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German Centre for Lung Research (DZL)



 DZL - Biobanking in Hannover


Biobanks as a part of the German Centre for Lung Research (DZL: Deutsches Zentrum für Lungenforschung) analyze, store and administrate biomaterial samples from clinic practice and research by using standardized conditions.

MHH has established a centralized, harmonized, modern, unified biobank called Hannover Unified Biobank (HUB), which compiles and realizes high biobanking standards for the DZL site Hannover. Until mid of 2014 HUB was located at the MHH campus in the Pediatric Research Center (PFZ). In May 2014 HUB moved to new Clinical Research Center (CRC) building which is located on the campus of the neighbouring Fraunhofer campus (ITEM). Through the involvement of HUB, DZL site Hannover stands for high quality and high sample safety and security standards.

Standardized biobanking on all DZL sites allows high quality and safety storage of biological material. Biological material from clinic and research will be analyzed, stored and administrated in respective biobanks. The DZL biobank platform unifies the biobanks of DZL und follows the aim to register and interconnect all the biobanks and make them accessible to DZL research projects.

Furthermore, a DZL biobanking portal has been established, which interlinks DZL members and ís connected with common internet catalogs like the German biobanking register (Deutsches Biobankenregister). In addition the biobank platform of DZL reached the harmonization of biological sample collections in the DZL biobanks. In focus of interest are harmonization and unification of strict Standard Operating Procedures (SOPs) and further guidance of biobanking regarding ethics, data protection and quality management in addition to harmonization of clinical phenotyping tools.



DZL in Hannover

In November 2011 Hannover was chosen from the Federal Ministry of Education and Research (BMBF) as one of five sites of the German Centre for Lung Research (DZL) in Germany. As network with the name BREATH, Hannover Medical School (MHH) applied together with the Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM) and the Leibniz Universität Hannover to the BMBF and convinced with their concept. (BREATH: Biomedical Research in Endstage And ObsTructive Lung Disease Hannover)


Further information of German Centre for Lung Research (DZL):



General information about DZL

Diseases of the lung belong to the most common causes of death in Germany and also worldwide and they are characterized by severe disease affliction. Currently, there are little effective opportunities for the therapy of most of the chronic lung diseases. For long-lasting and more successful treatment of lung diseases, a scientific and structural coordinated research is required rising to those challenges.


DZL - German Centre for Lung Research

The German Centre for Lung Research (DZL) is a BMBF initiated network, with the aim to develop in common a successful treatment of lung diseases and new options of prevention and diagnostics. In focus of interest stands a close with the clinical praxis interlocked basic, disease-, and patient-oriented research. In a bidirectional process the results of basic research can be rapid transferred into clinical practice.

Within the DZL, the leading German university-based and non-university lung centers will be merged in a coherent unit, focusing on the major lung diseases.


  • Asthma and Allergy
  • Chronic Obstructiv Lung Disease (COPD)
  • Cystic Fibrosis
  • Pneumonia - Acute Lung Injury/ARDS
  • Diffuse Parenchymal Lung Disease
  • Pulmonary Hypertension
  • Endstage Lung Disease
  • Lung Cancer


With the establishment of DZL, the BMBF aimed for assembling the best university and non-university research institutions in the field of pneumology.


  • Borstel/ Lübeck / Kiel/ Großhansdorf

Airway Research Center North (ARCN)

          Research Centre Borstel, University Lübeck, Christian    

          Albrechts University Kiel, Centre for Pneumology and

          Thoracic Surgery Grosshansdorf


  • Gießen / Marburg / Bad Nauheim

Universities Giessen und Marburg Lung Center (UGMLC)

          Justus Liebig University Giessen, Philipps University Marburg,

          Max-Planck Institute for Heart and Lung Research Bad



  • Hannover

Biomedical Research in Endstage and Obstructive Lung Disease (BREATH)

          Hannover Medical School, Leibniz Universität Hannover, 

          Fraunhofer Institute of Toxicology and Experimental

          Medicine Hannover (ITEM).


  • Heidelberg

Translational Lung Research Center Heidelberg (TLRC-H)

          Heidelberg University Medical School, Ruprecht Karls

          University Heidelberg, Thoraxklinik Universitätsklinikum

          Heidelberg, German Cancer Research Centre (DKFZ),

          European MolecularBiology Laboratory (EMBL).


  • München

Comprehensive Pneumology Center Munich (CPC-M)

          Helmholtz Zentrum München (HMGU), Ludwig Maximilians

          University München, LMU University Hospital, Asklepios

          Hospital München-Gauting.