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Veröffentlichungen 2017

 

 

Abere B, Mamo TM, Hartmann S, Samarina N, Hage E, Rückert J, Hotop SK, Büsche G, Schulz TF:

The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target.

PLoS Pathog 2017; 13(9): e1006639

 

Ackermann M, Gaumann A, Mentzer SJ, Hinrichs JB, Warnecke G, Hoeper MM, Braubach P, Kuehnel M, Maegel L, Jonigk D:

Plexiform Vasculopathy in Chronic Thromboembolic Pulmonary Hypertension.

Am J Respir Crit Care Med 2017; 196(8): e48-e51

 

Anwar SL, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A, Kreipe H, Buurman R, Skawran B, Lehmann U:

hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma.

World J Gastroenterol 2017; 23(9): 1568-1575

 

Anwar SL, Wulaningsih W, Lehmann U:

Transposable Elements in Human Cancer: Causes and Consequences of Deregulation.

Int J Mol Sci 2017; 18(5)

 

Banan R, Christians A, Bartels S, Lehmann U, Hartmann C:

Absence of MGMT promoter methylation in diffuse midline glioma, H3 K27M-mutant.

Acta Neuropathol Commun 2017; 5(1): 98 [Letter]

 

Banan R, Hartmann C:

The new WHO 2016 classification of brain tumors-what neurosurgeons need to know.

Acta Neurochir (Wien) 2017; 159(3): 403-418 [Review]

 

Barat S, Chen X, Cuong Bui K, Bozko P, Götze J, Christgen M, Krech T, Malek NP, Plentz RR:

Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44+ Gastric Cancer Stem Cells.

Stem Cells Transl Med 2017; 6(3): 819-829

 

Barrantes-Freer A, Engel AS, Rodríguez-Villagra OA, Winkler A, Bergmann M, Mawrin C, Kuempfel T, Pellkofer H, Metz I, Bleckmann A, Hernández-Durán S, Schippling S, Rushing EJ, Frank S, Glatzel M, Matschke J, Hartmann C, Reifenberger G, Müller W, Schildhaus HU, Brück W, Stadelmann C:

Diagnostic red flags: steroid-treated malignant CNS lymphoma mimicking autoimmune inflammatory demyelination.

Brain Pathol. 2017 Feb 18. doi: 10.1111/bpa.12496. [Epub ahead of print]

 

Bartels S, Faisal M, Büsche G, Schlue J, Kreipe H, Lehmann U:

Fibrotic progression in Polycythemia vera is associated with early concomitant driver-mutations besides JAK2.

Leukemia 2017 Sep 22. doi: 10.1038/leu.2017.298. [Epub ahead of print] No abstract available.

 

Bartels S, Persing S, Hasemeier B, Schipper E, Kreipe H, Lehmann U:

Molecular Analysis of Circulating Free DNA from Lung Cancer Patients in Routine Laboratory Practice: A Cross-Platform Comparison of Three Different Molecular Methods for Mutation Detection.

J Mol Diagn 2017; 19(5): 722-732

 

Beyer U, Brand F, Martens H, Weder J, Christians A, Elyan N, Hentschel B, Westphal M, Schackert G, Pietsch T, Hong B, Krauss JK, Samii A, Raab P, Das A, Dumitru CA, Sandalcioglu IE, Hakenberg OW, Erbersdobler A, Lehmann U, Reifenberger G, Weller M, Reijns MAM, Preller M, Wiese B, Hartmann C, Weber RG:

Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis.

Acta Neuropathol 2017; 134(6): 905-922

 

Bhayana S, Baisantry A, Kraemer TD, Wrede C, Hegermann J, Bräsen JH, Bockmeyer C, Ulrich Becker J, Ochs M, Gwinner W, Haller H, Melk A, Schmitt R:

Autophagy in kidney transplants of sirolimus treated recipients.

J Nephropathol 2017; 6(2): 90-96

 

Bräsen JH, Khalifa A, Schmitz J, Dai W, Einecke G, Schwarz A, Hallensleben M, Schmidt BM, Kreipe HH, Haller H, von Vietinghoff S:

Macrophage density in early surveillance biopsies predicts future renal transplant function.

Kidney Int. 2017; 92(2): 479-489

 

Braubach P, Lippmann T, Raoult D, Lagier JC, Anagnostopoulos I, Zender S, Länger FP, Kreipe HH, Kühnel MP, Jonigk D:

Fluorescence In Situ Hybridization for Diagnosis of Whipple's Disease in Formalin-Fixed Paraffin-Embedded Tissue.

Front Med (Lausanne) 2017; 4: 87

 

Braulke F, Schulz X, Germing U, Schuler E, Platzbecker U, Nolte F, Hofmann WK, Giagounidis A, Götze K, Lübbert M, Schlenk RF, Schanz J, Bacher U, Ganser A, Büsche G, Letsch A, Schafhausen P, Bug G, Brümmendorf TH, Haas R, Trümper L, Shirneshan K, Haase D:

Peripheral blood cytogenetics allows treatment monitoring and early identification of treatment failure to lenalidomide in MDS patients: results of the LE-MON-5 trial.

Ann Hematol.2017; 96(6): 887-894

 

Bräsen JH, Khalifa A, Schmitz J, Dai W, Einecke G, Schwarz A, Hallensleben M, Schmidt BMW, Kreipe HH, Haller H, von Vietinghoff S:

Macrophage density in early surveillance biopsies predicts future renal transplant function.

Kidney Int 2017; 92(2): 479-489

 

Calvier L, Chouvarine P, Legchenko E, Hoffmann N, Geldner J, Borchert P, Jonigk D, Mozes MM, Hansmann G:

PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism.

Cell Metab 2017; 25(5): 1118-1134.e7

 

Christgen M, Bartels S, van Luttikhuizen JL, Schieck M, Pertschy S, Kundu S, Lehmann U, Sander B, Pelz E, Länger F, Schlegelberger B, Steinemann D, Kreipe H:

Subclonal analysis in a lobular breast cancer with classical and solid growth pattern mimicking a solid-papillary carcinoma.

J Pathol Clin Res 2017; 3(3): 191-202

 

Cramer L, Brix A, Matin E, Rühli F, Hussein K:

Computed Tomography-Detected Paleopathologies in Ancient Egyptian Mummies.

Curr Probl Diagn Radiol 2017: pii: S0363-0188(16)30131-1 [Review]

 

Derlin T, Braubach P, Kreipe HH, Hueper K:

18F-FDG PET for Detection of Primary Tracheobronchial T-/Natural Killer-Cell-Derived Posttransplant Lymphoproliferative Disorder After Lung Transplantation.

Clin Nucl Med 2017; 42(12): 988-989

 

Derlin T, Gueler F, Bräsen JH, Schmitz J, Hartung D, Herrmann TR, Ross TL, Wacker F, Wester HJ, Hiss M, Haller H, Bengel FM, Hueper K:

Integrating MRI and chemokine receptor CXCR4-targeted PET for detection of leukocyte infiltration in complicated urinary tract infections after kidney transplantation.

J Nucl Med 2017; 58(11): 1831-1837

 

Derlin T, Hueper K, Soudah B:

68Ga-DOTA-TATE PET/CT for Molecular Imaging of Somatostatin Receptor Expression in Metastasizing Epithelioid Hemangioendothelioma: Comparison With 18F-FDG.

Clin Nucl Med 2017; 42(11): e478-e479

 

Derlin T, Kreipe HH, Schumacher U, Soudah B:

PSMA Expression in Tumor Neovasculature Endothelial Cells of Follicular Thyroid Adenoma as Identified by Molecular Imaging Using 68Ga-PSMA Ligand PET/CT.

Clin Nucl Med 2017; 42(3): e173-e174

 

Diestelhorst J, Junge N, Schlue J, Falk CS, Manns MP, Baumann U, Jaeckel E, Taubert R:

 

Dommaschk A, Ding N, Tort Tarres M, Bittersohl LF, Maus R, Stolper J, Jonigk D, Braubach P, Lippmann T, Welte T, Maus UA:

Nasopharyngeal colonization with Streptococcus pneumoniae triggers dendritic cell dependent antibody responses against invasive disease in mice.

Eur J Immunol 2017; 47(3): 540-551

 

Dywicki J, Noyan F, Misslitz AC, Hapke M, Galla M, Schlue J, Liblau RS, Taubert R, Manns MP, Jaeckel E, Hardtke-Wolenski M:

Hepatic T Cell Tolerance Induction in An Inflammatory Environment.

Dig Dis 2017 Oct 12. doi: 10.1159/000481341. [Epub ahead of print]

 

Fassunke J, Ihle MA, Lenze D, Lehmann A, Hummel M, Vollbrecht C, Penzel R, Volckmar AL, Stenzinger A, Endris V, Jung A, Lehmann U, Zeugner S, Baretton G, Kreipe H, Schirmacher P, Kirchner T, Dietel M, Büttner R, Merkelbach-Bruse S:

EGFR T790M mutation testing of non-small cell lung cancer tissue and blood samples artificially spiked with circulating cell-free tumor DNA: results of a round robin trial.

Virchows Arch 2017; 471(4): 509-520

 

Gluz O, Nitz U, Liedtke C, Christgen M, Grischke EM, Forstbauer H, Braun M, Warm M, Hackmann J, Uleer C, Aktas B, Schumacher C, Bangemann N, Lindner C, Kuemmel S, Clemens M, Potenberg J, Staib P, Kohls A, von Schumann R, Kates R, Kates R, Schumacher J, Wuerstlein R, Kreipe HH, Harbeck N:

Comparison of Neoadjuvant Nab-Paclitaxel+Carboplatin vs Nab-Paclitaxel+Gemcitabine in Triple-Negative Breast Cancer: Randomized WSG-ADAPT-TN Trial Results.

J Natl Cancer Inst. 2017 Dec 8. doi: 10.1093/jnci/djx258. [Epub ahead of print]

 

Hansen-Hagge C, Bräsen JH, Kielstein JT:

[Acute kidney injury from intravenous immunoglobulins - an avoidable complication].

Z Rheumatol 2017; 76(3): 279-280

 

Harbeck N, Gluz O, Christgen M, Kates RE, Braun M, Küemmel S, Schumacher C, Potenberg J, Kraemer S, Kleine-Tebbe A, Augustin D, Aktas B, Forstbauer H, Tio J, von Schumann R, Liedtke C, Grischke EM, Schumacher J, Wuerstlein R, Kreipe HH, Nitz UA:

De-Escalation Strategies in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Early Breast Cancer (BC): Final Analysis of the West German Study Group Adjuvant Dynamic Marker-Adjusted Personalized Therapy Trial Optimizing Risk Assessment and Therapy Response Prediction in Early BC HER2- and Hormone Receptor-Positive Phase II Randomized Trial-Efficacy, Safety, and Predictive Markers for 12 Weeks of Neoadjuvant Trastuzumab Emtansine With or Without Endocrine Therapy (ET) Versus Trastuzumab Plus ET.

J Clin Oncol 2017; 35(26): 3046-3054

 

Hardtke-Wolenski M, Dywicki J, Fischer K, Hapke M, Sievers M, Schlue J, Anderson MS, Taubert R, Noyan F, Manns MP, Jaeckel E:

The influence of genetic predisposition and autoimmune hepatitis inducing antigens in disease development.

J Autoimmun 2017; 78: 39-45

 

Harms A, Kriegsmann M, Fink L, Länger F, Warth A:

[The new TNM classification for lung tumors : Changes and the assessment of multiple tumor foci].

Pathologe 2017; 38(1): 11-20 [German]

 

Harms J, Kunzmann B, Reineke-Plaass T, Kreipe HH, Reinecke-Lüthge A, Czymek R, Jungbluth T:

[Colorectal cancer and associated sebaceous gland carcinoma - a syndrome?]

Chirurg 2017; 88(8): 699-701 [German]

 

Hartung D, Hueper K, Chen R, Gutberlet M, Wacker F, Meier M, Rong S, Jang MS, Bräsen JH, Gueler F:

T2 Mapping for Noninvasive Assessment of Interstitial Edema in Acute Cardiac Allograft Rejection in a Mouse Model of Heterotopic Heart Transplantation.

Invest Radiol. 2017 Dec 19. doi: 10.1097/RLI.0000000000000438. [Epub ahead of print]

 

Heinemann FM, Jindra PT, Bockmeyer CL, Zeuschner P, Wittig J, Höflich H, Eßer M, Abbas M, Dieplinger G, Stolle K, Vester U, Hoyer PF, Immenschuh S, Heinold A, Horn PA, Li W, Eisenberger U, Becker JU:

Glomerulocapillary miRNA response to HLA-class I antibody in vitro and in vivo.

Sci Rep 2017; 7(1): 14554

 

Hess R, Wujak L, Hesse C, Sewald K, Jonigk D, Warnecke G, Fieguth HG, de Maat S, Maas C, Bonella F, Preissner KT, Weiss B, Schaefer L, Kuebler WM, Markart P, Wygrecka M:

Coagulation factor XII regulates inflammatory responses in human lungs.

Thromb Haemost 2017; 117(10): 1896-1907

 

Hetzel M, Mucci A, Blank P, Nguyen AHH, Schiller J, Halle O, Kühnel MP, Billig S, Meineke R, Brand D, Herder V, Baumgärtner W, Bange FC, Goethe R, Jonigk D, Förster R, Gentner B, Casanova JL, Bustamante J, Schambach A, Kalinke U, Lachmann N:

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections.

Blood. 2017 Dec 12. pii: blood-2017-10-812859. doi: 10.1182/blood-2017-10-812859. [Epub ahead of print]

 

Heuser M, Gabdoulline R, Löffeld P, Dobbernack V, Kreimeyer H, Pankratz M, Flintrop M, Liebich A, Klesse S, Panagiota V, Stadler M, Wichmann M, Shahswar R, Platzbecker U, Thiede C, Schroeder T, Kobbe G, Geffers R, Schlegelberger B, Göhring G, Kreipe HH, Germing U, Ganser A, Kröger N, Koenecke C, Thol F:

Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation.

Ann Hematol 2017; 96(8): 1361-1372

 

Hong B, Hermann EJ, Feuerhake F, Krauss JK:

Secondary extradural spinal manifestation of esthesioneuroblastoma.

Br J Neurosurg. 2017 Oct 31:1-3. doi: 10.1080/02688697.2017.1396285. [Epub ahead of print]

 

Hueper K, Schmidbauer M, Thorenz A, Bräsen JH, Gutberlet M, Mengel M, Hartung D, Chen R, Meier M, Haller H, Wacker F, Rong S, Gueler F:

Longitudinal evaluation of perfusion changes in acute and chronic renal allograft rejection using arterial spin labeling in translational mouse models.

J Magn Reson Imaging 2017; 46(6): 1664-1672

 

Hussein K, Panning B:

[Reconstruction of the examination of the laryngeal carcinoma of Emperor Frederick III by Rudolf Virchow].

Pathologe. 2017 Nov 16. doi: 10.1007/s00292-017-0392-8. [Epub ahead of print] Review. German.

 

Hussein K, Stucki-Koch A, Göhring G, Kreipe H, Suttorp M:

Increased megakaryocytic proliferation, pro-platelet deposition and expression of fibrosis-associated factors in children with chronic myeloid leukaemia with bone marrow fibrosis.

Leukemia 2017; 31(7): 1540-1546

 

Jansson K, Dreckmann K, Sommer W, Avsar M, Salman J, Siemeni T, Knöfel AK, Pauksch L, Gottlieb J, Frühauf J, Werner M, Jonigk D, Strüber M, Haverich A, Warnecke G:

Splenocyte Infusion and Whole-Body Irradiation for Induction of Peripheral Tolerance in Porcine Lung Transplantation: Modifications of the Preconditioning Regime for Improved Clinical Feasibility.

Transplant Direct 2017; 3(7): e170

 

Jeinsen N, Maegel L, Jonigk D, Klingenberg M, Haverich A, Wilhelmi M, Böer U:

Biocompatibility of intensified decellularized equine carotid arteries in a rat subcutaneous implantation model and in a human in vitro-model.

Tissue Eng Part A. 2017 May 20. doi: 10.1089/ten.TEA.2016.0542. [Epub ahead of print]

 

Kampers J, Orjuela-Grimm M, Schober T, Schulz TF, Stiefel M, Klein C, Körholz D, Mauz-Körholz C, Kreipe H, Beier R, Maecker-Kolhoff B:

Classical Hodgkin lymphoma-type PTLD after solid organ transplantation in children: a report on 17 patients treated according to subsequent GPOH-HD treatment schedules.

Leuk Lymphoma 2017; 58(3): 633-638

 

Karadagi A, Johansson H, Zemack H, Salipalli S, Mörk LM, Kannisto K, Jorns C, Gramignoli R, Strom S, Stokkeland K, Ericzon BG, Jonigk D, Janciauskiene S, Nowak G, Ellis ECS:

Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression.

PLoS One 2017; 12(5): e0177279

 

Keller G, Steinmann D, Quaas A, Grünwald V, Janssen S, Hussein K:

New concepts of personalized therapy in salivary gland carcinomas.

Oral Oncol 2017; 68: 103-113 [Review]

 

Kirstein MM, Schweitzer N, Winter T, Lappas K, Graen N, Kunstmann I, Voigtländer T, Reineke-Plaaß T, Manns MP, Lehner F, Rodt T, Vogel A:

Patterns and challenges of treatment sequencing in patients with hepatocellular carcinoma -experience from a referral center.

J Gastroenterol Hepatol 2017; 32(10): 1730-1738

 

Kosfeld A, Brand F, Weiss AC, Kreuzer M, Goerk M, Martens H, Schubert S, Schäfer AK, Riehmer V, Hennies I, Bräsen JH, Pape L, Amann K, Krogvold L, Bjerre A, Daniel C, Kispert A, Haffner D, Weber RG:

Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations.

Hum Mol Genet 2017; 26(9): 1716-1731

 

Kröger N, Panagiota V, Badbaran A, Zabelina T, Triviai I, Araujo Cruz MM, Shahswar R, Ayuk F, Gehlhaar M, Wolschke C, Bollin R, Walter C, Dugas M, Wiehlmann L, Lehmann U, Koenecke C, Chaturvedi A, Alchalby H, Stadler M, Eder M, Christopeit M, Göhring G, Koenigsmann M, Schlegelberger B, Kreipe HH, Ganser A, Stocking C, Fehse B, Thol F, Heuser M.

Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2017; 23(7): 1095-1101

 

Kuehnel M, Maegel L, Vogel-Claussen J, Robertus JL, Jonigk D:

Airway remodelling in the transplanted lung.

Cell Tissue Res 2017; 367(3): 663-675

 

Loosen SH, Schmeding M, Roderburg C, Binnebösel M, Temizel I, Mottaghy FM, Tischendorf JJ, Tacke F, Gaisa NT, Hussein K, Lehmann U, Trautwein C, Neumann UP, Luedde T:

A liver nodule in a patient transplanted for primary sclerosing cholangitis: an interdisciplinary diagnostic approach.

Z Gastroenterol 2017; 55(1): 56-62

 

Lordick F, Al-Batran SE, Dietel M, Gaiser T, Hofheinz RD, Kirchner T, Kreipe HH, Lorenzen S, Möhler M, Quaas A, Röcken C, Rüschoff J, Tannapfel A, Thuss-Patience P, Baretton G:

HER2 testing in gastric cancer: results of a German expert meeting.

J Cancer Res Clin Oncol 2017; 143(5): 835-841

 

Lu H, Galeano MCR, Ott E, Kaeslin G, Kausalya PJ, Kramer C, Ortiz-Brüchle N, Hilger N, Metzis V, Hiersche M, Tay SY, Tunningley R, Vij S, Courtney AD, Whittle B, Wühl E, Vester U, Hartleben B, Neuber S, Frank V, Little MH, Epting D, Papathanasiou P, Perkins AC, Wright GD, Hunziker W, Gee HY, Otto EA, Zerres K, Hildebrandt F, Roy S, Wicking C, Bergmann C:

Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease.

Nat Genet 2017; 49(7): 1025-1034

 

Lüdemann W, Banan R, Hartmann C, Bertalanffy H, Di Rocco C:

Pediatric intracranial primary anaplastic ganglioglioma.

Childs Nerv Syst 2017; 33(2): 227-231

 

Martens S, Jeong M, Tonnus W, Feldmann F, Hofmans S, Goossens V, Takahashi N, Bräsen JH, Lee EW, Van der Veken P, Joossens J, Augustyns K, Fulda S, Linkermann A, Song J, Vandenabeele P:

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury.

Cell Death Dis 2017; 8(6): e2904

 

Massenkeil G, Gropp C, Kreipe H, Hussein K:

[Analysis of therapy-relevant receptors in bone marrow carcinosis : Comparison of pathological and clinical parameters].

Pathologe 2017; 38(4): 317-323 [German]

 

Müller A, Hussein K:

Meta-analysis of teeth from European populations before and after the 18th century reveals a shift towards increased prevalence of caries and tooth loss.

Arch Oral Biol 2017; 73: 7-15

 

Müller T, Dewitz C, Schmitz J, Schröder AS, Bräsen JH, Stockwell BR, Murphy JM, Kunzendorf U, Krautwald S:

Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure.

Cell Mol Life Sci 2017; 74(19): 3631-3645

 

Müller-Deile J, Bräsen JH, Pollheimer M, Ratschek M, Haller H, Pape L, Schiffer M:

Graft Growth and Podocyte Dedifferentiation in Donor-Recipient Size Mismatch Kidney Transplants.

Transplant Direct 2017; 3(10): e210

 

Müller-Deile J, Dannenberg J, Schroder P, Lin MH, Miner JH, Chen R, Bräsen JH, Thum T, Nyström J, Staggs LB, Haller H, Fiedler J, Lorenzen JM, Schiffer M:

Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases.

Kidney Int 2017; 92(4): 836-849

 

Neehus AL, Lam J, Haake K, Merkert S, Schmidt N, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Blank P, Philipp F, Goethe R, Jonigk D, Martin U, Kalinke U, Baumann U, Schambach A, Roesler J, Lachmann N:

Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages.

Stem Cell Reports. 2017 Dec 12. pii: S2213-6711(17)30518-0. doi: 10.1016/j.stemcr.2017.11.011. [Epub ahead of print]

 

Neuhaus V, Schaudien D, Golovina T, Temann UA, Thompson C, Lippmann T, Bersch C, Pfennig O, Jonigk D, Braubach P, Fieguth HG, Warnecke G, Yusibov V, Sewald K, Braun A:

Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality.

J Occup Med Toxicol 2017; 12: 13

 

Neyazi B, Herz A, Stein KP, Gawish I, Hartmann C, Wilkens L, Erguen S, Dumitru CA, Sandalcioglu IE:

Brain arteriovenous malformations: implications of CEACAM1-positive inflammatory cells and sex on hemorrhage.

Neurosurg Rev 2017; 40(1): 129-134

 

Neyazi B, Tanrikulu L, Wilkens L, Hartmann C, Stein KP, Dumitru CA, Sandalcioglu IE:

Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) expression in brain arteriovenous malformations (bAVM) and its association with bAVM size.

World Neurosurg 2017; 102: 79-84

 

Nitz UA, Gluz O, Christgen M, Grischke EM, Augustin D, Kuemmel S, Braun M, Potenberg J, Kohls A, Krauss K, Stefek A, Schumacher C, Forstbauer H, Reimer T, Fischer H, Liedtke C, Wuerstlein R, Schumacher J, Kates R, Kreipe HH, Harbeck N; West-German Study Group (WSG)-ADAPT investigators:

De-escalation strategies in HER2-positive early breast cancer (EBC): Final analysis of the WSG-ADAPT HER2+/HR- phase II trial: Efficacy, safety, and predictive markers for 12-weeks of neoadjuvant dual blockade with trastuzumab and pertuzumab ± weekly paclitaxel.

Ann Oncol 2017; 28(11): 2768-2772

 

Nitz U, Gluz O, Christgen M, Kates RE, Clemens M, Malter W, Nuding B, Aktas B, Kuemmel S, Reimer T, Stefek A, Lorenz-Salehi F, Krabisch P, Just M, Augustin D, Liedtke C, Chao C, Shak S, Wuerstlein R, Kreipe HH, Harbeck N:

Reducing chemotherapy use in clinically high-risk, genomically low-risk pN0 and pN1 early breast cancer patients: five-year data from the prospective, randomised phase 3 West German Study Group (WSG) PlanB trial.

Breast Cancer Res Treat 2017; 165(3): 573-583

 

Pape L, Bräsen JH, Schiffer, M:

Transplantatversagen.

Der Nephrologe 2017; 1-9  doi.org/10.1007/s11560-017-0214-2. [German]

 

Patecki M, Lehmann G, Bräsen JH, Schmitz J, Bertram A, Berthold LD, Haller H, Gwinner W:

A case report of severe calciphylaxis - suggested approach for diagnosis and treatment.

BMC Nephrol 2017; 18(1): 137

 

Petersen I, Dietel M, Geilenkeuser WJ, Mireskandari M, Weichert W, Steiger K, Scheel AH, Büttner R, Schirmacher P, Warth A, Lasitschka F, Schildhaus HU, Kirchner T, Reu S, Kreipe H, Länger F, Tiemann M, Schulte C, Jöhrens K:

EGFR immunohistochemistry as biomarker for antibody-based therapy of squamous NSCLC - Experience from the first ring trial of the German Quality Assurance Initiative for Pathology (QuIP®).

Pathol Res Pract 2017; 213(12): 1530-1535

 

Raap M, Ließem S, Rüschoff J, Fisseler-Eckhoff A, Reiner A, Dirnhofer S, von Wasielewski R, Kreipe H:

Quality assurance trials for Ki67 assessment in pathology.

Virchows Arch 2017; 471(4): 501-508

 

Riehle C, Scharf GM, Sieweke JT, Zauner F, Flierl U, Treptau J, Zormpas C, Senf J, McCarty NS, Bauersachs J, Sedding DG, Westhoff-Bleck M:

Leukocytoclastic vasculitis associated with endocarditis in a patient with transposition of the great arteries and mechanical valve replacement.

Cardiovasc Pathol 2017; 27: 68-70

 

Ringshausen FC, Nothdorft S, Länger F, Stoll M:

[Endobronchial Dissemination of Metastatic Melanoma without Apparent Primary Tumor].

Pneumologie 2017; 71(9): 587-589 [German]

 

Röcken C, Baretton GB, Kreipe HH, Kirchner T:

[University Pathology in Germany].

Pathologe 2017; 38(4): 324-330 [German]

 

Rüschoff J, Lebeau A, Kreipe H, Sinn P, Gerharz CD, Koch W, Morris S, Ammann J, Untch M; Nicht-interventionelle Untersuchung (NIU) HER2 Study Group..

Assessing HER2 testing quality in breast cancer: variables that influence HER2 positivity rate from a large, multicenter, observational study in Germany.

Mod Pathol 2017; 30(2): 217-226

 

Salmoukas C, Ruemke S, Bräsen JH, Haverich A, Teebken OE:

Renal artery revascularization by using the Riolan anastomosis as feeding vessel in a patient with abdominal aortic coarctation due to fibromuscular dysplasia.

Vasa 2017; 20: 1-6

 

Schaadt NS, Alfonso JCL, Schönmeyer R, Grote A, Forestier G, Wemmert C, Krönke N, Stoeckelhuber M, Kreipe HH, Hatzikirou H, Feuerhake F:

Image analysis of immune cell patterns in the human mammary gland during the menstrual cycle refines lymphocytic lobulitis.

Breast Cancer Res Treat 2017; 164(2): 305-315

 

Schenk H, Müller-Deile J, Schmitt R, Bräsen JH, Haller H, Schiffer M:

Removal of focal segmental glomerulosclerosis (FSGS) factor suPAR using CytoSorb.

J Clin Apher 2017; 32(6): 444-452

 

Schlenk RF, Stegelmann F, Reiter A, Jost E, Gattermann N, Hebart H, Waller C, Hochhaus A, Platzbecker U, Schafhausen P, Blau IW, Verbeek W, Heidel FH, Werner M, Kreipe H, Teleanu V, Benner A, Döhner H, Grießhammer M, Döhner K:

Pomalidomide in myeloproliferative neoplasm-associated myelofibrosis.

Leukemia 2017; 31(4): 889-895

 

Schmidt H, Michel C, Braubach P, Fauler M, Neubauer D, Thompson KE, Frick M, Mizaikoff B, Dietl P, Wittekindt OH:

Water Permeability Adjusts Resorption in Lung Epithelia to Increased Apical Surface Liquid Volumes.

Am J Respir Cell Mol Biol 2017; 56(3): 372-382

 

Schmidt JJ, Kielstein JT, Bräsen JH:

Stellenwert der Nierenbiopsie bei akuter Nierenschädigung.

Der Nephrologe 2017; 12(5): 323-328 [German]

 

Schneider RK, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, Van Strien PMH, Bindels EM, Heckl D, Büsche G, Fleck D, Müller-Newen G, Wongboonsin J, Ventura Ferreira M, Puelles VG, Saez-Rodriguez J, Ebert BL, Humphreys BD, Kramann R:

Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.

Cell Stem Cell 2017; 20(6): 785-800.e8

 

Schnitzler LJ, Schreckenbach T, Nadaj-Pakleza A, Stenzel W, Rushing EJ, Van Damme P, Ferbert A, Petri S, Hartmann C, Bornemann A, Meisel A, Petersen JA, Tousseyn T, Thal DR, Reimann J, De Jonghe P, Martin JJ, Van den Bergh PY, Schulz JB, Weis J, Claeys KG:

Sporadic late-onset nemaline myopathy: clinico-pathological characteristics and review of 76 cases.

Orphanet J Rare Dis 2017; 12(1): 86 [Review]

 

Schober T, Magg T, Laschinger M, Rohlfs M, Linhares ND, Puchalka J, Weisser T, Fehlner K, Mautner J, Walz C, Hussein K, Jaeger G, Kammer B, Schmid I, Bahia M, Pena SD, Behrends U, Belohradsky BH, Klein C, Hauck F:

A human immunodeficiency syndrome caused by mutations in CARMIL2.

Nat Commun 2017; 8: 14209

 

Schulte K, Vollmer C, Klasen V, Bräsen JH, Püchel J, Borzikowsky C, Kunzendorf U, Feldkamp T:

Late conversion from tacrolimus to a belatacept-based immuno-suppression regime in kidney transplant recipients improves renal function, acid-base derangement and mineral-bone metabolism.

J Nephrol 2017; 30(4): 607-615

 

Schweitzer N, Fischer M, Kirstein MM, Berhane S, Kottas M, Sinn M, Gonzalez-Carmona MA, Balta Z, Weismüller TJ, Strassburg CP, Reineke-Plaaß T, Bektas H, Manns MP, Johnson P, Weinmann A, Vogel A:

Risk estimation for biliary tract cancer: Development and validation of a prognostic score.

Liver Int 2017; 37(12): 1852-1860

 

Schweitzer N, Weber T, Kirstein MM, Fischer M, Kratzel AM, Reineke-Plaaß T, Lehner F, Manns MP, Vogel A:

The effect of adjuvant chemotherapy in patients with intrahepatic cholangiocarcinoma: a matched pair analysis.

J Cancer Res Clin Oncol 2017; 143(7): 1347-1355

 

Sommer W, Buechler G, Jansson K, Avsar M, Knöfel AK, Salman J, Hoeffler K, Siemeni T, Gottlieb J, Karstens JH, Jonigk D, Reising A, Haverich A, Strüber M, Warnecke G:

Irradiation before and donor splenocyte infusion immediately after transplantation induce tolerance to lung, but not heart allografts in miniature swine.

Transpl Int 2017; 30(4): 420-431

 

Soergel P, Hillemanns P, Klapdor R, Jentschke M, Christgen M, Hertel H:

Sentinel lymphadenectomy in early vaginal cancer using combined near infrared fluorescence from indocynine green and technetium-99m nanocolloid - first case report.

Clinical Obstetrics, Gynecology and Reproductive Medicine 2017; doi: 10.15761/COGRM.1000182

 

Stauber M, Boldt K, Wrede C, Weidemann M, Kellner M, Schuster-Gossler K, Kühnel MP, Hegermann J, Ueffing M, Gossler A:

1700012B09Rik, a FOXJ1 effector gene active in ciliated tissues of the mouse but not essential for motile ciliogenesis.

Dev Biol 2017; 429(1): 186-199

 

Taubert R, Hardtke-Wolenski M, Noyan F, Lalanne C, Jonigk D, Schlue J, Krech T, Lichtinghagen R, Falk CS, Schlaphoff V, Bantel H, Muratori L, Manns MP, Jaeckel E:

Hyperferritinemia and hypergammaglobulinemia predict the treatment response to standard therapy in autoimmune hepatitis.

PLoS One 2017; 12(6): e0179074

 

Teiken K, Kreipe H, Maecker-Kolhoff B, Hussein K:

Variant of classical high grade PTLD: post-transplant EBV-negative T cell lymphoblastic leukaemia after solid organ transplantation.

Ann Hematol 2017; 96(8): 1403-1405

 

Temam S, Spicer J, Farzaneh F, Soria JC, Oppenheim D, McGurk M, Hollebecque A, Sarini J, Hussain K, Soehrman Brossard S, Manenti L, Evers S, Delmar P, Di Scala L, Mancao C, Feuerhake F, Andries L, Ott MG, Passioukov A, Delord JP:

An exploratory, open-label, randomized, multicenter study to investigate the pharmacodynamics of a glycoengineered antibody (imgatuzumab) and cetuximab in patients with operable head and neck squamous cell carcinoma.

Ann Oncol 2017; 28(11): 2827-2835

 

Thomay K, Fedder C, Hofmann W, Kreipe H, Stadler M, Titgemeyer J, Zander I, Schlegelberger B, Göhring G:

Telomere shortening, TP53 mutations and deletions in chronic lymphocytic leukemia result in increased chromosomal instability and breakpoint clustering in heterochromatic regions.

Ann Hematol 2017; 96(9): 1493-1500

 

Thorenz A, Völker N, Bräsen JH, Chen R, Jang MS, Rong S, Haller H, Kirsch T, Vieten G, Klemann C, Gueler F:

IL-17A blockade or deficiency does not affect progressive renal fibrosis following renal ischaemia reperfusion injury in mice.

J Pharm Pharmacol 2017; 69(9): 1125-1135

 

Valent P, Akin C, Arock M, Bock C, George TI, Galli SJ, Gotlib J, Haferlach T, Hoermann G, Hermine O, Jäger U, Kenner L, Kreipe H, Majeti R, Metcalfe DD, Orfao A, Reiter A, Sperr WR, Staber PB, Sotlar K, Schiffer C, Superti-Furga G, Horny HP:

Proposed Terminology and Classification of Pre-Malignant Neoplastic Conditions: A Consensus Proposal.

EBioMedicine 2017; 26: 17-24 [Review]

 

Voigtländer T, Alten TA, Kirstein MM, Lehner F, Manns MP, Schlué J, Wedemeyer H, Lankisch TO:

Clinical Impact of Liver Biopsies in Liver Transplant Recipients.

Ann Transplant 2017; 22: 108-114

 

Vondran FWR, Wintterle S, Bräsen JH, Haller H, Klempnauer J, Richter N, Lehner F, Schiffer M:

[Transplant Surgeon Meets Nephrologist: Important Nephrological Aspects Before and After Kidney or Liver Transplantation].

Zentralbl Chir 2017; 142(2): 180-188

 

Weissinger EM, Human C, Metzger J, Hambach L, Wolf D, Greinix HT, Dickinson AM, Mullen W, Jonigk D, Kuzmina Z, Kreipe H, Schweier P, Böhm O, Türüchanow I, Ihlenburg-Schwarz D, Raad J, Durban A, Schiemann M, Könecke C, Diedrich H, Holler E, Beutel G, Krauter J, Ganser A, Stadler M:

The proteome pattern cGvHD_MS14 allows early and accurate prediction of chronic GvHD after allogeneic stem cell transplantation.

Leukemia 2017; 31(3): 654-662

 

Wimmer K, Beilken A, Nustede R, Ripperger T, Lamottke B, Ure B, Steinmann D, Reineke-Plaass T, Lehmann U, Zschocke J, Valle L, Fauth C, Kratz CP:

A novel germline POLE mutation causes an early onset cancer prone syndrome mimicking constitutional mismatch repair deficiency.

Fam Cancer 2017; 16(1): 67-71

 

Wujak L, Hesse C, Sewald K, Jonigk D, Braubach P, Warnecke G, Fieguth HG, Braun A, Lochnit G, Markart P, Schaefer L, Wygrecka M:

FXII promotes proteolytic processing of the LRP1 ectodomain.

Biochim Biophys Acta 2017; 1861(8): 2088-2098

 

Yang M, Pan Z, Huang K, Büsche G, Feuerhake F, Chaturvedi A, Nie D, Heuser M, Thol F, von Neuhoff N, Ganser A, Li Z:

Activation of TRKA receptor elicits mastocytosis in mice and is involved in the development of resistance to KIT-targeted therapy.

Oncotarget 2017; 8(43): 73871-73883

 

Yesilöz Ü, Kirches E, Hartmann C, Scholz J, Kropf S, Sahm F, Nakamura M, Mawrin C:

Frequent AKT1E17K mutations in skull base meningiomas are associated with mTOR and ERK1/2 activation and reduced time to tumor recurrence.

Neuro Oncol 2017; 19(8): 1088-1096

 

Zhang R, Mägel L, Jonigk D, Länger F, Lippmann T, Zardo P, Pölzing F:

Biosynthetic Nanostructured Cellulose Patch for Chest Wall Reconstruction: Five-Month Follow-up in a Porcine Model.

J Invest Surg 2017; 30(5): 297-302