Institute of Infection Immunology, Twincore, Centre for Experimental and Clinical Infection Research
T cells, intestinal immune system, infection, inflammation
The immune system of the gut faces a great challenge: it has to guarantee for the integrity of the host tissue, without compromising the ability to develop tolerance against harmless foodborne antigens and the beneficial intestinal microbiota. In addition, the intestinal immune system must be able to mount a rapid and effective response to pathogens, in order to protect the host from harmful gastro-intestinal infections. It is the main focus of our lab to study the mechanisms that are responsible for the induction and regulation of inflammatory immune responses during intestinal infection and inflammation.