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apl. Prof. Dr. Falk F. R. Büttner

Außerplanmäßiger Professor


Geb. J3, Ebene 04, Raum 1291 oder 1250

Telefon: +49(0)511-532-8245

Mobil: 0162-7037789

Fax: +49(0)511/532-8801


E-Mail: Buettner.Falk(at)




Research Interests


- Glycomics

- Proteomics

- Stem Cells

- Actinobacillus pleuropneumoniae

- Veterinary Vaccines



Group Members


Astrid Oberbeck, technician


Sarah Konze, Post Doc:

Project: Glycoproteomic and proteomic analysis of human induced pluripotent stem cells (iPSCs) during differentiation into cardiomyocytes.


Hanna Wolling, PhD student, programme “Regenerative Sciences


Karsten Cirksena, PhD student, programme “Regenerative Sciences


Charlotte Rossdam, PhD student







Behrens W, Schweinitzer T, McMurry JL, Loewen PC, Buettner FF, Menz S, Josenhans C. Localisation and protein-protein interactions of the Helicobacter pylori taxis sensor TlpD and their connection to metabolic functions. Sci Rep. 2016 Apr 5;6:23582. doi: 10.1038/srep23582.


Kempf H, Olmer R, Haase A, Franke A, Bolesani E, Schwanke K, Robles-Diaz D, Coffee M, Göhring G, Dräger G, Pötz O, Joos T, Martinez-Hackert E, Haverich A, Buettner FF, Martin U, Zweigerdt R. Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells. Nat Commun. 2016 Dec 9;7:13602. doi: 10.1038/ncomms13602.


Experimental Actinobacillus pleuropneumoniae challenge in swine: Comparison of computed tomographic and radiographic findings during disease.

Brauer C, Hennig-Pauka I, Hoeltig D, Buettner FF, Beyerbach M, Gasse H, Gerlach GF, Waldmann KH.

BMC Vet Res. 2012 Apr 30;8(1):47.


Molecular cloning of a xylosyltransferase that transfers the second xylose to O-glucosylated epidermal growth factor repeats of notch.

Sethi MK, Buettner FF, Ashikov A, Krylov VB, Takeuchi H, Nifantiev NE, Haltiwanger RS, Gerardy-Schahn R, Bakker H.

J Biol Chem. 2012 Jan 20;287(4):2739-48.


Proteomic and immunoproteomic characterization of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae.

Buettner FF, Konze SA, Maas A, Gerlach GF.

Proteome Sci. 2011 Apr 20;9(1):23.


Identification of glycosyltransferase 8 family members as xylosyltransferases acting on O-glucosylated notch epidermal growth factor repeats.

Sethi MK, Buettner FF, Krylov VB, Takeuchi H, Nifantiev NE, Haltiwanger RS, Gerardy-Schahn R, Bakker H.

J Biol Chem. 2010 Jan 15;285(3):1582-6.


Glycoprotein analysis of porcine bronchoalveolar lavage fluid reveals potential biomarkers corresponding to resistance to Actinobacillus pleuropneumoniae infection.

Kahlisch D, Buettner FF, Naim HY, Gerlach GF; FUGATO-consortium IRAS.

Vet Res. 2009 Nov-Dec;40(6):60.


Analysis of the immunoproteome of Mycoplasma mycoides subsp. mycoides small colony type reveals immunogenic homologues to other known virulence traits in related Mycoplasma species.

Jores J, Meens J, Buettner FF, Linz B, Naessens J, Gerlach GF.

Vet Immunol Immunopathol. 2009 Oct 15;131(3-4):238-45.


Analysis of the Actinobacillus pleuropneumoniae HlyX (FNR) regulon and identification of iron-regulated protein B as an essential virulence factor.

Buettner FF, Bendalla IM, Bossé JT, Meens J, Nash JH, Härtig E, Langford PR, Gerlach GF.

Proteomics. 2009 May;9(9):2383-98.


Analysis of the Actinobacillus pleuropneumoniae ArcA regulon identifies fumarate reductase as a determinant of virulence.

Buettner FF, Bendallah IM, Bosse JT, Dreckmann K, Nash JH, Langford PR, Gerlach GF.

Infect Immun. 2008 Jun;76(6):2284-95.


An Actinobacillus pleuropneumoniae arcA deletion mutant is attenuated and deficient in biofilm formation.

Buettner FF, Maas A, Gerlach GF.

Vet Microbiol. 2008 Feb 5;127(1-2):106-15.


Selective capture of transcribed sequences (SCOTS) of Actinobacillus pleuropneumoniae in the chronic stage of disease reveals an HlyX-regulated autotransporter protein.

Baltes N, Buettner FF, Gerlach GF.

Vet Microbiol. 2007 Jul 20;123(1-3):110-21.


Deletion of the anaerobic regulator HlyX causes reduced colonization and persistence of Actinobacillus pleuropneumoniae in the porcine respiratory tract.

Baltes N, N'diaye M, Jacobsen ID, Maas A, Buettner FF, Gerlach GF.

Infect Immun. 2005 Aug;73(8):4614-9.