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2017

 

Buck A, Kayacelebi A A, Chobanyan-Jürgens K, Illsinger S, Bohnhorst B, Beckmann B, Hanff E, Das A M, Tsikas D, Lücke T

Comprehensive analysis of the L-arginine/L-homoarginine/nitric oxide pathway in preterm neonates: potential roles for homoarginine and asymmetric dimethylarginine in foetal growth.

Amino Acids 2017; 49(4):783-794
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Debez A, Belghith I, Pich A, Taamalli W, Abdelly C, Braun H P

High salinity impacts germination of the halophyte Cakile maritima but primes seeds for rapid germination upon stress release.

Physiol. Plant. 2017, ppl.12679-
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Erdmann J, Junemann J, Schröder A, Just I, Gerhard R, Pich A

Glucosyltransferase-dependent and -independent effects of TcdB on the proteome of HEp-2 cells.

Proteomics 2017; 17(15-16):1600435-

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Fischer V, Just I

Qualitätssicherung in Prüfungen am Beispiel von 10 Jahren e-Prüfungen an der MHH.

Qualität in der Wissenschaft (QiW) 2017; 11(2):60-64
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Günes D N, Kayacelebi A A, Hanff E, Lundgren J, Redfors B, Tsikas D

Metabolism and distribution of pharmacological homoarginine in plasma and main organs of the anesthetized rat.

Amino Acids 2017; 49(12):2033-2044
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Haghikia A, Yanchev G R, Kayacelebi A A, Hanff E, Bledau N, Widera C, Sonnenschein K, Haghikia A, Weissenborn K, Bauersachs J, Bavendiek U, Tsikas D

The role of L-arginine/L-homoarginine/nitric oxide pathway for aortic distensibility and intima-media thickness in stroke patients.

Amino Acids 2017; 49(6):1111-1121
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Hoepfner J, Kleinsorge M, Papp O, Alfken S, Heiringhoff R, Pich A, Sauer V, Zibert A, Göhring G, Schmidt H, Sgodda M, Cantz T

In vitro modelling of familial amyloidotic polyneuropathy allows quantitative detection of transthyretin amyloid fibril-like structures in hepatic derivatives of patient-specific induced pluripotent stem cells.

Biol.Chem. 2017; 398(8):939-954
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Junemann J, Lämmerhirt C M, Polten F, Just I, Gerhard R, Genth H, Pich A

Quantification of small GTPase glucosylation by clostridial glucosylating toxins using multiplexed MRM analysis.

Proteomics 2017; 17(9):1700016-
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Kayacelebi A A, Minovic I, Hanff E, Frenay A S, de Borst M H,  Feelisch M, van Goor H, Bakker S J L, Tsikas D

Low plasma homoarginine concentration is associated with high rates of all-cause mortality in renal transplant recipients.

Amino Acids 2017; 49(7):1193-1202
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Konze S A, Cajic S, Oberbeck A, Hennig R, Pich A, Rapp E, Buettner F F R

Quantitative Assessment of Sialo-Glycoproteins and N-Glycans during Cardiomyogenic Differentiation of Human Induced Pluripotent Stem Cells.

Chembiochem 2017; 18(13):1317-1331
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Konze S A, Werneburg S, Oberbeck A, Olmer R, Kempf H, Jara-Avaca M, Pich A, Zweigerdt R, Buettner F F

Proteomic Analysis of Human Pluripotent Stem Cell Cardiomyogenesis Revealed Altered Expression of Metabolic Enzymes and PDLIM5 Isoforms.

J. Proteome Res. 2017; 16(3):1133-1149
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Kukoc-Modun L, Tsikas D, Kraljevi T, Biocic M, Radi N

Kinetic Spectrophotometric Determination of N-Acetyl-L-cysteine Ethyl Ester (NACET) Generating Chromogenic Copper(I)Ln Complexes with Different Ligands.

Croat. Chem. Acta 2017; 90(2):263-271
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Lam K H, Qi R, Liu S, Kroh A, Yao G, Perry K, Rummel A, Jin R

The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein.

Toxicon 2017; DOI: 10.1016/j.toxicon.2017.10.012-
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Nkuipou-Kenfack E, Schanstra J  P, Bajwa S, Pejchinovski M, Vinel C, Dray C, Valet P, Bascands J  L, Vlahou A, Koeck T, Borries M, Busch H, Bechtel-Walz W, Huber T B, Rudolph K L, Pich A, Mischak H, Zürbig P

The use of urinary proteomics in the assessment of suitability of mouse models for ageing.

PLoS One 2017; 12(2):e0166875-
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Peck M W, Smith T J, Anniballi F, Austin J W, Bano L, Bradshaw M, Cuervo P, Cheng L W, Derman Y, Dorner B G, Fisher A, Hill K K, Kalb S R, Korkeala H, Lindström M, Lista F, Luquez C, Mazuet C, Pirazzini M, Popoff M R, Rossetto O, Rummel A, Sesardic D, Singh B R, Stringer S C

Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature.

Toxins (Basel) 2017; 9(1):DOI: 10.3390/toxins9010038-
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Reboll M R, Korf-Klingebiel M, Klede S, Polten F, Brinkmann E, Reimann I, Schonfeld H J, Bobadilla M, Faix J, Kensah G, Gruh I, Klintschar M, Gaestel M, Niessen H W, Pich A, Bauersachs J, Gogos J A, Wang Y, Wollert K C

EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) Is a Bone Marrow-Derived Angiogenic Growth Factor Promoting Tissue Repair After Myocardial Infarction.

Circulation 2017; 136(19):1809-1823
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Rohrbeck A, Höltje M, Adolf A, Oms E, Hagemann S, Ahnert-Hilger G, Just I

The Rho ADP-ribosylating C3 exoenzyme binds cells via an Arg-Gly-Asp motif.

J. Biol. Chem. 2017; 292(43):17668-17680
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Ruhe F, Olling A, Abromeit R, Rataj D, Grieschat M, Zeug A, Gerhard R, Alekov A

Overexpression of the Endosomal Anion/Proton Exchanger ClC-5 Increases Cell Susceptibility toward Clostridium difficile Toxins TcdA and TcdB.

Front. Cell. Infect. Microbiol. 2017; 7(67-
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Rummel A

Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.

Curr.Top.Microbiol.Immunol. 2016; DOI: 10.1007/82_2016_48-
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Schulze J, Kaiser O, Paasche G, Lamm H, Pich A, Hoffmann A, Lenarz T, Warnecke A

Effect of hyperbaric oxygen on BDNF-release and neuroprotection: Investigations with human mesenchymal stem cells and genetically modified NIH3T3 fibroblasts as putative cell therapeutics.

PLoS One 2017; 12(5):e0178182-
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Tsikas D

Combating atherosclerosis with heavy PUFAs: Deuteron not proton is the first.

Atherosclerosis 2017; 264:79-82
Editorial
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Tsikas D

The dilemma of oxidative stress personified by the disprosopus 8-iso-prostaglandin F2a and prostaglandin F2a.

J Controversies Biomed Res 2017; 3(1):11-15
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Tsikas D

Does oxidative stress change during orthotopic liver transplantation?

J Controversies Biomed Res 2017; 3(2):1-5
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Tsikas D

Does the Inhibitory Action of Asymmetric Dimethylarginine (ADMA) on the Endothelial Nitric Oxide Synthase Activity Explain Its Importance in the Cardiovascular System? The ADMA Paradox.

J Controversies Biomed Res 2017; 3(1):16-22
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Tsikas D

Letter to the Editor regarding "Identification of the oleic acid ethanolamide (OEA) isomer cis-vaccenic acid ethanolamide (VEA) as a highly abundant 18:1 fatty acid ethanolamide in blood plasma from rats and humans&quot.

Anal.Bioanal Chem. 2017; 409(9):2495-
Letter
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Tsikas D

Measuring NO production rate from l-arginine in MELAS by mass spectrometry-based approaches: GC-MS or LC-MS/MS?

Int.J.Cardiol. 2017; DOI: 10.1016/j.ijcard.2017.11.040-
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Tsikas D

Peroxynitrite-mediated 9,10-dihydroxylation of deuterium-labeled oleic acid in human hemolysate to threo- and erythro-dihydroxy-[9,10-2H2]stearic acid.

JSM Biochem Mol Biol 2017; 4(2):1027-
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Tsikas D

What we-authors, reviewers and editors of scientific work-can learn from the analytical history of biological 3-nitrotyrosine.

J.Chromatogr.B.Analyt Technol.Biomed.Life.Sci. 2017; 1058:68-72
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Tsikas D, Böhmer A

S-Transnitrosation reactions of hydrogen sulfide (H2S/HS-/S2-) with S-nitrosated cysteinyl thiols in phosphate buffer of pH 7.4: Results and review of the literature.

Nitric Oxide 2017; 65:22-36
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Tsikas D, Bollenbach A, Savvidou M D

Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction?

Amino Acids 2017; DOI: 10.1007/s00726-017-2522-2-
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Tsikas D, Eigendorf J

Diet and Exercise and Serum Markers of Oxidative Stress-Letter.

Cancer.Prev.Res.(Phila) 2017; 10(8):485-486
Letter
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Tsikas D, Hanff E

Lacking linearity in quantitative stable-isotope LC-MS/MS measurement of F2-isoprostanes is an irrefutable indicator of analytical inadequacy.

J.Chromatogr.B.Analyt Technol.Biomed.Life.Sci. 2017; 1064:139-142
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Tsikas D, Hanff E, Becker T

Drastic decrease of global l-arginine bioavailability during orthotopic liver transplantation: A matter of ATP deficiency of the graft?

Nitric Oxide 2017;73: 96-97; DOI: 10.1016/j.niox.2017.02.009-
Letter
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Tsikas D, Hanff E, Bollenbach A

S-Adenosyl-L-methionine towards hepatitis C virus expression: Need to consider S-adenosyl-L-methionine's chemistry, physiology and pharmacokinetics.

World J.Gastroenterol. 2017; 23(40):7343-7346
Letter
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Tsikas D, Hanff E, Brunner G

Helicobacter pylori, Its Urease and Carbonic Anhydrases, and Macrophage Nitric Oxide Synthase.

Trends Microbiol. 2017; 25(8):601-602
Letter
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Tsikas D, Hanff E, Brunner G

Spermidine for a long, dementia-free life?

Glob J Pharmaceu Sci 2017; 2(1):GJPPS.MS.ID.555576-
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Tsikas D, Kinzel M

Associations between asymmetric dimethylarginine (ADMA), nitrite-dependent renal carbonic anhydrase activity and plasma testosterone levels in hypogonadal men.

Hellenic J.Cardiol. 2017; DOI: 10.1016/j.hjc.2017.10.004-
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Tsikas D, Savvidou M

Plasma Oleic Acid Oxide in Women at Risk of Preeclampsia Correlates Inversely with Birthweight Centile.

JSM Biochem Mol Biol 2017; 4(2):1028-
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Tsikas D, Schwedhelm K S, Surdacki A, Giustarini D, Rossi R, Kukoc-Modun L, Kedia G, Ückert S

S-Nitroso-N-acetyl-L-cysteine ethyl ester (SNACET) and N-acetyl-L-cysteine ethyl ester (NACET) � Cysteine-based drug candidates with unique pharmacological profiles for oral use as NO, H2S and GSH suppliers and as antioxidants:Results and overview.

2017; 8(1):1-9; DOI: 10.1016/j.jpha.2017.12.003-
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von Elsner L, Hagemann S, Just I, Rohrbeck A

Anti-proliferative Effect of C3 Exoenzyme in Fibroblasts is Mediated by c-Jun Phosphorylation.

J Mol Signal 2017; 12(1-
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Yao G, Lam K H, Perry K, Weisemann J, Rummel A, Jin R

Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H.

Toxins (Basel) 2017; 9(3):93; DOI:10.3390/toxins9030093-
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Yao G, Lam K H, Weisemann J, Peng L, Krez N, Perry K, Shoemaker C B, Dong M, Rummel A, Jin R

A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.

Sci.Rep. 2017; 7(1):7438-
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Zanetti G, Sikorra S, Rummel A, Krez N, Duregotti E, Negro S, Henke T, Rossetto O, Binz T, Pirazzini M

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission.

PLoS Pathog. 2017; 13(8):DOI: 10.1371/journal.ppat.1006567-
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