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2016

Frädrich C, Beer LA, Gerhard R

Reactive Oxygen Species as Additional Determinants for Cytotoxicity of Clostridium difficile Toxins A and B

Toxins (Basel) 2016; 8 (1), 25
Übersicht
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Böhmer A, Pich A, Schmidt M, Haghikia A, Tsikas D

Evidence by chromatography and mass spectrometry that inorganic nitrite induces S-glutathionylation of hemoglobin in human red blood cells

Journal of Chromatography B. Analyt Technol.Biomed.Life.Sci. 2016; 1019 (72-82)
Originalpublikation
Abstract



Adolf A, Leondaritis G, Rohrbeck A, Eickholt BJ, Just I, Ahnert-Hilger G, Höltje M

The intermediate filament protein vimentin is essential for axonotrophic effects of Clostridium botulinum C3 exoenzyme

Journal of Neurochemistry 2016; 139 (2): 234-244
Originalpublikation
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Dong L, Helmke A, Waisman A, Haller H, Pich A, von Vietinghoff S

Surface-bound bovine serum albumin carrier protein as present in recombinant cytokine preparations amplifies T helper 17 cell polarization

Scientific Reports 2016; 6 (36598-)
Originalpublikation
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Dorner BG, Zeleny R, Harju K, Hennekinne JA, Vanninen P, Schimmel H, Rummel A

Biological toxins of potential bioterrorism risk: Current status of detection and identification technology 

TrAC Trends in Analytical Chemistry 2016; 85 (Part B): 89-102
Übersicht
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Gerhard R

Receptors and Binding Structures for Clostridium difficile Toxins A and B

Current Topics in Microbiology and Immunology 2016: 1-18
Originalpublikation
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Krueger J, Pohl S, Preusse M, Kordes A, Rugen N, Schniederjans M, Pich A, Häussler S

Unravelling post-transcriptional PrmC-dependent regulatory mechanisms in Pseudomonas aeruginosa

Environmental Microbiology 2016; 18 (10): 3583-3592
Originalpublikation
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Mahrhold S, Bergström T, Stern D, Dorner BG, Astot C, Rummel A

Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1

Biochemical Journal 2016; 473 (17): 2645-2654
Originalpublikation
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Rohrbeck A, Fühner V, Schröder A, Hagemann S, Vu XK, Berndt S, Hust M, Pich A, Just I

Detection and Quantification of ADP-Ribosylated RhoA/B by Monoclonal Antibody

Toxins (Basel) 2016; 8(4):100
Originalpublikation
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Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, Zhang X, Stallcup WB, Miao J, He X, Hurdle JG, Breault DT, Brass AL, Dong M

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B

Nature 2016; 538(7625): 350-355
Originalpublikation
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von Elsner L, Hagemann S, Just I, Rohrbeck A

C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors

Naunyn Schmiedeberg's Archives of Pharmacology 2016; 389 (9): 1021-1031
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Weisemann J, Stern D, Mahrhold S, Dorner BG, Rummel A

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin

Toxins (Basel) 2016; 8(5), 154
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Yao G, Zhang S, Mahrhold S, Lam KH, Stern D, Bagramyan K, Perry K, Kalkum M, Rummel A, Dong M, Jin R

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A

Nature Structural & Molecular Biology 2016; 23 (7): 656-662
Originalpublikation
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Zhang G, Chan B, Samarina N, Abere B, Weidner-Glunde M, Buch A, Pich A, Brinkmann MM, Schulz TF

Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS

Proc.Natl.Acad.Sci.U.S.A. 2016; 113 (8): E1034-E1043
Originalpublikation
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Junemann J, Birgin G, Erdmann J, Schröder A, Just I, Gerhard R, Pich A

Toxin A of the nosocomial pathogen Clostridium difficile induces primary effects in the proteome of HEp-2 cells

Germany : WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, Proteomics Clinical Applications 2016; 11 (3-4) 
Originalpublikation 
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Genth H, Schelle I, Just I

Metal Ion Activation of Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B

Toxins (Basel) 2016; 8 (4): 109
Originalpublikation
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Hansbauer EM, Skiba M, Endermann T, Weisemann J, Stern D, Dorner MB, Finkenwirth F, Wolf J, Luginbühl W, Messelhäußer U, Bellanger L, Woudstra C, Rummel A, Fach P, Dorner BG

Detection, differentiation, and identification of botulinum neurotoxin serotypes C, CD, D, and DC by highly specific immunoassays and mass spectrometry

Analyst 2016; 141 (18): 5281 -5297
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Kutschenko A, Reinert MC, Krez N, Liebetanz D, Rummel A

BoNT/AB hybrid maintains similar duration of paresis as BoNT/A wild-type in murine running wheel assay

Netherlands : Elsevier B.V, NeuroToxicology 2016; 59: 1-8
Originalpublikation
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Reichert O, Fleming T, Neufang G, Schmelz M, Genth H, Kaever V, Wenck H, Stäb F, Terstegen L, Kolbe L, Roggenkamp D

Impaired glyoxalase activity is associated with reduced expression of neurotrophic factors and pro-inflammatory processes in diabetic skin cells

Denmark : John Wiley & Sons A/S. Published by John Wiley & Sons Ltd, Experimental Dermatology 2017; 26 (1): 44-50
Originalpublikation
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Schelle I, Bruening J, Buetepage M, Genth H

Role of p38alpha/beta MAP Kinase in Cell Susceptibility to Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B

Toxins (Basel) 2016; 9 (1), 2
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