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Schadzek, P., Stahl, Y., Preller, M., Ngezahayo, A., Analysis of the dominant mutation N188T of human connexin46 (hCx46) using concatenation and molecular dynamics simulation. FEBS Open Bio. epub (2019).  DOI: 10.1002/2211-5463-12624.




Roberts, S., Seeger, M., Jiang, Y., Mishra, A., Sigmund, F., Stelzl, A., Lauri, A., Symvoulidis, P., Rolbieski, H., Preller, M., Deán-Ben, X.L., Razansky, D., Orschmann, T., Desbordes, S.C., Vetschera, P., Bach, T., Ntziachristos, V., Westmeyer, G.G.,

Calcium Sensor for Photoacoustic Imaging.
J. Am. Chem. Soc., 140, 2718-2721 (2018).



Beyer, U., Brand, F., Martens, H., Weder, J., Christians, A., Elyan, N., Hentschel, B., Westphal, M., Schackert, G., Pietsch, T., Hong, B., Krauss, J.K., Samii, A., Raab, P., Das, A., Dumitru, C.A., Sandalcioglu, I.E., Hakenberg, O.W., Erbersdobler, A., Lehmann, U., Reifenberger, G., Weller, M., Reijns, M.A.M., Preller, M., Wiese, B., Hartmann, C., Weber, R.G., Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis.
Acta Neuropathol. 134, 905-922 (2017).

Chinthalapudi, K., Heissler, S.M., Preller, M., Sellers, J.R., and Manstein, D.J.,
Mechanistic insights into the active site and allosteric communication pathways in human nonmuscle myosin-2C.
Elife 6, 10.7554/eLife.32742 (2017).

Mohammadi-Ostad-Kalayeh, S., Hrupins, V., Helmsen, S., Ahlbrecht, C., Stahl, F., Scheper, T., Preller, M., Surup, F., Stadler, M., Kirschning, A., and Zeilinger, C.,
Development of a microarray-based assay for efficient testing of new HSP70/DnaK inhibitors.
Bioorg. Med. Chem. 25, 6345-6352 (2017).

Osmanovic, A., Rangnau, I., Kosfeld, A., Abdulla, S., Janssen, C., Auber, B., Raab, P., Preller, M., Petri, S., and Weber, R.G. 
FIG4 variants in central European patients with amyotrophic lateral sclerosis: a whole-exome and targeted sequencing study.
Eur. J. Hum. Genet. 25, 324-331 (2017).

Preller, M. and Manstein, D.J.
Myosin Motors: Structural Aspects and Functionality.
Reference Module in Life Sciences (2017), Elsevier.



Schadzek, P., Schlingmann, B., Schaarschmidt, F., Lindner, J., Koval, M., Heisterkamp, A., Ngezahayo, A., and Preller, M.,
Data of the Molecular Dynamics Simulations of Mutations in the Human Connexin46 Docking Interface.
Data Brief 7, 93-99 (2016).

Schadzek, P., Schlingmann, B., Schaarschmidt, F., Lindner, J., Koval, M., Heisterkamp, A., Preller, M., and Ngezahayo, A.,
The Cataract Related Mutation N188T in Human Connexin46 (hCx46) Revealed a Critical Role for Residue N188 in the Docking Process of Gap Junction Channels.
Biochim. Biophys. Acta 1858, 57-66 (2016).

Schuster-Gossler, K., Cordes, R., Muller, J., Geffers, I., Delany-Heiken, P., Taft, M., Preller, M., and Gossler, A.,
Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.
Genetics 202, 1119-1133 (2016).



Diensthuber, R.P.; Tominaga, M.; Preller, M.; Hartmann, F.K.; Orii, H.; Chizhov, I.; Oiwa, K.; Tsiavaliaris, G.,
Kinetic Mechanism of Nicotiana Tabacum Myosin-11 Defines a New Type of Processive Motor.
doi: 10.1096/fj.14-254763



Hundt, N., Preller, M., Swolski, O., Ang, A.M., Mannherz, H.G., Manstein, D.J., and Müller, M.,
Molecular Mechanisms of Disease-Related Human Beta-Actin Mutations p.R183W and p.E364K.
FEBS J. 281, 5279-5291 (2014).


Martin, R.; Risacher, C.; Barthel, A.; Jäger, A.; Schmidt, A.W.; Richter, S.; Böhl, M.; Preller, M.; Chinthalapudi, K.; Manstein, D.J.; Gutzeit, H.O.; Knölker, H.-J.,
Silver(I)-Catalyzed Route to Pyrroles: Synthesis of Halogentated Pseudilins as Allosteric Inhibitors of Myosin ATPase and X-ray Crystal Structures of the Protein-Inhibitor Complexes.

Eur. J. Org. Chem.,


Radke, M.B.; Taft, M.H.; Stapel, B.; Hilfiker-Kleiner, D.; Preller, M.; Manstein, D.J.,
Small-Molecule-Mediated Refolding and Activation of Myosin Motor Function.
doi: 10.7554/eLife.01603.001




Preller, M., and D. J. Manstein (2013)
Myosin structure, allostery, and mechano-chemistry
Structure, doi: 10.1016/j.str.2013.09.015


Chaturvedi, A.; Araujo Cruz, M.M.; Jyotsana, N.; Sharma, A.; Yun, H.; Görlich, K.; Wichmann, M.; Schwarzer, A.; Preller, M.; Thol, F.; Meyer, J.; Haemmerle, R.; Struys, E.A.; Jansen, E.E., Modlich, U.; Li, Z.; Sly, L.M.; Geffers, R.; Lindner, R.; Manstein, D.J.; Lehmann, U.; Krauter, J.; Ganser, A.; Heuser, M.

Mutant IDH1 Promotes Leukemogenesis In Vivo and Can Be Specifically Targeted in Human AML.
Blood, doi: 10.1182/blood-2013-03-491571

Preller, M. and Holmes, K.C.,
The Myosin Start-of-Power Stroke State and How Actin Binding Drives the Power Stroke.
Cytoskeleton, doi: 10.1002/cm.21125

Müller, M.; Diensthuber, R.P.; Chizhov, I.; Claus, P.; Heissler, S.M.; Preller, M.; Taft, M.H.; Manstein, D.J.,
Distinct Functional Interactions between Actin Isoforms and Nonsarcomeric Myosins.
PLoS One, doi: 10.1371/journal.pone.0070636



Preller, M. and Manstein, D. J., Comprehensive Biophysics. Vol. 04.
Myosin Motors: Structural Aspects and Functionality
Academic Press, doi: 10.1016/B978-0-12-374920-8.00410-0



Preller, M.; Chinthalapudi, K.; Martin, R.; Knölker, H.-J.; Manstein, D. J.,
Inhibition of Myosin ATPase Activity by Halogenated Pseudilins: A Structure-Activity Study
J. Med. Chem., doi: 10.1021/jm200259f

Preller, M.; Bauer, S.; Adamek, N.; Fujita-Becker, S.; Fedorov, R.; Geeves, M. A.; Manstein, D. J.,
Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V.
J. Biol. Chem.
, doi: 10.1074/jbc.M111.265298


Chinthalapudi, K.; Taft, M. H.; Martin, R.; Heissler, S. M.; Preller, M.; Hartmann, F. K.; Brandstaetter, H.; Kendrick-Jones, J.; Tsiavaliaris, G.; Gutzeit, H. O.; Fedorov, R.; Buss, F.; Knölker, H.-J.; Coluccio, L. M.; Manstein, D. J.,
Mechanism and Specificity of Pentachloropseudilin-Mediated Inhibition of Myosin Motor Activity.
J. Biol. Chem.,
doi: 10.1074/jbc.M111.239210


Preller, M.; Grunenberg, J.; Bulychev, V. P.; Bulanin, M. O.,
Calculation of the Structure, Potential Energy Surface, Vibrational Dynamics, and Electric Dipole Properties for the Xe:HI van der Waals Complex.
J. Chem. Phys., doi: 10.1063/1.3583817



Heuser, M., Chaturvedi, A., Preller, M.,
Means and Methods for Treating Cancer,
EP 2996692 A2 (2016).

Preller, M.; Kalesse, M.; Manstein D. J.,
Novel Means and Methods for Treating Malaria and Other Parasitic Disorders,
EP 2727911 B1 (2016).

Preller, M., Furch, M., Díaz-Gómez, N., Kalesse, M., Manstein D. J.,
Biphenyl Compounds For Use In Treating Malaria and Other Parasitic Disorders,
US 9499471 B2 (2016).