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Busley D, Ochs M, Hoeltig D, Ganter M, Acevedo C, Schmiedl A, Hennig-Pauka I (2016):
Characterization of surfactant alterations in pigs infected with Actinobacillus pleuropneumoniae
Exp Lung Res. 14:1-13 PubMed


Funke M, Knudsen L, Lagares D, Ebener S, Probst CK, Fontaine BA, Franklin A, Kellner M, Kühnel M, Matthieu S, Grothausmann R, Chun J, Roberts JD, Ochs M, Tager AM (2016):
Lysophosphatidic Acid Signaling through the Lysophosphatidic Acid-1 Receptor Is Required for Alveolarization
Am J Respir Cell Mol Biol 55, no. 1. 105–116. DOI:10.1165/rcmb.2015-0152OC


Grothausmann R, Knudsen L, Ochs M, Mühlfeld C (2016):
Digital 3D Reconstructions Using Histological Serial Sections of Lung Tissue Including the Alveolar Capillary Network
AJP-Lung, DOI: 10.1152/ajplung.00326.2016


Grothausmann R (2016):
Providing Values of Adjacent Voxel with vtkDiscreteMarchingCubes
The VTK Journal, 975, 5,


Kellner M, Heidrich M, Lorbeer RA, Antonopoulos GC, Knudsen L, Wrede C, Izykowski N, Grothausmann R, Jonigk D, Ochs M, Ripken T, Kühnel MP, Meyer H (2016):
A Combined Method for Correlative 3D Imaging of Biological Samples from Macro to Nano Scale
Scientific Reports, 6, 35606 DOI:10.1038/srep35606


Hawi N, Reinhold A, Suero EM, Liodakis E, Przyklenk S, Brandes J, Schmiedl A, Krettek C, Meller R (2016):
The Anatomic Basis for the Arthroscopic Latarjet Procedure: A Cadaveric Study
Am J Sports Med. 44(2):497-503


Ochs M, Knudsen L, Hegermann J, Wrede C, Grothausmann R, Mühlfeld C (2016):
Using Electron Microscopes to Look into the Lung
Histochemistry and Cell Biology, DOI:10.1007/s00418-016-1502-z


Pabst R, Schmiedl A, Schrieber S, Tschernig T, Pabst VC (2016):
Ceremonies of gratitude following the dissection course: A report on procedures in departments of anatomy in German speaking countries
Ann Anat. 210:18-24


Plaass C, Claassen L, Daniilidis K, Fumy M, Stukenborg-Colsman C, Schmiedl A, Ettinger S (2016):
Placement of Plantar Plates for Lapidus Arthrodesis: Anatomical Considerations
Foot Ankle Int. 37(4):427-32.


Schmiedl A (2016):
Topografische Anatomie der Orbita. In Orbita, interdisziplinäres Management der Orbitaerkrankungen
Kap. 1, 13-34. Hrsg:  Welkoborsky, H-J, Wiechens B, Hinni ML, Thieme, Stuttgart





Birkelbach B, Lutz D, Ruppert C, Henneke I, Lopez-Rodriguez E, Günther A, Ochs M, Mahavadi P, Knudsen L (2015):
Linking progression of fibrotic lung remodeling and ultrastructural alterations of alveolar epithelial type II cells in the amiodarone mouse model
Am J Physiol (Lung Cell Mol Physiol) 309:L63-L75 PubMed


Grothausmann R, Beare R (2015):Facet Analyser: ParaView plugin for automated facet detection and measurement of interplanar angles of tomographic objectsThe MIDAS Journal, 951, URL:


Grothausmann R. Kellner M, Heidrich M, Lorbeer R-A, Ripken T, Meyer H, Kuehnel MP, Ochs M, Rosenhahn B (2015):
Method for 3D Airway Topology Extraction
Computational and Mathematical Methods in Medicine, 2015 DOI: 10.1155/2015/127010


Hawi N, Reinhold A, Suero EM, Liodakis E, Przyklenk S, Brandes J, Schmiedl A, Krettek C, Meller R (2015):
The Anatomic Basis for the Arthroscopic Latarjet Procedure
Am J Sports Med. PubMed


Holm AT, Wulf-Johansson H, Hvidsten S, Jorgensen PT, Schlosser A, Pilecki B, Ormhoj M, Moeller JB, Johannsen C, Baun C, Andersen T, Schneider JP, Hegermann J, Ochs M, Götz A, Schulz H, Hrabe de Angelis M, Vestbo J, Holmskov U, Sorensen GL (2015):
Characterization of spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4
Am J Physiol (Lung Cell Mol Physiol) 208:L1114-L1124 PubMed


Katsirntaki K, Mauritz C, Olmer R, Schmeckebier S, Sgodda M, Puppe V, Duerr J, Eggenschwiler R, Schubert SC, Schmiedl A, Ochs M, Cantz T, Mall M, Salwig I, Szibor M, Rathert C, Martens A, Braun T, Martin U (2015):
Bronchoalveolar sublineage specification of pluripotent stem cells: effect of dexamethasone plus cAMP-elevating agents and keratinocyte growth factor
Tissue Eng A 21:669-682 PubMed


Kellner M, Wehling J, Warnecke G, Heidrich M, Izykowski N, Vogel-Claussen J, Lorbeer R-A, Antonopoulos G, Janciauskiene S, Grothausmann R, Knudsen L, Ripken T, Meyer H, Kreipe H, Ochs M, Jonigk D, Kühnel M P (2015):
Correlating 3D morphology with molecular pathology: fibrotic remodelling in human lung biopsies
Thorax  70:1197-1198 PubMed


Kupsch A, Lange A, Hentschel M P, Lück S, Schmidt V, Grothausmann R, Hilger A, Manke I (2015):
Missing wedge computed tomography by iterative algorithm DIRECTT
Journal of Microscopy 261: 36-45 PubMed


Lange A, Kupsch A, Hentschel M P, Lück S, Schmidt V, Grothausmann R, Hilger A, Manke I (2015):
Reduzierung von Missing-Wedge-Artefakten mit DIRECTT
DGZfP Proceedings DGZfP-Jahrestagung 2014 20 URL


Lutz D, Gazdhar A, Lopez-Rodriguez E, Ruppert C, Mahavadi P, Günther A, Klepetko W, Bates JH, Smith B, Geiser T, Ochs M, Knudsen L (2015):
Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis
Am J Respir Cell Mol Biol 52:232-243 PubMed


Manke I, Kardjilov N, Schäfer R, Hilger A, Grothausmann R, Strobl M, Dawson M, Grünzweig C, Tötzke C, David C, Kupsch A, Lange A, Hentschel MP, Banhart J (2015):
Three-Dimensional Imaging of Magnetic Domains with Neutron Grating Interferometry
Physics Procedia 69:404-412 DOI


McDonough JE, Knudsen L, Wright AC, Elliott WM, Ochs M, Hogg JC (2015):
Regional differences in alveolar density in the human lung are related to lung height
J Appl Physiol 118:1429-1434 PubMed


Plaass C, Claassen L, Daniilidis K, Fumy M, Stukenborg-Colsman C, Schmiedl A, Ettinger S (2015):
Placement of Plantar Plates for Lapidus Arthrodesis: Anatomical Considerations
Foot Ankle Int. PubMed


Schneider JP, Pedersen L, Mühlfeld C, Ochs M (2015):
Staining histological lung sections with Sudan Black B or Sudan III for automated identification of alveolar epithelial type II cells.
Acta Histochem. 2015 Oct;117(8):675-80 PubMed


Willführ A, Brandenberger C, Piatkowski T, Grothausmann R, Nyengaard J R, Ochs M, Mühlfeld C (2015):
Estimation of the number of alveolar capillaries by the Euler number (Euler-Poincaré characteristic)
American Journal of Physiology - Lung Cellular and Molecular Physiology 309: L1286-L1293 PubMed



Bang C, Batkai S, Dangwal S, Gupta SK, Foinquinos A, Holzmann A, Just A, Remke J, Zimmer K, Zeug A, Ponimaskin E, Schmiedl A, Yin X, Mayr M, Halder R, Fischer A, Engelhardt S, Wei Y, Schober A, Fiedler J, Thum T (2014):
Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy.
J Clin Invest:124(5):2136-46 PubMed


Grothausmann R (2014):
Extracting Intersections of Coplanar Surfaces (Boolean-operation on touching meshes)
The VTK Journal, 949, URL:


Herrmann G, Knudsen L, Madershahian N, Mühlfeld C, Frank K, Rahmanian P, Wahlers T, Wittwer T, Ochs M (2014):
Effects of exogenous surfactant on the non-heart-beating donor lung graft in experimental lung transplantation - a stereological study.
J Anat 224:594-602 PubMed


Hupa KL, Schmiedl A, Pabst R, von Hörsten S, Stephan M (2014):
Maternal deprivation decelerates postnatal morphological lung development of F344 rats.
Anat. Rec 297(2):317-26 PubMed


Johnson L, Montgomery JB, Schneider JP, Townsend HG, Ochs M, Singh B (2014):
Morphometric examination of the equine adult and foal lung.
Anat Rec (Hoboken) 297: 1950-1962, 2014 PubMed


Jungheim M, Miller S, Kühn D, Schwemmle C, Schneider JP, Ochs M, Ptok M (2014):
Anatomie des oberen Ösophagussphinkters.
HNO 62:385-394 PubMed


Jungheim M, Miller S, Kühn D, Schwemmle C, Schneider JP, Ochs M, Ptok M (2014):
Physiologie des oberen Ösophagussphinkters.
HNO 62:457-468 PubMed


Kegler K, Imbschweiler I, Ulrich R, Kovermann P, Fahlke C, Deschl U, Kalkuhl A, Baumgärnter W, Wewetzer K (2014):
CNS Schwann cells display oligodendrocyte precursor-like potassium channel activation and antigenic expression in vitro.
J Neural Transm 121(6):569-81 PubMed


Knudsen L, Atochina-Vasserman EN, Guo CJ, Scott P, Haenni B, Beers MF, Ochs M, Gow A (2014):
NOS2 is critical to the development of emphysema in Sftpd deficient mice but does
not affect surfactant homeostasis.
PLoS One 9:e85722:1-10 PubMed


Lange A, Hentschel M P, Kupsch A, Hilger A, Manke I, Lück S, Schmidt V, Grothausmann R (2014):
Reduction of Missing Wedge Artifacts in Computerised Tomography by DIRECTT
MP Materials Testing, 56, 716-721, DOI: 10.3139/120.110612


Minocchieri S, Knoch S, Schoel WM, Ochs M, Nelle M (2014):
Nebulizing poractant alfa versus conventional instillation: ultrastructural appearance and preservation of surface activity.
Ped Pulmonol 49:348-356 PubMed


Mühlfeld C, Ochs M (2014):
Measuring structure - What´s the point in counting?
Ann Anat 196:1-2 PubMed


Ochs M (2014):
Estimating structural alterations in animal models of lung emphysema. Is there a gold standard?
Ann Anat 196:26-33 PubMed


Schneider JP, Ochs M (2014):
Alterations of mouse lung tissue dimensions during processing for morphometry - a comparison of methods.
Am J Physiol (Lung Cell Mol Physiol) 306:L341-L350 PubMed


Schmiedl A, Grützner D, Hoffmann T, von Hörsten S, Stephan M (2014):
DPP4 Inhibitors increase differentially the expression of surfactant proteins in Fischer 344 rats
Acta Physiol (Oxf).: 212(3):248-61 PubMed


Tschanz S, Schneider JP, Knudsen L (2014):
Design-based stereology: Planning, volumetry and sampling are crucial steps for a successful study.
Ann Anat. 196(1):3-11 PubMed


Ulrich R, Imbschweiler I, Kalkuhl A, Lehmbecker A, Ziege S, Kegler K, Becker K, Deschl U, Wewetzer K, Baumgärtner W (2014):
Transcriptional profiling predicts overwhelming homology of Schwann cells, olfactory ensheathing cells, and Schwann cell-like glia.
Glia 62(10):1559-81 PubMed


Ulrich R, Puff C, Wewetzer K, Kalkuhl A, Deschl U, Baumgärtner W (2014):
Transcriptional changes in canine distemper virus-induced demyelinating leukoencephalitis favor a biphasic mode of demyelination.
PLoS One 9(4):e95917 PubMed


Winkler C, Bahlmann O, Viereck J, Knudsen L, Wedekind D, Hoymann HG, Madsen J, Thum T, Hohlfeld JM, Ochs M (2014):
Impact of a Met(11)Thr single nucleotide polymorphism of surfactant protein D on allergic airway inflammation in a murine asthma model.
Exp Lung Res 40:154-163 PubMed



Adam RJ, Michalski AS, Bauer C, Abou Alaiwa MH, Gross TJ, Awadalla MA, Bouzek DC, Gansemer ND, Taft PJ, Hoegger MJ, Diwakar A, Ochs M, Reinhardt JM, Hoffman EA, Beichel RR, Meyerholz DK, Stoltz DA (2013):
Air trapping and airway obstruction in newborn cystic fibrosis pigs.
Am J Respir Crit Care Med 188:1434-1441 PubMed


Arlt T, Grothausmann R, Manke I, Markötter H, Krüger P, Haussmann J, Hilger A, Kardjilov N, Hartnig C, Kupsch A, Lange A, Hentschel M P, Tötzke C, Wippermann K, Banhart J (2013):
Tomographic methods for fuel cells research (Tomografische Methoden für die Brennstoffzellenforschung)
MP Materials Testing; 3, 207-213 URL


Dettmer S, Schmiedl A, Meyer S, Giesemann A, Pabst R, Weidemann J, Wacker FK,  Kirchhoff T (2013):
Radiological anatomy - evaluation of integrative education in radiology.
Rofo 185:838-843 PubMed


Ebel C, Brandes G, Radtke C, Rohn K, Wewetzer K (2013):
Clonal in vitro analysis of neurotrophin receptor p75-immunofluorescent cells reveals phenotypic plasticity of primary rat olfactory ensheathing cells.
Neurochem Res 38:1078-1087 PubMed


Gazdhar A, Susuri N, Hostettler K, Gugger M, Knudsen L, Roth M, Ochs M, Geiser T (2013):
HGF expressing stem cells in usual interstitial pneumonia originate from the bone marrow and are antifibrotic.
PLoS One 8:e65453:1-13 DOI: 10.1371/journal.pone.0065453


Gazdhar A, Temuri A, Knudsen L, Gugger M, Schmid RA, Ochs M, Geiser T (2013):
Targeted gene transfer of hepatocyte growth factor to alveolar type II epithelial cells reduces lung fibrosis in rats.
Hum Gene Ther 24:105-116 PubMed


Gortner L, Monz D, Mildau C, Shen J, Kasoha M, Laschke MW, Roolfs T, Schmiedl A, Meier C, Tutdibi E. (2013)
Bronchopulmonary dysplasia in a double-hit mouse model induced by intrauterine hypoxia and postnatal hyperoxia: closer to clinical features?
Ann Anat 195:351-358 PubMed


Kensah G, Roa Lara A, Dahlmann J, Zweigerdt R, Schwanke K, Hegermann J, Skvorc D, Gawol A, Azizian A, Wagner S, Maier LS, Krause A, Dräger G, Ochs M, Haverich A, Gruh I, Martin U (2013):
Murine and human pluripotent stem cell-derived cardiac bodies form contractile myocardial tissue in vitro.
Eur Heart J 34:1134-1146 PubMed


Knudsen L, Ochs K, Boxler L, Tornoe I, Sorensen G, Mackay RM, Clark H, Holmskov U, Ochs M, Madsen J (2013):
Surfactant protein D (SP-D) deficiency is attenuated in humanized mice expressing the Met(11)Thr short nucleotide polymorphism of SP-D: implications for surfactant metabolism in the lung.
J Anat 223:581-592 PubMed


Krüger M, Zinne N, Zhang R, Schneider JP, Heckmann A, Haverich A, Petersen C (2013):
Multidirectional thoracic wall stabilization: a new device on the scene.
Ann Thorac Surg. 96(5):1846-9 PubMed


Monz D, Tutdibi E, Mildau C, Shen J, Kasoha M, Laschke MW, Roolfs T, Schmiedl A, Tschernig T, Bieback K, Gortner L (2013):
Human umbilical cord blood mononuclear cells in a double-hit model of bronchopulmonary dysplasia in neonatal mice.
PLoS One 19;8(9):e74740 PubMed


Mouton WG, Habegger A, Haenni B, Tschanz S, Baumgartner I, Ochs M (2013):
Valve disease in chronic venous disorder. A quantitative ultrastructural analysis by transmission electron microscopy and stereology.
Swiss Med Wkly 143:w13755 PubMed


Mühlfeld C, Knudsen L, Ochs M (2013):
Stereology and morphometry of lung tissue.
In: Cell imaging techniques: Methods and protocols, 2nd ed. (Taatjes DJ, Roth J, eds.) Methods in molecular biology, vol. 931. Humana Press, New York: 367-390 PubMed


Mühlfeld C, Ochs M (2013):
Quantitative microscopy of the lung - a problem-based approach. Part 2: Stereological parameters and study designs in various diseases of the respiratory tract.
Am J Physiol (Lung Cell Mol Physiol) 305:L205-L221 PubMed


Ochs M (2013):
Rebuilding the lung: signals for a complex architectural task.
J Appl Physiol 114:959-960 PubMed


Ochs M, Mühlfeld C (2013):
Quantitative microscopy of the lung - a problem-based approach. Part 1: Basic principles of lung stereology.
Am J Physiol (Lung Cell Mol Physiol) 305:L15-L22 PubMed


Omar M, Hansmann F, Kreutzer R, Kreutzer M, Brandes G, Wewetzer K (2013):
Cell type- and isotype-specific expression and regulation of β-tubulins in primary olfactory ensheathing cells and Schwann cells in vitro.
Neurochem Res 38:981-988 PubMed


Plaass C, Abuharbid G, Waizy H, Ochs M, Stukenborg-Colsman C, Schmiedl A. (2013):
Anatomical variations of the flexor hallucis longus and flexor digitorum longus in the chiasma plantare
Foot Ankle Int 34(11):1580-1587 PubMed


Roloff F, Ziege S, Baumgärtner W, Wewetzer K, Bicker G (2013):
Schwann cell-free adult canine olfactory ensheathing cell preparations from olfactory bulb and mucosa display differential migratory and neurite growth-promoting properties in vitro.
BMC Neurosci 14:141 PubMed


Schmeckebier S, Mauritz C, Katsirntaki K, Sgodda M, Puppe V, Duerr J, Schubert S, Schmiedl A, Lin Q, Palacek J, Draeger G, Ochs M, Zenke M, Cantz T, Mall M, Martin U (2013):
Keratinocyte growth factor and dexamethasone plus elevated cAMP levels synergistically support pluripotent stem cell differentiation into alveolar epithelial type II cells.
Tissue Eng A 19:938-951 PubMed


Schneider JP, Ochs M (2013):
Stereology of the lung.
In: Laboratory methods in cell biology: imaging. (Conn PM, ed.) Methods in cell biology, vol. 113. Elsevier, Oxford: 257-294 PubMed


Stephan M, Suhling H, Schade J, Wittlake M, Tasic T, Klemann C, Pabst R, Jurawitz MC, Raber KA, Hoymann HG, Braun A, Glaab T, Hoffmann T, Schmiedl A, von Hörsten S (2013):
Effects of dipeptidyl peptidase-4 inhibition in an animal model of experimental asthma: a matter of dose, route, and time
Physiol Rep 1(5):e00095. doi: 10.1002/phy2.95. Epub PubMed


Vasilescu D, Klinge C, Knudsen L, Yin L, Wang G, Weibel ER, Ochs M, Hoffman EA (2013):
Stereological assessment of mouse lung parenchyma via non-destructive multi-scale micro CT imaging validated by light microscopic histology.
J Appl Physiol 114:716-724 PubMed


Wittwer T, Madershahian N, Rahmanian P, Choi YH, Neef K, Frank K, Müller-Ehmsen J, Ochs M, Mühlfeld C, Wahlers T (2013):
Surfactant application in experimental lung transplantation.
J Heart Lung Transplant 32:355-359 PubMed


Ziege S, Baumgärtner W, Wewetzer K (2013):
Toward defining the regenerative potential of olfactory mucosa: establishment and in vitro characterization of adult canine olfactory ensheathing cell preparations suitable for transplantation.
Cell Transplant; 22(2):355-67 PubMed


Alten L, Schuster-Gossler K, Beckers A, Groos S, Ulmer B, Hegermann J, Ochs M, Gossler A (2012):
Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1
Development 139:1276-1284 PubMed


Bartels H, Docker MF, Fazekas U, Potter IC (2012):
Functional and evolutionary implications of the cellular composition of the gill epithelium of feeding adults of a freshwater parasitic species of lamprey, Ichthyomyzon unicuspis.
Can J Zool 90:1278-1283, DOI: 10.1139/z2012-089


Büttner M, Bode U. (2012):
Lymph node dissection – understanding the immunological function of lymph nodes.
Clin Exp Immunol 169(3):205-12 PubMed


Burckhardt W, Kraft S, Ochs M, Proquitte H, Mense L, Rüdiger M (2012):
Persurf, a new method to improve surfactant delivery: a study in surfactant depleted rats.
PLoS One 7(19):e47923 PubMed


Düvel A, Frank C, Schnapper A, Schuberth H-J, Sipka A (2012):
Classically or alternatively activated bovine monocyte-derived macrophages in vitro do not resemble CD163/Calprotectin biased marophage populations in the teat.
Innate Immunity 18, 886-896 PubMed


Emmrich S, Henke K, Hegermann J, Ochs M, Reinhardt D, Klusmann JH (2012):
miRNAs can increase the efficiency of ex vivo platelet generation.
Ann Hematol 91:1673-1684 PubMed


Frenzel E, Korenbaum E, Hegermann J, Ochs M, Koepke J, Koczulla AR, Welte T, Köhnlein T, Janciauskiene S (2012):
Does augmentation with alpha1-antitrypsin affect neutrophil extracellular traps formation?
Int J Biol Sci 8:1023-1025 PubMed


Gerhauser I, Hahn K, Baumgärtner W, Wewetzer K (2012):
Culturing adult canine sensory neurons to optimise neural repair.
Vet Rec. 2012 Jan;170(4):102. PubMed


Gerhauser I, Hansmann F, Puff C, Kumnok J, Schaudien D, Wewetzer K, Baumgärtner W (2012):
Theiler's murine encephalomyelitis virus induced phenotype switch of microglia in vitro.
J Neuroimmunol 252(1-2):49-55 PubMed


Graulich T, Das  SK, Krasteva G, Ruppert C, Wessels L, Hoefler G, Mühlfeld C (2012):
Cancer cachexia alters intracellular surfactant metabolism but not total alveolar surface area.
Histochem Cell Biol 138(5):803-13 PubMed


Grothausmann R, Fiechter S, Beare R, Lehmann G, Kropf H, Kumar G. S. V, Manke I, Banhart J (2012):
Automated quantitative 3D analysis of faceting of particles in tomographic datasets
Ultramicroscopy 2012, 122:65-75, DOI: 10.1016/j.ultramic.2012.07.024


Grothausmann R, Gout J, Kühnel M (2012):
Voxelizer plug-in for Blender
MIDAS Journal 2012, 882, URL:


Gruber C, Kohlstedt K, Loot AE, Fleming I, Kummer W, Mühlfeld C (2012):
Stereological characterization of left ventricular cardiomyocytes, capillaries and innervation in the non-diabetic, obese mouse.
Cardiovasc Pathol 21 (4): 346-354.


Gruber C, Nink N, Nikam S, Magdowski, G, Kripp G, Voswinckel R, Mühlfeld C (2012):
Myocardial remodelling in left ventricular atrophy induced by caloric restriction
J Anat. 2012 Feb;220(2):179-85 PubMed


Hansmann F, Prongproa K, Ulrich R, Sun Y, Hernder V, Kreutzer M, Baumgärtner W, Wewetzer K (2012):
Highly malignant behavior of a murine oligodendrocyte precursor cell line following transplantation into the demyelinated and non-demyelinated central nervous system
Cell Transplant 21(6):1161-75 PubMed


Imbschweiler I, Seehusen F, Peck CT, Omar M, Baumgärtner W, Wewetzer K (2012):
Increased p75 neurotrophin receptor expression in the canine distemper virus model of multiple sclerosis identifies aldynoglial schwann cells that emerge in response to axonal damage.
Glia 60(3):358-71 PubMed


Jung K, Schlenz H, Krasteva G, Mühlfeld C (2012):
Alveolar epithelial type II cells and their microenvironment in the caveolin-1-deficient mouse
Anat Rec 295(2):196-200 PubMed


Karagianni A, Mühlfeld C, Bode-Erdmann S, Vöhringer M, Sechtem U (2012):
Primary cardiac lymphoma causing coronary vasospasm.
Eur Heart J Cardiovasc Imaging 13(9):775 PubMed


Kellner M, Heidrich M, Beigel R, Lorbeer RA, Knudsen L, Ripken T, Heisterkamp A, Meyer H, Kühnel MP, Ochs M (2012):
Imaging of the mouse lung with scanning laser optical tomography (SLOT).
J Appl Physiol 113:975-983 PubMed


Knudsen L, Boxler L, Mühlfeld C, Schaefer IM, Becker L, Bussinger C, von Stietencron I, Madershahian N, Richter J, Wahlers T, Wittwer T, Ochs M (2012):
Lung preservation in experimental ischemia/reperfusion injury and lung transplantation: a comparison of natural and synthetic surfactants
J Heart Lung Transplant 31:85-93 PubMed


Leuenberger A, Gazdhar A, Herrmann G, Ochs M, Geiser T, Knudsen L (2012):
Cell-specific expression of human HGF by alveolar type II cells induces remodeling of septal wall tissue in the lung: a morphometric study.
J Appl Physiol 113:799-807 PubMed


Mühlfeld C, Poland C, Duffin R, Brandenberger C, Rothen-Rutishauser B, Gehr P, Donaldson K (2012):
Differential effects of long and short carbon nanotubes on the gas-exchange region of the mouse lung
Nanotoxicology 6:867-79 PubMed


Ochs M, Mühlfeld C, Schmiedl A (2012):
Präparierkurs. Grundlage ärztlichen Handelns.
Dt Ärztebl 109(43):A2126-A2127


Ochs M, O´Brodovich H (2012):
The structural and physiologic basis of respiratory disease.
In: Kendig and Chernick´s disorders of the respiratory tract in children, 8th ed. (Wilmott RW, Boat TF, Bush A, Chernick V, Deterding RR, Ratjen F, eds.) Elsevier, Philadelphia: 35-74


Patra C, Talukdar S, Novoyatleva T, Velagala SR, Mühlfeld C, Kundu SC, Engel FB (2012):
Silk fibroin from Antheraea mylitta: a novel biomaterial for cardiac tissue engineering
Biomaterials 33(9):2673-2680 PubMed


Penna V, Stark GB, Wewetzer K, Radtke C, Lang EM (2012):
Comparison of Schwann Cells and Olfactory Ensheathing Cells for Peripheral Nerve Gap Bridging.
Cells Tissues Organs 196(6):534-42 PubMed


Penna V, Wewetzer K, Munder B, Stark GB, Lang EM (2012):
The long-term functional recovery of repair of sciatic nerve transection with biogenic conduits.
Microsurgery 32(5):377-82 PubMed


Schumacher F, Engst W, Monien B, Florian S, Schnapper A, Steinhauser L, Albert K, Frank H, Seidel A, Glatt H-R (2012):
Detection of DNA adducts originating from 1-methoxy-3-indolylmethyl glucosinolate using isotope-dilution UPLC-ESI-MS/MS.
Anal Chem 84, 6256-6262 PubMed


Solomon PA, Gehr P, Bennett DH, Phalen RF, Mendez LB, Rothen-Rutishauser B, Clift M, Brandenberger C, Mühlfeld C (2012):
Macroscopic to microscopic scale of particle dosimetry: From source to fate in the body.
Air Qual Atmos Health 5(2): 169-187.


Sommer T, Buettner M, Bruns F, Breves G, Hadamitzky C, Pabst R (2012):
Improved regeneration of autologous transplanted lymph node fragments by VEGF-C treatment.
Anat Rec 295(5):786-91 PubMed


Steinwede K, Maus R, Bohling J, Voedisch S, Braun A, Ochs M, Schmiedl A, Länger F, Gauthier F, Roes J, Welte T, Bange FC, Niederweis M, Bühling F, Maus UA. (2012):
Cathepsin G and Neutrophil Elastase Contribute to Lung-Protective Immunity against Mycobacterial Infections in Mice
J Immunol. 188(9): 4476-4487, DOI: 10.4049/jimmunol.1103346


Timpel M, Wanderka N, Grothausmann R, Banhart J (2012)
Distribution of Fe-rich phases in eutectic grains of Sr-modified Al-10wt% Si-0.1wt% Fe casting alloy
Journal of Alloys and Compounds, 2012, 558, 18-25, DOI: 10.1016/j.jallcom.2012.12.009


Vasilescu DM, Gao Z, Saha PK, Yin L, Wang G, Haefeli-Bleuer B, Ochs M, Weibel ER, Hoffman EA (2012):
Assessment of morphometry of pulmonary acini in mouse lungs by non-destructive imaging using multi-scale micro-computed tomography.
Proc Natl Acad Sci USA 109:17105-17110 PubMed


Vasilescu DM, Knudsen L, Ochs M, Weibel ER, Hoffman EA (2012):
Optimized murine lung preparation for detailed structural evaluation via micro-computed tomography
J Appl Physiol. 112(1):159-66 PubMed


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Bartels H, Fazekas U, Youson JH, Potter IC (2011):
Changes in the cellular composition of the gill epithelium during the life cycle of a nonparasitic lamprey. Functional and evolutionary implications
Can J Zool 89: 538-545 Abstract

Buettner M, Bode U (2011):
Lymph node transplantation and its immunological significance in animal models
Clin Dev Immunol 353510 PubMed

Buettner M, Bode U (2011):
Stromal cells directly mediate the re-establishment of the lymph node compartments after transplantation by CXCR5 and CCL19/21 signalling
Immunology 133:257-69 PubMed

Buettner M, Pabst R, Bode U (2011):
Lymph node stromal cells strongly influence immune response suppression
Eur J Immunol 41: 624-633 PubMed

Brandes G, Khayami M, Peck CT, Baumgärtner W, Bugday H, Wewetzer K (2011):
Cell surface expression of 27C7 by neonatal rat olfactory ensheathing cells in situ and in vitro is independent of axonal contact
Histochem Cell Biol 135:397-408 PubMed

Djafarzadeh S, Vuda M, Takala J, Ochs M, Jakob SM (2011):
Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes
Mitochondrion 11:83-88 PubMed

Heine J, Schmiedl A, Cebotari S, Karck M, Mertsching H, Haverich A, Kallenbach K (2011):
Tissue engineering human small-caliber autologous vessels using a xenogenous decellularized connective tissue matrix approach: preclinical comparative biomechanical studies
Artif Organs 35:930-40 PubMed

Heine J, Schmiedl A, Cebotari S, Mertsching H, Karck M, Haverich A, Kallenbach K (2011):
Preclinical assessment of a tissue-engineered vasomotive human small-calibered vessel based on a decellularized xenogenic matrix: histological and functional characterization
Tissue Eng Part A17:1253-1261 PubMed

Hornickel IN, Kacza J, Schnapper A, Beyerbach M, Schoennagel B, Seeger J, Meyer W (2011):
Demonstration of substances of innate immunity in the esophagus epithelium of domesticated mammals. Part I − Methods and evaluation of comparative fixation
Acta Histochem 113: 163-174 PubMed

Hornickel IN, Kacza J, Schnapper A, Beyerbach M, Schoennagel B, Seeger J, Meyer W (2011):
Demonstration of substances of innate immunity in the esophagus epithelium of domesticated mammals. Part II − Defence mechanisms, including species comparison
Acta Histochem 113: 175-188 PubMed

Knudsen L, Ochs M (2011):
Microscopy-based quantitative analysis of lung structure: application in diagnosis
Expert Opin Med Diag 5:319-331 Abstract

Knudsen L, Waizy H, Fehrenbach H, Richter J, Wahlers T, Wittwer T, Ochs M (2011):
Ultrastructural changes of the intracellular surfactant pool in a rat model of lung transplantation-related events
Respir Res 12:79:1-10 PubMed

Krasteva G, Canning B, Hartmann P, Veres T, Papadakis T, Mühlfeld C, Schliecker K, Tallini YN, Braun A, Hackstein H, Baal N, Weihe E, Schutz B, Kotlikoff MI, Ibanez-Tallon I, Kummer W (2011):
Cholinergic chemosensory cells in the trachea regulate breathing
Proc Natl Acad Sci 108 (23): 9478-9483 PubMed

Küper C, Bartels H, Beck FX, Neuhofer W (2011):
Cyclooxygenase-2-dependant phosphorylation of the pro-apoptotic protein Bad inhibits tonicity-induced apoptosis in ernal medullary cells
Kidney Int 80: 2291-2300 PubMed

Li L, Mühlfeld C, Niemann B, Pan R, Li R, Hilfiker-Kleiner D, Chen Y, Rohrbach S (2011):
Mitochondrial biogenesis and PGC-1α deacetylation by chronic treadmill exercise: Differential response in cardiac and skeletal muscle
Basic Res Cardiol 106(6):1221-34 PubMed

Mühlfeld C, Das SK, Heinzel FR, Schmidt A, Post, H, Schauer S, Papadakis T, Kummer W, Hoefler G (2011):
Cancer induces cardiomyocyte remodeling and hypoinnervation in the left ventricle of the mouse heart
PLoS One 6 (5): e20424. doi: 10.1371/journal.pone.0020424 PubMed

Müller HC, Hocke AC, Hellwig K, Gutbier B, Peters H, Schönrock SM, Tschernig T, Schmiedl A, Hippenstiel S, N'Guessan PD, Rosseau S, Suttorp N, Witzenrath M (2011):
The Sphingosine-1 Phosphate receptor agonist FTY720 dose dependently affected endothelial integrity in vitro and aggravated ventilator-induced lung injury in mice
Pulm Pharmacol Ther 24:377-385 PubMed

Omar M, Bock P, Kreutzer R, Ziege S, Imbschweiler I, Hansmann F, Peck CT, Baumgärtner W, Wewetzer K (2011):
Defining the morphological phenotype: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) is a novel marker for in situ detection of canine but not rat olfactory ensheathing cells
Cell Tissue Res 344:391-405 PubMed

Patra C, Diehl F, Ferrazi F, van Amerongen MJ, Novoytleva T, Schaefer L, Mühlfeld C, Jungblut B, Engel FB (2011):
Nephronectin regulates via BMP4-HAS2 signaling the differentiation of the atrio-ventricular canal in zebrafish
Development 138: 4499-4509 PubMed

Radtke C, Wewetzer K, Reimers K, Vogt PM (2011):
Transplantation of olfactory ensheathing cells as adjunct cell therapy for peripheral nerve injury
Cell Transplant 20:145-152 PubMed

Schmiedl A, Behrens J, Zscheppang K, Purevdorj E, von Mayersbach D, Liese A, Dammann CE (2011):
Lipopolysaccharide-induced injury is more pronounced in fetal transgenic ErbB4-deleted lungs
Am J Physiol Lung Cell Mol Physiol 30:L490-499 PubMed

Spitzbarth I, Bock P, Haist V, Stein VM, Tipold A, Wewetzer K, Baumgärtner W, Beineke A (2011):
Prominent microglial activation in the early proinflammatory immune response in naturally occurring canine spinal cord injury
J Neuropathol Exp Neurol 70:703-714 PubMed

Stephan M, Radicke A, Leutloff S, Schmiedl A, Pabst R, von Hörsten S, Dettmer S, Lotz J, Nave H (2011):
Dipeptidyl peptidase IV (DPP4)-deficiency attenuates diet-induced obesity in rats: possible implications for the hypothalamic neuropeptidergic system
Behav Brain Res 216:712-718 PubMed

Suana A, Tuffin G, Frey BM, Knudsen L, Mühlfeld C, Roedder S, Marti HP (2011):
Single application of low dose MMF-OX7-Immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis
J Pharmacol Exp Therap 337 (2): 411-422 PubMed

Tasic T, Bäumer W, Schmiedl A, Schwichtenhövel F, Pabst R, Raap U, von Hörsten S, Stephan M (2011):
Dipeptidyl peptidase IV (DPP4) deficiency increases Th1-driven allergic contact dermatitis
Clin Exp Allergy 41:1098-1107 PubMed

Techangamsuwan S, Orlando EA, Imbschweiler I, Gerhauser I, Wewetzer K, Baumgärtner W (2011):
Cell-cell interaction appears to be a pivotal factor for susceptibility of adult canine Schwann cell-like brain glia to canine distemper virus infection in vitro
Thai J Vet Med. 2011 41:213-225.

Trachsel S, Purkabiri K, Loup O, Jenni H, Eberle B, Ochs M, Kadner A (2011):
High-quality lung fixation by controlled closed loop perfusion for stereological analysis in a large animal model
J Surg Res 166:97-102 PubMed

Volkmann J, Müller D, Feuerstacke C, Kliesch S, Bergmann M, Mühlfeld C, Middendorff R (2011):
Disturbed spermatogenesis associated with thickened lamina propria of seminiferous tubules is not caused by dedifferentiation of myofibroblasts
Hum Reprod 26 (6): 1450-1461 PubMed

Wewetzer K, Radtke C, Kocsis J, Baumgärtner W (2011):
Species-specific control of cellular proliferation and the impact of large animal models for the use of olfactory ensheathing cells and Schwann cells in spinal cord repair
Exp Neurol 229:80-87 PubMed

Zscheppang K, Dörk T, Schmiedl A, Jones FE, Dammann CE (2011):
Neuregulin receptor ErbB4 functions as a transcriptional cofactor for the expression of surfactant protein B in the fetal lung
Am J Respir Cell Mol Biol 45:761-767 PubMed

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Buettner M, Pabst R, Bode U (2010):
Stromal cell heterogeneity in lymphoid organs
Trends Immunol 31: 80-86 PubMed

Hahn A, Thiessen N, Pabst R, Buettner M, Bode U (2010):
Mesenteric lymph nodes are not required for an intestinal immunoglobulin A response to oral cholera toxin
Immunology 129: 427-436 PubMed

Hsia CCW, Hyde DM, Ochs M, Weibel ER (2010):
An official research policy statement of the American Thoracic Society / European Respiratory Society: Standards for quantitative assessment of lung structure
Am J Respir Crit Care Med 181:394-418 PubMed

Knudsen L, Weibel ER, Gundersen HJG, Weinstein FV, Ochs M (2010):
Assessment of airspace size characteristics by intercept (chord) measurement: an accurate and efficient stereological approach
J Appl Physiol 108:412-421 PubMed

Mühlfeld C, Becker L, Bussinger C, Vollroth M, Nagib R, Schaefer I, Knudsen L, Richter J, Madershahian N, Wahlers T, Wittwer T, Ochs M (2010):
Exogenous surfactant in ischemia/reperfusion: effects on endogenous surfactant pools
J Heart Lung Transplant 29:327-334 PubMed

Mühlfeld C, Weibel ER, Hahn U, Kummer W, Nyengaard JR, Ochs M (2010):
Is length an appropriate estimator to characterize pulmonary alveolar capillaries? A critical evaluation in the human lung
Anat Rec 293:1270-1275 PubMed

Ochs M (2010):
The closer we look the more we see? Quantitative microscopic analysis of the pulmonary surfactant system
Cell Physiol Biochem 25:27-40 PubMed

Singer T, Brand V, Moehrlen U, Fehrenbach H, Purkabiri K, Ott SR, Stammberger U, Ochs M, Hamacher J (2010):
Left-sided mouse intubation: description and evaluation
Exp Lung Res 36:25-30 PubMed

Vanhecke D, Herrmann G, Graber W, Hillmann-Marti T, Mühlfeld C, Studer D, Ochs M (2010):
Lamellar body ultrastructure revisited: high-pressure freezing and cryo-electron microscopy of vitreous sections
Histochem Cell Biol 134:319-326 PubMed

Wirkes A, Jung K, Ochs M, Mühlfeld C (2010):
Allometry of the mammalian intracellular pulmonary surfactant system
J Appl Physiol 109:1662-1669 PubMed

Wulfsohn D, Knust J, Ochs M, Nyengaard JR, Gundersen HJG (2010):
Stereological estimation of the total number of ventilatory units in mice lungs
J Microsc 238:75-89 PubMed

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Knudsen L, Wucherpfennig K, Mackay R, Townsend P, Deb R, Mühlfeld C, Richter J, Hawgood S, Reid K, Clark H, Ochs M (2009):

A recombinant fragment of human surfactant protein D lacking the short collagen-like stalk fails to correct morphological alterations in lungs of SP-D deficient mice

Anat Rec 292:183-189 PubMed

Knust J, Ochs M, Gundersen HJG, Nyengaard JR (2009):
Stereological estimates of alveolar number and size and capillary length and surface area in mice lungs

Anat Rec 292:113-122 PubMed

Mayhew TM, Mühlfeld C, Vanhecke D, Ochs M (2009):

A review of recent methods for efficiently quantifying immunogold and other nanoparticles using TEM sections through cells, tissues and organs

Ann Anat 191:153-170 PubMed

Mühlfeld C, Schaefer IM, Becker L, Bussinger C, Vollroth M, Bosch A, Nagib R, Madershahian N, Richter J, Wahlers T, Wittwer T, Ochs M (2009):

Pre-ischaemic exogenous surfactant reduces pulmonary injury in rat ischaemia/reperfusion

Eur Respir J 33:625-633 PubMed

Mühlfeld C, Ochs M (2009):

Functional aspects of lung structure as related to interaction with particles
In: Particle-lung interactions, 2nd ed.
(Gehr P, Mühlfeld C, Blank F, Rothen-Rutishauser B, eds.)
Lung biology in health and disease, vol. 241

Informa Healthcare, New York: 1-16

Ochs M, Burri PH, Gil J, Weibel ER (2009):
Ultrastructure and morphometry of the human lung
In: General thoracic surgery, 7th ed.
(Shields TW, LoCicero J, Reed CE, Feins RH, eds.)
Lippincott Williams & Wilkins, Philadelphia: 39-59

Regueira T, Lepper PM, Brandt S, Ochs M, Vuda M, Takala J, Jakob SM, Djafarzadeh S (2009):

HIF-1α induction by tumor necrosis factor-α, but not by toll-like receptor agonists, modulates cellular respiration in cultured human hepatocytes
Liver Int 29:1582-1592 PubMed

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Dreyer N, Mühlfeld C, Fehrenbach A, Pech T, von Berg S, Nagib R, Richter J, Wittwer T, Wahlers T, Ochs M (2008):
Exogenous surfactant application in a rat lung ischemia reperfusion injury model: effects on edema formation and alveolar type II cells
Respir Res 9:5:1-10 PubMed

Goering W, Adham IM, Pasche B, Maenner J, Ochs M, Engel W, Zoll B (2008):
Impairment of gastric acid secretion and increase of embryonic lethality in Foxq1-deficient mice
Cytogenet Genome Res 121:88-95 PubMed

Mühlfeld C, Rothen-Rutishauser B, Blank F, Vanhecke D, Ochs M, Gehr P (2008):
Interactions of inhaled nanoparticles with pulmonary structures and cellular responses
Am J Physiol (Lung Cell Mol Physiol) 294:L817-L829 PubMed

Ochs M, Weibel ER (2008):
Functional design of the human lung for gas exchange
In: Fishman´s pulmonary diseases and disorders, 4th ed.
(Fishman AP, Elias JA, Fishman JA, Grippi MA, Senior RM, Pack AI, eds.)
McGraw-Hill, New York:23-69

Regamey N, Ochs M, Hilliard TN, Mühlfeld C, Cornish N, Fleming L, Saglani S, Alton EWFW, Bush A, Jeffery PK, Davies JC (2008):
Increased airway smooth muscle mass in children with asthma, cystic fibrosis and bronchiectasis
Am J Respir Crit Care Med 177:837-843 PubMed

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Bräuer L, Kindler C, Jäger K, Sel S, Nölle B, Pleyer U, Ochs M, Paulsen F (2007):
Detection of surfactant proteins A and D in human tear fluid and the human lacrimal system
Invest Ophthalmol Vis Sci 48:3945-3953 PubMed

Knudsen L, Ochs M, MacKay R, Townsend P, Deb R, Mühlfeld C, Richter J, Gilbert F, Hawgood S, Reid K, Clark H (2007):
Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice
Respir Res 8:70:1-12 PubMed

Makanya AN, Hlushchuk R, Baum O, Velinov N, Ochs M, Djonov V (2007):
Microvascular endowment in the developing chicken embryo lung
Am J Physiol (Lung Cell Mol Physiol) 292:L1136-L1146 PubMed

Mühlfeld C, Müller K, Pallesen LP, Sandhaus T, Madershahian N, Richter J, Wahlers T, Wittwer T, Ochs M (2007):
Impact of preservation solution on the extent of blood-air barrier damage and edema formation in experimental lung transplantation
Anat Rec 290:491-500 PubMed

Mühlfeld C, Rothen-Rutishauser B, Vanhecke D, Blank F, Gehr P, Ochs M (2007):
Visualization and quantitative analysis of nanoparticles in the respiratory system by transmission electron microscopy
Part Fibre Toxicol 4:11:1-17 PubMed

Rüdiger M, Wendt S, Köthe L, Burkhardt W, Wauer RR, Rüstow B, Ochs M (2007):
Alterations of alveolar type II cells and intraalveolar surfactant after bronchoalveolar lavage and perfluorocarbon ventilation. An electron microscopical and stereological study in the rat lung
Respir Res 8:40:1-9 PubMed

Spinelli Oliveira E, Hancock JT, Hermes-Lima M, Isola DA, Ochs M, Yu J, Filho DW (2007):
Implications of dealing with airborne substances and reactive oxygen species: what mammalian lungs, animals and plants have to say?
Integr Comp Biol 47:578-591 Abstract

Vanhecke D, Studer D, Ochs M (2007):
Stereology meets electron tomography: towards quantitative 3D electron microscopy
J Struct Biol 159:443-450 PubMed

Weibel ER, Hsia CCW, Ochs M (2007):
How much is there really? Why stereology is essential in lung morphometry
J Appl Physiol 102:459-467 PubMed

Wittwer T, Franke UF, Sandhaus T, Thiene M, Groetzner J, Strauch JT, Wippermann J, Ochs M, Mühlfeld C (2007):
Preischemic Iloprost application for improvement of graft preservation: which route is superior in experimental pig lung transplantation: inhaled or intravenous?
Transplant Proc 39:1345-1349 PubMed

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Brasch F, Schimanski S, Mühlfeld C, Barlage S, Langmann T, Aslanidis C, Boettcher A, Dada A, Schroten H, Mildenberger E, Prueter E, Ballmann M, Ochs M, Johnen G, Griese M, Schmitz G (2006):
Alteration of the pulmonary surfactant system in full-term infants with hereditary ABCA3 deficiency
Am J Respir Crit Care Med 174:571-580 PubMed

Ochs M (2006):
A brief update on lung stereology
J Microsc 222:188-200 PubMed

Ochs M (2006):
Stereological analysis of acute lung injury
Eur Respir Rev 15:115-121 Abstract

Ochs M, Schüttler M, Stichtenoth G, Herting E (2006):
Morphological alterations of exogenous surfactant inhibited by meconium can be prevented by dextran
Respir Res 7:86:1-8 PubMed

Wittwer T, Franke UFW, Sandhaus T, Groetzner J, Strauch JT, Wippermann J, Ochs M, Mühlfeld C, Börner A, Streck S, Wahlers T (2006):
Endobronchial donor pre-treatment with Ventavis: Is a second administration during reperfusion beneficial to optimize post-ischemic function of non-heart beating donor lungs?
J Surg Res 136:136-142 PubMed

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Fehrenbach H, Tews S, Fehrenbach A, Ochs M, Wittwer T, Wahlers T, Richter J (2005):
Improved lung preservation relates to an increase in tubular myelin-associated surfactant protein A
Respir Res 6:60:1-12 PubMed

Jung A, Allen L, Nyengaard JR, Gundersen HJG, Richter J, Hawgood S, Ochs M (2005):
Design-based stereological analysis of the lung parenchymal architecture and alveolar type II cells in surfactant protein A and D double deficient mice
Anat Rec 286:885-890 PubMed

Schmiedl A, Ochs M, Mühlfeld C, Johnen G, Brasch F (2005):
Distribution of surfactant proteins in the lung of newborn, 14 days old and adult rats. An immunoelectron microscopic and stereological study
Histochem Cell Biol 124:465-476 PubMed

Stevens PA, Pettenazzo A, Brasch F, Mulugeta S, Baritussio A, Ochs M, Morrison L, Russo SJ, Beers MF (2005):
Non-specific interstitial pneumonia, lipoproteinosis, and abnormal proprotein trafficking resulting from a spontaneous mutation in the surfactant protein C gene
Pediatr Res 57:89-98 PubMed

Wittwer T, Franke UFW, Fehrenbach A, Ochs M, Sandhaus T, Schuette A, Richter S, Dreyer N, Knudsen L, Schubert H, Richter J, Wahlers T (2005):
Donor pretreatment using the aerosolized prostacyclin analogue Iloprost optimizes post-ischemic function of non-heart beating donor lungs
J Heart Lung Transplant 24:371-378 PubMed

Wittwer T, Franke UFW, Fehrenbach A, Ochs M, Sandhaus T, Schuette A, Richter S, Dreyer N, Knudsen L, Müller T, Schubert H, Richter J, Wahlers T (2005):
Experimental lung transplantation: impact of preservation solution and route of delivery
J Heart Lung Transplant 24:1081-1090 PubMed

Wittwer T, Franke UFW, Ochs M, Sandhaus T, Schuette A, Richter S, Dreyer N, Knudsen L, Müller T, Schubert H, Richter J, Wahlers T (2005):
Inhalative pre-treatment of donor lungs using the aerosolized prostacyclin analogue Iloprost ameliorates reperfusion injury
J Heart Lung Transplant 24:1673-1679 PubMed

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Ausgewählte Publikationen vor 2005:

Brasch F, Johnen G, Winn-Brasch A, Guttentag S, Schmiedl A, Kapp N, Suzuki Y, Müller KM, Richter J, Hawgood S, Ochs M (2004):
Surfactant protein B in type II pneumocytes and intraalveolar surfactant forms of human lungs
Am J Respir Cell Mol Biol 30:449-458 PubMed

Brasch F, Griese M, Tredano M, Johnen G, Ochs M, Rieger C, Mulugeta S, Müller KM, Bahuau M, Beers MF (2004):
Interstitial lung disease in a baby with a de novo mutation in the SFTPC gene
Eur Respir J 24:30-39 PubMed

Brasch F, Birzele J, Ochs M, Guttentag S, Schoch OD, Böhler A, Beers MF, Müller KM Hawgood S, Johnen G (2004):
Surfactant proteins in pulmonary alveolar proteinosis in adults
Eur Respir J 24:426-435 PubMed

Ochs M, Nyengaard JR, Jung A, Knudsen L, Voigt M, Wahlers T, Richter J, Gundersen HJG (2004):
The number of alveoli in the human lung
Am J Respir Crit Care Med 169:120-124 PubMed

Ochs M, Knudsen L, Allen L, Stumbaugh A, Levitt S, Nyengaard JR, Hawgood S (2004):
GM-CSF mediates alveolar epithelial type II cell changes, but not emphysema-like pathology, in SP-D deficient mice
Am J Physiol (Lung Cell Mol Physiol) 287:L1333-L1341 PubMed

Ochs M, Fehrenbach H, Richter J (2004):
Occurence of lipid bodies in canine type II pneumocytes during hypothermic lung ischemia
Anat Rec 277:287-297 PubMed

Wittwer T, Franke UFW, Fehrenbach A, Ochs M, Sandhaus T, Dreyer N, Richter J, Wahlers T (2004):
Innovative pulmonary preservation of non-heart-beating donor grafts in experimental lung transplantation
Eur J Cardio-Thorac Surg 26:144-150 PubMed

Brasch F, Ochs M, Kähne T, Guttentag S, Schauer-Vukasinovic V, Derrick M, Johnen G, Kapp N, Müller KM, Richter J, Giller T, Hawgood S, Bühling F (2003):
Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II-pneumocytes of the human lung
J Biol Chem 278:49006-49014 PubMed

Rüdiger M, Wissel H, Ochs M, Burkhardt W, Proquitté H, Wauer RR, Stevens P, Rüstow B (2003):
Perfluorocarbons are taken up by type II pneumocytes and influence its lipid synthesis and secretion
Crit Care Med 31:1190-1196 PubMed

Schmiedl A, Hoymann HG, Ochs M, Menker A, Fehrenbach A, Krug N, Tschernig T, Hohlfeld JM (2003):
Increase of inactive intraalveolar surfactant subtypes in lungs of asthmatic Brown Norway rats
Virchows Arch 442:56-65 PubMed

Hawgood S, Ochs M, Jung A, Akiyama J, Allen L, Brown C, Edmondson J, Levitt S, Carlson E, Gillespie AM, Villar A, Epstein CJ, Poulain FR (2002):
Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema
Am J Physiol (Lung Cell Mol Physiol) 283:L1002-L1010 PubMed

Ochs M, Johnen G, Müller KM, Wahlers T, Hawgood S, Richter J, Brasch F (2002):
Intracellular and intraalveolar localization of surfactant protein A (SP-A) in the parenchymal region of the human lung
Am J Respir Cell Mol Biol 26:91-98 PubMed

Ochs M, Fehrenbach H, Richter J (2001):
Ultrastructure of canine type II pneumocytes during hypothermic ischemia of the lung – a study by means of conventional and energy filtering transmission electron microscopy and stereology
Anat Rec 263:118-126 PubMed

Ochs M (2001):
Pulmonary surfactant preservation in experimental and clinical lung transplantation
In: Recent research developments in respiratory and critical care medicine (Pandalai SG, ed.)
Research Signpost, Trivandrum:59-81

Fehrenbach A, Ochs M, Wahlers T, Wittwer T, Schmiedl A, Elki S, Meyer D, Richter J, Fehrenbach H (2000):
Beneficial effect of lung preservation is related to ultrastructural integrity of tubular myelin after experimental ischemia and reperfusion
Am J Respir Crit Care Med 161:2058-2065 PubMed

Ochs M, Fehrenbach H, Nenadic I, Bando T, Fehrenbach A, Schepelmann D, Albes JM, Wahlers T, Richter J (2000):
Preservation of intraalveolar surfactant in a rat lung ischaemia/reperfusion injury model
Eur Respir J 15:526-531 PubMed

Fehrenbach A, Ochs M, Wittwer T, Cornelius J, Fehrenbach H, Wahlers T, Richter J (1999):
Stereological estimation of the volume weighted mean volume of alveoli and acinar pathways in the rat lung to characterise alterations after ischaemia/reperfusion
J Anat 194:127-135 PubMed

Ochs M, Nenadic I, Fehrenbach A, Albes JM, Wahlers T, Richter J, Fehrenbach H (1999):
Ultrastructural alterations in intraalveolar surfactant subtypes after experimental ischemia and reperfusion
Am J Respir Crit Care Med 160:718-724 PubMed

Wittwer T, Wahlers T, Fehrenbach A, Cornelius JF, Elki S, Ochs M, Fehrenbach H, Albes J, Haverich A, Richter J (1999):
Combined use of prostacyclin and higher perfusate temperatures further enhances the superior lung preservation by Celsior solution in the isolated rat lung
J Heart Lung Transplant 18:684-692 PubMed

Fehrenbach H, Wahlers T, Ochs M, Brasch F, Schmiedl A, Hirt SW, Haverich A, Richter J (1998):
Ultrastructural pathology of the alveolar type II pneumocytes of human donor lungs. Electron microscopy, stereology, and microanalysis
Virchows Arch 432:229-239 PubMed

Fehrenbach H, Ochs M (1998):
Studying lung ultrastructure
In: Methods in pulmonary research (Uhlig S, Taylor AE, eds.)
Birkhäuser, Basel:429-454

Stolte N, Fehrenbach H, Ochs M, Schmiedl A, Hirt SW, Wahlers T, Richter J (1996):
Effects of ischaemia and preservation on the ultrastructure of the bronchiolar epithelium. A quantitative electron microscopic study of human and canine lungs
Virchows Arch 429:109-118 PubMed

Fehrenbach H, Ochs M, Richter J (1995):
Energy-filtering TEM in the fine-structural study of the mammalian lung
Microsc Anal 37:11-14

Ochs M, Fehrenbach H, Richter J (1994):
Electron spectroscopic imaging (ESI) and electron energy loss spectroscopy (EELS) of multilamellar bodies and multilamellar body-like structures in tannic acid-treated alveolar septal cells
J Histochem Cytochem 42:805-809 PubMed

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