Institute of Immunology
Ig-like cell surface receptors, NK cells, T cells and NKT cells, adaptive immune response
We discovered that CD155 plays a non-redundant role in modulating gut humoral immune response in mice. Since then, it was shown that the CD155/ligand-system is involved in many immunologically relevant processes such as cytotoxic T cell mediated killing of target cells, CD4 T cell activation, or manipulation of NK cell activity. In our group, we currently investigate how CD155 and its ligand impact on development and function of follicular helper T and NKT cells.