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Publikationen von Andreas Krueger in PubMed:


Koenecke C, Heim D, van Biezen A, Heuser M, Aljurf M, Kyrcz-Krzemien S, Volin
Lee CW, Wohlan K, Dallmann I, Förster R, Ganser A, Krueger A, Scherr M, Eder M, Koenecke C. miR-181a Expression in Donor T Cells Modulates Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation. J Immunol. 2016 Mar 23. pii: 1502152. [Epub ahead of print] PubMed PMID: 27009493.


Sandrock I, Ziętara N, Łyszkiewicz M, Oberdörfer L, Witzlau K, Krueger A*, Prinz I*. MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development. PLoS One. 2015 Dec 16;10(12):e0145010. doi: 10.1371/journal.pone.0145010. eCollection 2015. PubMed PMID: 26673421. *equal contribution 

Regelin M, Blume J, Pommerencke J, Vakilzadeh R, Witzlau K, Łyszkiewicz M, Ziętara N, Saran N, Schambach A, Krueger A (2015). Responsiveness of Developing T Cells to IL-7 Signals Is Sustained by miR-17∼92. J Immunol. 2015 Oct 16. PMID: 26475928

Ziętara N, Łyszkiewicz M, Puchałka J, Witzlau K, Reinhardt A, Förster R, Pabst O, Prinz I, Krueger A. (2015). Multicongenic fate mapping quantification of dynamics of thymus colonization. J Exp Med. 212:1589-601. PMID: 26347471

Łyszkiewicz M, Ziętara N, Föhse L, Puchałka J, Diestelhorst J, Witzlau K, Prinz I, Schambach A, Krueger A. (2015). Limited niche availability suppresses murine intrathymic dendritic-cell development from non-committed progenitors. Blood, 125:457-64, doi: 10.1182/blood-2014-07-592667.


Ugur M, Schulz O, Menon MB, Krueger A, Pabst O (2014). Resident CD4+ T cells accumulate in lymphoid organs after prolonged antigen exposure. Nat Commun 5:4821. doi: 10.1038/ncomms5821.

Braune EB, Schuster-Gossler K, Lyszkiewicz M, Serth K, Preuße K, Madlung J, Macek B, Krueger A, Gossler A (2014). S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function during embryonic patterning and marginal zone B cell development. Mol Cell Biol. 34:1221-33.

Ziętara N, Lyszkiewicz M, Krueger A*, Weiss S* (2014). B-cell modulation of dendritic-cell function: Signals from the far side. Eur J Immunol, 44, 23-32. doi: 10.1002/eji.201344007. * Corresponding authors.

Schulz O, Ugur M, Friedrichsen M, Radulovic K, Niess JH, Jalkanen S, Krueger A, Pabst O (2014). Hypertrophy of infected Peyer's patches arises from global, interferon-receptor, and CD69-independent shutdown of lymphocyte egress. Mucosal Immunol 7:892-904.


Ziętara N, Łyszkiewicz M, Witzlau K, Naumann R, Hurwitz R, Langemeier J, Bohne J, Sandrock I, Ballmaier M, Weiss S, Prinz I*, and Krueger A* (2013). Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells. Proc. Natl. Acad. Sci. USA 110:7407-7412.* Equal contribution.


Ziętara N, Łyszkiewicz M, Puchałka J, Gutierrez MG, Pei G, Lienenklaus S, Hobeika E, Reth, M, Martins Dos Santos VAP, Krueger A*, and Weiss S* (2013). Immunoglobulins drive terminal maturation of splenic dendritic cells. Proc. Natl. Acad. Sci. USA 110:2282-2287. * Equal contribution.





Ziętara N, Łyszkiewicz M, Krueger A, and Weiss S. (2011). ICOS-dependent stimulation of NKT cells by marginal zone B cells. Eur J Immunol, 41, 3125-3134.


Krueger, A. (2011). A missing link in thymic dendritic cell development. Eur J Immunol, 41, 2145-2147.


Haas, J. D., Nistala, K., Petermann, F., Saran, N., Chennupati, V., Schmitz, S., Korn, T., Wedderburn, L. R., Förster, R., Krueger, A.*, and Prinz, I*. (2011). Expression of miRNAs miR-133b and miR-206 in the Il17a/f locus is co-regulated with IL-17 production in αβ and γδ T cells. PLoS One, 6(5), e20171. (* Equal contribution).


Surdziel, E., Cabanski, M., Dallmann, I., Łyszkiewicz, M., Krueger, A., Ganser, A., Scherr, M., and Eder, M. (2011). Enforced expression of miR-125b affects myelopoiesis by targeting multiple signalling pathways. Blood 117, 4338-48.


Łyszkiewicz, M., Witzlau, K., Pommerencke, J., and Krueger, A. (2011). Chemokine receptor CX3CR1 promotes dendritic cell development under steady-state conditions. Eur J Immunol, 41, 1256-65.





Krueger, A., Willenzon, S., Łyszkiewicz, M., Kremmer, E., and Förster, R. (2010). CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus. Blood 115, 1906-1912.


Saran, N., Łyszkiewicz, M., Pommerencke, J., Witzlau, K., Vakilzadeh, R., Ballmaier, M., von Boehmer, H., and Krueger, A. (2010). Multiple extrathymic precursors contribute to T-cell development with different kinetics. Blood 115, 1137-1144.




Weber, C.*, Krueger, A.*, Münk, A., Bode, C., Van Veldhoven, P. P., and Gräler, M. H. (2009). Discontinued postnatal thymocyte development in sphingosine 1-phosphate-lyase-deficient mice. J Immunol 183, 4292-4301. * Equal contribution




Kreslavsky, T., Garbe, A. I., Krueger, A., and von Boehmer, H. (2008). T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis. J Exp Med 205, 1173-1186.




Junt, T., Schulze, H., Chen, Z., Massberg, S., Goerge, T., Krueger, A., Wagner, D. D., Graf, T., Italiano, J. E., Shivdasani, R. A., and von Andrian, U. H. (2007). Dynamic visualization of thrombopoiesis within bone marrow. Science 317, 1767-1770.


Krueger, A., and von Boehmer, H. (2007). Identification of a T lineage-committed progenitor in adult blood. Immunity 26, 105-116.




Krueger, A., Garbe, A. I., and von Boehmer, H. (2006). Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. J Exp Med 203, 1977-1984.


Dose, M., Khan, I., Guo, Z., Kovalovsky, D., Krueger, A., von Boehmer, H., Khazaie, K., and Gounari, F. (2006). c-Myc mediates pre-TCR-induced proliferation but not developmental progression. Blood 108, 2669-2677.


Garbe, A. I.*, Krueger, A.*, Gounari, F., Zuniga-Pflucker, J.-C., and von Boehmer, H. (2006). Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate. J Exp Med 203, 1579-1590. * Equal contribution


Fas, S. C., Baumann, S., Krueger, A., Frey, C. R., Schulze-Bergkamen, H., Brenner, D., Stumpf, C., Kappes, K., and Krammer, P. H. (2006). In vitro generated human memory-like T cells are CD95 type II cells and resistant towards CD95-mediated apoptosis. Eur J Immunol 36, 2894-2903.


Krueger, A.*, Fas, S. C.*, Giaisi, M., Bleumink, M., Merling, A., Stumpf, C., Baumann, S., Holtkotte, D., Bosch, V., Krammer, P. H., and Li-Weber, M. (2006). HTLV-1 Tax protects against CD95-mediated apoptosis by induction of the cellular FLICE-inhibitory protein (c-FLIP). Blood 107, 3933-3939. * Equal contribution


Golks, A., Brenner, D., Schmitz, I., Watzl, C., Krueger, A., Krammer, P. H., and Lavrik, I. N. (2006). The role of CAP3 in CD95 signaling: new insights into the mechanism of procaspase-8 activation. Cell Death Differ 13, 489-498.




Baumann, S., Dostert, A., Novac, N., Bauer, A., Schmid, W., Fas, S. C., Krueger, A., Heinzel, T., Kirchhoff, S., Schütz, G., and Krammer, P. H. (2005). Glucocorticoids inhibit activation-induced cell death (AICD) via direct DNA-dependent repression of the CD95 ligand gene by a glucocorticoid receptor dimer. Blood 106, 617-625.


Beier, C., Wischhusen, J., Gleichmann, M., Gerhardt, E., Pekanovic, A., Krueger, A., Taylor, V., Suter, U., Krammer, P. H., Endres, M., et al. (2005). FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35. J Neurosci 25, 6765-6774.




Schulze-Bergkamen, H., Brenner, D., Krueger, A., Suess, D., Fas, S. C., Frey, C. R., Dax, A., Zink, D., Büchler, P., Müller, M., and Krammer, P. H. (2004). Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt. Hepatology 39, 645-654.


Eichhorst, S. T.*, Krueger, A.*, Müerköster, S., Fas, S. C., Golks, A., Gruetzner, U., Schubert, L., Opelz, C., Bilzer, M., Gerbes, A. L., and Krammer, P. H. (2004). Suramin inhibits death receptor-induced apoptosis in vitro and fulminant apoptotic liver damage in mice. Nat Med 10, 602-609. * Equal contribution


Ganten, T. M., Haas, T. L., Sykora, J., Stahl, H., Sprick, M. R., Fas, S. C., Krueger, A., Weigand, M. A., Grosse-Wilde, A., Stremmel, W., et al. (2004). Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. Cell Death Differ 11 Suppl 1, S86-96.


Finzer, P., Krueger, A., Stöhr, M., Brenner, D., Soto, U., Kuntzen, C., Krammer, P. H., and Rösl, F. (2004). HDAC inhibitors trigger apoptosis in HPV-positive cells by inducing the E2F-p73 pathway. Oncogene 23, 4807-4817.


Schmitz, I., Weyd, H., Krueger, A., Baumann, S., Fas, S. C., Krammer, P. H., and Kirchhoff, S. (2004). Resistance of short term activated T cells to CD95-mediated apoptosis correlates with de novo protein synthesis of c-FLIPshort. J Immunol 172, 2194-2200.




Krueger, A., Fas, S. C., Baumann, S., and Krammer, P. H. (2003). The role of CD95 in the regulation of peripheral T-cell apoptosis. Immunol Rev 193, 58-69.


Lavrik, I. N., Krueger, A., Schmitz, I., Baumann, S., Weyd, H., Krammer, P. H., and Kirchhoff, S. (2003). The active caspase-8 heterotetramer is formed at the CD95 DISC. Cell Death Differ 10, 144-145.


Baumann, S., Hess, J., Eichhorst, S. T., Krueger, A., Angel, P., Krammer, P. H., and Kirchhoff, S. (2003). An unexpected role for FosB in activation-induced cell death of T cells. Oncogene 22, 1333-1339.


Schmitz, I.*, Krueger, A.*, Baumann, S., Schulze-Bergkamen, H., Krammer, P. H., and Kirchhoff, S. (2003). An IL-2-dependent switch between CD95 signaling pathways sensitizes primary human T cells toward CD95-mediated activation-induced cell death. J Immunol 171, 2930-2936. * Equal contribution




Schmitz, I.*, Krueger, A.*, Baumann, S., Kirchhoff, S., and Krammer, P. H. (2002). Specificity of anti-human CD95 (APO-1/Fas) antibodies. Biochem Biophys Res Commun 297, 459-462. * Equal contribution


Baumann, S., Krueger, A., Kirchhoff, S., and Krammer, P. H. (2002). Regulation of T cell apoptosis during the immune response. Curr Mol Med 2, 257-272.


Hentze, H., Schmitz, I., Latta, M., Krueger, A., Krammer, P. H., and Wendel, A. (2002). Glutathione dependence of caspase-8 activation at the death-inducing signaling complex. J Biol Chem 277, 5588-5595.


Kirchhoff, S., Sebens, T., Baumann, S., Krueger, A., Zawatzky, R., Li-Weber, M., Meinl, E., Neipel, F., Fleckenstein, B., and Krammer, P. H. (2002). Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-regulatory factor 1-dependent domains in the CD95 ligand promoter. J Immunol 168, 1226-1234.




Krueger, A., Baumann, S., Krammer, P. H., and Kirchhoff, S. (2001). FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis. Mol Cell Biol 21, 8247-8254.


Chatterjee, D., Schmitz, I., Krueger, A., Yeung, K., Kirchhoff, S., Krammer, P. H., Peter, M. E., Wyche, J. H., and Pantazis, P. (2001). Induction of apoptosis in 9-nitrocamptothecin-treated DU145 human prostate carcinoma cells correlates with de novo synthesis of CD95 and CD95 ligand and down-regulation of c-FLIP(short). Cancer Res 61, 7148-7154.


Eckhart L., Henry M., Santos-Beneit A. M., Schmitz I., Krueger A., Fischer H., Bach J., Ban J., Kirchhoff S., Krammer P. H., Mollinedo F., Tschachler E. (2001). Alternative splicing of caspase-8 mRNA during differentiation of human leukocytes. Biochem Biophys Res Commun 289, 777-781.


Krueger, A., Schmitz, I., Baumann, S., Krammer, P. H., and Kirchhoff, S. (2001). Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex. J Biol Chem 276, 20633-20640.




Kirchhoff, S., Müller, W. W., Krueger, A., Schmitz, I., and Krammer, P. H. (2000). TCR-mediated up-regulation of c-FLIPshort correlates with resistance toward CD95-mediated apoptosis by blocking death-inducing signaling complex activity. J Immunol 165, 6293-6300.



AG Krüger






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