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Publikationen

2017

Weber K, Lasch F, Koch A. New research strategy with ambiguous implications: A comment on 'Planning future studies based on the conditional power of a meta-analysis' , Statistics in Medicine, accepted, DOI: 10.1002/sim.7595.

 

Wacker ME, Kitzing K, Jörres RA, Leidl R, Schulz H, Karrasch S, Karch A, Koch A, Vogelmeier CF, Holle R. The contribution of symptoms and comorbidities to the economic impact of COPD: an analysis of the German COSYCONET cohort.  Int J Chron Obstruct Pulmon Dis. 2017 Dec 4;12:3437-3448. doi: 10.2147/COPD.S141852.



Smid DE, Franssen FME, Gonik M, Miravitlles M, Casanova C, Cosio BG, de Lucas-Ramos P, Marin JM, Martinez C, Mir I, Soriano JB, de Torres JP, Agusti A, Atalay NB, Billington J, Boutou AK, Brighenti-Zogg S, Chaplin E, Coster S, Dodd JW, Dürr S, Fernandez-Villar A, Groenen MTJ, Guimarães M, Hejduk K, Higgins V, Hopkinson NS, Horita N, Houben-Wilke S, Janssen DJA, Jehn M, Joerres R, Karch A, Kelly JL, Kim YI, Kimura H, Koblizek V, Kocks JH, Kon SSC, Kwon N, Ladeira I, Lee SD, Leuppi JD, Locantore N, Lopez-Campos JL, D-C Man W, Maricic L, Mendoza L, Miedinger D, Mihaltan F, Minami S, van der Molen T, Murrells TJ, Nakken N, Nishijima Y, Norman IJ, Novotna B, O'Donnell DE, Ogata Y, Pereira ED, Piercy J, Price D, Pothirat C, Raghavan N, Ringbaek T, Sajkov D, Sigari N, Singh S, Small M, da Silva GF, Tanner RJ, Tsiligianni IG, Tulek B, Tzanakis N, Vanfleteren LEGW, Watz H, Webb KA, Wouters EFM, Xie GG, Yoshikawa M, Spruit MA. Redefining Cut-Points for High Symptom Burden of the Global Initiative for Chronic Obstructive Lung Disease Classification in 18,577 Patients With Chronic Obstructive Pulmonary Disease. J Am Med Dir Assoc. 2017 Dec 1; 18(12):1097.e11-1097.e24. doi: 10.1016/j.jamda.2017.09.003.



Panzica M, Brandes J, Schmiddem U, Karch A, Hawi N, Krettek C, Meller R. Fatty degeneration of the deltoid muscle associated with displaced proximal humerus fractures. Technol Health Care. 25(5): 959-967. doi: 10.3233/THC-170834.



Fähndrich S, Biertz F, Karch A, Kleibrink B, Koch A, Teschler H, Welte T, Kauczor HU, Janciauskiene S, Jörres RA, Greulich T, Vogelmeier CF, Bals R, COSYCONET study group. Cardiovascular risk in patients with alpha-1-antitrypsin deficiency. Respir Res. 18(1): 171. doi: 10.1186/s12931-017-0655-1.

 

Hasford J, Koch A. Ethische Aspekte der klinischen Prüfung bei seltenen Erkrankungen. Bundesgesundheitsblatt (60), p. 556-562.

 

Mettke F, Schlevogt B, Deterding K, Wranke A, Smith A, Port K, Manns MP, Vogel A, Cornberg M, Wedemeyer H. Interferon-free therapy of chronic hepatitis C with direct-acting antivirals does not change the short-term risk for de novo hepatocellular carcinoma in patients with liver cirrhosis. Aliment Pharmacol Ther. 2017;00:1–10. doi.org/10.1111/apt.14427.

Haufe S, Wiechmann K, Stein L, Kueck M, Smith A, Meineke S, et al. Low-dose, non-supervised, health insurance initiated exercise for the treatment and prevention of chronic low back pain in employees. Results from a randomized controlled trial. PLoS ONE 12(6): e0178585. doi.org/10.1371/journal.pone.0178585.

Könneker S, Broelsch GF, Kuhbier JW, Framke T, Neubert N, Dastagir K, Mett T, Vogt PM, Jokuszies A. Outcome Analysis of End-to-End and End-to-Side Anastomoses in 131 Patients Undergoing Microsurgical Free Flap Reconstruction of the Lower Extremity. J Reconstr Microsurg Open 2017; 02(01): e7-e14, DOI: 10.1055/s-0036-1593815.


Keil C, Aguirre Dávila L, Framke T, Lenzen H, Manns MP, Lankisch TO, Voigtländer T. Patients with primary sclerosing cholangitis require more sedation during endoscopic retrograde cholangiography.  Endosc Int Open. 2017 Apr;5(4):E315-E320. doi: 10.1055/s-0043-104858.


Framke T. “Limonade und Schokolade – wie kann man Versuchsplanung versüßen?” In: Vonthein, R., Burkholder, I., Muche, R., Rauch, G. [Hrsg.] Zeig mir mehr Biostatistik! Mehr Ideen und neues Material für einen guten Biometrie-Unterricht, Springer Spektrum, 2017, S. 51-60, DOI: 10.1007/978-3-662-54825-7.

 

Gutberlet M, Kaireit TF, Voskrebenzev A, Lasch F, Freise J, Welte T, Wacker F, Hohlfeld JM, Vogel-Claussen J. Free-breathing Dynamic 19F Gas MR Imaging for Mapping of Regional Lung Ventilation in Patients with COPD. Radiology. 2017 Oct 3:170591. doi: 10.1148/radiol.2017170591. http://pubs.rsna.org/doi/10.1148/radiol.2017170591

 

Pietsch M, Aguirre Dávila L, Erfurt P, Avci E, Lenarz T, Kral A. Spiral Form of the Human Cochlea Results from Spatial Constraints. Sci Rep [Internet]. 2017;7(1):7500. Available from: http://www.nature.com/articles/s41598-017-07795-4.


Bavendiek U, Aguirre Davila L, Koch A, Bauersachs J. Assumption versus evidence: the case of digoxin in atrial fibrillation and heart failure. Eur Heart J [Internet]. 2017;0:1–5. Available from: academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehw577\nhttp://eurheartj.oxfordjournals.org/lookup/doi/10.1093/eurheartj/ehw577.

 

Spineli LM, Jenz E, Großhennig A, Koch A. Critical appraisal of arguments for the delayed-start design proposed as alternative to the parallel-group randomized clinical trial design in the field of rare disease. Orphanet J Rare Dis [Internet]. 2017;12(1):140. Available from: http://ojrd.biomedcentral.com/articles/10.1186/s13023-017-0692-3.


Hasford J, Koch A. Ethische Aspekte der klinischen Prüfung bei seltenen Erkrankungen. Bundesgesundheitsblatt - Gesundheitsforsch - Gesundheitsschutz [Internet]. 2017;60(5):556–62. Available from: http://link.springer.com/10.1007/s00103-017-2537-6.

 

Haeseler G, Schaefers D, Prison N, Ahrens J, Liu X, Karch A. Combatting pain after orthopedic/trauma surgery - perioperative oral extended-release tapentadol vs. extended-release oxycodone/naloxone. BMC Anesthesiol. 2017 Jul 11;17(1):91. doi: 10.1186/s12871-017-0383-6.

 

Lasch F, Weber K, Chao M M, Koch A. A plea to provide best evidence in trials under sample-size restrictions: the example of pioglitazone to resolve leukoplakia and erythroplakia in Fanconi anemia patients. Orphanet Journal of Rare Diseases 2017 12:102, DOI: 10.1186/s13023-017-0655-8

 

Karl FM, Holle R, Bals R, Greulich T, Jörres RA, Karch A, Koch A, Karrasch S, Leidl R, Schulz H, Vogelmeier C, Wacker ME, COSYCONET Study Group: Costs and health-related quality of life in Alpha-1-Antitrypsin Deficient COPD patients. Respir Res. 18(1):60. doi: 10.1186/s12931-017-0543-8.


Kaeding TS, Karch A, Schwarz R, Flor T, Wittke TC, Kück M, Böselt G, Tegtbur U, Stein L: Whole-body vibration training as a workplace-based sports activity for employees with chronic low-back pain. Scand J Med Sci Sports. 2017 Feb 10. doi: 10.1111/sms.12852. [Epub ahead of print]

2016

Houben-Wilke S, Jörres RA, Bals R, Franssen FM, Gläser S, Holle R, Karch A, Koch A, Magnussen H, Obst A, Schulz H, Spruit MA, Wacker ME, Welte T, Wouters EF, Vogelmeier C, Watz H: Peripheral Artery Disease and its Clinical Relevance in Patients with COPD in the COSYCONET Study. Am J Respir Crit Care Med. 2017 Jan 15;195(2):189-197. doi: 10.1164/rccm.201602-0354OC.


Jakubovski E, Reichert C, Karch A, Buddensiek N, Breuer D, Müller-Vahl K: The ONLINE-TICS Study Protocol: A Randomized Observer-Blind Clinical Trial to Demonstrate the Efficacy and Safety of Internet-Delivered Behavioral Treatment for Adults with Chronic Tic Disorders. Front Psychiatry; 7:119. doi: 10.3389/fpsyt.2016.00119.


Wacker ME, Jörres RA, Karch A, Koch A, Heinrich J, Karrasch S, Schulz H, Peters A, Gläser S, Ewert R, Baumeister SE, Vogelmeier C, Leidl R, Holle R; COSYCONET study group: Relative impact of COPD and comorbidities on generic health-related quality of life: a pooled analysis of the COSYCONET patient cohort and control subjects from the KORA and SHIP studies. Respir Res.; 17(1):81. doi: 10.1186/s12931-016-0401-0.


Karch A, Koch A, Grünwald V: A phase II trial comparing pazopanib with doxorubicin as first-line treatment in elderly patients with metastatic or advanced soft tissue sarcoma (EPAZ): study protocol for a randomized controlled trial. Trials; 17(1):312. doi: 10.1186/s13063-016-1434-x.


Chatzikyrkou C, Eichler J, Karch A, Clajus C, Scurt FG, Ramackers W, Lehner F, Menne J, Haller H, Mertens PR, Schiffer M: Short- and long-term effects of the use of RAAS blockers immediately after renal transplantation. Blood Press. 2016 May 19:1-9. [Epub ahead of print]


Wacker ME, Jörres RA, Karch A, Wilke S, Heinrich J, Karrasch S, Koch A, Schulz H, Watz H, Leidl R, Vogelmeier C, Holle R; COSYCONET-Consortium: Assessing health-related quality of life in COPD: comparing generic and disease-specific instruments with focus on comorbidities. BMC Pulm Med.; 16(1):70. doi: 10.1186/s12890-016-0238-9.


Karch A, Koch A, Zapf A, Zerr I, Karch A: Partial verification bias and incorporation bias affected accuracy estimates of diagnostic studies for biomarkers that were part of an existing composite gold standard. J Clin Epidemiol. 78:73-82. doi: 10.1016/j.jclinepi.2016.03.022.

Scheper V, Leifholz M, von der Leyen H, Keller M, Denkena U, Koch A, Karch A, Miller J, Lenarz T. ACEMg-mediated hearing preservation in cochlear implant patients receiving different electrode lengths (PROHEARING): study protocol for a randomized controlled trial. Trials. 2016; 17:394. DOI 10.1186/s13063-016-1526-7.

 

Karch A, Vogelmeier C, Welte T, Bals R, Kauczor HU, Biederer J, Heinrich J, Schulz H, Gläser S, Holle R, Watz H, Korn S, Adaskina N, Biertz F, Vogel C, Vestbo J, Wouters EFM, Rabe KF, Söhler S, Koch A, Jörres RA, for the COSYCONET Study Group. The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline. Respir.Med. 2016; 112(18-24). DOI 10.1016/j.rmed.2016.03.008

 

Hueper K, Khalifa AA, Bräsen JH, Vo Chieu VD, Gutberlet M, Wintterle S, Lehner F, Richter N, Peperhove M, Tewes S, Weber K, Haller H, Wacker F, Gwinner W, Gueler F, Hartung D. Diffusion-Weighted imaging and diffusion tensor imaging detect delayed graft function and correlate with allograft fibrosis in patients early after kidney transplantation. J.Magn.Reson.Imaging 2016; 44(1):112-121. DOI 10.1002/jmri.25158

 

Kammer J, Ziesing S, Aguirre Davila L, Bültmann E, Illsinger S, Das AM, Haffner D, Hartmann H. Neurological Manifestations of Mycoplasma pneumoniae Infection in Hospitalized Children and Their Long-Term Follow-Up. Neuropediatrics 2016; 47(5):308-317. DOI 10.1055/s-0036-1584325

 

Höhn M, von Jan U, Framke T, Albrecht UV. Classification of Health Related Applications. Stud.Health Technol.Inform. 2016; 226:139-142. DOI 10.3233/978-1-61499-664-4-139

 

Lenzen H, Musmann E, Kottas M, Schönemeier B, Köhnlein T, Manns MP, Lankisch TO. Acute gastrointestinal bleeding cases presenting to the emergency department are associated with age, sex and seasonal and circadian factors. Eur.J.Gastroenterol.Hepatol. 2017; 29(1):78-83. DOI 10.1097/MEG.0000000000000752

 

Leo F, Bartels S, Mägel L, Framke T, Büsche G, Jonigk D, Christgen M, Lehmann U, Kreipe H. Prognostic factors in the myoepithelial-like spindle cell type of metaplastic breast cancer. Virchows Arch. 2016; 469(2):191-201. DOI 10.1007/s00428-016-1950-9

 

Lueer K, Biller H, Casper A, Windt H, Mueller M, Badorrek P, Haefner D, Framke T, Koch A, Ziehr H, Krug N, Koch W, Hohlfeld JM. Safety, efficacy and repeatability of a novel house dust mite allergen challenge technique in the Fraunhofer allergen challenge chamber. Allergy 2016; 71(12):1693-1700. DOI 10.1111/all.12947

 

Paparoupa M, Spineli L, Framke T, Ho H, Schuppert F, Gillissen A. Pulmonary Embolism in Pneumonia: Still a Diagnostic Challenge? Results of a Case-Control Study in 100 Patients. Dis.Markers 2016; DOI 10.1155/2016/8682506

 

Rios N, Adaskina N, Frömke C, Papendorf F, Schippert C, Koch A, Hillemanns P, Park-Simon TW. The Benefit of Baseline Staging-Risk Assessment of Distant Breast Cancer Metastases by Tumor Stage.
Anticancer Res. 2016; 36(9):4909-4914

 

Derlin T, Thiele J, Weiberg D, Thackeray JT, Püschel K, Wester HJ, Aguirre Davila L, Larena-Avellaneda A, Daum G, Bengel FM, Schumacher U. Evaluation of 68Ga-Glutamate Carboxypeptidase II Ligand Positron Emission Tomography for Clinical Molecular Imaging of Atherosclerotic Plaque Neovascularization Arterioscler. Thromb.Vasc.Biol. 2016; 36(11):2213-2219. DOI 10.1161/ATVBAHA.116.307701

 

Klapdor R, Hillemanns P, Wölber L, Jückstock J, Hilpert F, de Gregorio N, Iborra S, Sehouli J, Habermann A, Fürst ST, Strauss HG, Baumann K, Thiel F, Mustea A, Meier W, Harter P, Wimberger P, Hanker L, Schmalfeldt B, Canzler U, Fehm T, Luyten A, Hellriegel M, Kosse J, Heiss C, Hantschmann P, Mallmann P, Tanner B, Pfisterer J, Richter B, Jäger M, Mahner S. Outcome After Sentinel Lymph Node Dissection in Vulvar Cancer: A Subgroup Analysis of the AGO-CaRE-1 Study. Ann.Surg.Oncol. 2016; DOI: 10.1245/s10434-016-5687-0

 

Lucke T, Herrera R, Wacker M, Holle R, Biertz F, Nowak D, Huber RM, Söhler S, Vogelmeier C, Ficker JH, Muckter H, Jörres RA, COSYCONET-Consortium. Systematic Analysis of Self-Reported Comorbidities in Large Cohort Studies - A Novel Stepwise Approach by Evaluation of Medication. PLoS One 2016; 11(10) DOI 10.1371/journal.pone.0163408

 

Bormann KH, Weber K, Kloppenburg H, Koch A, Meiser P, Gellrich NC. Perioperative Bromelain Therapy after Wisdom Teeth Extraction - A Randomized, Placebo-Controlled, Double-Blinded, Three-Armed, Cross-Over Dose-Finding Study. Phytother.Res. 2016; 30(12):2012-2019. DOI 10.1002/ptr.5707

 

Könneker S, Broelsch GF, Kuhbier JW, Framke T, Neubert N, Dastagir K, Mett T, Vogt PM, Jokuszies A. Outcome Analysis of End-to-End and End-to-Side Anastomoses in 131 Patients Undergoing Microsurgical Free Flap Reconstruction of the Lower Extremity. J Reconstr Microsurg Open 2016. DOI: 10.1055/s-0036-1593815

 

Neubert N, Vogt PM, May M, Boyce M, Koenneker S, Budde E, Jokuszies A. Does an Early and Aggressive Combined Wrapping and Dangling Procedure Affect the Clinical Outcome of Lower Extremity Free Flaps?-A Randomized Controlled Prospective Study Using Microdialysis Monitoring. J.Reconstr.Microsurg. 2016; 32(4):262-270. DOI 10.1055/s-0035-1568882

 

Deterding K, Spinner CD, Schott E, Welzel TM, Gerken G, Klinker H, Spengler U, Wiegand J, Zur Wiesch JS, Pathil A, Cornberg M, Umgelter A, Zöllner C, Zeuzem S, Papkalla A, Weber K, Hardtke S, von der Leyen H, Koch A, von Witzendorff D, Manns MP, Wedemeyer H, HepNet Acute HCV IV Study Group. Ledipasvir plus sofosbuvir fixed-dose combination for 6 weeks in patients with acute hepatitis C virus genotype 1 monoinfection (HepNet Acute HCV IV): an open-label, single-arm, phase 2 study. Lancet Infect.Dis. 2016. DOI:10.1016/S1473-3099(16)30408-X

 

Wranke A, Serrano BC, Heidrich B, Kirschner J, Bremer B, Lehmann P, Hardtke S, Deterding K, Port K, Westphal M, Manns MP, Cornberg M, Wedemeyer H. Antiviral treatment and liver-related complications in hepatitis delta Hepatology 2016. DOI:10.1002/hep.28876

 

 

2015

Doose M, Ziegenbein PD, Hoos O, Reim D, Stengert W, Hoffer N, Vogel C, Ziert Y, Sieberer M. Self-selected intensity exercise in the treatment of major depression: a pragmatic RCT. Int.J.Psychiatry Clin.Pract. 2015; 19(4):266-275.


Fischer F, Klapdor R, Gruessner S, Ziert Y, Hillemanns P, Hertel H. Radiofrequency endometrial ablation for the treatment of heavy menstrual bleeding among women at high surgical risk. Int.J.Gynaecol.Obstet. 2015; 131(2):123-128.


Gonnermann A, Kottas M, Koch A. Biometrische Entscheidungsunterstützung in Zulassung und Nutzenbewertung am Beispiel der Implikationen von heterogenen Ergebnissen in Untergruppen der Studienpopulation. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2015; 58(3):274-282.


Hille-Betz U, Vaske B, Bremer M, Soergel P, Kundu S, Klapdor R, Hillemanns P, Henkenberens C. Spätnebenwirkungen der Bestrahlung, kosmetisches Ergebnis und Schmerzen bei Brustkrebspatientinnen nach brusterhaltender Chirurgie und dreidimensionaler konformaler Strahlentherapie : Risikomodifizierende Faktoren. Strahlenther.Onkol. 2016; 192(1):8-16.


Hueper K, Gueler F, Bräsen JH, Gutberlet M, Jang MS, Lehner F, Richter N, Hanke N, Peperhove M, Martirosian P, Tewes S, Vo Chieu VD, Großhennig A, Haller H, Wacker F, Gwinner W, Hartung D. Functional MRI detects perfusion impairment in renal allografts with delayed graft function. Am.J.Physiol.Renal Physiol. 2015; 308(12):F1444-51.


Koletsi D, Spineli LM, Lempesi E, Pandis N. Risk of bias and magnitude of effect in orthodontic randomized controlled trials: a meta-epidemiological review. Eur.J.Orthod. 2015; DOI: 10.1093/ejo/cjv049-.
  

Pandis N, Spineli LM. Die Netzwerk-Metaanalyse in der Kieferorthopädie: Die nächste Ebene der Evidenzsynthese? Inf.Orthod.Kieferorthop. 2015; 47(1):57-59.
  

Rohde GG, Koch A, Welte T. ABACOPD study group ; Randomized double blind placebo-controlled study to demonstrate that antibiotics are not needed in moderate acute exacerbations of COPD--the ABACOPD study. BMC Pulm.Med. 2015; 15.


Spineli LM, Fleming PS, Pandis N. Addressing missing participant outcome data in dental clinical trials. J.Dent. 2015; 43(6):605-618.


Dressler N, Chandra A, Aguirre Davila L, Spineli LM, Schippert C, von Versen-Höynck F. BMI and season are associated with vitamin D deficiency in women with impaired fertility: a two-centre analysis. Arch.Gynecol.Obstet. 2015; DOI: 10.1007/s00404-015-3950-4.


Gonnermann A,  Budde E, Fytili P (2015): Wie finde ich den optimalen Cutpoint in SAS?. In Koch A, Minkenberg R (Hrsg.) KSFE 2015 - Proceedings der 19.Konferenz der SAS®-Anwender in Forschung und Entwicklung, ISBN 978-3-8440-3777-7, Seiten 51-62.


Hanke N, King BL, Vaske B, Haller H, Schiffer M. A Fluorescence-Based Assay for Proteinuria Screening in Larval Zebrafish (Danio rerio). Zebrafish 2015; 12(5):372-376.


Deterding K, Grüner N, Buggisch P, Galle PR, Spengler U, Hinrichsen H, Berg T, Potthoff A, Großhennig A, Koch A, Diepolder H, Lüth S, Feyerabend S, Jung MC, Rogalska-Taranta M, Schlaphoff V, Cornberg M, Manns MP, Wedemeyer H, Wiegand J. Hep-Net Acute HCV-III Study Group ; Symptoms of anxiety and depression are frequent in patients with acute hepatitis C and are not associated with disease severity. Eur.J.Gastroenterol.Hepatol. 2016; 28(2):187-192.


Tiddens HA, Stick SM, Wild JM, Ciet P, Parker GJ, Koch A, Vogel-Claussen J. Respiratory tract exacerbations revisited: ventilation, inflammation, perfusion, and structure (VIPS) monitoring to redefine treatment. Pediatr.Pulmonol. 2015; 50 Suppl 40(S57-65).


Flunkert K, Koch A. Allgemeine Grundlagen klinischer Studien. In: Fiedler C,‎ Raddatz B [Hrsg.] Study Nurse / Studienassistenz: Das Kompendium für die Weiterbildung und Praxis Taschenbuch – 7. August 2015, Springer 2015; 25-34.


Wacker ME., Jörres RA, Schulz H, Heinrich J, Karrasch S, Karch A, Koch A, Peters A, Leidl R, Vogelmeier C, Holle R, COSYCONET-Consortium. Direct and indirect costs of COPD and its comorbidities: Results from the German COSYCONET study. Respir.Med. 2016; 111(39-46).
 

Lingner H, Großhennig A, Flunkert K, Buhr-Schinner H, Heitmann R, Tönnesmann U, van der Meyden J, Schultz K. ProKaSaRe Study Protocol: A Prospective Multicenter Study of Pulmonary Rehabilitation of Patients With Sarcoidosis. JMIR Res.Protoc. 2015; 4(4):e134.
 

Neubert N, Vogt PM., May M, Boyce M, Koenneker S, Budde E, Jokuszies A. Does an Early and Aggressive Combined Wrapping and Dangling Procedure Affect the Clinical Outcome of Lower Extremity Free Flaps?-A Randomized Controlled Prospective Study Using Microdialysis Monitoring. J.Reconstr.Microsurg. 2015; DOI: 10.1055/s-0035-1568882.
 
 
Schmiemann G, Blase L, Seeber C, Joos S, Steinhäuser J, Ernst S, Großhennig A, Hummers-Pradier E, Lingner H. Manual Therapy by General Medical Practitioners for Nonspecific Low Back Pain in Primary Care: The ManRuck Study Protocol of a Clinical Trial. J.Chiropr Med. 2015; 14(1):39-45.


Schwarz A, Linnenweber-Held S, Heim A, Framke T, Haller H, Schmitt C. Viral Origin, Clinical Course, and Renal Outcomes in Patients With BK Virus Infection After Living-Donor Renal Transplantation. Transplantation 2015; DOI: 10.1097/TP.0000000000001066.


Volk V, Schneider A, Spineli LM, Großhennig A, Stripecke R. The gender gap: discrepant human T-cell reconstitution after cord blood stem cell transplantation in humanized female and male mice. Bone Marrow Transplant. 2015; DOI: 10.1038/bmt.2015.290.


Weber K, Jäger M. Bayesianische Meta-Analyse mit PROC MCMC. 2015; 429-442.


Weissenborn K, Hecker H, Rückert N. Pitfalls in psychometric testing. Gastroenterology 2015; 148(3):664-665.


Engelmann C, Grote G, Miemietz B, Vaske B, Geyer S. Weggegangen - Platz vergangen?: Karriereaussichten universitären Gesundheitspersonals nach Rückkehr aus einer Elternzeit: Befragung und Beobachtungsstudie. Dtsch.Med.Wochenschr. 2015; 140(4):e28-e35.


Fengels H, Koegelenberg C, Irusen E, Bruwer J, Wilken E, Batubara E, Swart F, Gonnermann A, Welte T. The Effect of Pleural Drainage on Pulmonary Function Testing in Patients With Tuberculous Pleural Effusions.Pleura 2015; 2.


Schäfer T, Klintschar M, Lichtinghagen R, Plagemann I, Smith A, Budde E, Hagemeier L. Xanthochromia of the skull bone associated with HbA1c. Forensic Sci.Int. 2016; 260(54-58).


Rahman A, Meyer K, Oehler-Rahman K, Schwarz C, Vaske B, Günay H. Wahrnehmung von zahnmedizinischen Frühpräventionskonzepten - Welche Rolle kann die Hebamme übernehmen? Eine empirische Studie. DZZ 2016; 71(1):51-58.

Zapf A, Gwinner W, Karch A, Metzger J, Haller H, Koch A. Non-invasive diagnosis of acute rejection in renal transplant patients using mass spectrometry of urine samples - a multicentre phase 3 diagnostic accuracy study. BMC Nephrol. 16(153).

 

Werfel T, Heratizadeh A, Niebuhr M, Kapp A, Roesner LM, Karch A, Erpenbeck VJ, Lösche C, Jung T, Krug N, Badorrek P, Hohlfeld JM. Exacerbation of atopic dermatitis on grass pollen exposure in an environmental challenge chamber. J Allergy Clin Immunol. 136(1): 96-103.

 

Adaskina N, Flor T, Flunkert K, Lê MT. Grenzen verschieben - Tabellenausgabe mit ODS RTF und ODS TAGSETS.RTF. In Koch A, Minkenberg R (Hrsg.)  KSFE 2015 - Proceedings der 19.Konferenz der SAS®-Anwender in Forschung und Entwicklung, ISBN 978-3-8440-3777-7, Seiten 1 - 14.

 

Hong B, Biertz F, Raab P, Scheinichen D, Ertl P, Großhennig A, Nakamura M, Hermann EJ, Lang JM, Lanfermann H, Krauss J. Normobaric hyperoxia for treatment of pneumocephalus after posterior fossa surgery in the semisitting position: a prospective randomized controlled trial. PLoS One. 2015 May 20;10(5):e0125710. doi: 10.1371/journal.pone.0125710. eCollection 2015.

 

Koch A, Ziert Y. Does it help that efficacy has been proven once we start discussing (added) benefit? Biometrical Journal 00 (2015) 0, 1–15 DOI: 10.1002/bimj.201400017.

 

Gonnermann A, Framke T, Großhennig A and Koch A. No solution yet for combining two independent studies in the presence of heterogeneity, Statistics in Medicine, 34 (16) pp. 2476-2480, DOI: 10.1002/sim.6473.

 

Heidrich B, Cordes HJ, Klinker H, Möller B, Naumann U, Rössle M, Kraus MR, Böker KH, Roggel C,Schuchmann M, Stoehr A, Trein A, Hardtke S, Gonnermann A, Koch A, Wedemeyer H, Manns MP, Cornberg M. Treatment Extension of Pegylated Interferon Alpha and Ribavirin Does Not Improve SVR in Patients  with Genotypes 2/3 without Rapid Virological Response (OPTEX Trial): A Prospective, Randomized, Two-Arm, Multicentre Phase IV Clinical Trial. PLOS ONE June 9, 2015. doi:10.1371/journal.pone.0128069.

 

Budde S, Noll Y, Zieglschmid V, Schroeder C, Koch A, Windhagen H. Determination of the efficacy of EVICEL™ on blood loss in orthopaedic surgery after total knee replacement: study protocol for a randomised controlled trial. Trials 2015, 16:299  doi:10.1186/s13063-015-0822-y.

 

Gonnermann A, von Jan U, Albrecht UV. Draft Guideline for the Development of Evidence Based Medicine-Related Apps. Stud Health Technol Inform. 2015; 210:637-41.  doi:10.3233/978-1-61499-512-8-637.

 

Karch A, Hermann P, Ponto C, Schmitz M, Arora A, Zafar S, Llorens F, Müller-Heine A, Zerr I. Cerebrospinal fluid tau levels are a marker for molecular subtype in sporadic Creutzfeldt-Jakob disease. Neurobiol Aging. doi: 10.1016/j.neurobiolaging.2015.01.021.

 

Grünwald V, Keilholz U, Boehm A, Guntinas-Lichius O, Hennemann B, Schmoll HJ, Ivanyi P, Abbas M, Lehmann U, Koch A, Karch A, Zörner A, Gauler TC. TEMHEAD: a single-arm multicentre phase II study of temsirolimus in platin- and cetuximab refractory recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN) of the German SCCHN Group (AIO). Ann Oncol. 26(3):561-7.

 

Schober T, Framke T, Großhennig A, Klein C, Kreipe H, Maecker-Kolhoff B. CD30 in pediatric post-transplant lymphoproliferative disease after solid organ transplant: characterization of a new therapeutic target. Leuk Lymphoma 56(3): 832-3.

 

Tiede A, Klamroth R, Scharf RE, Trappe RU, Holstein K, Huth-Kühne A, Gottstein S, Geisen U, Schenk J, Scholz U, Schilling K, Neumeister P, Miesbach W, Manner D, Greil R, von Auer C, Krause M, Leimkühler K, Kalus U, Blumtritt JM, Werwitzke S, Budde E, Koch A, Knöbl P. Prognostic factors for remission of and survival in acquired hemophilia A (AHA): results from the GTH-AH 01/2010 study. Blood. 2015 Feb 12; 125(7): 1091–1097.

2014

Ahlenstiel-Grunow T, Koch A, Großhennig A, Frömke C, Sester M, Sester U, Schröder C, Pape L. A multicenter, randomized, open-labeled study to steer immunosuppressive and antiviral therapy by measurement of virus (CMV, ADV, HSV)-specific T cells in addition to determination of trough levels of immunosuppressants in pediatric kidney allograft recipients (IVIST01-trial): study protocol for a randomized controlled trial. Trials 2014;15:324-6215-15-324- IF 2,117

Behrens K, Del Pozo MA, Großhennig A, Sieberer M, Graef-Calliess IT. How much orientation towards the host culture is healthy? Acculturation style as risk enhancement for depressive symptoms in immigrants. Int J Soc Psychiatry 2014:DOI: 10.1177/0020764014560356- IF 1,333

Broccoli G, Vaske B, Müller L, Kahmann R, Isenberg J. Grenzen der arthroskopischen Behandlung degenerativer Läsionen des ulnokarpalen Komplexes in Abhängigkeit der Ulnavarianz Handchir Mikrochir Plast Chir 2014;46(3):151-162- IF 0,544

Calle Serrano B, Großhennig A, Homs M, Heidrich B, Erhardt A, Deterding K, Jaroszewicz J, Bremer B, Koch A, Cornberg M, Manns MP, Buti M, Wedemeyer H. Development and evaluation of a baseline-event-anticipation score for hepatitis delta. J Viral Hepat 2014;21(11):e154-63- IF 3,307

Dingemann C, Meyer A, Kircher G, Boemers TM, Vaske B, Till H, Ure BM. Long-term health-related quality of life after complex and/or complicated esophageal atresia in adults and children registered in a German patient support group. J Pediatr Surg 2014;49(4):631-638- IF 1,311

Dubrowinskaja N, Gebauer K, Peters I, Hennenlotter J, Abbas M, Scherer R, Tezval H, Merseburger AS, Stenzl A, Grünwald V, Kuczyk MA, Serth J. Neurofilament Heavy polypeptide CpG island methylation associates with prognosis of renal cell carcinoma and prediction of antivascular endothelial growth factor therapy response. Cancer Med 2014;3(2):300-309

Eberhard J, Stiesch M, Kerling A, Bara C, Eulert C, Hilfiker-Kleiner D, Hilfiker A, Budde E, Bauersachs J, Kuck M, Haverich A, Melk A, Tegtbur U. Moderate and severe periodontitis are independent risk factors associated with low cardiorespiratory fitness in sedentary non-smoking men aged between 45 and 65 years. J Clin Periodontol 2014;41(1):31-37- IF 3,610

Framke T. Erhöhen Youtube-Videos auch Deinen Puls? . In: Rauch G, Muche R, Vonthein R [Hrsg.]: Zeig mir Biostatistik! Ideen und Material für einen guten Biometrie-Unterricht. Berlin u.a.: Springer Spektrum, 2014. (Springer-Lehrbuch). S. 25-34


Gillmann HJ, Meinders A, Großhennig A, Larmann J, Bünte C, Calmer S, Sahlmann B, Rustum S, Aper T, Lichtinghagen R, Koch A, Teebken OE, Theilmeier G. Perioperative levels and changes of high-sensitivity troponin T are associated with cardiovascular events in vascular surgery patients. Crit Care Med 2014;42(6):1498-1506- IF 6,147

Gonnermann A, Kottas M, Koch A. Biometrische Entscheidungsunterstützung in Zulassung und Nutzenbewertung am Beispiel der Implikationen von heterogenen Ergebnissen in Untergruppen der Studienpopulation Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2015:DOI: 10.1007/s00103-014-2105-2- IF 1,006

Hartmann H, Hawellek N, Wedekin M, Vogel C, Das AM, Balonwu K, Ehrich JH, Haffner D, Pape L. Early kidney transplantation improves neurocognitive outcome in patients with severe congenital chronic kidney disease. Transpl Int 2015:DOI: 10.1111/tri.12510- IF 3,120

Hille-Betz U, Vaske B, Henseler H, Soergel P, Kundu S, Makowski L, Schelcher S, Wojcinski S, Hillemanns P. Dermoglandular Rotation Flaps for Breast-Conserving Therapy: Aesthetic Results, Patient Satisfaction, and Morbidity in Comparison to Standard Segmentectomy. Int J Breast Cancer 2014;2014:152451

Kanzelmeyer NK, Pape L, Chobanyan-Jürgens K, Tsikas D, Hartmann H, Fuchs AJ, Vaske B, Das AM, Haubitz M, Jordan J, Lücke T. L-arginine/NO pathway is altered in children with haemolytic-uraemic syndrome (HUS). Oxid Med Cell Longev 2014;2014:203512- IF 3,363

Kreuzer M, Prüfe J, Bethe D, Vogel C, Großhennig A, Koch A, Oldhafer M, Dierks ML, Albrecht UV, Müther S, Brunkhorst R, Pape L. The TRANSNephro-study examining a new transition model for post-kidney transplant adolescents and an analysis of the present health care: study protocol for a randomized controlled trial. Trials 2014;15(1):505- IF 2,117

Kustikova OS, Stahlhut M, Ha TC, Scherer R, Schambach A, Baum C. Dose response and clonal variability of lentiviral tetracycline-regulated vectors in murine hematopoietic cells. Exp Hematol 2014;42(7):505-515.e7- IF 2,806

Lingner H, Ernst S, Groβhennig A, Djahangiri N, Scheub D, Wittmann M, Schultz K. Asthma Control and Health related Quality of Life one year after inpatient pulmonary rehabilitation: the ProKAR Study. J Asthma 2014:1-27- IF 1,828

Manolis E, Koch A, Deforce D, Vamvakas S. The European Medicines Agency experience with biomarker qualification Methods Mol Biol 2015;1243:255-272

Mayorandan S, Meyer U, Gokcay G, Segarra N, de Baulny H, van Spronsen F, Zeman J, de Laet C, Spiekerkoetter U, Thimm E, Maiorana A, Dionisi-Vici C, Moeslinger D, Brunner-Krainz M, Lotz-Havla A, Cocho de Juan J, Couce Pico M, Santer R, Scholl-Bürgi S, Mandel H, Bliksrud Y, Freisinger P, Aldamiz-Echevarria L, Hochuli M, Gautschi M, Endig J, Jordan J, McKiernan P, Ernst S, Morlot S, Vogel A, Sander J, Das A. Cross-sectional study of 168 patients with hepatorenal tyrosinaemia and implications for clinical practice. Orphanet J Rare Dis 2014;9(1):107- IF 3,958

Mücke J, Klapdor R, Schneider M, Länger F, Gratz KF, Hillemanns P, Hertel H. Isthmocervical labelling and SPECT/CT for optimized sentinel detection in endometrial cancer: Technique, experience and results. Gynecol Oncol 2014;134(2):287-292- IF 3,687

Peters I, Dubrowinskaja N, Abbas M, Seidel C, Kogosov M, Scherer R, Gebauer K, Merseburger AS, Kuczyk MA, Grünwald V, Serth J. DNA methylation biomarkers predict progression-free and overall survival of metastatic renal cell cancer (mRCC) treated with antiangiogenic therapies. PLoS One 2014;9(3):e91440- IF 3,534

Peters I, Dubrowinskaja N, Kogosov M, Abbas M, Hennenlotter J, von Klot C, Merseburger AS, Stenzl A, Scherer R, Kuczyk MA, Serth J. Decreased GATA5 mRNA expression associates with CpG island methylation and shortened recurrence-free survival in clear cell renal cell carcinoma. BMC Cancer 2014;14:101-2407-14-101- IF 3,319

Peters I, Dubrowinskaja N, Tezval H, Kramer MW, von Klot CA, Hennenlotter J, Stenzl A, Scherer R, Kuczyk MA, Serth J. Decreased mRNA expression of GATA1 and GATA2 is associated with tumor aggressiveness and poor outcome in clear cell renal cell carcinoma. Target Oncol 2014:DOI: 10.1007/s11523-014-0335-8- IF 3,458

Peters I, Gebauer K, Dubrowinskaja N, Atschekzei F, Kramer MW, Hennenlotter J, Tezval H, Abbas M, Scherer R, Merseburger AS, Stenzl A, Kuczyk MA, Serth J. GATA5 CpG island hypermethylation is an independent predictor for poor clinical outcome in renal cell carcinoma. Oncol Rep 2014;31(4):1523-1530- IF 2,191

Schaumann F, Frömke C, Dijkstra D, Alessandrini F, Windt H, Karg E, Müller M, Winkler C, Braun A, Koch A, Hohlfeld J, Behrendt H, Schmid O, Koch W, Schulz H, Krug N. Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: results of a double-blinded randomized cross-over clinical pilot study. Part Fibre Toxicol 2014;11(1):39- IF 6,987
Schaumann S, Staufenbiel I, Scherer R, Schilhabel M, Winkel A, Stumpp SN, Eberhard J, Stiesch M. Pyrosequencing of supra- and subgingival biofilms from inflamed peri-implant and periodontal sites. BMC Oral Health 2014;14(1):157- IF 1,147

Schrem H, Platsakis AL, Kaltenborn A, Koch A, Metz C, Barthold M, Krauth C, Amelung V, Braun F, Becker T, Klempnauer J, Reichert B. Value and limitations of the BAR-score for donor allocation in liver transplantation. Langenbecks Arch Surg 2014;399(8):1011-1019- IF 2,160

Schröder M, Stüber V, Walendzik E, O'Loughlin PF, Zapf A, Krettek C, Gaulke R. Establishing an optimal trajectory for calcaneotibial K-wire fixation in emergent treatment of unstable ankle fractures. Technol Health Care 2014:DOI: 10.3233/THC-140885- IF 0,636

Schroeder C, Heusser K, Zoerner AA, Grosshennig A, Wenzel D, May M, Sweep FC, Mehling H, Luft FC, Tank J, Jordan J. Pacemaker current inhibition in experimental human cardiac sympathetic activation: a double-blind, randomized, crossover study. Clin Pharmacol Ther 2014;95(6):601-607- IF 7,390

Teschner H, Vaske B, Albrecht UV, Meller R, Liodakis E, Wiebking U, Krettek C, Jagodzinski M. Conversion of hemi into reverse shoulder arthroplasty: implant design limitations. Arch Orthop Trauma Surg 2014;134(12):1683-1689- IF 1,310

Ünlü N, Meyer K, Müller-Heine A, Adaskina N, Geurtsen W, Günay H. Mundgesundheit bei Frauen im Alter von 16 bis 34 Jahren mit Migrationshintergrund sowie ihrer Lebenspartner. DZZ 2014;69(1):25-34

von Klot CA, Kramer MW, Peters I, Hennenlotter J, Abbas M, Scherer R, Herrmann TR, Stenzl A, Kuczyk MA, Serth J, Merseburger AS. Galectin-1 and Galectin-3 mRNA expression in renal cell carcinoma. BMC Clin Pathol 2014;14:15-6890-14-15. eCollection 2014

Wonnemann M, Frömke C, Koch A. Inflation of the type I error: investigations on regulatory recommendations for bioequivalence of highly variable drugs. Pharm Res 2015;32(1):135-143- IF 3,976

Wranke A, Heidrich B, Ernst S, Calle Serrano B, Caruntu FA, Curescu MG, Yalcin K, Gürel S, Zeuzem S, Erhardt A, Lüth S, Papatheodoridis GV, Bremer B, Stift J, Grabowski J, Kirschner J, Port K, Cornberg M, Falk CS, Dienes HP, Hardtke S, Manns MP, Yurdaydin C, Wedemeyer H, HIDIT-2 Study Group. Anti-HDV IgM as a marker of disease activity in hepatitis delta. PLoS One 2014;9(7):e101002- IF 3,534


Zeckey C, Wendt K, Mommsen P, Winkelmann M, Frömke C, Weidemann J, Stübig T, Krettek C, Hildebrand F. Kinetic therapy in multiple trauma patients with severe blunt chest trauma: An analysis at a level-1 trauma center. Technol Health Care 2014:DOI: 10.3233/THC-140869- IF 0,636

Schober T, Framke T, Großhennig A, Klein C, Kreipe H, Maecker-Kolhoff B. CD30 in pediatric post-transplant lymphoproliferative disease after solid organ transplant: characterization of a new therapeutic target. Leuk Lymphoma 2014:DOI: 10.3109/10428194.2014.941837- IF 2,605(Letter)

Gillmann HJ, Meinders A, Großhennig A, Larmann J, Bünte C, Calmer S, Sahlmann B, Rustum S, Aper T, Lichtinghagen R, Koch A, Teebken OE, Theilmeier G. The authors reply. Crit Care Med 2014;42(9):e632-3- IF 6,147(Comment)

2013

Danne T, Kaltheuner M, Koch A, Ernst S, Rathmann W, Rüssmann HJ, Bramlage P, DIVE Studiengruppe. Diabetes Versorgungs-Evaluation (DIVE) - eine nationale Initiative zur Qualitätssicherung in der diabetologischen Versorgung. Dtsch Med Wochenschr 2013;138(18):934-939- IF 0,656

Das AM, Goedecke K, Meyer U, Kanzelmeyer N, Koch S, Illsinger S, Lücke T, Hartmann H, Lange K, Lanfermann H, Hoy L, Ding XQ. Dietary Habits and Metabolic Control in Adolescents and Young Adults with Phenylketonuria: Self-Imposed Protein Restriction May Be Harmful. JIMD Rep 2014;13:149-158

Deterding K, Grüner N, Buggisch P, Wiegand J, Galle PR, Spengler U, Hinrichsen H, Berg T, Potthoff A, Malek N, Großhennig A, Koch A, Diepolder H, Lüth S, Feyerabend S, Jung MC, Rogalska-Taranta M, Schlaphoff V, Cornberg M, Manns MP, Wedemeyer H, Hep-Net Acute HCV-III Study Group. Delayed versus immediate treatment for patients with acute hepatitis C: a randomised controlled non-inferiority trial. Lancet Infect Dis 2013;13(6):497-506- IF 19,966

Eberhard J, Grote K, Luchtefeld M, Heuer W, Schuett H, Divchev D, Scherer R, Schmitz-Streit R, Langfeldt D, Stumpp N, Staufenbiel I, Schieffer B, Stiesch M. Experimental gingivitis induces systemic inflammatory markers in young healthy individuals: a single-subject interventional study. PLoS One 2013;8(2):e55265- IF 3,730

Flor T, Adaskina N, Koch A. Medizinische Dokumentation und Biometrie als Partner bei der Durchführung qualitativ hochwertiger klinischer Studien. MDI : Forum der Medizin-Dokumentation und Medizin-Informatik 2013;15(1):4-8

Gebauer K, Peters I, Dubrowinskaja N, Hennenlotter J, Abbas M, Scherer R, Tezval H, Merseburger AS, Stenzl A, Kuczyk MA, Serth J. Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma. Br J Cancer 2013;108(1):131-138- IF 5,082

Giesemann AM, Raab P, Lyutenski S, Dettmer S, Bultmann E, Frömke C, Lenarz T, Lanfermann H, Goetz F. Improved imaging of Cochlear nerve hypoplasia using a 3-tesla variable flip-angle turbo spin-echo sequence and a 7-cm surface coil. Laryngoscope 2014;124(3):751-754- IF 1,979

Goldschmidt I, Streckenbach C, Dingemann C, Pfister ED, di Nanni A, Zapf A, Baumann U. Application and limitations of transient liver elastography in children. J Pediatr Gastroenterol Nutr 2013;57(1):109-113- IF 2,196

Grischke J, Müller-Heine A, Hülsmann M. The effect of four different irrigation systems in the removal of a root canal sealer. Clin Oral Investig 2014;18(7):1845-1851- IF 2,200

Gross MM, Frömke C, Hecker H. The timing of amniotomy, oxytocin and neuraxial analgesia and its association with labour duration and mode of birth. Arch Gynecol Obstet 2014;289(1):41-48- IF 1,330

Großhennig A, Benda N, Koch A. Die Bedeutung von Biomarkern für eine personalisierte Medizin. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2013;56(11):1480-1488- IF 0,722

Heidrich MB, Wenzel D, von Kaisenberg CS, Schippert C, von Versen-Höynck FM. Preeclampsia and long-term risk of cardiovascular disease: what do obstetrician-gynecologists know? BMC Pregnancy Childbirth 2013;13:61-2393-13-61- IF 2,516

Hertel H, Soergel P, Muecke J, Schneider M, Papendorf F, Laenger F, Gratz KF, Hillemanns P. Is there a place for sentinel technique in treatment of vaginal cancer?: feasibility, clinical experience, and results. Int J Gynecol Cancer 2013;23(9):1692-1698- IF 1,941
Jessen F, Wolfsgruber S, Wiese B, Bickel H, Mösch E, Kaduszkiewicz H, Pentzek M, Riedel-Heller SG, Luck T, Fuchs A, Weyerer S, Werle J, van den Bussche H, Scherer M, Maier W, Wagner M, German Study on Aging, Cognition and Dementia in Primary Care Patients. AD dementia risk in late MCI, in early MCI, and in subjective memory impairment. Alzheimers Dement 2014;10(1):76-83- IF 14,483

Kaiser O, Paasche G, Stöver T, Ernst S, Lenarz T, Kral A, Warnecke A. TGF-beta superfamily member activin A acts with BDNF and erythropoietin to improve survival of spiral ganglion neurons in vitro. Neuropharmacology 2013;75:416-425- IF 4,114


Klingmann V, Spomer N, Lerch C, Stoltenberg I, Frömke C, Bosse HM, Breitkreutz J, Meissner T. Favorable acceptance of mini-tablets compared with syrup: a randomized controlled trial in infants and preschool children. J Pediatr 2013;163(6):1728-1732.e1- IF 4,035

Koch A, Framke T. Reliably basing conclusions on subgroups of randomized clinical trials. J Biopharm Stat 2014;24(1):42-57- IF 0,728

Köhne CH, Bedenne L, Carrato A, Bouche O, Popov I, Gaspa L, Valladares M, Rougier P, Gog C, Reichardt P, Wils J, Pignatti F, Biertz F. A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study. Eur J Cancer 2013;49(8):1868-1875- IF 5,061

Krämer S, Meyer H, O'Loughlin PF, Vaske B, Krettek C, Gaulke R. The incidence of ulnocarpal complaints after distal radial fracture in relation to the fracture of the ulnar styloid. J Hand Surg Eur Vol 2013;38(7):710-717- IF 1,171

Meyer H, Krämer S, O'Loughlin PF, Vaske B, Krettek C, Gaulke R. Union of the ulnar styloid fracture as a function of fracture morphology on conventional radiographs. Skeletal Radiol 2013;42(8):1135-1141- IF 1,741

Mynarek M, Ganzenmueller T, Mueller-Heine A, Mielke C, Gonnermann A, Beier R, Sauer M, Eiz-Vesper B, Kohstall U, Sykora KW, Heim A, Maecker-Kolhoff B. Patient, Virus, and Treatment-Related Risk Factors in Pediatric Adenovirus Infection after Stem Cell Transplantation: Results of a Routine Monitoring Program. Biol Blood Marrow Transplant 2014;20(2):250-256- IF 3,940

Pferdmenges DC, Baumann U, Müller-Heine A, Framke T, Pfister ED. Prognostic marker for liver disease due to alpha1-antitrypsin deficiency. Klin Pädiatr 2013;225(5):257-262- IF 1,904

Rodt T, Luepke M, Boehm C, Hueper K, Halter R, Glage S, Hoy L, Wacker F, Borlak J, von Falck C. Combined Micro-PET/Micro-CT Imaging of Lung Tumours in SPC-raf and SPC-myc Transgenic Mice. PLoS One 2012;7(9):e44427- IF 4,092

Rodt T, von Falck C, Dettmer S, Hueper K, Halter R, Hoy L, Luepke M, Borlak J, Wacker F. Lung tumour growth kinetics in SPC-c-Raf-1-BB transgenic mice assessed by longitudinal in-vivo micro-CT quantification. J Exp Clin Cancer Res 2012;31:15- IF 2,148

Schober T, Framke T, Kreipe H, Schulz TF, Großhennig A, Hussein K, Baumann U, Pape L, Schubert S, Wingen AM, Jack T, Koch A, Klein C, Maecker-Kolhoff B. Characteristics of Early and Late PTLD Development in Pediatric Solid Organ Transplant Recipients. Transplantation 2013;95(1):240-246- IF 4,003

Stoetzer M, Nickel F, Rana M, Lemound J, Wenzel D, von See C, Gellrich NC. Advances in assessing the volume of odontogenic cysts and tumors in the mandible: a retrospective clinical trial. Head Face Med 2013;9:14-160X-9-14- IF 0,981

Wang S-, Brannath W, Brückner M, James Hung HM, Koch A. Unblinded Adaptive Statistical Information Design Based on Clinical Endpoint or Biomarker. Statistics in biopharmaceutical research 2013;5(4):293-310- IF 0,511

Weinspach K, Staufenbiel I, Memenga-Nicksch S, Ernst S, Geurtsen W, Günay H. Level of information about the relationship between diabetes mellitus and periodontitis - results from a nationwide diabetes information program. Eur J Med Res 2013;18(1):6- IF 1,098

Wenzel D, Zapf A. Difference of two dependent sensitivities and specificities: Comparison of various approaches. Biom J 2013;55(5):705-718- IF 1,152

Westhoff-Bleck M, Podewski E, Tutarel O, Wenzel D, Cappello C, Bertram H, Bauersachs J, Widder J. Prognostic value of NT-proBNP in patients with systemic morphological right ventricles: a single-centre experience. Int J Cardiol 2013;169(6):433-438- IF 5,509

Westhoff-Bleck M, Schieffer B, Tegtbur U, Meyer GP, Hoy L, Schaefer A, Tallone EM, Tutarel O, Mertins R, Wilmink LM, Anker SD, Bauersachs J, Roentgen P. Aerobic training in adults after atrial switch procedure for transposition of the great arteries improves exercise capacity without impairing systemic right ventricular function. Int J Cardiol 2013;170(1):24-29- IF 5,509


2012

Andruszkow H, Frink M, Frömke C, Matityahu A, Zeckey C, Mommsen P, Suntardjo S, Krettek C, Hildebrand F. Tip apex distance, hip screw placement, and neck shaft angle as potential risk factors for cut-out failure of hip screws after surgical treatment of intertrochanteric fractures. Int Orthop 2012;36(11):2347-2354- IF 2,025

Atschekzei F, Hennenlotter J, Jänisch S, Großhennig A, Tränkenschuh W, Waalkes S, Peters I, Dörk T, Merseburger AS, Stenzl A, Kuczyk MA, Serth J. SFRP1 CpG island methylation locus is associated with renal cell cancer susceptibility and disease recurrence. Epigenetics 2012;7(5):447-457- IF 4,318


Berktold L, V Kaisenberg C, Hillemanns P, Vaske B, Schmidt P. Analysis of the impact of PAPP-A, free beta-hCG and nuchal translucency thickness on the advanced first trimester screening. Arch Gynecol Obstet 2013;287(3):413-420- IF 1,277

Eggers H, Steffens S, Großhennig A, Becker JU, Hennenlotter J, Stenzl A, Merseburger AS, Kuczyk MA, Serth J. Prognostic and diagnostic relevance of hypermethylated in cancer 1 (HIC1) CpG island methylation in renal cell carcinoma. Int J Oncol 2012;40(5):1650-1658- IF 2,399

Frömke C, Hothorn LA, Sczesny F, Onken J, Schneider M. Analytical method transfer: Improving interpretability with ratio-based statistical approaches. J Pharm Biomed Anal 2013;74:186-193- IF 2,967

Hueper K, Zapf A, Skrok J, Pinheiro A, Goldstein TA, Zheng J, Zimmerman SL, Kamel IR, Abraham R, Wacker F, Bluemke DA, Abraham T, Vogel-Claussen J. In Hypertrophic Cardiomyopathy Reduction of Relative Resting Myocardial Blood Flow Is Related to Late Enhancement, T2-Signal and LV Wall Thickness. PLoS One 2012;7(7):e41974- IF 4,092

Jack T, Boehne M, Brent BE, Hoy L, Köditz H, Wessel A, Sasse M. In-line filtration reduces severe complications and length of stay on pediatric intensive care unit: a prospective, randomized, controlled trial. Intensive Care Med 2012;38(6):1008-1016- IF 5,399

Jokuszies A, Radtke C, Herold C, Vaske B, Vogt P. A survey of anticoagulation practice among German speaking microsurgeons – Perioperative management of anticoagulant therapy in free flap surgery. GMS Ger Plast Reconstr Aesthet Surg 2012;2:Doc03

Knüppel M, Kubicka S, Vogel A, Malek NP, Schneider M, Papendorf F, Greten T, Wedemeyer J, Schneider A. Combination of conservative and interventional therapy strategies for intra- and extrahepatic cholangiocellular carcinoma: a retrospective survival analysis. Gastroenterol Res Pract 2012;2012:190708- IF 0,978

Körner S, Kollewe K, Ilsemann J, Müller-Heine A, Dengler R, Krampfl K, Petri S. Prevalence and prognostic impact of comorbidities in Amyotrophic Lateral Sclerosis. Eur J Neurol 2013;20(4):647-654- IF 3,692

Körner S, Siniawski M, Kollewe K, Rath KJ, Krampfl K, Zapf A, Dengler R, Petri S. Speech therapy and communication device: Impact on quality of life and mood in patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener 2013;14(1):20-25

Krämer S, Meyer H, O'Loughlin PF, Vaske B, Krettek C, Gaulke R. The incidence of ulnocarpal complaints after distal radial fracture in relation to the fracture of the ulnar styloid. J Hand Surg Eur Vol 2013;38(7):710-717- IF 1,171

May M, Mand P, Biertz F, Hummers-Pradier E, Kruschinski C. A survey to assess family physicians' motivation to teach undergraduates in their practices. PLoS One 2012;7(9):e45846- IF 4,092

Mederacke I, Yurdaydin C, Großhennig A, Erhardt A, Cakaloglu Y, Yalcin K, Gurel S, Zeuzem S, Zachou K, Chatzikyrkou C, Bozkaya H, Dalekos GN, Manns MP, Wedemeyer H, Hep-Net/International Delta Hepatitis Study Group. Renal function during treatment with adefovir plus peginterferon alfa-2a vs either drug alone in hepatitis B/D co-infection. J Viral Hepat 2012;19(6):387-395- IF 4,088

Mommsen P, Zeckey C, Andruszkow H, Weidemann J, Frömke C, Puljic P, van Griensven M, Frink M, Krettek C, Hildebrand F. Comparison of Different Thoracic Trauma Scoring Systems in Regards to Prediction of Post-Traumatic Complications and Outcome in Blunt Chest Trauma. J Surg Res 2012;176(1):239-247- IF 2,239

Pape L, Ahlenstiel T, Werner CD, Zapf A. Development and validation of a new statistical model for prognosis of long-term graft function after pediatric kidney transplantation. Pediatr Nephrol 2013;28(3):499-505- IF 2,518

Peters I, Eggers H, Atschekzei F, Hennenlotter J, Waalkes S, Tränkenschuh W, Großhennig A, Merseburger AS, Stenzl A, Kuczyk MA, Serth J. GATA5 CpG island methylation in renal cell cancer: a potential biomarker for metastasis and disease progression. BJU Int 2012;110(2 Pt B):E144-52- IF 2,844

Rana M, Zapf A, Kuehle M, Gellrich NC, Eckardt AM. Clinical evaluation of an autofluorescence diagnostic device for oral cancer detection: a prospective randomized diagnostic study. Eur J Cancer Prev 2012;21(5):460-466- IF 2,130

Reifenrath H, Wacker FK, Alten T, Müller-Heine A, Tecklenburg A. Analyse der Arbeitsabläufe eines radiologischen Zentrums mittels Multimoment-Häufigkeits-Studie: Methodische Grundlagen. Röfo 2012;184(12):1110-1117- IF 2,758

Rodt T, Luepke M, Boehm C, Hueper K, Halter R, Glage S, Hoy L, Wacker F, Borlak J, von Falck C. Combined Micro-PET/Micro-CT Imaging of Lung Tumours in SPC-raf and SPC-myc Transgenic Mice. PLoS One 2012;7(9):e44427- IF 4,092

Rodt T, von Falck C, Dettmer S, Hueper K, Halter R, Hoy L, Luepke M, Borlak J, Wacker F. Lung tumour growth kinetics in SPC-c-Raf-1-BB transgenic mice assessed by longitudinal in-vivo micro-CT quantification. J Exp Clin Cancer Res 2012;31:15- IF 2,148

Schiffer L, Schiffer M, Merkel S, Schwarz A, Mengel M, Jürgens C, Schroeder C, Zoerner AA, Püllmann K, Bröcker V, Becker JU, Dämmrich ME, Träder J, Grosshennig A, Biertz F, Haller H, Koch A, Gwinner W. Rationale and design of the RIACT--study: a multi-center placebo controlled double blind study to test the efficacy of RItuximab in Acute Cellular tubulointerstitial rejection with B-cell infiltrates in renal Transplant patients: study protocol for a randomized controlled trial. Trials 2012;13(1):199- IF 2,496

Schmidt P, Hörmansdorfer C, Vaske B, Hillemanns P, Scharf A. Aneuploidy screening during pregnancy by a three-dimensional Advanced First Trimester Screening model: Description of the AFS-3D algorithm. Prenat Diagn 2012;32(2):154-159- IF 2,106

Schneider M, Frömke C, Menold E, Bärtsch P. Evaluation der universitären sportmedizinischen Einrichtungen in Deutschland. Deutsche Zeitschrift fur Sportmedizin 2012;63(2):46-52- IF 0,429

Schober T, Framke T, Kreipe H, Schulz TF, Großhennig A, Hussein K, Baumann U, Pape L, Schubert S, Wingen AM, Jack T, Koch A, Klein C, Maecker-Kolhoff B. Characteristics of Early and Late PTLD Development in Pediatric Solid Organ Transplant Recipients. Transplantation 2013;95(1):240-246- IF 4,003

Schwarz A, Linnenweber-Held S, Heim A, Bröcker V, Rieck D, Framke T, Raggub L, Haller H. Factors influencing viral clearing and renal function during polyomavirus BK-associated nephropathy after renal transplantation. Transplantation 2012;94(4):396-402- IF 4,003

Steiert A, Reimers K, Burke W, Zapf A, Vogt P. Covalent vectored binding of functional proteins by bifunctional crosslinking at silicone interfaces. J Biomed Mater Res A 2012;100(5):1248-1255- IF 2,625

Tünsmeyer J, Vaske B, Bösing B, Kästner SB. Cardiovascular effects of a proprietary l-methadone/fenpipramide combination (Polamivet) alone and in addition to acepromazine in healthy Beagle dogs. Vet Anaesth Analg 2012;39(5):451-463- IF 0,944

Wahl K, Rosenberg W, Vaske B, Manns MP, Schulze-Osthoff K, Bahr MJ, Bantel H. Biopsy-Controlled Liver Fibrosis Staging Using the Enhanced Liver Fibrosis (ELF) Score Compared to Transient Elastography. PLoS One 2012;7(12):e51906- IF 4,092

Westhaus S, Bankwitz D, Ernst S, Rohrmann K, Wappler I, Agne C, Luchtefeld M, Schieffer B, Sarrazin C, Manns MP, Pietschmann T, Ciesek S, von Hahn T. Characterization of the inhibition of hepatitis C virus entry by in vitro generated and patient derived oxidized low density lipoprotein. Hepatology 2013;57(5):1716-1724- IF 11,665

Ziegler A, Koch A, Krockenberger K, Grosshennig A. Personalized medicine using DNA biomarkers: a review. Hum Genet 2012;131(10):1627-1638- IF 5,069

Isaac M, Pani L, Gispen-de Wied C, Koch A. European licensing of maintenance treatment in schizophrenia. Lancet 2012;380(9841):562-563- IF 38,278(Letter)


2011

Adaskina N, Biertz F. CRF-Gestaltung, Grenzen und Möglichkeiten der elektronischen CRFs. MDI 2011(3):133-137


Agustian PA, Schiffer M, Gwinner W, Schäfer I, Theophile K, Modde F, Bockmeyer CL, Traeder J, Lehmann U, Großhennig A, Kreipe HH, Bröcker V, Becker JU. Diminished met signaling in podocytes contributes to the development of podocytopenia in transplant glomerulopathy. Am J Pathol 2011;178(5):2007-2019- IF 5,224


Barkhausen T, Tschernig T, Rosenstiel P, van Griensven M, Vonberg RP, Dorsch M, Mueller-Heine A, Chalaris A, Scheller J, Rose-John S, Seegert D, Krettek C, Waetzig GH. Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model*. Crit Care Med 2011;39(6):1407-1413- IF 6,254

Bohnhorst B, Lange M, Bartels DB, Bejo L, Hoy L, Peter C. Procalcitonin and valuable clinical symptoms in the early detection of neonatal late-onset bacterial infection. Acta Paediatr 2012;101(1):19-25- IF 1,955

Chobanyan-Jürgens K, Fuchs AJ, Tsikas D, Kanzelmeyer N, Das AM, Illsinger S, Vaske B, Jordan J, Lücke T. Increased asymmetric dimethylarginine (ADMA) dimethylaminohydrolase (DDAH) activity in childhood hypercholesterolemia type II. Amino Acids 2012;43(2):805-811- IF 4,106

Damm F, Heuser M, Morgan M, Wagner K, Görlich K, Großhennig A, Hamwi I, Thol F, Surdziel E, Fiedler W, Lübbert M, Kanz L, Reuter C, Heil G, Delwel R, Löwenberg B, Valk PJ, Krauter J, Ganser A. Integrative prognostic risk score in acute myeloid leukemia with normal karyotype. Blood 2011;117(17):4561-4568- IF 10,558

Donnerstag F, Ding X, Pape L, Bültmann E, Lücke T, Zajaczek J, Hoy L, Das AM, Lanfermann H, Ehrich J, Hartmann H. Patterns in early diffusion-weighted MRI in children with haemolytic uraemic syndrome and CNS involvement. Eur Radiol 2012;22(3):506-513- IF 3,594

Drebenstedt S, Zapf A, Rödig T, Mausberg R, Ziebolz D. Efficacy of Two Different CHX-Containing Desensitizers: A Controlled Double-Blind Study. Oper Dent 2012;37(2):161-171- IF 1,560

Fricke-Zech S, Gruber RM, Dullin C, Zapf A, Kramer FJ, Kubein-Meesenburg D, Hahn W. Measurement of the midpalatal suture width. Angle Orthod 2012;82(1):145-150- IF 1,000

Großhennig A. Genetisch-epidemiologische Methoden zur Analyse komplexer kardiovaskulärer Phänotypen. Lübeck: Zentrale Hochschulbibliothek Lübeck, 2011

Illsinger S, Goken C, Brockmann M, Thiemann I, Bednarczyk J, Schmidt KH, Lücke T, Hoy L, Janzen N, Das AM. Effect of tacrolimus on energy metabolism in human umbilical endothelial cells. Ann Transplant 2011;16(2):68-75- IF 0,975

Illsinger S, Janzen N, Sander S, Bode J, Mallunat L, Thomasmeyer R, Hagebölling F, Schmidt KH, Bednarczyk J, Vaske B, Lücke T, Das AM. Energy metabolism in umbilical endothelial cells from preterm and term neonates. J Perinat Med 2011;39(5):587-593- IF 1,871

Jäger MD, Kaaden S, Emmanouilidis N, Lück R, Beckmann JH, Güner Z, Kespohl H, Glockzin K, Aselmann H, Kaudel CP, Schwarz A, Zapf A, Klempnauer J, Scheumann GF. Effect of incomplete parathyroidectomy preserving entire parathyroid glands on renal graft function. Arch Surg 2011;146(6):704-710- IF 4,500

Javaher P, Stuhrmann M, Wilke C, Frenzel E, Manukjan G, Großhennig A, Dechend F, Schwaab E, Schmidtke J, Schubert S. Should TSPYL1 mutation screening be included in routine diagnostics of male idiopathic infertility? Fertil Steril 2012;97(2):402-406- IF 3,958

Joka D, Wahl K, Moeller S, Schlue J, Vaske B, Bahr MJ, Manns MP, Schulze-Osthoff K, Bantel H. Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and nonalcoholic steatohepatitis. Hepatology 2012;55(2):455-464- IF 10,885

Kanzelmeyer N, Tsikas D, Chobanyan-Jurgens K, Beckmann B, Vaske B, Illsinger S, Das AM, Lücke T. Asymmetric dimethylarginine in children with homocystinuria or phenylketonuria. Amino Acids 2012;42(5):1765-1772- IF 4,106

Khaladj N, Peterss S, Pichlmaier M, Shrestha M, von Wasielewski R, Hoy L, Haverich A, Hagl C. The impact of deep and moderate body temperatures on end-organ function during hypothermic circulatory arrest. Eur J Cardiothorac Surg 2011;40(6):1492-1499- IF 2,293

Knüppel M, Kubicka S, Vogel A, Malek NP, Schneider M, Papendorf F, Greten T, Wedemeyer J, Schneider A. Combination of conservative and interventional therapy strategies for intra- and extrahepatic cholangiocellular carcinoma: a retrospective survival analysis. Gastroenterol Res Pract 2012;2012:190708- IF 0,978

Koch A. Nutzen und Schaden - zwei Seiten derselben Münze? Z Evid Fortbild Qual Gesundhwes 2011;105(3):163-170

Körner S, Kollewe K, Fahlbusch M, Zapf A, Dengler R, Krampfl K, Petri S. Onset and spreading patterns of upper and lower motor neuron symptoms in amyotrophic lateral sclerosis. Muscle Nerve 2011;43(5):636-642- IF 2,302

Kulik U, Framke T, Großhennig A, Ceylan A, Bektas H, Klempnauer J, Lehner F. Liver Resection of Colorectal Liver Metastases in Elderly Patients. World J Surg 2011;35(9):2063-2072- IF 2,693

Mommsen P, Andruszkow H, Frömke C, Zeckey C, Wagner U, van Griensven M, Frink M, Krettek C, Hildebrand F. Effects of accidental hypothermia on posttraumatic complications and outcome in multiple trauma patients. Injury 2013;44(1):86-90- IF 2,269

Mommsen P, Zeckey C, Andruszkow H, Weidemann J, Frömke C, Puljic P, van Griensven M, Frink M, Krettek C, Hildebrand F. Comparison of Different Thoracic Trauma Scoring Systems in Regards to Prediction of Post-Traumatic Complications and Outcome in Blunt Chest Trauma. J Surg Res 2012;176(1):239-247- IF 2,239

Otto N, Manukjan G, Göhring G, Hofmann W, Scherer R, Luna JC, Lehmann U, Ganser A, Welte K, Schlegelberger B, Steinemann D. ICSBP promoter methylation in myelodysplastic syndromes and acute myeloid leukaemia. Leukemia 2011;25(7):1202-1207- IF 8,966

Redlich K, Khaladj N, Peterss S, Pichlmaier M, Shrestha M, Hoy L, Haverich A, Hagl C. Conventional aortic valve replacement in patients with concomitant coronary artery disease and previous coronary artery bypass grafting in the era of interventional approaches. Eur J Cardiothorac Surg 2011;40(2):455-462- IF 2,293

Reichelt A, Zeckey C, Hildebrand F, Großhennig A, Shin HO, Galanski M, Keberle M. Imaging of the brain in polytraumatized patients comparing 64-row spiral CT with incremental (sequential) CT. Eur J Radiol 2012;81(4):789-793- IF 2,941

Rödig T, Hirschleb M, Zapf A, Hülsmann M. Comparison of ultrasonic irrigation and RinsEndo for the removal of calcium hydroxide and Ledermix paste from root canals. Int Endod J 2011;44(12):1155-1161- IF 2,383

Tank J, Biller H, Heusser K, Holz O, Diedrich A, Framke T, Koch A, Großhennig A, Koch W, Krug N, Jordan J, Hohlfeld JM. Effect of acute ozone induced airway inflammation on human sympathetic nerve traffic: a randomized, placebo controlled, crossover study. PLoS One 2011;6(4):e18737- IF 4,411

Vosskuhl K, Negm AA, Framke T, Weismüller T, Manns MP, Wedemeyer H, Plentz RR, Wedemeyer J, Lankisch TO. Measurement of IgG4 in bile: a new approach for the diagnosis of IgG4-associated cholangiopathy. Endoscopy 2012;44(1):48-52- IF 6,096

Wedemeyer H, Yurdaydin C, Dalekos GN, Erhardt A, Cakaloglu Y, Degertekin H, Gurel S, Zeuzem S, Zachou K, Bozkaya H, Koch A, Bock T, Dienes HP, Manns MP, HIDIT Study Group. Peginterferon plus adefovir versus either drug alone for hepatitis delta. N Engl J Med 2011;364(4):322-331- IF 53,484

Ziebolz D, Stühmer C, Hornecker E, Zapf A, Mausberg RF, Chenot JF. Oral health in adult patients with congenital coagulation disorders--a case control study. Haemophilia 2011;17(3):527-531- IF 2,364

Großhennig A, Framke T, Koch A. Now: Prediction intervals - was I2 really an advantage? BMJ 2011;342(d549)- IF 13,471(Letter)