MHH Logo


Brandes V, Schelle I, Brinkmann S, Schulz F, Schwarz J, Gerhard R, Genth H.

Protection from C. difficile Toxin B-catalysed Rac/Cdc42 glucosylation by tauroursodeioxycholic acid-induced Rac/Cdc42 phosphorylation.

Biol Chem 2012;1;393(1-2);77-84



Olling A, Seehase S, Minton NP, Tatge H, Schröter S, Kohlscheen S, Pich A, Just I, Gerhard R.

Release of TcdA and TcdB from Clostridium cdi 630 is not affected by functional inactivation of the tcdE gene.

Microb Pathog 2012;52(1);92-100



Hülsenbeck SC, Rohrbeck A, Handreck A, Hellmich G, Kiaei E, Roettinger I, Grothe C, Just I, Haastert-Tallini K.

C3 Peptide Promotes Axonal Regeneration and Functional Motor Recovery after Peripheral Nerve Injury

Neurotherapeutics 2012;9;185-198



Gu S, Rumpel S, Zhou J, Strotmeier J, Bigalke H, Perry K, Shoemaker CB, Rummel A, Jin R.

Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.

Science 2012;Feb24;335(6071);977-981

Abtract   Artikel


Strotmeier J, Willjes G, Binz T, Rummel A.

Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: Increased therapeutic dosage and immunogenicity.

FEBS Lett 2012;17;586(4);310-313



Wellhöner H, Weiss A, Schulz A, Adermann K, Braitbard O, Bar-Sinai A, Hochmann J.

Reversing ABCB1-mediated multi-drug resistance from within cells using translocating immune conjugates

Journal of Drug Targeting 2012;20(5);445-452



Rotsch J, Rohrbeck A, May M, Kolbe T, Hagemann S, Schelle I, Just I, Genth H, Huelsenbeck SC.

Inhibition of macrophage migration by C. botulinum exoenzym C3

Naumyn-Schmiedebergs's Arch Pharmacol 2012;385(9);883-90. May29 [Epub ahead of print]



Hammerschmidt A, Chatterji B, Zeiser J, Schröder A, Genieser HG, Pich A, Kaever V, Schwede F, Wolter S, Seifert R.

Binding of Regulatory Subunits of Cyclic AMP-Dependent Protein Kinase to Cyclic CMP Agarose.

PLoS One 2012;7(7);e39848



Schwarz J, Proff J, Hävemeier A, Ladwein M, Rottner K, Barlag B, Pich A, Tatge H, Just I, Gerhard R.

Serine-71 phosphorylation of rac1 modulates downstream signaling.

PLoS One 2012;7(9):e44358



Auer M, Schweigreiter R, Hausott B, Thongrong S, Höltje M, Just I, Bandtlow C, Klimaschewski L.

Rho-independent stimulation of axon outgrowth and activation of the ERK and Akt signaling pathways by C3 transferase in sensory neurons.

Front Cell Neurosci 2012;6;43



Debez A, Braun HP, Pich A, Taamalli W, Koyro HW, Abdelly C, Huchzermeyer B.

Proteomic and physiological responses of the halophyte Cakile maritima to moderate salinity at the germinative and vegetative stages.

J Proteomics 2012;75(18);5667-5694



Chiaradia E, Avellini L, Tartaglia M, Gaiti A, Just I, Scoppetta F, Czentnar Z, Pich A.

Proteomic evaluation of sheep serum proteins.

BMC Vet Res 2012;8;66



Boetzkes A, Felkel KW, Zeiser J, Jochim N, Just I, Pich A.

Secretome analysis of Clostridium difficile strains.

Arch Microbiol 2012;194(8);675-687



Strotmeier J, Willjes G, Binz T, Rummel A.

Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: increased therapeutic dosage and immunogenicity.

FEBS Lett 2012;586(4);310-313



Bigalke H, Frevert J.

Botulinum toxin A: dose and immune response.

Int J Rehabil Res 2012;35(2);93



Hefter H, Hartmann C, Kahlen U, Moll M, Bigalke H.

Prospective analysis of neutralising antibody titres in secondary non-responders under continuous treatment with a botulinumtoxin type A preparation free of complexing proteins--a single cohort 4-year follow-up study.

BMJ Open 2012;2(4):10.1136/bmjopen-2011-000646. Print 2012



Huelsenbeck J, May M, Schulz F, Schelle I, Ronkina N, Hohenegger M, Fritz G, Just I, Gerhard R, Genth H.

Cytoprotective effect of the small GTPase RhoB expressed upon treatment of fibroblasts with the Ras-glucosylating Clostridium sordellii lethal toxin.

FEBS Lett 2012;586(20);3665-3673



Katsch K, de Jong SJ, Albrecht JC, Steger J, Genth H, Posern G, Biesinger B.

Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip.

Cell Commun Signal 2012;10(1):5-811X-10-5



May M, Kolbe T, Wang T, Schmidt G, Genth H.

Increased Cell-Matrix Adhesion upon Constitutive Activation of Rho Proteins by Cytotoxic Necrotizing Factors from E. Coli and Y. Pseudotuberculosis.

J Signal Transduct 2012;2012;570183



Weigoldt M, Meens J, Bange FC, Pich A, Gerlach GF, Goethe R.

Metabolic adaptation of Mycobacterium avium subsp. paratuberculosis to the gut environment.

Microbiology 2013;159(Pt.2);380-391



Rohrbeck A, Kolbe T, Hagemann S, Genth H, Just I.

Distinct biological activities of C3 and ADP-ribosyltransferase-deficient C3-E174Q.

FEBS J 2012;279(15);2657-2671