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Publications

 

Please click on the reference to link with PubMed.

 

Windheim, M. (2016) Interleukin-1-induced protein expression requires the membrane raft-dependent internalization of the interleukin-1 receptor. Cellular Signalling. doi: 10.1016/j.cellsig.2016.06.014

 

Windheim, M., Höning, S., Leppard, K.N., Butler, L., Seed. C., Ponnambalam, S., Burgert, H.G. (2016) Sorting motifs in the cytoplasmic tail of the immunomodulatory E3/49K protein of species D adenoviruses modulate cell surface expression and ectodomain shedding. Journal of Biological Chemistry. pii: jbc.M115.684787

 

Windheim, M., Hansen, B. (2014) Interleukin-1-induced activation of the small GTPase Rac1 depends on receptor internalization and regulates gene expression. Cellular Signalling 26: 49-55

 

Windheim, M., Southcombe, J.H. , Kremmer, E., Chaplin, L., Urlaub, D., Falk, C.S., Claus, M., Mihm, J., Braithwaite, M., Dennehy, K., Renz, H., Sester, M., Watzl, C., Burgert, H.-G. (2013) A unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions. Proceedings of the National Academy of Sciences of the United States of America 110: E4884-E4893

 

Hansen, B., Dittrich-Breiholz, O., Kracht, M., Windheim, M. (2013) Regulation of the NF-kappaB-dependent gene expression by ligand-induced endocytosis of the interleukin-1 receptor. Cellular Signalling 25: 214-228

 

Windheim, M., Peggie, M., Cohen, P. (2008) Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology. Biochemical Journal 409: 723-729

 

Ordureau, A., Smith, H., Windheim, M., Peggie, M., Carrick, E., Morrice, N., Cohen, P. (2008) The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1. Biochemical Journal 409: 43-52

 

Windheim, M., Stafford, M., Peggie, M., Cohen, P. (2008) Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase. Molecular and Cellular Biology 28: 1783-1791

 

Windheim, M., Lang, C., Peggie, M., Plater, L.A., Cohen, P. (2007) Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. Biochemical Journal 404: 179-190

 

Zhang, M., Windheim, M., Roe, M.S., Peggie, M., Cohen, P., Prodromou, C., Pearl, L.H. (2005) Chaperoned ubiquitylation - crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex. Molecular Cell 20: 525-538

 

Windheim, M., Hilgendorf, A., Burgert, H.-G. (2004) Immune evasion by adenovirus E3 proteins: Exploitation of intracellular trafficking pathways. Current Topics in Microbiology and Immunology 273: 29-85

 

Windheim, M., Burgert, H.-G. (2002) Characterization of E3/49K, a novel, highly glycosylated E3 protein of the epidemic keratoconjunctivitis-causing adenovirus type 19a. Journal of Virology 76: 755-66

 

Burgert, H.-G., Ruzsics, Z., Obermeier, S., Hilgendorf, A., Windheim, M., Elsing, A. (2002) Subversion of host defense mechanisms by adenoviruses. Current Topics in Microbiology and Immunology 269: 273-318

 

Blusch, J.H., Deryckere, F., Windheim, M., Ruzsics, Z., Arnberg, N., Adrian, T., Burgert, H.-G. (2002) E3/49K: A novel early region 3 protein specifically expressed by adenoviruses of subgenus D. Virology 296: 94-106


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