-53


Boozari B, Soudah B, Rifai K, Schneidewind S, Vogel A, Hecker H, Hahn A, Schlue J, Dietrich CF, Bahr MJ, Kubicka S, Manns MP, Gebel M:

Grading of hypervascular hepatocellular carcinoma using late phase of contrast enhanced sonography-A prospective study.

Dig Liver Dis 2011; 43(6): 484-90


Bröcker V, Schwarz A, Becker JU:

[BK virus nephropathy after kidney transplantation.]

Pathologe 2011; 32(5): 399-405 [German]


Choritz H, Büsche G, Kreipe H; Study Group HER2 Monitor:

Quality assessment of HER2 testing by monitoring of positivity rates.

Virchows Arch 2011; 459(3): 283-9


Eggers H, Waalkes S, von Klot C, Tränkenschuh W, Merseburger AS, Herrmann TR:

[Ewing`s sarcoma of the kidneys with simultaneous seminoma.]

Urologe A 2011; 50(2): 205-7 [German] 


Focken T, Steinemann D, Skawran B, Hofmann W, Ahrens P, Arnold N, Kroll P, Kreipe H, Schlegelberger B, Gadzicki D:

Human BRCA1-associated breast cancer: no increase in numerical chromosomal instability compared to sporadic tumors.

Cytogenet Genome Res 2011; 135(2): 84-92


Gonnert FA, Recknagel P, Seidel M, Jbeily N, Dahlke K, Bockmeyer CL, Winning J, Lösche W, Claus RA, Bauer M:

Characteristics of clinical sepsis reflected in a reliable and reproducible rodent sepsis model.

J Surg Res 2011; 170(1): e123-34


Göhring G, Giagounidis A, Busche G, Hofmann W, Kreipe HH, Fenaux P, Hellstrom-Lindberg E, Schlegelberger B:

Cytogenetic follow-up by karyotyping and fluorescence in situ hybridization: implications for monitoring patients with myelodysplastic syndrome and deletion 5q treated with lenalidomide.

Haematologica 2011; 96(2): 319-22


Gutenberg A, Brandis A, Hong B, Gunawan B, Enders C, Schaefer IM, Burger R, Ostertag H, Gaab M, Krauss JK, Füzesi L:

Common Molecular Cytogentic Pathway in Papillary Tumors of the Pineal Region (PTPR).

Brain Pathol 2011; 21(6): 672-7


Habicht A, Bröker V, Blume C, Lorenzen J, Schiffer M, Richter N, Klempnauer J, Haller H, Lehner F, Schwarz A:

Increase of infectious complications in ABO-incompatible kidney transplant recipients--a single centre experience.

Nephrol Dial Transplant 2011; 26(12): 4124-31


Hans K:

New Clues to Breast Cancer Heterogeneity.

Breast Care (Basel) 2011; 6(4): 256


Heckl D, Wicke DC, Brugman MH, Meyer J, Schambach A, Büsche G, Ballmaier M, Baum C, Modlich U:

Lentiviral gene transfer regenerates hematopoietic stem cells in a mouse model for Mpl-deficient aplastic anemia.

Blood 2011; 117(14): 3737-47


Hermann EJ, Hong B, Brandis A, Krauss JK:

Progressive osteolytic calvarial lesions in children after minor head injury.

Pediatr Neurosurg 2011; 47(2): 133-7


Heyn H, Engelmann M, Schreek S, Ahrens P, Lehmann U, Kreipe H, Schlegelberger B, Beger C:

MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development.

Int J Cancer 2011; 129(12): 2797-806


Hong B, Nakamura M, Brandis A, Becker H, Krauss JK:

Spinal metastasis of papillary tumor of the pineal region.

Clin Neurol Neurosurg 2011; 113(3): 235-8


Hussein K, Büsche G, Muth M, Göhring G, Kreipe H, Bock O:

Expression of myelopoiesis-associated microRNA in bone marrow cells of atypical chronic myeloid leukaemia and chronic myelomonocytic leukaemia.

Ann Hematol 2011; 90(3): 307-13


Hussein K, Horny HP, Büsche G, Görner M, Göhring G, Kreipe H, Bock O:

Systemic mastocytosis (SM) with associated BCR-ABL-positive myelogenous leukaemia (SM-AHNMD): evidence that mast cells do not belong to the leukemic clone.

Leukemia 2011; 25(6): 1050-3


Hussein K, Maecker-Kolhoff B, Klein C, Kreipe H:

[Transplant-associated lymphoproliferation.]

Pathologe 2011; 32(2): 152-8 [German]


Janciauskiene S, Ferrarotti I, Laenger F, Jonigk D, Luisetti M:

Clinical utility gene card for: α-1-antitrypsin deficiency.

Eur J Hum Genet 2011; 19(5): doi:10.1038/ejhg.2010.246


Jonigk D, Golpon H, Bockmeyer CL, Maegel L, Hoeper MM, Gottlieb J, Nickel N, Hussein K, Maus U, Lehmann U, Janciauskiene S, Welte T, Haverich A, Rische J, Kreipe H, Laenger F.

Plexiform lesions in pulmonary arterial hypertension composition, architecture, and microenvironment.

Am J Pathol 2011; 179(1): 167-79


Jonigk D, Merk M, Hussein K, Maegel L, Theophile K, Muth M, Lehmann U, Bockmeyer CL, Mengel M, Gottlieb J, Welte T, Haverich A, Golpon H, Kreipe H, Laenger F:

Obliterative airway remodeling: molecular evidence for shared pathways in transplanted and native lungs.

Am J Pathol 2011; 178(2): 599-608


Kaufmann M, Pusztai L, Biedenkopf Expert Panel Members:

Use of Standard Markers and Incorporation of Molecular Markers Into Breast Cancer Therapy: Consensus Recommendations From an International Expert Panel.

Cancer 2011; 117(8): 1575-82 [Review]


Khaladj N, Peterss S, Pichlmaier M, Shrestha M, von Wasielewski R, Hoy L, Haverich A, Hagl C:

The impact of deep and moderate body temperatures on end-organ function during hypothermic circulation arrest.

Eur J Cardiothorac Surg 2011; 40(6): 1492-9


Kilic N, Feldhaus S, Kilic E, Tennstedt P, Wicklein D, Wasielewski R, Viebahn C, Kreipe H, Schumacher U:

Brachyury expression predicts poor prognosis at early stages of colorectal cancer.

Eur J Cancer 2011; 47(7): 1080-5


Körner S, Raab P, Brandis A, Weissenborn K:

Spontaneous regression of an intracerebral lymphoma (ghost tumor) in a liver-engrafted patient.

Neurologist 2011; 17(4): 218-21


Kranz B, Kelsch R, Kuwertz-Bröking E, Bröcker V, Wolters HH, Konrad M:

Acute antibody-mediated rejection in paediatric renal transplant recipients.

Pediatr Nephrol 2011; 26(7): 1149-56 


Kreipe HH:

[Precursors of acute leukemia: myelodysplastic syndromes and myeloproliferative neoplasms.]

Pathologe 2011; 32 Suppl 2: 271-6 [German]


Kreipe HH:

[Pathology of infectious diseases. Not a trivial topic.]

Pathologe 2011; 32(5): 360-1 [German]


Kreipe HH:

[Receptor detection in breast cancer. A decade of quality assurance trials in German-speaking pathology.]

Pathologe 2011 ; 32(5): 357-9 [German]


Kümpers P, Gueler F, David S, Van Slyke P, Dumont DJ, Park JK, Bockmeyer CL, Parikh SM, Pavenstädt H, Haller H, Sushakova N:

The synthetic Tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis.

Crit Care 2011; 15(5): R261


Länger F, Puls F, Buchholz S, Loddenkemper C, Ganser A, Kreipe H:

[Histopathology of graft-versus-host disease.]

Pathologe 2011; 32(2): 144-51 [German]


Länger F, Kreipe HH:

[Immunodeficiency and immunocomprised patients. Opportunistic infection of the lungs.]

Pathologe 2011; 32(5): 411-7 [German]


Lorenzen JM, Krauter J, Länger F, Haller H, Gwinner W:

Necrotizing fasciitis and acute kidney injury in a patient with acute myelogenous leukemia-case presentation and review of the literature.

Ann Hematol 2011; 90(2): 235-8 


Lovric S, Kielstein JT, Kayser D, Bröcker V, Becker JU, Hiss M, Schiffer M, Sommerwerck U, Haller H, Strüber M, Welte T, Gottlieb J:

Combination of everolimus with calcineurin inhibitor medication resulted in post-transplant haemolytic uraemic syndrome in lung transplant recipients--a case series.

Nephrol Dial Transplant 2011; 26(9): 3032-8


Luetjens G, Krauss JK, Brandis A, Nakamura M:

Bilateral sphenoorbital hyperostotic meningiomas with proptosis and visual impairment: A therapeutic challenge. Report of three patients and review of the literature.

Clin Neurol Neurosurg 2011; 113(10): 859-63


Marx A, Rieker R, Toker A, Länger F, Ströbel P:

Thymic carcinoma: is it a separate entity? From molecular to clinical evidence.

Thorac Surg Clin 2011; 21(1): 25-31. v-vi.


Mengel M, Chang J, Kayser D, Gwinner W, Schwarz A, Einecke G, Broecker V, Famulski K, de Freitas DG, Guembes-Hidalgo L, Sis B, Haller H, Halloran PF:

The molecular phenotype of 6-week protocol biopsies from human renal allografts: reflections of prior injury but not future course.

Am J Transplant 2011; 11(4): 708-18


Metzger J, Chatzikyrkou C, Broecker V, Schiffer E, Jaensch L, Iphoefer A, Mengel M, Mullen W, Mischak H, Haller H, Gwinner W:

Diagnosis of subclinical and clinical acute T-cell-mediated rejection in renal transplant patients by urinary proteome analysis.

Proteomics Clin Appl 2011; 5(5-6): 322-33


Meyer-Schwesinger C, Dehde S, Klug P, Becker JU, Mathey S, Arefi K, Balabanov S, Venz S, Endlich KH, Pekna M, Gessner JE, Thaiss F, Meyer TN:

Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis.

J Immunol 2011; 187(6): 3218-29


Meyer-Schwesinger C, Lange C, Bröcker V, Andina Agustian P, Lehmann U, Raabe A, Brinkmeyer M, Kobayashi E, Schiffer M, Büsche G, Kreipe HH, Thaiss F, Becker JU:

Bone marrow-derived progenitor cells do not contribute to podocyte turnover in the puromycin aminoglycoside and renal ablation models in rats.

Am J Pathol 2011; 178(2): 494-9


Muth M, Engelhardt BM, Kröger N, Hussein K, Schlué J, Büsche G, Kreipe HH, Bock O:

Thrombospondin-1 (TSP-1) in primary myelofibrosis (PMF) - a megakaryocyte-derived biomarker which largely discriminates PMF from essential thrombocythemia.

Ann Hematol 2011; 90(1): 33-40


Nickel N, Jonigk D, Kempf T, Bockmeyer CL, Maegel L, Rische J, Laenger F, Lehmann U, Sauer C, Greer M, Welte T, Hoeper MM, Golpon HA:

GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells.

Respir Res 2011; 12: 62


Otto N, Manukjan G, Göhring G, Hofmann W, Scherer R, Luna JC, Lehmann U, Ganser A, Welte K, Schlegelberger B, Steinemann D:

ICSBP promoter methylation in myelodysplastic syndromes and acute myeloid leukaemia.

Leukemia 2011; 25(7): 1202-7


Penzel R, Sers C, Chen Y, Lehmann-Mühlenhoff U, Merkelbach-Bruse S, Jung A, Kirchner T, Büttner R, Kreipe HH, Petersen I, Dietel M, Schirmacher P:

EGFR mutation detection in NSCLC-assessment of diagnostic application and recommendations of the German Panel for Mutation Testing in NSCLC.

Virchows Arch 2011; 458(1): 95-8


Peterss S, Khaladj N, Pichlmaier M, Hoeffler K, von Wasielewski R, Shrestha ML, Haverich A, Hagl C:

Hypothermic circulation arrest with "low flow" lower body perfusion: an experimental feasibility study of microcirculatory parameters.

Thorac Cardiovasc Surg 2011; 59(6): 335 - 41


Pincha M, Salguero G, Wedekind D, Sundarasetty BS, Lin A, Kasahara N, Brugman MH, Jirmo AC, Modlich U, Gutzmer R, Büsche G, Ganser A, Stripecke R.

Lentiviral vectors for induction of self-differentiation and conditional ablation of dendritic cells.

Gene Ther 2011; 18(8): 740-64


Potapova A, Albat C, Hasemeier B, Haeussler K, Lamprecht S, Suerbaum S, Kreipe H, Lehmann U:

Systematic cross-validation of 454 sequencing and pyrosequencing for the exact quantification of DNA methylation patterns with single CpG resolution.

BMC Biotechnol 2011; 11: 6


Puls F, Agne C, Klein F, Koch M, Rifai K, Manns MP, Borlak J, Kreipe HH:

Pathology of flupirtine-induced liver injury: : a histological and clinical study of six cases.

Virchows Arch 2011; 458(6): 709-16


Schwerk N, Brinkmann F, Soudah B, Kabesch M, Hansen G:

Wheeze in Preschool Age Is Associated with Pulmonary Bacterial Infection and Resolves after Antibiotic Therapy.

PLoS ONE 2011; 6(11): e27913


Seidel C, Fenner M, Merseburger AS, Reuter C, Ivanyi P, Länger F, Ganser A, Grünwald V:

Response of renal lesions during systemic treatment with sunitinib in patients with metastatic renal cell carcinoma: a single center experience with 14 patients.

World J Urol 2011; 29(3): 355-60


Sörensen I, Rong S, Susnik N, Gueler F, Shushakova N, Albrecht M, Dittrich AM, von Vietinghoff S, Becker JU, Melk A, Bohlmann A, Reingruber S, Petzelbauer P, Haller H, Schmitt R:

Bß15-42 attenuates the effect of ischemia-reperfusion injury in renal transplantation.

J Am Soc Nephrol 2011; 22(10): 1887-96


Soudah B, Marwedel M, Schirakowski A:

[Zytologie des harnableitenden Systems.]

Cyto-Info 2011; 30(1): 3-8 [German]


Soudah B, Schirakowski A, Jonigk D:

[Zytologie der Lunge und Differentialdiagnose der Lungentumoren.]

Cyto-Info 2011; 30(3): 75-81 [German]


Steffens S, Schrader AJ, Blasig H, Vetter G, Eggers H, Trankenschuh W, Kuczyk MA, Serth J:

Caveolin 1 protein expression in renal cell carcinoma predicts survival.

BMC Urol 2011; 11(1): 25 


Steinwede K, Tempelhof O, Bolte K, Maus R, Bohling J, Ueberberg B, Länger F, Christman JW, Paton JC, Ask K, Maharaj S, Kolb M, Gauldie J, Welte T, Maus UA:

Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia.

J Immunol 2011; 187(10): 5346-56


Thie H, Toleikis L, Li J, von Wasielewski R, Bastert G, Schirrmann T, Esteves IT, Behrens CK, Fournes B, Fournier N, de Romeuf C, Hust M, Dübel S:

Rise and fall of an anti-MUC1 specific antibody.

PLoS One 2011; 6(1): e15921


Trépo E, Pradat P, Potthoff A, Momozawa Y, Quertinmont E, Gustot T, Lemmers A, Berthillon P, Amininejad L, Chevallier M, Schlué J, Kreipe H, Devière J, Manns M, Trépo C, Sninsky J,  Wedemeyer H, Franchimont D, Moreno C:

Impact of Patatin-Like Phospholipase-3 (rs738409 C>G) Polymorphism on Fibrosis Progression and Steatosis in Chronic Hepatitis C.

Hepatology 2011; 54(1): 60-9 


Valentiner U, Mühlenhoff M, Lehmann U, Hildebrandt H, Schumacher U:

Expression of the neural cell adhesion molecule and polysialic acid in human neuroblastoma cell lines.

Int J Oncol 2011; 39(2): 417-24


Veltkamp C, Anstaett M, Wahl K, Möller S, Gangl S, Bachmann O, Hardtke-Wolenski M, Länger F, Stremmel W, Manns MP, Schulze-Osthoff K, Bantel H:

Apoptosis of regulatory T lymphocytes is increased in chronic inflammatory bowel disease and reversed by anti-TNF{alpha} treatment.

Gut 2011; 60(10): 1345-53


Voigtländer T, Cornberg M, Kubitz R, Schlue J, Manns MP, Lankisch T:

Unexplained jaundice after squirrel bite. It's not what you look at that matters, it's what you see (H.D. Thoreanu).

J Gastrointestin Liver Dis 2011; 20(3): 331-2 [Case Report]


Waalkes S, Eggers H, Blasig H, Atschekzei F, Kramer MW, Hennenlotter J, Tränkenschuh W, Stenzl A, Serth J, Schrader AJ, Kuczyk MA, Merseburger AS:

Caveolin 1 mRNA is overexpressed in malignant renal tissue and might serve as a novel diagnostic marker for renal cancer.

Biomark Med 2011; 5(2): 219-25


Wagner ME, Rana M, Traenkenschuh W, Kokemueller H, Eckardt AM, Gellrich NC:

Piezoelectric-assisted removal of a benign fibrous histiocytoma of the mandible: an innovative technique for prevention of dentoalveolar nerve injury.

Head Face Med 2011; 7: 20


Wohlschläger J, Sommerwerck U, Jonigk D, Rische J, Baba HA, Müller KM:

[Lung transplantation and rejection. Basic principles, clinical aspects and histomorphology.]

Pathologe 2011; 32(2): 104-12 [German]


Wohlsein P, Baumgärtner W, Kreipe HH, Hori A, Stan AC:

[Rabies transmission through lung transplantation.]

Pathologe 2011; 32(5): 406-10 [German]


Wolters M, Kramer MW, Becker JU, Christgen M, Nagele U, Imkamp F, Burchardt M, Merseburger AS, Kuczyk MA, Bach T, Gross AJ, Herrmann TR:

Tm:YAG laser en bloc mucosectomy for accurate staging of primary bladder cancer: early experience.

World J Urol 2011; 29(4): 429-32