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Paediatric Kidney, Liver and Metabolic Diseases

Professor Dr. med. Dieter Haffner, Director of the Department of Paediatric Kidney, Liver and Metabolic Diseases


Professor Dieter Haffner is a paediatrician and physician who is responsible for clinical care, research, teaching and management at the Hannover Medical School Children`s Hospital.


He is a member of various international societies such as the International Paediatric Nephrology Asscociation and currently the Treasurer of the European Society for Paediatric Nephrology (


Internationally, Professor Haffner is involved in the cooperation and coordination of clinical research on topics such as growth and development, cardiovascular health and bone disease in children with renal disorders. He organises clinical trials, congresses, teaching courses and residencies for visiting doctors.

His clinical focus is on organ failure and transplantation medicine in children.

Professor Haffner is the director of three work groups:

* Paediatric nephrology
* Hepato-gastroenterology
* Metabolic diseases.

Organ-specific and general paediatric care is offered to patients in all three work groups, including diagnosis and therapy of growth and development failure in chronically ill children, as well as their psychosocial welfare. One of the Department`s main  focuses is on the care of children with organ failure.


As of 2011, 700 renal and 600 liver transplantations have been performed on children. Professor Haffner and his team have developed several treatments which are accepted worldwide and have become standard therapies.


Clinical Profile


Our Department is a major centre for the treatment of kidney, liver and metabolic diseases.
It has become a leader in the care of children in Europe with renal and liver transplants, focusing on transplantation in young children and adolescents, transplantation in risk groups (blood group incompatibility, multiple-organ failure, disabled children) with special focus on living organ donation and preemptive transplantation without prior dialysis.


Organ replacement therapy with peritoneal and haemodialysis is available, as well as all apheresis and liver bridging techniques. All these therapies are performed according to the highest standards in cooperation with the Curatorium for Dialysis and Kidney Transplantation (KfH- Kuratorium für Heimdialyse ).


Diagnosis and therapy is available for  children with inborn and acquired kidney and liver diseases. Diagnostic methods include biopsy with same-day results, gastro-intestinal endoscopy and high-end ultrasonography, electrophysiology, and all imaging techniques. Our own metabolic laboratory is able to analyse complex disorders of amino and organic acids and respiratory chain defects.


New diagnostic methods and surrogate markers for prognosis after organ transplantation were developed here and immunosuppressive strategies initiated.


In order to reduce co-morbidity and to ensure the complete rehabilitation and highest possible quality of life of our patients, we offer integral, neuropsychological-anthropological diagnostics for patients with organ dysfunction.


Professor Haffner’s Department specialises in the  care of children with rare, complicated and complex illnesses with multiple organ involvement, with a special focus on:


      Congenital and acquired kidney diseases, e.g. nephrotic syndrome,   renal   failure, cystic kidney diseases and kidney transplantation


     Liver and biliary tract diseases, e.g. biliary atresia, hepatitis, liver cirrhosis, liver transplantation, chronic intestinal diseases


     Metabolic diseases, congenital metabolic defects, disorders of the brain (epilepsy) and growth failure


Professor Haffner’s team consists of 23 physicians and 50 nursing staff.


As a leading university hospital, the Department is fully equipped up to the latest technical standards.


Facilities are available for the accomodation of a parent and child in a private room.


Scientific Profile


The excellent clinical work of the department is based on the research of more than 20 dedicated scientists. Research groups on congenital and acquired kidney and liver diseases, neurological and metabolic disorders focus on the cause of these diseases, while also continuing to develop innovative diagnostic and treatment strategies. A major topic is also the improvement of liver and kidney transplantation with respect to growth and development, cardiovascular health and cognitive development. We have established non-invasive methods for assessment of endothelial function and also applied this technique to other diseases known for the development of cardiovascular lesions.


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