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Paracelsus Medizinische Privatuniversität

 

 

 

Principal Investigator: Prof. Dirk Strunk/ PD Dr. Katharina Schallmoser      

 

Scientists: Patrizia Peking, PhD

 

 

 

 

Areas of expertise

 

- Translational cell therapy


- MSC transplantation (for GvHD, multiple sclerosis, vascular disease etc.)


- Clinical bone marrow, mobilized adult peripheral blood and neonatal umbilical cord transplantation

 

-Platelet biology and diagnostics


- Standard procedures for GMP-compliant large scale animal serum-free human mesenchymal stem cell (MSC) propagation

 

 

Main tasks

 

Work Package 7

 

- Advancing the processes for primary human MSC expansion:

GMP-grade, animal serum-free and safe propagation of human MSCs from various tissues with superior efficiency adapted to TECHNOBEAT requirements

 

- Providing fully characterized, animal serum-free MSCs of highest quality for advanced µ-tissue engineering and transplantation

 

- Elucidating mode of MSC action in conjunction with µ-tissues:

Analyzing protein production, secretion, metabolism and signaling of MSCs with particular focus on hypoxic conditions and on analysis of the secretome derived from µ-tissue cultures

 

Link:

http://www.pmu.ac.at