Department of Clinical Immunology & Rheumatology
Innate immunity, autoimmunity, immunodeficiency, NK cells
Natural killer (NK) cells comprise about 10-15% of the peripheral lymphocytes in human blood. NK cells are part of the innate immune system as they are able to spontaneously lyse tumors and virus-infected cells. In contrast to cells of adaptive immunity, such as B and T cells, they do not require prior sensitization. In addition to their cytolytic function NK cells are capable to produce several cytokines for regulating immune functions.