W. Wang, M. H. Gräler and E. J. Goetzl (2005): Type 4 sphingosine 1-phosphate G protein-coupled receptor (S1P4) transduces S1P effects on T cell proliferation and cytokine secretion without signaling migration. Faseb J online Jul 26.
M. H. Gräler, M. C. Huang, S. Watson and E. J. Goetzl (2005): Immunological effects of transgenic constitutive expression of the type 1 sphingosine 1-phosphate receptor by mouse lymphocytes. J Immunol 174: 1997-2003.
E. J. Goetzl, D. Dembrow, J. R. Van Brocklyn, M. Gräler and M. C. Huang (2004): An IgM-kappa rat monoclonal antibody specific for the type 1 sphingosine 1-phosphate G protein-coupled receptor with antagonist and agonist activities. Immunol Lett 93: 63-69.
E. J. Goetzl and M. H. Gräler (2004): Sphingosine 1-phosphate and its type 1 G protein-coupled receptor: trophic support and functional regulation of T lymphocytes. J Leukoc Biol 76: 30-35.
E. J. Goetzl, W. Wang, C. McGiffert, M. C. Huang and M. H. Gräler (2004): Sphingosine 1-phosphate and its G protein-coupled receptors constitute a multifunctional immunoregulatory system. J Cell Biochem 92: 1104-1114.
M. H. Gräler and E. J. Goetzl (2004): The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors. Faseb J 18: 551-553.
W. Wang, M. H. Gräler and E. J. Goetzl (2004): Physiological sphingosine 1-phosphate requirement for optimal activity of mouse CD4+ regulatory T Cells. Faseb J 18: 1043-1045.
G. Dorsam, M. H. Gräler, C. Seroogy, Y. Kong, J. K. Voice and E. J. Goetzl (2003): Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor. J Immunol 171: 3500-3507.
M. H. Gräler, R. Grosse, A. Kusch, E. Kremmer, T. Gudermann and M. Lipp (2003): The sphingosine 1-phosphate receptor S1P4 regulates cell shape and motility via coupling to Gi and G12/13. J Cell Biochem 89: 507-519.
M. H. Gräler, Y. Kong, J. S. Karliner and E. J. Goetzl (2003): Protein kinase C epsilon dependence of the recovery from down-regulation of S1P1 G protein-coupled receptors of T lymphocytes. J Biol Chem 278: 27737-27741.
E. J. Goetzl, M. Gräler, M. C. Huang and G. Shankar (2002): Lysophospholipid growth factors and their G protein-coupled receptors in immunity, coronary artery disease, and cancer. ScientificWorldJournal 2: 324-338.
M. Gräler and E. J. Goetzl (2002): Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells. Faseb J 16: 1874-1878.
M. Gräler, G. Shankar and E. J. Goetzl (2002): Cutting edge: suppression of T cell chemotaxis by sphingosine 1-phosphate. J Immunol 169: 4084-4087.
M. H. Gräler and E. J. Goetzl (2002): Lysophospholipids and their G protein-coupled receptors in inflammation and immunity. Biochim Biophys Acta 1582: 168-174.
M. C. Huang, M. Gräler, G. Shankar, J. Spencer and E. J. Goetzl (2002): Lysophospholipid mediators of immunity and neoplasia. Biochim Biophys Acta 1582: 161-167.
H. Lee, J. J. Liao, M. Gräler, M. C. Huang and E. J. Goetzl (2002): Lysophospholipid regulation of mononuclear phagocytes. Biochim Biophys Acta 1582: 175-177.
J. R. Van Brocklyn, M. H. Gräler, G. Bernhardt, J. P. Hobson, M. Lipp and S. Spiegel (2000): Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6. Blood 95: 2624-2629.
M. H. Gräler, G. Bernhardt and M. Lipp (1999): A lymphoid tissue-specific receptor, EDG6, with potential immune modulatory functions mediated by extracellular lysophospholipids. Curr Top Microbiol Immunol 246: 131-136; discussion 137.
M. H. Gräler, G. Bernhardt and M. Lipp (1998): EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue. Genomics 53: 164-169.
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