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Scherr M, Elder A, Battmer K, Barzan D, Bomken S, Ricke-Hoch M, Schröder A, Venturini L, Blair HJ, Vormoor J, Ottmann O, Ganser A, Pich A, Hilfiker-Kleiner D, Heidenreich O, Eder M.

Differential expression of miR-17~92 identifies BCL2 as a therapeutic target in BCR-ABL positive B-lineage acute lymphoblastic leukemia.

Leukemia 2014;28(3);554-565



Andruszkow H, Lefering R, Frink M, Mommsen P, Zeckey C, Rahe K, Krettek C, Hildebrand F.

Survival benefit of helicopter emergency medical services compared to ground emergency medical services in traumatized patients.

Crit Care 2013;17(3);R124



Bagramyan K, Kaplan BE, Cheng LW, Strotmeier J, Rummel A, Kalkum M.

Substrates and controls for the quantitative detection of active botulinum neurotoxin in protease-containing samples.

Anal Chem 2013;85(11);5569-5576



Balletta A, Lorenz D, Rummel A, Gerhard R, Bigalke H, Wegner F.

Human mast cell line-1 (HMC-1) cells exhibit a membrane capacitance increase when dialysed with high free-Ca(2+) and GTPgammaS containing intracellular solution.

Eur J Pharmacol 2013;720(1-3);227-236



Bigalke H.

Botulinum toxin: application, safety, and limitations.

Curr Top Microbiol Immunol 2013;364;307-317



Chatterji B, Pich A.

MALDI imaging mass spectrometry and analysis of endogenous peptides.

Expert Rev Proteomics 2013;10(4);381-388



Gerhard R, Frenzel E, Goy S, Olling A.

Cellular uptake of Clostridium difficile TcdA and truncated TcdA lacking the receptor binding domain.

J Med Microbiol 2013;62(9);1414-1422



Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.

Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.

Toxicon 2013;75C;108-121



Huelsenbeck SC, Roggenkamp D, May M, Huelsenbeck J, Brakebusch C, Rottner K, Ladwein M, Just I, Fritz G, Schmidt G, Genth H.

Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1.

Int J Biochem Cell Biol 2013;45(8);1767-1775



Lee K, Gu S, Jin L, Le TT, Cheng LW, Strotmeier J, Kruel AM, Yao G, Perry K, Rummel A, Jin R.

Structure of a bimodular botulinum neurotoxin complex provides insights into its oral toxicity.

PLoS Pathog 2013;9(10);e1003690



Mahrhold S, Strotmeier J, Garcia-Rodriguez C, Lou J, Marks JD, Rummel A, Binz T.

Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E.

Biochem J 2013;453(1);37-47



May M, Wang T, Müller M, Genth H.

Difference in F-actin depolymerization induced by toxin B from the Clostridium difficile strain VPI 10463 and toxin B from the variant Clostridium difficile serotype F strain 1470.

Toxins (Basel) 2013;5(1):106-119



Pirazzini M, Henke T, Rossetto O, Mahrhold S, Krez N, Rummel A, Montecucco C, Binz T.

Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain.

FEBS Lett 2013;587(23):3831-3836



Rangrez AY, Bernt A, Poyanmehr R, Harazin V, Boomgaarden I, Kuhn C, Rohrbeck A, Frank D, Frey N.

Dysbindin is a potent inducer of RhoA-SRF-mediated cardiomyocyte hypertrophy.

J Cell Biol 2013;203(4):643-656



Rummel A.

Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.

Curr Top Microbiol Immunol 2013;364;61-90


Schweer J, Kulkarni D, Kochut A, Pezoldt J, Pisano F, Pils MC, Genth H, Huehn J, Dersch P.

The Cytotoxic Necrotizing Factor of Yersinia pseudotuberculosis (CNFY) Enhances Inflammation and Yop Delivery during Infection by Activation of Rho GTPases.

PLoS Pathog 2013;9(11);e1003746



Steffen A, Ladwein M, Dimchev GA, Hein A, Schwenkmezger L, Arens S, Ladwein KI, Holleboom JM, Schur F, Small JV, Schwarz J, Gerhard R, Faix J, Stradal TE, Brakebusch C, Rottner K.

Rac function is critical for cell migration but not required for spreading and focal adhesion formation.

J Cell Sci 2013;126(Pt.20);4572-4588



Stevens GB, Silver DA, Zgaga-Griesz A, Bessler WG, Vashist SK, Patel P, Achazi K, Strotmeier J, Worbs S, Dorner MB, Dorner BG, Pauly D, Rummel A, Urban GA, Krueger M.

Bioluminescence assay for the highly sensitive detection of botulinum neurotoxin A activity.

Analyst 2013;138(20);6154-6162


Willjes G, Mahrhold S, Strotmeier J, Eichner T, Rummel A, Binz T.

Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity.

Biochemistry 2013;52(22);3930-3938



Zeiser J, Gerhard R, Just I, Pich A.

Substrate Specificity of Clostridial Glucosylating Toxins and Their Function on Colonocytes Analyzed by Proteomics Techniques.

J Proteome Res 2013;12(4);1604-1618