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Prof. Dr. rer. nat. Detlef Neumann

 

Institute of Pharmacology

 

E-Mail:

neumann.detlef@mh-hannover.de

 

Histamine, T cells, Dendritic Cells, Mucosal Immunology

 

Homepage (link):

www.mh-hannover.de/index.php

 

Synopsis

Histamine is a mediator of a large series of physiological and pathological processes. So far, four receptor subtypes selective for histamine are known, referred to as histamine H1-receptor (H1R), H2R, H3R and H4R. The H4R, identified in 2001, is expressed manly on cells of hematopoietic origin and provides a potential target for new anti-inflammatory therapeutic strategies. This role of the H4R in models of inflammatory diseases is investigated in our group.