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Introduction to Transcriptomics

The objective of an RNA expression study is to identify the proportion of active genes in a given celltype, a certain tissue, or, under specific physiological conditions. Whenever such an analysis is performed by use of genome-wide DNA-microarrays, one sole experiment yields information about the activation status of all of the thousands of genes present within a single cell. The data generated provide an optimal basis for the illustration of cell-biological states and changes in state in the global context of all genes involved, improving our understanding of physiological or pathological processes.


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