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2014

Olling A, Hüls C, Goy S, Müller M, Krooss S, Rudolf I, Tatge H, Gerhard R.

The combined repetitive oligopeptides of clostridium difficile toxin A counteract premature cleavage of the glucosyl-transferase domain by stabilizing protein conformation.

Toxins (Basel) 2014;6(7):2162-2176- IF 2,480
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Lee K, Lam KH, Kruel AM, Perry K, Rummel A, Jin R.

High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex.

Biochem Biophys Res Commun 2014;446(2):568-573- IF 2,281
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Lee K, Zhong X, Gu S, Kruel AM, Dorner MB, Perry K, Rummel A, Dong M, Jin R.

Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex.

Science 2014;344(6190):1405-1410- IF 31,477
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Wohlan K, Goy S, Olling A, Srivaratharajan S, Tatge H, Genth H, Gerhard R.

Pyknotic cell death induced by Clostridium difficile TcdB: Chromatin condensation and nuclear blister are induced independently of the glucosyltransferase activity.

Cell Microbiol 2014;76(11):1678-1692- IF 4,816
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Strotmeier J, Mahrhold S, Krez N, Janzen C, Lou J, Marks JD, Binz T, Rummel A.

Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A.

FEBS Lett 2014;588(7):1087-1093- IF 3,341
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Hardtke-Wolenski M, Taubert R, Noyan F, Sievers M, Dywicki J, Schlue J, Falk CS, Lundgren BA, Scott HS, Pich A, Anderson MS, Manns MP, Jaeckel E.

Autoimmune hepatitis in a murine APS-1 model is directed against multiple autoantigens.

Hepatology 2014- IF 11,190
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Matsui T, Gu S, Lam KH, Carter LG, Rummel A, Mathews II, Jin R.

Structural Basis of the pH-Dependent Assembly of a Botulinum Neurotoxin Complex.

J Mol Biol 2014;426(22):3773-3782- IF 3,959
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Jünger J, Just I.

Recommendations of the German Society for Medical Education and the German Association of Medical Faculties regarding university-specific assessments during the study of human, dental and veterinary medicine

GMS Z Med Ausbild 2014;31(3):Doc34
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Jochim N, Gerhard R, Just I, Pich A.

Time-resolved cellular effects induced by TcdA from Clostridium difficile.

Rapid Commun Mass Spectrom 2014;28(10):1089-1100- IF 2,642
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Rohrbeck A, Schröder A, Hagemann S, Pich A, Höltje M, Ahnert-Hilger G, Just I.

Vimentin mediates uptake of C3 exoenzyme.

PLoS One 2014;9(6):e101071- IF 3,534
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Rohrbeck A, von Elsner L, Hagemann S, Just I.

Binding of Clostridium botulinum C3 exoenzyme to intact cells.

Naunyn Schmiedebergs Arch Pharmacol 2014;387(6):523-532- IF 2,360
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Chatterji B, Dickhut C, Mielke S, Krüger J, Just I, Glage S, Meier M, Wedekind D, Pich A.

MALDI imaging mass spectrometry to investigate endogenous peptides in an animal model of Usher's disease.

Proteomics 2014;14(13-14):1674-1687- IF 3,973
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May M, Schelle I, Brakebusch C, Rottner K, Genth H.

Rac1-dependent recruitment of PAK2 to G2 phase centrosomes and their roles in the regulation of mitotic entry.

Cell Cycle 2014;13(14):2211-2221- IF 5,006
Link zum Abstract


Wagner S, Maibaum D, Pich A, Nolte I, Murua Escobar H.

Verification of a Canine PSMA (FolH1) Antibody.

Anticancer Res 2015;35(1):145-148- IF 1,872

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Genth H, Pauillac S, Schelle I, Bouvet P, Bouchier C, Varela-Chavez C, Just I, Popoff MR. Link zum Volltext

Haemorrhagic toxin and lethal toxin from Clostridium sordellii strain vpi9048: molecular characterization and comparative analysis of substrate specificity of the large clostridial glucosylating toxins.

Cell Microbiol 2014;16(11):1706-1721- IF 4,816

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Gonzalez-Escalona N, Thirunavukkarasu N, Singh A, Toro M, Brown EW, Zink D, Rummel A, Sharma SK. Link zum Volltext

Draft Genome Sequence of Bivalent Clostridium botulinum Strain IBCA10-7060, Encoding Botulinum Neurotoxin B and a New FA Mosaic Type.

Genome Announc 2014;2(6):10.1128/genomeA01275-14

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Nkuipou-Kenfack E, Koeck T, Mischak H, Pich A, Schanstra JP, Zürbig P, Schumacher B.

Proteome analysis in the assessment of ageing.

Ageing Res Rev 2014;18C:74-85- IF 7,628
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Balletta A, Lorenz D, Rummel A, Gerhard R, Bigalke H, Wegner F.

Clostridium difficile toxin B inhibits the secretory response of human mast cell line-1 (HMC-1) cells stimulated with high free-Ca and GTPgammaS.

Toxicology 2014;328C:48-56- IF 3,745
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Goy SD, Olling A, Neumann D, Pich A, Gerhard R.

Human neutrophils are activated by a peptide fragment of Clostridium difficile Toxin B presumably via formyl peptide receptor.

Cell Microbiol 2014:DOI: 10.1111/cmi.12410- IF 4,816
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Dressler D, Gessler F, Tacik P, Bigalke H.

An enzyme-linked immunosorbent assay for detection of botulinum toxin-antibodies.

Mov Disord 2014;29(10):1322-1324- IF 5,634
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Dressler D, Adib Saberi F, Bigalke H.

IncobotulinumtoxinA (Xeomin((R))) can produce antibody-induced therapy failure in a patient pretreated with abobotulinumtoxinA (Dysport((R))).

J Neural Transm 2014;121(7):769-771- IF 2,871
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Konze SA, van Diepen L, Schröder A, Olmer R, Moller H, Pich A, Weissmann R, Kuss AW, Zweigerdt R, Buettner FF.

Cleavage of E-cadherin and beta-catenin by calpain affects Wnt signaling and spheroid formation in suspension cultures of human pluripotent stem cells.

Mol Cell Proteomics 2014;13(4):990-1007- IF 7,254
Link zum Abstract