Prof. Dr. Thomas Krey is Professor of Structural Virology located at the Institute of Virology, MHH in Hannover.
Our research is focused on structural studies in order to understand molecular mechanisms that are essential for various steps of the virus cycle.
We study mostly viruses that constitute a global public health and/or veterinary concern and use structural biology/biophysical methods with a special focus on X-ray crystallography. The structural knowledge gained from our experiments can be used for structure-based design of preventive or curative antiviral agents, i.e., this knowledge has a direct potential for translational medicine. Furthermore, structural studies are often performed in parallel on homologous proteins from related viruses, which provides crucial information about the evolutionary relationship between these viruses and allows the identification of conserved features and/or pathways, which often are the most promising drug targets.