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List of Publications

 

Publications of (post-)doctoral students funded by IRTG 1273

names of DFG-funded (post-)doctoral students are marked in bold;
asterisks indicate publications with authors from Swedish and German IRTG members

 

Reviewed publications

a) Scientific journals

 

Jeron, A.*, J. D. Boehme*, J. Volckmar, M. Gereke, T. Yevsa, R. Geffers, C. A. Guzmán, J. Schreiber, S. Stegemann-Koniszewski#, D. Bruder#. 2018. Respiratory Bordetella bronchiseptica carriage is associated with broad phenotypic alterations of peripheral CD4⁺CD25⁺ T cells and differentially affects immune responses to secondary non-infectious and infectious stimuli in mice. Int. J. Mol. Sci. 19(9). * and # authors contribted equally

 

Stüve, P.*, L. Minarrieta*, H. Erdmann, C. Arnold-Schrauf, M. Swallow, M. Guderian, F. Krull, A. Hölscher, P. Ghorbani, J. Behrends, W.R. Abraham, C. Hölscher, T.D. Sparwasser, L. Berod. 2018. De novo fatty acid synthesis during mycobacterial infection is a prerequisite for the function of highly proliferative T cells, but not for dendritic cells or macrophages. Front Immunol. 9:495. * both authors contributed equally

 

Vashist, N., S. Trittel, T. Ebensen, B.J. Chambers, C.A. Guzmán, P. Riese. 2018. Influenza-activated ILC1s contribute to antiviral immunity partially influenced by differential GITR expression. Front Immunol. 9:505.

 

Velasquez, L.N.*, P. Stüve*, M.V. Gentilini, M. Swallow, J. Bartel, N.Y. Lycke, D. Barkan, M. Martina, H.D. Lujan, H. Kalay, Y. van Kooyk, T.D. Sparwasser, L. Berod. 2018. Targeting Mycobacterium tuberculosis antigens to dendritic cells via the DC-specific-ICAM3-grabbing-nonintegrin receptor induces strong T-helper 1 immune responses. Front. Immunol. 9:471. *both authors contributed equally

 

Bhushal S, M. Wolfsmüller, T.A. Selvakumar, L. Kemper, D. Wirth, M.W. Hornef, H. Hauser, M. Köster. 2017. Cell polarization and epigenetic status shape the heterogeneous response to Type III interfereons in intestinal epithelial cells. Front. Immunol. 8:671.

 

Billig, S., M. Schneefeld, C. Huber, G.A. Grassl, W. Eisenreich, F.C. Bange. 2017. Lactate oxidation facilitates growth of Mycobacterium tuberculosis in human macrophages. Sci Rep.7(1):6484.

 

Borst, K., T. Frenz, J. Spanier, P.K. Tegtmeyer, C. Chhatbar, J. Skerra, L. Ghita, S. Namineni, S. Lienenklaus, M. Köster, M. Heikenwaelder, G. Sutter, U. Kalinke. 2017. Type I interferon receptor-signaling delays Kupffer cell replenishment during acute fulminant viral hepatitis. J. Hepatol. 2017 Dec 2. pii: S0168-8278(17)32473-X. doi: 10.1016/j.jhep.2017.11.029. [Epub ahead of print]

 

Hirche, C., T. Frenz, S.F. Haas, M. Döring, K. Borst, P.K. Tegtmeyer, I. Brizic, S. Jordan, K. Keyser, C. Chhatbar, E. Pronk, S. Lin, M. Messerle, S. Jonjic, C.S. Falk, A. Trumpp, M.A.G. Essers, U. Kalinke. 2017. Systemic virus infections differentially modulate cell cycle state and functionality of long-term hematopoietic stem cells in vivo. Cell Rep. 19(11):2345-2356.

 

Mariggiò, G., S. Koch, G. Zhang, M. Weidner-Glunde, J. Rückert, S. Kati, S. Santag, T.F. Schulz. 2017. Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency. PLoS Pathog. 13(4):e1006335.

 

Pezoldt J, F. Pisano, W. Heine, M. Pasztoi, M. Rosenheinrich, A. M. Nuss, M. C. Pils, I. Prinz, R. Förster, J. Huehn, P. Dersch. 2017. CCR7 deficiency modulates T cell response and increases susceptibility to Yersinia pseudotuberculosis infection. J. Infect. Dis. 216(6):752-760.

 

Pfaender, S., S. Walter, E. Grabski, D. Todt, J. Bruening, I. Romero-Brey, T. Gather, R.J. Brown, K. Hahn, C. Puff, V.M. Pfankuche, F. Hansmann, A. Postel, P. Becher, V. Thiel, U. Kalinke, B. Wagner, R. Bartenschlager, W. Baumgärtner, K. Feige, T. Pietschmann, J.M. Cavalleri, E. Steinmann. 2017. Immune protection against reinfection with nonprimate hepacivirus. Proc. Natl. Acad. Sci. U S A. 114(12):E2430-E2439.

 

Reichert, C., A. Campe, S. Walter, S. Pfaender, K. Welsch, I. Ruddat, H. Sieme, K. Feige, E. Steinmann, J.-M.V. Cavalleri. 2017. Frequent occurrence of nonprimate hepacivirus infections in thoroughbred breeding horses - a crosssectional study for the occurrence of infections and potential risk factors. Vet. Microbiol. 203:315-322.

 

Schirdewahn, T., J. Grabowski, S. Owusu Sekyere, B. Bremer, A. Wranke, S. Lunemann, V. Schlaphoff, J. Kirschner, S. Hardtke, M.P. Manns, M. Cornberg, H. Wedemeyer, P.V. Suneetha. 2017. The third signal cytokine interleukin 12 rather than immune checkpoint inhibitors contributes to the functional restoration of hepatitis D virus-specific T cells. J. Infect. Dis. 215(1):139-149.

 

 

Selvakumar, T.A., S. Bhushal, U. Kalinke, D. Wirth, H. Hauser, M. Köster, M.W. Hornef. 2017. Identification of a predominantly interferon-λ-induced transcriptional profile in murine intestinal epithelial cells. Front Immunol.8:1302.

 

Siddharta, A., S. Pfaender, N.J. Vielle, R. Dijkman, M. Friesland, B. Becker, J. Yang, M. Engelmann, D. Todt, M.P. Windisch, F.H. Brill, J. Steinmann, J. Steinmann, S. Becker, M.P. Alves, T. Pietschmann, M. Eickmann, V. Thiel, E. Steinmann. 2017. Virucidal activity of WHO-recommended formulations against enveloped viruses including Zika, Ebola and emerging Coronaviruses. J. Infect. Dis. 215(6):902-906.

 

Stein, S.C., E. Faber, S.H. Bats, T. Murillo, Y. Speidel, N. Coombs, C. Josenhans. 2017. Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis. PLoS Pathog. 13(7):e1006514.

 

Torow, N., M.W. Hornef. 2017. The neonatal window of opportunity: Setting the stage for life-long host-microbial interaction and immune homeostasis. J. Immunol. 198(2):557-563.

 

Torow, N., B.J. Marsland, M.W. Hornef, E.S. Gollwitzer. 2017. Neonatal mucosal immunology. Mucosal Immunol. 10(1):5-17. Review.

 

Weidner-Glunde, M., G. Mariggiò, T.F. Schulz. 2017. Kaposi's Sarcoma Herpesvirus latency-associated nuclear antigen (LANA): Replicating and shielding viral DNA during viral persistence. J Virol. 91(14).  Review.

 

Arbore, G., E.E. West, R. Spolski, A.A.B. Robertson, A. Klos, C. Rheinheimer, P. Dutow, T. Woodruff, Z.X. Yu, L.A. O'Neill, R.C. Coll, A. Sher, W.J. Leonard, J. Köhl, P. Monk, M.A. Cooper, M. Arno, B. Afzali, H.J. Lachmann, A.P. Cope, K.D. Mayer-Barber, C. Kemper. 2016. T helper 1 immunity requires complement-driven, NLRP3 inflammasome activity in CD4+ T cells. Science. 352(6292):aad1210.

 

Barrozo, R.M., L.M. Hansen, A. M. Lam, E.C. Skoog, M.E. Martin, L.P. Cai, Y. Lin, A. Latoscha, S. Suerbaum, D.R. Canfield, J.V. Solnick. 2016. CagY is an immune-sensitive regulator of the Helicobacter pylori Type IV Secretion System. Gastroenterology.151(6):1164-1175.e3.

 

Behrens, W., T. Schweinitzer, J.L. McMurry, P.C. Loewen, F.F. Buettner, S. Menz, C. Josenhans. 2016. Localisation and protein-protein interactions of the Helicobacter pylori taxis sensor TlpD and their connection to metabolic functions. Sci. Rep. 6:23582.

 

Bubendorfer, S., J. Krebes, I. Yang, E. Hage, T.F. Schulz, C. Bahlawane, X. Didelot, S. Suerbaum. 2016. Genome-wide analysis of chromosomal import patterns after natural transformation of Helicobacter pylori. Nat. Commun. 7:11995.

 

Gather, T., S. Walter, S. Pfaender, D. Todt, K. Feige, E. Steinmann, J.M. Cavalleri. 2016. Acute and chronic infections with nonprimate hepacivirus in young horses. Vet. Res. 47(1):97.

 

Gather, T., S. Walter, D. Todt, S. Pfaender, R.J. Brown, A. Postel, P. Becher, A. Moritz, F. Hansmann, W. Baumgaertner, K. Feige, E. Steinmann, J.V. Cavalleri. 2016. Vertical transmission of hepatitis C virus-like non-primate hepacivirus in horses. J. Gen. Virol. 97(10):2540-2551.

 

Ginzel, M., Y. Yu, C. Klemann, X. Feng, R. von Wasielewski, J.K. Park, M. W. Hornef, N. Torow, G. Vieten, B.M. Ure, J.F. Kuebler, M. Lacher. 2016. The viral dsRNA analogue poly (I:C) induces necrotizing enterocolitis in neonatal mice. Pediatr. Res. 79(4):596-602.

 

Gogol-Doering, A., I. Ammar, C. Miskey, S. Gupta, M. Bunse, W. Chen, W. Uckert, T.F. Schulz, Z. Izsvak, Z. Ivics. 2016. Genome-wide profiling reveals remarkable parallels between insertion site selection properties of MLV retrovirus and the piggyback transposon in primary human CD4+ T cells. Mol. Ther. 24(3):592-606.

 

Hengst, J., C.S. Falk, V. Schlaphoff, K. Deterding, M.P. Manns, M. Cornberg, H. Wedemeyer. 2016. Direct-acting antiviral-induced hepatitis C virus clearance does not completely restore the altered cytokine and chemokine milieu in patients with chronic hepatitis C. J. Infect. Dis. 214(12):1965-1974.

 

*Hengst, J., B. Strunz, K. Deterding, H.G. Ljunggren, E. Leeansyah, M.P. Manns, M. Cornberg, J.K. Sandberg, H. Wedemeyer, N.K. Björkström. 2016. Nonreversible MAIT cell-dysfunction in chronic hepatitis C virus infection despite successful interferon-free therapy. Eur. J. Immunol. 46(9):2204-10.

 

Lorenz, A., V. Pawar, S. Häussler, S. Weiss. 2016. Insights into host-pathogen interactions from state-of-the-art animal models of respiratory Pseudomonas aeruginosa infections. FEBS Lett. 590(21):3941-3959. Review.

 

Pfaender, S., E. Grabski, C.N. Detje, N. Riebesehl, S. Lienenklaus, E. Steinmann, U. Kalinke, T. Pietschmann. 2016. Hepatitis C virus stimulates murine CD8α-like dendritic cells to produce Type I Interferon in a TRIF-dependent manner. PLoS Pathog. 12(7):e1005736.

 

Postel, A., J.M. Cavalleri, S. Pfaender, S. Walter, E. Steinmann, N. Fischer, K. Feige, L. Haas, P. Becher. 2016. Frequent presence of hepaci and pegiviruses in commercial equine serum pools. Vet. Microbiol. 182:8-14.

 

Sakthivel, P., N. Sharma, P. Klahn, M. Gereke, D. Bruder. 2016. Abscisic acid: A phytohormone and mammalian cytokine as novel pharmacon with potential for future development into clinical applications. Curr. Med. Chem. 23(15):1549-70. Review.

 

Salimi, M., S. Subramaniam, T. Selvakumar, X. Wang, S. Zemenides, D. Johnson, G. Ogg. 2016. Enhanced isolation of lymphoid cells from human skin. Clin. Exp. Dermatol. 41(5):552-6.

 

Stöhr, S., R. Costa, L. Sandmann, S. Westhaus, S. Pfaender, Anggakusuma, E. Dazert, P. Meuleman, F.W. Vondran, M.P. Manns, E. Steinmann, T. von Hahn, S. Ciesek. 2016. Host cell mTORC1 is required for HCV RNA replication. Gut. 65(12):2017-2028.

 

Walter, S., A. Rasche, A. Moreira-Soto, S. Pfaender, M. Bletsa, V.M. Corman, A. Aguilar-Setien, F. García-Lacy, A. Hans, D. Todt, G. Schuler, A. Shnaiderman-Torban, A. Steinman, C. Roncoroni, V. Veneziano, N. Rusenova, N. Sandev, A. Rusenov, D. Zapryanova, I. García-Bocanegra, J. Jores, A. Carluccio, M.C. Veronesi, J.M. Cavalleri, C. Drosten, P. Lemey, E. Steinmann, J.F. Drexler. 2016. Differential infection patterns and recent evolutionary origins of equine hepaciviruses in donkeys. J. Virol. 91(1).

 

Anggakusuma, A. Frentzen, E. Guerlevik, Q. Yuan, E. Steinmann, M. Ott, P. Staeheli, V. Hornung, F. Kuehnel, T. Pietschmann. 2015. Control of HCV replication in mouse liver derived cells by MAVS-dependent production of type-I and -III interferons. J. Virol. 89(7):3833-45.

 

Blanka,  A., J. Düvel, A. Dötsch, B. Klinkert, W. R. Abraham, V. Kaever, C. Ritter, F. Narberhaus, S. Häussler. 2015. Constitutive production of c-di-GMP is associated with mutations in a variant of Pseudomonas aeruginosa with altered membrane composition. Sci. Signal. 8(372):ra36.

 

Boianelli, A., V.K. Nguyen, T. Ebensen, K. Schulze, E. Wilk, N. Sharma, S. Stegemann-Koniszewski, D. Bruder, F.R. Toapanta, C.A. Guzmán, M. Meyer-Hermann, E.A. Hernandez-Vargas. 2015. Modeling influenza virus infection: A roadmap for influenza research. Viruses. 7(10):5274-304.  Review.

 

Walter, S., A. Bollenbach, J. Doerrbecker, S. Pfaender, R.J. Brown, G. Vieyres, C. Scott, R. Foster, A. Kumar, N. Zitzmann, S. Griffin, F. Penin, T. Pietschmann, E. Steinmann. 2016. Ion channel function and cross-species determinants in viral assembly of nonprimate Hepacivirus p7. J. Virol. 90(10):5075-89.

 

Bothe, M., P. Dutow, A. Pich, H. Genth,  A. Klos. 2015. DXD motif-dependent and -independent effects of the Chlamydia trachomatis cytotoxin CT166. Toxins 7(2):621-637.

 

Casilag, F., A. Lorenz, J. Krueger, F. Klawonn, S. Weiss, S. Häussler. 2015. The LasB elastase of Pseudomonas aeruginosa acts in concert with alkaline protease AprA to prevent flagellin-mediated immune recognition. Infect. Immun. 84(1):162-71.

 

*Dudek, M., F. Puttur, C. Arnold-Schrauf, A.A.. Kühl, B. Holzmann, B. Henriques-Normark, L. Berod, T. Sparwasser. 2015. Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection. Mucosal Immunol. 9(5):1288-302.

 

Dutow, P., L. Wask, M. Bothe, B. Fehlhaber, R. Laudeley, C. Rheinheimer , Z. Yang, G. Zhong, S. Glage, A. Klos. 2015. An optimized, fast-to-perform mouse lung infection model with the human pathogen Chlamydia trachomatis for in vivo screening of antibiotics, vaccine candidates and modified host-pathogen interactions. Pathog. Dis. 74(2).

 

*Hedenstierna, M., O. Weiland, A. Brass, D. Bankwitz, P. Behrendt, I. Uhnoo, S. Aleman, K. Cardell, A. Fryden, G. Norkrans, A. Eilard, H. Glaumann, T. Pietschmann, M. Sallberg, E. D. Brenndorfer. 2015. Long-term follow-up of successful hepatitis C virus therapy: waning immune responses and disappearance of liver disease are consistent with cure. Alimentary Pharmacology Ther. 41(6):532-543.

 

*Hengst, J., J. Theorell, K. Deterding, A. Potthoff, A. Dettmer, H. G. Ljunggren, H. Wedemeyer, N.K. Björkström. 2015. High-resolution determination of human immune cell signatures from fine-needle liver aspirates. Eur. J. Immunol. 45(7):2154-7.

 

Holzki, J.K., F. Dağ, I. Dekhtiarenko, U. Rand, R. Casalegno-Garduño, S. Trittel, T. May, P. Riese, L. Čičin-Šain. 2015. Type I IFN released by myeloid dendritic cells reversibly impairs Cytomegalovirus replication by inhibiting immediate early gene expression. J. Virol.  89(19):9886-95.

 

Janik, K., J. Bode, P. Dutow, R. Laudeley, R. Geffers, K. Sommer, S. Glage, A. Klos. 2015. Temperature and host cell-dependent changes in virulence of Chlamydia pneumoniae CWL029 in an optimized mouse infection model. Pathog. Dis. 73(1):1-8.

 

Lindner, C.*, I. Thomsen*, B. Wahl, M. Ugur, M. K. Sethi, M. Friedrichsen, A. Smoczek, S. Ott, U. Baumann, S. Suerbaum, S. Schreiber, A. Bleich, V. Gaboriau-Routhiau, N. Cerf-Bensussan, H. Hazanov, R. Mehr, P. Boysen, P. Rosenstiel, O. Pabst. 2015. Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota. Nat. Immunol. 16(8):880-888. *both authors contributed equally to this work

 

*Marquardt, N., V. Béziat, S. Nyström, J. Hengst, M.A. Ivarsson, E. Kekäläinen, H. Johansson, J. Mjösberg, M. Westgren, T.O. Lankisch, H. Wedemeyer, E.C. Ellis, H.G. Ljunggren, J. Michaëlsson, N.K. Björkström. 2015. Cutting Edge: Identification and characterization of human intrahepatic CD49a+ NK cells. J. Immunol. 194(6):2467-71.

 

Nitzsche, R., M. Rosenheinrich, B. Kreikemeyer, S. Oehmcke-Hecht. 2015. Streptococcus pyogenes triggers activation of the human contact system by streptokinase. Infect. Immun. 83(8):3035-42.

 

Owusu Sekyere, S., P.V. Suneetha, S. Hardtke, C.S. Falk, J. Hengst, M.P. Manns, M. Cornberg, H. Wedemeyer, V. Schlaphoff. 2015. Type I interferon elevates co-regulatory receptor expression on CMV- and EBV-specific CD8 T cells in chronic Hepatitis C. Front. Immunol. 6:270.

 

Pfaender, S., J.M. Cavalleri, S. Walter, J. Doerrbecker, B. Campana, R.J. Brown, P.D. Burbelo, A. Postel, K. Hahn, Anggakusuma, N. Riebesehl, W. Baumgärtner, P. Becher, M.H. Heim, T. Pietschmann, K. Feige, E. Steinmann. 2015. Clinical course of infection and viral tissue tropism of hepatitis C virus-like nonprimate hepaciviruses in horses. Hepatology. 61(2):448-59.

 

Pfaender, S., S. Walter, D. Todt, P. Behrendt, J. Doerrbecker, B. Woelk, M. Engelmann, U. Gravemann, A. Seltsam, J. Steinmann, P.D. Burbelo, F. Klawonn, K. Feige, T. Pietschmann, J.M. Cavalleri, E. Steinmann. 2015. Assessment of cross-species transmission of hepatitis C-related non-primate hepacivirus in a population of humans at high risk of exposure. J. Gen. Virol. 96(9):2632-42.

 

Riese, P.*, S. Trittel*, T. May, L. Cicin-Sain, B. J. Chambers, C. A. Guzmán. 2015. Activated NKT cells imprint NK-cell differentiation, functionality and education. Eur. J. Immunol. 45(6):1794-807. *both authors contributed equally to this work

 

Riese, P., S. Trittel, K. Schulze, C.A. Guzmán CA. 2015. Rodents as pre-clinical models for predicting vaccine performance in humans. Expert Rev. Vaccines. 14(9):1213-25. Review.

 

Rogalska-Taranta, M., A. A. Markova, A. Taranta, S. Lunemann, V. Schlaphoff, R. Flisiak, M. P. Manns, M. Cornberg, A.R. Kraft, H. Wedemeyer. 2015. Altered effector functions of NK cells in chronic hepatitis C are associated with IFNL3 polymorphism. J. Leukoc. Biol.  98(2):283-94.

 

Rosenheinrich, M., W. Heine, C.M. Schmühl, F. Pisano, P. Dersch. 2015. Natural killer cells mediate protection against Yersinia pseudotuberculosis in the mesenteric lymph nodes. PLoS One. 10(8):e0136290.

 

Rücker, N.*, S. Billig*, R. Bücker, D. Jahn, C. Wittmann, F.C. Bange. 2015. Acetate dissimilation and assimilation in Mycobacterium tuberculosis depend on carbon availability. J. Bacteriol. 197(19):3182-90. *both authors contributed equally to the work

 

Stern, C., N. Kasnitz, D. Kocijancic, S. Trittel, P. Riese, C. A. Guzmán, S. Leschner, S. Weiss. 2015. Induction of CD4+ and CD8+ anti-tumor effector T cell responses by bacteria mediated tumor therapy. Int. J. Cancer. 137(8):2019-28.

 

Thiel, N., J. Zischke, E. Elbasani, P. Kay-Fedorov, M. Messerle. 2015. Viral Interference with functions of the cellular receptor tyrosine phosphatase CD45. Viruses. 7(3):1540-1557.

 

Torow, N., O. Dittrich-Breiholz, M. Hornef. 2015. Transcriptional profiling of intestinal CD4+ T cells in the neonatal and adult mice. Genom.  Data 5:371-4.

 

Torow, N., K. Yu, K. Hassani, J. Freitag, O. Schulz, M. Basic, A. Brennecke, T. Sparwasser, N. Wagner, A. Bleich, M. Lochner, S. Weiss, R. Förster, O. Pabst, M.W. Hornef. 2015. Active suppression of intestinal CD4(+)TCRαβ(+) T-lymphocyte maturation during the postnatal period. Nat. Commun. 6:7725.

 

Vogt, C., C. Hackmann, A. Rabner, L. Koste, S. Santag, S. Kati, Y. Mandel-Gutfreund, T.F. Schulz, J. Bohne. 2015. ORF57 overcomes the detrimental sequence bias of Kaposi’s sarcoma-associated herpesvirus lytic genes. J. Virol. 89(9):5097-109.

 

Walker, A., K. Skibbe, E. Steinmann, S. Pfaender, T. Kuntzen, D.A. Megger, S. Groten, B. Sitek, G.M. Lauer, A.Y. Kim, T. Pietschmann, T.M. Allen, J. Timm. 2015. Distinct escape pathway by hepatitis C virus genotype 1a from a dominant CD8+ T cell response by selection of altered epitope processing. J. Virol. 90(1):33-42.

 

Arnold-Schrauf, C., M. Dudek, A. Dielmann, L. Pace, M. Swallow, F. Kruse, A.A. Kühl, B. Holzmann, L. Berod, T. Sparwasser. 2014. Dendritic cells coordinate innate immunity via MyD88 signaling to control Listeria monocytogenes infection. Cell Rep. 6(4)-698-708. 

 

Bankwitz, D., G. Vieyres, K. Hueging, J. Bitzegeio, M. Doepke, P. Chhatwal, S. Haid, M. T. Catanese, M. B. Zeisel, A. Nicosia, T. F. Baumert, L. Kaderali, T. Pietschmann. 2014. Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins. J. Virol.  88:12644-12655.

 

*Berglin, L., A. Bergquist, H. Johansson, H. Glaumann, C. Jorns, S. Lunemann, H. Wedemeyer, E.C. Ellis, N.K. Björkström. 2014. In situ characterization of intrahepatic non-parenchymal cells in PSC reveals phenotypic patterns associated with disease severity. PLoS One. 9(8):e105375.

 

Berod, L., P. Stüve, M. Swallow, C. Arnold-Schrauf, F. Kruse, M.V. Gentilini, J. Freitag, B. Holzmann, T. Sparwasser. 2014. MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection. Eur. J. Immunol. 44(5):1399-409.

 

Berod, L.*, P. Stüve*, F. Varela, J. Behrends, M: Swallow, F. Kruse, F. Krull, P. Ghorbani, C.T. Mayer, C. Hölscher, T. Sparwasser. 2014. Rapid rebound of the Treg compartment in DEREG mice limits the impact of Treg depletion on mycobacterial burden, but prevents autoimmunity. PLoS One. 9(7):e102804. *both authors contributed equally

 

Elbasani, E., I. Gabaev, L. Steinbrück, M. Messerle, E.M. Borst. 2014. Analysis of essential viral gene functions after highly efficient adenofection of cells with cloned human cytomegalovirus genomes. Viruses. 6(1):354-70.

 

*Fang, X., I. Ahmad, A. Blanka, M. Schottkowski, A. Cimdins, M.Y. Galperin, U. Römling, M. Gomelsky. 2014. GIL, a new c-di-GMP-binding protein domain involved in regulation of cellulose synthesis in enterobacteria. Mol. Microbiol. 93(3):439-52.

 

Gabaev, I.*, E. Elbasani*, S. Ameres, L. Steinbrück, R. Stanton, M. Döring, T. Lenac Rovis, U. Kalinke, S. Jonjic, A. Moosmann, M. Messerle. 2014. Expression of the hman cytomegalovirus UL11 glycoprotein in viral infection and evaluation of its effect on virus-specific CD8 T cells. J. Virol. 88(24):14326-39. *contributed equally to the manuscript

 

Grabski, E., I. Wappler, S. Pfaender, E. Steinmann, S. Haid, A. Dzionek, T. Pietschmann, U. Kalinke. 2014.  Efficient virus assembly, but not infectivity, determines the magnitude of hepatitis C virus induced interferon-α responses of plasmacytoid dendritic cells. J. Virol.  89(6):3200-8.

 

Günther, C., B. Buchen, G.W. He, M. Hornef, N. Torow, H. Neumann, N. Wittkopf, E. Martini, M. Basic, A. Bleich, A. J. Watson, M.F. Neurath, C. Becker. 2014. Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways. Gut. 64(4):601-10.

 

Gutowska-Owsiak, D., M. Salimi, T.A. Selvakumar, X. Wang, S. Taylor, G.S. Ogg. 2014. Histamine exerts multiple effects on expression of genes associated with epidermal barrier function. J. Investig. Allergol. Clin. Immunol. 24(4):231-9.

 

Hueging, K., M. Doepke, G. Vieyres, D. Bankwitz, A. Frentzen, J. Doerrbecker, F. Gumz, S. Haid, B. Wölk, L. Kaderali, T. Pietschmann. 2014. Apolipoprotein E co-determines tissue-tropism of hepatitis C virus and it is crucial for viral cell-to cell transmission by contributing to a post-envelopment step of assembly. J. Virol. 88:1433-1446.

 

*Kiene, M., B. Rethi, M. Jansson, S. Dillon, E. Lee, R. Lantto, C. Wilson, S. Pöhlmann, F. Chiodi. 2014. Toll-like receptor 3 signalling up-regulates expression of the HIV co-receptor G-protein coupled receptor 15 on human CD4+ T cells. PLoS One. 9(2):e88195.

 

Knittler, M. R., A. Berndt, S. Böcker, P. Dutow, F. Hänel, D. Heuer, D. Kägebein, A. Klos, S. Koch, E. Liebler-Tenorio, C. Ostermann, P. Reinhold, H. P. Saluz, G. Schöfl, P. Sehnert, K. Sachse K. 2014. Chlamydia psittaci: New insights into genomic diversity, clinical pathology, host-pathogen interaction and anti-bacterial immunity. Int. J. Med. Microbiol. 304(7):877-93.

 

Krebes, J., X. Didelot, L. Kennemann, S. Suerbaum. 2014. Bidirectional genomic exchange between Helicobacter pylori strains from a family in Coventry, United Kingdom. Int. J. Med. Microbiol. 304(8):1135-46.

 

*Lim, C.H., S. Voedisch, B. Wahl, S. F. Rouf, R. Geffers, M. Rhen, O. Pabst. 2014. Independent bottlenecks characterize colonization of systemic compartments and gut lymphoid tissue by salmonella. PLoS Pathog. 10(7):e1004270.

 

Lunemann, S., J. Grabowski, H. Wedemeyer. 2014.  Immunopathogenesis of Hepatitis D. In: Liver Immunology: Principles and Practice. M.E Gershwin, J.M. Vierling, M.P. Manns (Eds.), Springer Science+Business Media, New York, pp. 231-241.

 

*Lunemann, S., D. F. Malone, J. Grabowski, K. Port, V. Béziat, B. Bremer, K.J. Malmberg, M.P. Manns, J.K. Sandberg, M. Cornberg, H.G. Ljunggren, H. Wedemeyer, N.K. Björkström. 2014. Effects of HDV infection and pegylated interferon α treatment on the natural killer cell compartment in chronically infected individuals. Gut. 64(3):469-82.

 

Markova,  A.A., U. Mihm, V. Schlaphoff, S. Lunemann, N. Filmann, B. Bremer, T. Berg, C. Sarrazin, S. Zeuzem, M.P. Manns, M. Cornberg, E. Herrmann, H. Wedemeyer. 2014. PEG-IFN alpha but not Ribavirin alters NK cell phenotype and function in patients with chronic Hepatitis C. PLoS One. 9(4):e94512.

 

Mayer,  C.T.*, P. Ghorbani*, A.A. Kühl, P. Stüve, M. Hegemann, L. Berod, M.E. Gershwin, T. Sparwasser. 2014. Few Foxp3+ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity. Eur. J. Immunol. 44(10):2990-3002. *both authors contributed equally

 

Mayer, C.T.*, P. Ghorbani*, A. Nandan, M. Dudek, C. Arnold-Schrauf, C. Hesse, L. Berod, P. Stüve, F. Puttur, M. Merad, T. Sparwasser. 2014. Selective and efficient generation of functional Batf3-dependent CD103+ dendritic cells from mouse bone marrow. Blood.  124(20):3081-91. *both authors contributed equally

 

Nell, S., L. Kennemann, S. Schwarz, C. Josenhans, S. Suerbaum. 2014. Dynamics of Lewis b binding and sequence variation of the babA adhesin gene during chronic Helicobacter pylori infection in humans. MBio. 5(6). pii: e02281-14. 

 

Pfaender, S., J. Brinkmann, D. Todt, N. Riebesehl, J. Steinmann, J. Steinmann, T. Pietschmann, E. Steinmann. 2014. Mechanisms of methods for hepatitis c virus  inactivation. Appl. Environ. Microbiol. 81(5):1616-21.

 

Pfaender, S., R.J. Brown, T. Pietschmann, E. Steinmann. 2014. Natural reservoirs for homologs of hepatitis C virus. Emerg. Microbes Infect. 3(3):e21.

 

Pisano, F., W. Heine, M. Rosenheinrich, J. Schweer, A.M. Nuss, P. Dersch. 2014. Influence of PhoP and intra-species variations on virulence of Yersinia pseudotuberculosis during the natural oral infection route. PLoS One. 9(7):e103541.

 

Pustelny C., U. Komor, V. Pawar, A. Lorenz, A. Bielecka, A. Moter, B. Gocht, D. Eckweiler, C. Grothe, H. Lünsdorf, S. Weiss, S. Häussler. shared last authorship. 2014. Contribution of Veillonella parvula to Pseudomonas aeruginosa mediated pathogenicity in a murine tumor model system. Infect. Immun. 83(1):417-29.

 

Riese, P., P. Sakthivel, S. Trittel, C.A. Guzmán. 2014. Intranasal formulations: promising strategy to deliver vaccines. Expert Opin. Drug Deliv.  11(10):1619-34.

 

Seitz, M., A. Beineke, A. Singpiel, J. Willenborg, P. Dutow, R. Goethe, P. Valentin-Weigand, A. Klos, C. G. Baums. 2014. Role of capsule and suilysin in mucosal infection of complement-deficient mice with Streptococcus suis. Infect. Immun. 82(6):2460-71.

 

Spanier, J., S. Lienenklaus, J. Paijo, A. Kessler, K. Borst, S. Heindorf, D.P. Baker, A. Kröger, S. Weiss, C.N. Detje, P. Staeheli, U. Kalinke. 2014. Concomitant TLR/RLH signaling of radioresistant and radiosensitive cells is essential for protection against vesicular stomatitis virus infection. J. Immunol.  193(6):3045-54. 

 

Stockinger, S., T. Albers, C.U. Duerr, S. Ménard, K. Pütsep, M. Andersson, M.W. Hornef. 2014. Interleukin-13-mediated paneth cell degranulation and antimicrobial peptide release. J. Innate Immun. 6(4):530-41.

 

Stockinger, S., C. U. Duerr, M. Fulde, T. Dolowschiak, J. Pott, I. Yang, D. Eibach, F. Bäckhed, S. Akira, S. Suerbaum, M. Brugman, M.W. Hornef. 2014. TRIF signaling drives homeostatic intestinal epithelial antimicrobial peptide expression. J. Immunol.  193(8):4223-34.

 

Vercauteren, K., N. Van Den Eede, A. A. Mesalam, S. Belouzard, M. T. Catanese, D. Bankwitz, F. Wong-Staal, R. Cortese, J. Dubuisson, C. M. Rice, T. Pietschmann, G. Leroux-Roels, A. Nicosia, P. Meuleman. 2014. Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents. Hepatology 60:1508-1518.

 

Yang, Z., T. Conrad, Z. Zhou, J. Chen, P. Dutow, A. Klos, G. Zhong. 2014. Complement factor C5 but not C3 contributes significantly to hydrosalpinx development in mice infected with Chlamydia muridarum. Infect. Immun. 82(8):3154-63.

 

Zhang, K., A. Dupont, N. Torow, F. Gohde, S. Leschner, S. Lienenklaus, S. Weiss, M. M. Brinkmann, M. Kühnel, M. Hensel, M. Fulde, M. W. Hornef. 2014. Age-dependent enterocyte invasion and microcolony formation by salmonella. PLoS Pathog. 2014;10(9):e1004385.

 

*Ahmad, I., E. Wigren, S. Le Guyon, S. Vekkeli, A. Blanka, Y. el Mouali, N. Anwar, M.L. Chuah, H. Lünsdorf, R. Frank, M. Rhen, Z. X. Liang, Y. Lindqvist, U. Römling. 2013. The EAL-like protein STM1697 regulates virulence phenotypes, motility and biofilm formation in Salmonella typhimurium. Mol. Microbiol. 90(6):1216-32.

 

Anggakusuma, C.C. Colpitts, L.M. Schang, H. Rachmawati, A. Frentzen, S. Pfaender, P. Behrendt, R.J. Brown, D. Bankwitz, J. Steinmann, M. Ott, P. Meuleman, C.M. Rice, A. Ploss, T. Pietschmann, E. Steinmann. 2013. Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut. 63(7):1137-49.

 

Behrens, W., T. Schweinitzer, J. Bal, M. Dorsch, A. Bleich, F. Kops, B. Brenneke, X. Didelot, S. Suerbaum, C. Josenhans. 2013. Role of energy sensor TlpD of Helicobacter pylori in gerbil colonization and genome analyses after adaptation in the gerbil. Infect. Immun. 81(10):3534-51.

 

Blanka, A.*, S. Schulz*, D. Eckweiler, R. Franke, A. Bielecka, T. Nicolai, F. Casilag, J. Düvel, W. R. Abraham, V. Kaever, S. Häussler. 2013. Identification of the alternative sigma factor SigX regulon and its implications for Pseudomonas aeruginosa pathogenicity. J. Bacteriol. 196(2):345-56. * both authors contributed equally to this work

 

*Denkel, L. A., M. Rhen, F. C. Bange. 2013. Biotin sulfoxide reductase contributes to oxidative stress tolerance and virulence in Salmonella enterica serovar Typhimurium. Microbiology. 159(Pt 7):1447-1458.

 

Doerrbecker, J., P. Meuleman, J. Kang, N. Riebesehl, C. Wilhelm, M. Friesland, S. Pfaender, J. Steinmann, T. Pietschmann, E. Steinmann. 2013. Thermostability of seven hepatitis C virus genotypes in vitro and in vivo. J. Viral. Hepat. 20(7):478-85.

 

Dutow, P., B. Fehlhaber, J. Bode, R. Laudeley, C. Rheinheimer, S. Glage, R. A. Wetsel, O. Pabst, A. Klos. 2013. The complement C3a receptor is critical in defense against Chlamydia psittaci in mouse lung infection and required for antibody and optimal T cell response. J. Infect. Dis. 209(8):1269-78. 

 

Dutow, P., S. Lingner, R. Laudeley, S. Glage, H.G. Hoymann, A.M. Dittrich, B. Fehlhaber, M. Müller, A. Braun, A. Klos. 2013. Severity of allergic airway disease to house dust mite allergen is not increased after clinical recovery of lung infection with Chlamydia pneumoniae in mice. Infect. Immun. 81(9):3366-74.

 

Frentzen, A., Angakusuma, E. Guerlevik, K. Hueging, S. Knocke, C. Ginkel, R. J. Brown, M. Heim, M. T. Dill, A. Kröger, U. Kalinke, L. Kaderali, F. Kuehnel, T. Pietschmann. 2013. Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells. Hepatology. 59(1):78-88.

 

Gentzsch, J., C. Brohm, E. Steinmann, M. Friesland, N. Menzel, G. Vieyres, P.M. Perin, A. Frentzen, L. Kaderali, T. Pietschmann. 2013. Hepatitis c Virus p7 is critical for capsid assembly and envelopment. PLoS Pathog. 9(5): e1003355.

 

Gupta, S.S., T. Maetzig, G. N. Maertens, A. Sharif, M. Rothe, M. Weidner-Glunde, M. Galla, A. Schambach, P. Cherepanov, T. F. Schulz. 2013. Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration. J. Virol. 87(23):12721-36.

 

Haas, D.A., K. Bala, G. Büsche, M. Weidner-Glunde, S. Santag, S. Kati, S. Gramolelli, M. Damas, O. Dittrich-Breiholz, M. Kracht, J. Rückert, Z. Varga, G. Keri, T.F. Schulz. 2013. The inflammatory kinase MAP4K4 promotes reactivation promotes reactivation of Kaposi’s Sarcoma Herpesvirus and enhances the invasiveness of infected endothelial cells. PLoS Pathog. 9(11):e1003737.

 

Krebes, J., R. D. Morgan, B. Bunk, C. Spröer, K. Luong, R. Parusel, B. P. Anton, C. König, C. Josenhans, J: Overmann, R. J. Roberts, J. Korlach, S. Suerbaum. 2013. The complex methylome of the human gastric pathogen Helicobacter pylori. Nucleic Acids Res. 42(4):2415-32. 

 

*Lunemann, S., D.F. Malone, J. Hengst, K. Port, J. Grabowski, K. Deterding, A. Markova, B. Bremer, V. Schlaphoff, M. Cornberg, M.P. Manns, J.K. Sandberg, H.G. Ljunggren, N.K. Björkström, H. Wedemeyer. 2013. Compromised function of natural killer cells in acute and chronic viral hepatitis. J. Infect. Dis. 209(9):1362-73.

 

Pfaender, S., J. Heyden, M. Friesland, S. Ciesek, A. Ejaz, J. Steinmann, J. Steinmann, A. Malarski, H. Stoiber, G. Tsiavaliaris, W. Bader, G. Jahreis, T. Pietschmann, E. Steinmann. 2013. Inactivation of hepatitis C virus infectivity by human breast milk. J. Infect. Dis. 208(12):1943-52.

 

Rüger, K., A. Hampel, S. Billig, N. Rücker, S. Suerbaum, F. C. Bange. 2013. Characterization of rough and smooth morphotypes of Mycobacterium abscessus isolated from clinical specimens. J. Clin. Microbiol. 52(1):244-50.

 

Solomon Tsegaye, T., K. Gnirß, N. Rahe-Meyer, M. Kiene, A. Kühl, G. Behrens, J. Münch, S. Pöhlmann. 2013. Platelet activation suppresses HIV-1 spread in adjacent T cells. Retrovirology. 10(1):48.

 

Scheiter, M., B. Bulitta, M. van Ham, F. Klawonn, S. König, L. Jänsch. 2013. Protein kinase inhibitors CK59 and CID755673 alter primary human NK cell effector functions. Front. Immunol. 4:66. 

 

Scheiter, M., U. Lau, M. van Ham, B. Bulitta, L. Groebe, H. Garritsen, F. Klawonn, S. Koenig, L. Jaensch. 2013. Proteome analysis of distinct developmental stages of human natural killer cells. Mol. Cell. Proteomics. 12(5):1099-114. 

 

*Stegemann-Koniszewski, S., M. Gereke, S. Orrskog, S. Lienenklaus, B. Pasche, S.R. Bader, A.D. Gruber, S. Akira, S. Weiss, B. Henriques-Normark, D. Bruder, M. Gunzer. 2013. TLR7 contributes to the rapid progression but not to the overall fatal outcome of secondary pneumococcal disease following influenza A virus infection. J. Innate Immun. 5(1):84-96.

 

Steinmann, E., J. Doerrbecker, M. Friesland, N. Riebesehl, C. Ginkel, J. Hillung, J. Gentzsch, C. Lauber, R. Brown, A. Frentzen, T. Pietschmann. 2013. Characterization of hepatitis C virus intra- and inter-genotypic chimeras reveals a role of the glycoproteins in virus envelopment. J. Virol. 87:13297-13306.

 

Westhaus, S., D. Bankwitz, S. Ernst, K. Rohrmann, I. Wappler, C. Agne, M. Luchtefeld, B. Schieffer, C. Sarrazin, M. P. Manns, T. Pietschmann, S. Ciesek, T. von Hahn. 2013. Characterization of the inhibition of hepatitis C virus entry by in vitro-generated and patient-derived oxidized low-density lipoprotein. Hepatology 57:1716-1724.

 

Behrens, W., T. Bönig, S. Suerbaum, C. Josenhans. 2012. Genome sequence of Helicobacter pylori hpEurope Strain N6. J. Bacteriol. 194(14):3725-6.

 

Bode, J., P. Dutow, K. Sommer, K. Janik, S. Glage, B. Tümmler, A. Munder, R. Laudeley, K. Sachse, A. Klos. 2012. A new role of the complement system, C3 provides protection in a mouse model of lung infection with intracellular Chlamydia psittaci. PLoS One. 7(11):e50327.

 

Chhatwal, P., D. Bankwitz, J. Gentzsch, A. Frentzen, P. Schult, V. Lohmann, T. Pietschmann. 2012. Bile acids specifically increase hepatitis C virus RNA-replication. PLoS One. 7(4):e36029.

 

Duerr, C.U., M. W. Hornef. 2012. The mammalian intestinal epithelium as integral player in the establishment and maintenance of host-microbial homeostasis. Semin. Immunol. 24(1):25-35.

 

Frentzen, A., K. Hueging, J. Bitzegeio, T. Pietschmann, E. Steinmann. 2012. Two methods of heterokaryon formation to discover HCV restriction factors. J. Vis. Exp. (65):e4029.

 

Haid, S., A. Novodomska, J. Gentzsch, C. Grethe, S. Geuenich, D. Bankwitz, P. Chhatwal, B. Jannack, T. Hennebelle, F. Bailleul, O. T. Keppler, M. Poenisch, R. Bartenschlager, C. Hernandez, M. Lemasson, A. R. Rosenberg, F. Wong-Staal, E. Davioud-Charvet, T. Pietschmann. 2012. A plant-derived flavonoid inhibits entry of all HCV genotypes into human hepatocytes. Gastroenterology. 143:213-222 e215.

 

Jäger, W.*, S. Santag*, M. Weidner-Glunde, E. Gellermann, S. Kati, M. Pietrek, A. Viejo-Borbolla, T. F. Schulz. 2012. The ubiquitin-specific protease USP7 modulates the replication of Kaposi's Sarcoma Herpesvirus latent episomal DNA. J. Virol. 86(12):6745-57. *both authors contributed equally

 

Jeron, A., W. Hansen, F. Ewert, J. Buer, R. Geffers, D. Bruder. 2012. ChIP-on-chip analysis identifies IL-22 as direct target gene of ectopically expressed FOXP3 transcription factor in human T cells. BMC Genomics. 13:705.

 

Kennemann, L., B. Brenneke, S. Andres, L. Engstrand, T. F. Meyer, T. Aebischer, C. Josenhans, S. Suerbaum. 2012. In vivo sequence variation in HopZ, a phase variable outer membrane protein of Helicobacter pylori. Infect. Immun. 80(12):4364-73.

 

*Kiene, M., A. Marzi, A. Urbanczyk, S. Bertram, T. Fisch, I. Nehlmeier, K. Gnirß, C.B. Karsten, D. Palesch, J. Münch, F. Chiodi, S. Pöhlmann, I. Steffen. 2012. The role of the alternative coreceptor GPR15 in SIV tropism for human cells. Virology. 433(1):73-84. 

 

*König, S., M. Nimtz, M. Scheiter, H.G. Ljunggren, Y.T. Bryceson, L. Jänsch. 2012. Kinome analysis of receptor-induced phosphorylation in human natural killer cells. PLoS One. 7(1):e29672.

 

König, S., M. Probst-Kepper, T. Reinl, A. Jeron, J. Huehn, B. Schraven, L. Jänsch. 2012. First insight into the kinome of human regulatory T cells. PLoS One. 2012;7(7):e40896.

 

Lunemann, S., V. Schlaphoff, M. Cornberg, H. Wedemeyer. 2012. NK cells in hepatitis C: role in disease susceptibility and therapy. Dig. Dis. 30 Suppl 1:48-54.

 

Malone, J.G., T. Jaeger, P. Manfredi, A. Dötsch, A. Blanka, R. Bos, G. R. Cornelis, S. Häussler, U. Jenal. 2012. The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways. PLoS Pathog. 8(6): e1002760.

 

Menzel, N., W. Fischl, K. Hueging, D. Bankwitz, A. Frentzen, S. Haid, J. Gentzsch, L. Kaderali, R. Bartenschlager, T. Pietschmann. 2012. MAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious Hepatitis C virus particles. PLoS Pathog. 8(7):e1002829.

 

Moccia, C.*, J. Krebes*, S. Kulick*, X Didelot, C. Kraft, C. Bahlawane, S. Suerbaum. 2012. The nucleotide excision repair (NER) system of Helicobacter pylori: role in mutation prevention and chromosomal import patterns after natural transformation. BMC Microbiol. 12:67. * The authors contributed equally to the work.

 

Pott, J., S. Stockinger, N. Torow, A. Smoczek, C. Lindner, G. McInerney, F. Bäckhed, U. Baumann, O. Pabst, A. Bleich, M. W. Hornef. 2012. Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility. PLoS Pathog. 8(5):e1002670.

 

Quade, N.#, C. Mendonca#, K. Herbst, A. K. Heroven, C. Ritter, D. W. Heinz, P. Dersch. 2012. Structural basis for intrinsic thermosensing by the master virulence regulator RovA of Yersinia. J. Biol. Chem. 287(43):35796-803. #both authors contributed equally to this work

 

Ruhl, M., P. Chhatwal, H. Strathmann, T. Kuntzen, D. Bankwitz, K. Skibbe, A. Walker, F. M. Heinemann, P. A. Horn, T. M. Allen, D. Hoffmann, T. Pietschmann, J. Timm. 2012. Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope. J. Virol. 86:991-1000.

 

Santag, S., W. Jäger, C.B. Karsten, S. Kati, M. Pietrek, D. Steinemann, G. Sarek, P.M. Ojala, T.F. Schulz. 2012. Recruitment of the tumour suppressor protein p73 by Kaposi's Sarkoma Herpesvirus latent nuclear antigen contributes to the survival of primary effusion lymphoma cells. Oncogene. 32(32):3676-85.

 

Santag, S., T.F. Schulz. 2012. Rhadinoviruses: KSHV and associated malignancies. In: Cancer associated viruses. Robertson E.S. (Ed.), Springer Science + Business Media, New York, pp. 215-249.

 

*Stegmann, K. A., N. K. Björkström, S. Ciesek, S. Lunemann, J. Jaroszewicz, J. Wiegand, P. Malinski, L. B. Dustin, C. M. Rice, M. P. Manns, T. Pietschmann, M. Cornberg, HG. Ljunggren, H. Wedemeyer. 2012. Interferon α-stimulated natural killer cells from patients with acute Hepatitis C Virus (HCV) infection recognize HCV-infected and uninfected hepatoma cells via DNAX accessory molecule-1. J. Infect. Dis. 205(9):1351-62.

 

Taft, F., K. Harmrolfs, I. Nickeleit, A. Heutling, M. Kiene, N. Malek, F. Sasse, A. Kirschning. 2012. Combined muta- and semisynthesis: a powerful synthetic hybrid approach to access target specific antitumor agents based on ansamitocin P3. Chemistry.18(3):880-6.

 

von Hahn, T., C. Schiene-Fischer, N.D. Van, S. Pfaender, B. Karavul, E. Steinmann, A. Potthoff, C. Strassburg, N. Hamdi, A. I. Abdelaziz, C. Sarrazin, T. Müller, T. Berg, E. Trépo, H. Wedemeyer, M.P. Manns, T. Pietschmann, S. Ciesek. 2012. Hepatocytes that express variants of cyclophilin A are resistant to HCV infection and replication. Gastroenterology. 143(2):439-47.

 

Winkler, M., S. Bertram, K. Gnirß, I. Nehlmeier, A. Gawanbacht, F. Kirchhoff, C. Ehrhardt, S. Ludwig, M. Kiene, A.S. Moldenhauer, U. Goedecke, C.B. Karsten, A. Kühl, S. Pöhlmann. 2012. Influenza A virus does not encode a tetherin antagonist with Vpu-like activity and induces IFN-dependent expression in infected cells. PLoS One. 7(8):e43337.

 

Zaoui, C., J. Overhage, D. Löns, A. Zimmermann, M. Müsken, P. Bielecki, C. Pustelny, T. Becker, M. Nimtz, S. Häussler. 2012. An orphan sensor kinase controls quinolone signal production via MexT in Pseudomonas aeruginosa. Mol. Microbiol. 83(3):536-47.

 

Alkharsah, K.R., V.V. Singh, R. Bosco, S. Santag, A. Grundhoff, A. Konrad, M. Stürzl, D. Wirth, O. Dittrich-Breiholz, M. Kracht, T.F. Schulz. 2011. Deletion of Kaposi's sarcoma herpesvirus FLICE inhibitory protein (vFLIP) from the viral genome compromises the activation of STAT-1 responsive cellular genes and spindle cell formation in endothelial cells. J. Virol. 85(19):10375:88. 

 

*Denkel, L. A., S. A. Horst, S. F. Rouf, V. Kitowski, O. M. Böhm, M. Rhen, T. Jäger, F.-C. Bange. 2011. Methionine sulfoxide reductases are essential for virulence of Salmonella Typhimurium. PLoS. 6(11):e26974. 

 

Frentzen, A., K. Hüging, J. Bitzegeio, M. Friesland, S. Haid, J. Gentzsch, M. Hoffmann, D. Lindemann, G. Zimmer, F. Zielecki, F. Weber, E. Steinmann, T. Pietschmann. 2011. Completion of Hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines. PLoS Pathog. 7(4):e1002029.

 

Griffin, A. J., L. X. Li, S. Voedisch, O. Pabst, S. J. McSorley. 2011. Dissemination of persistent intestinal bacteria via the mesenteric lymph nodes causes typhoid relapse. Infect. Immun. 79(4):1479-88. 

Kennemann, L., X. Didelot, T. Aebischer, S. Kuhn, B. Drescher, M. Droege, R. Reinhardt, P. Correa, T. F. Meyer, C. Josenhans, D. Falush, S. Suerbaum. 2011. Helicobacter pylori genome evolution during human infection. Proc. Natl. Acad. Sci. U S A. 108(12):5033-8. 

 

Kühl, A., M. Hoffmann, M. A. Müller, V. J. Munster, K. Gnirss, M. Kiene, T.S. Tsegaye, G. Behrens, G. Herrler, H. Feldmann, C. Drosten, S. Pöhlmann. 2011. Comparative analysis of Ebola virus glycoprotein interactions with human and bat cells. J. Infect. Dis. 204 Suppl 3:S840-9.

 

Pott, J, T. Mahlakõiv, M. Mordstein, C. U. Duerr, T. Michiels, S. Stockinger, P. Staeheli, MW Hornef. 2011. IFN-λ determines the intestinal epithelial antiviral host defense. Proc. Natl. Acad. Sci. U S A. 108(19):7944-9.

 

Schlaphoff, V., S. Lunemann, P.V. Suneetha, J. Jaroszewicz, J. Grabowski, J. Dietz, F. Helfritz, H. Bektas, C. Sarrazin, M.P. Manns, M. Cornberg, H. Wedemeyer. 2011. Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells. PLoS Pathog. 7(5):e1002045.

 

TrehanPati, N., S. Sukriti, R. Geffers, S. Hissar, P. Riese, T. Toepfer, C.A. Guzman, S.K. Sarin. 2011. Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase. J. Clin. Immunol. 31(3):498-508.

 

Bankwitz, D., E. Steinmann, J. Bitzegeio, S. Ciesek, M. Friesland, E. Hermann, M. B. Zeisel, T. F. Baumert, Z. Keck, S. K. H. Foung, E. I. Pécheur, T. Pietschmann. 2010. Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site and protects conserved neutralizing epitopes. J. Virol. 84(11):5751-63.  

 

Bitzegeio, J., D. Bankwitz., K. Hueging, S. Haid, C. Brohm. M.B. Zeisel, E. Hermann, M. Iken, M. Ott, T.F. Baumert, T. Pietschmann. 2010. Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors. PLoS Pathog. 6(7):e1000978.

 

*Björkström, N.K., P. Riese, F. Heuts, S. Andersson, C. Fauriat, M. A. Ivarsson, A. T. Björklund, M. Flodström-Tullberg, J. Michaëlsson, M. E. Rottenberg, C. A. Guzmán, H.-G. Ljunggren, K.-J. Malmberg. 2010. Expression patterns of NKG2A, KIR and CD57 define a process of CD56dim NK cell differentiation uncoupled from NK cell education. Blood. 116(19):3853-64.

 

Bruns, S., O. Kniemeyer, M. Hasenberg, V. Aimanianda, S. Nietzsche, A. Thywissen, A. Jeron, J. P. Latgé, A. A. Brakhage, M. Gunzer. 2010. Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA. PLoS Pathog. 6(4):e1000873.

 

Chassin, C., M. Kocur, J. Pott, C. U. Duerr, D. Gütle, M. Lotz, M. W. Hornef. 2010. miR-146a mediates protective innate immune tolerance in the neonate intestine. Cell Host Microbe. 8(4):358-88.

 

*Coombs N., R. Sompallae, P. Olbermann, S. Gastaldello, D. Göppel, M.G. Masucci, C. Josenhans. 2010. Helicobacter pylori affects the cellular deubiquitinase USP7 and ubiquitin-regulated components TRAF6 and the tumour suppressor p53. Int. J. Med. Microbiol. 301(3):213-24. 

 

*Duerr, C. U., N. H. Salzman, A. Dupont, A. Szabo, B. H. Normark, S. Normark, R. M. Locksley, P. Mellroth, M. W. Hornef. 2010. Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes. Mucosal Immunol. 4(3):325-34.

 

*Horst, S. A., T. Jaeger, L. Denkel, S. F. Rouf, M. Rhen, F. C. Bange. 2010. Thiol peroxidase (Tpx) protects Salmonella enterica from hydrogen peroxide stress in vitro and facilitates intracellular growth. J. Bacteriol. 192(11):2929-32.

 

*Müsken, M., S. Di Fiore, U. Römling, S. Häussler. 2010. A 96-well plate based optical method for the quantitative and qualitative evaluation of Pseudomonas aeruginosa biofilm formation and its application for susceptibility testing. Nat. Protoc. 5:1460:1469.

 

Pommerenke, C., M. Müsken, T. Becker, A. Dötsch, F. Klawonn, S. Häussler. 2010. Global genotype-phenotype correlations in Pseudomonas aeruginosa. PLoS Pathog. 6(8):e1001074.

 

*Stegmann, K. A., N. K. Björkström, H. Veber, S. Ciesek, P. Riese, J. Wiegand, J. Hadem, P. V. Suneetha, J. Jaroszewicz, C. Wang, V. Schlaphoff, P. Fytili, M. Cronberg, M. P. Manns, R. Geffers, T. Pietschmann, C. A. Guzmán, H. G. Ljunggren, H. Wedemeyer. 2010. Interferon-a-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection. Gastroenterology. 138:1885-1897.

 

Thalmann, J.*, K. Janik*, M. May, K. Sommer, J. Ebeling, F. Hofmann, H. Genth, A. Klos. 2010. Actin reorganization induced by Chlamydia trachomatis Serovar D - Evidence for a critical role of the effector protein CT166 targeting Rac. PLoS ONE. 5:e9887. (* shared first authorship)

 

Duerr, C. U., S. F. Zenk, C. Chassin, J. Pott, D. Gütle, M. Hensel, M. W. Hornef. 2009. O-antigen delays lipopolysaccharide recognition and impairs antibacterial host defense in murine intestinal epithelial cells. PLoS Pathog. 5:e1000567.

 

Jeffe, F.*, K. A. Stegmann*, F. Broelsch, M. P. Manns, M. Cornberg, H. Wedemeyer 2009. Adenosine and IFN-alpha synergistically increase IFN-{gamma} production of human NK cells. J. Leukoc. Biol. 85:452-61. (* both authors contributed equally)

  

Jeron, A., S. Pfoertner, D. Bruder, R. Geffers, P. Hammerer, R. Hofmann, J. Buer, A. J. Schrader. 2009. Frequency and gene expression profile of regulatory T cells in renal cell carcinoma. Tumour Biol. 30:160-70.

 

*Littmann, M., B. Albiger, A. Frentzen, S. Normark, B. Henriques-Normark, L. Plant. 2009. Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression. EMBO Mol. Med. 1:211-22.

 

Malm, S., Y. Tiffert, J. Micklinghoff, S. Schultze, I. Joost, I. Weber, S. Horst, B. Ackermann, M. Schmidt, W. Wohlleben, S. Ehlers, R. Geffers, J. Reuther, F. C. Bange. 2009. The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis. Microbiology. 155:1332-9.

 

*Mosa, A., C. Trumstedt, E. Eriksson, O. Soehnlein, F. Heuts, K. Janik, A. Klos, O. Dittrich-Breiholz, M. Kracht, Å. Hidmark, H. Wigzell, M. E. Rottenberg. 2009. Nonhematopoietic cells control the outcome of infection with Listeria monocytogenes in a nucleotide oligomerization domain 1-dependent manner. Infect. Immun. 77:2908-18.

 

Müsken, M., S. Di Fiore, A. Dötsch, R. Fischer, S. Haussler. 2009. Genetic determinants of Pseudomonas aeruginosa biofilm establishment. Microbiology. 156(Pt 2):431-41.

 

Pott, J., T. Basler, C. U. Duerr, M. Rohde, R. Goethe, M. W. Hornef. 2009. Internalization-dependent recognition of Mycobacterium avium ssp. paratuberculosis by intestinal epithelial cells. Cell. Microbiol. 11:1802-15.

 

Probst-Kepper, M., R. Geffers, A. Kröger, N. Viegas, C. Erck, H. J. Hecht, H. Lünsdorf, R. Roubin, D. Moharregh-Khiabani, K. Wagner, F. Ocklenburg, A. Jeron, H. Garritsen, T. P. Arstila, E. Kekäläinen, R. Balling, H. Hauser, J. Buer, S. Weiss. 2009. GARP: a key receptor controlling FOXP3 in human regulatory T cells. J. Cell. Mol. Med. 13(9B):3343-57.

 

Schulz, T. F., S. Cordes. 2009. Is the Epstein-Barr virus EBNA-1 protein an oncogen? Proc. Natl. Acad. Sci. U S A. 106:2091-2.

 

*Stegemann, S., S. Dahlberg, A. Kröger, M. Gereke, D. Bruder, B. Henriques-Normark, M. Gunzer. 2009. Increased susceptibility for superinfection with Streptococcus pneumoniae during influenza virus infection is not caused by TLR7-mediated lymphopenia. PLoS ONE. 4:e4840.

 

Suneetha, P. V., V. Schlaphoff, C. Wang, K. A. Stegmann, P. Fytili, S. K. Sarin, M. P. Manns, M. Cornberg, H. Wedemeyer. 2009. Effect of peptide pools on effector functions of antigen-specific CD8+ T cells. J. Immunol. Methods. 342:33-48.

 

Trehanpati, N., R. Geffers, Sukriti, S. Hissar, P. Riese, T. Toepfer, J. Buer, M. Kumar, C. A. Guzman, S. K. Sarin. 2009. Gene expression signatures of peripheral CD4+ T cells clearly discriminate between patients with acute and chronic hepatitis B infection. Hepatology. 49:781-90.

 

*Voedisch, S., C. Koenecke, S. David, H. Herbrand, R. Förster, M. Rhen, O. Pabst. 2009. Mesenteric lymph nodes confine dendritic cell-mediated dissemination of Salmonella enterica serovar Typhimurium and limit systemic disease in mice. Infect. Immun. 77:3170-80.

 

Wang, C., A. Heim, V. Schlaphoff, P. V. Suneetha, K. A. Stegmann, H. Jiang, M. Krueger, P. Fytili, T. Schulz, M. Cornberg, R. Kandolf, M. P. Manns, C. T. Bock, H. Wedemeyer. 2009. Intrahepatic long-term persistence of parovirus B19 and its role in chronic viral hepatitis. J. Med. Virol. 81:2079-88.

 

Berberich, S., S. Dähne, A. Schippers, T. Peters, W. Müller, E. Kremmer, R. Förster, O. Pabst. 2008. Differential molecular and anatomical basis for B cell migration into the peritoneal cavity and omental milky spots. J. Immunol. 180:2196-2203.

 

*Ménard, S., V. Förster, M. Lotz, D. Gütle, C. U. Duerr, R. L. Gallo, B. Henriques-Normark, K. Pütsep, M. Andersson, E. O. Glocker, M. W. Hornef. 2008. Developmental switch of intestinal antimicrobial peptide expression. J. Exp. Med. 205:183-93.

 

*Yang, T., P. Stark, K. Janik, H. Wigzell, M. E. Rottenberg. 2008. SOCS-1 protects against Chlamydia pneumoniae-induced lethal inflammation but hampers effective bacterial clearance. J. Immunol. 180:4040-9.

 

Ebensen, T., C. Link, P. Riese, K. Schulze, M. Morr, C. A. Guzmán. 2007. A pegylated derivative of alpha-galactosylceramide exhibits improved biological properties. J. Immunol. 179:2065-73.

 

Ebensen, T., K. Schulze, P. Riese, C. Link, M. Morr, C. A. Guzman. 2007. The bacterial second messenger cyclic diGMP exhibits potent adjuvant properties. Vaccine. 25:1464-1469.

 

Ebensen, T., K. Schulze, P. Riese, M. Morr, C. A. Guzmán. 2007. The bacterial second messenger cdiGMP exhibits promising activity as a mucosal adjuvant. Clin. Vaccine Immunol. 14:952-8.

 

Halle, S., D. Bumann, H. Herbrand, Y. Willer, S. Dähne, R. Förster, O. Pabst. 2007. Solitary intestinal lymphoid tissue provides a productive port of entry for Salmonella enterica serovar Typhimurium. Infect. Immun. 75:1577-85.

 

Hansmeier, N., T. C. Chao, S. Daschkey, M. Müsken, J. Kalinowski, A. Pühler, A. Tauch. 2007. A comprehensive proteome map of the lipid-requiring nosocomial pathogen Corynebacterium jeikeium K411. Proteomics. 7:1076-96.

 

Schrader, A. J. , A. Hegele, P. Olbert, J. Buer, A. Jeron, R. Hofmann. 2007. [Application monitoring of the use of sorafenib in papillary renal cell carcinoma.] Urologe A. 46:1291. German.

 

Pfoertner, S., A. Jeron, M. Probst-Kepper, C. A. Guzman, W. Hansen, A. M. Westendorf, T. Toepfer, A. J. Schrader, A. Franzke, J. Buer, R. Geffers. 2006. Signatures of human regulatory T cells: an en­coun­ter with old friends and new players. Genome Biol. 7:R54.

 

 

Publications of ambassador students funded by MHH/HZI

names of ambassador graduate students are marked in bold;
asterisks indicate publications with authors from Swedish and German IRTG members

 

Reviewed publications

a) Scientific journals

 

Ahmad, I., S.F. Rouf, L. Sun, A. Cimdins, S. Shafeeq, S. Le Guyon, M. Schottkowski, M. Rhen, U. Römling. 2016. BcsZ inhibits biofilm phenotypes and promotes virulence by blocking cellulose production in Salmonella enterica serovar Typhimurium. Microb. Cell Fact. 15(1):177.

 

Del Bel Belluz, L., R. Guidi, I.S. Pateras, L. Levi, B. Mihaljevic, S.F. Rouf, M. Wrande, M. Candela, S. Turroni, C. Nastasi, C. Consolandi, C. Peano, T. Tebaldi, G. Viero, V.G. Gorgoulis, T. Krejsgaard, M. Rhen, T. Frisan. 2016. The typhoid toxin promotes host survival and the establishment of a persistent asymptomatic infection. PLoS Pathog. 12(4):e1005528.

 

Hentrich, K., J. Löfling, A. Pathak, V. Nizet, A. Varki, B. Henriques-Normark. 2016. Streptococcus pneumoniae senses a human-like sialic acid profile via the response regulator CiaR. Cell Host Microbe. 20(3):307-17.

 

Spelmink, L., V. Sender, K. Hentrich, T. Kuri, L. Plant, B. Henriques-Normark. 2016. TLR 3/TRIF-dependent IL-12p70 secretion mediated by Streptococcus pneumoniae RNA and its priming by influenza-A virus co-infection in human dendritic cells. MBio. 7(2). pii: e00168-16.

 

Xie, S., L. Spelmink, M. Codemo, K. Subramanian, K. Pütsep, B. Henriques-Normark, M. Olliver. 2016. Cinobufagin modulates human innate immune responses and triggers antibacterial activity. PLoS One. 11(8):e0160734.

 

Anwar, N., S.F. Rouf, U. Römling, M. Rhen. 2014. Modulation of biofilm-formation in Salmonella enterica serovar Typhimurium by the periplasmic DsbA/DsbB oxidoreductase system requires the GGDEF-EAL domain protein STM3615. PLoS One. 9(8):e106095.

 

*Lim, C.H., S. Voedisch, B. Wahl, S. F. Rouf, R. Geffers, M. Rhen, O. Pabst. 2014. Independent bottlenecks characterize colonization of systemic compartments and gut lymphoid tissue by salmonella. PLoS Pathog. 10(7):e1004270.

 

Schulte, T., J. Löfling, C. Mikaelsson, A. Kikhney, K. Hentrich, A. Diamante, C. Ebel, S. Normark, D. Svergun, B. Henriques-Normark, A. Achour. 2014. The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold. Open Biol.4:140172.

 

Guidi, R., L. Levi, S.F. Rouf, S. Puiac, M. Rhen, T. Frisan. 2013. Salmonella enterica delivers its genotoxin through outer membrane vesicles secreted from infected cells. Cell Microbiol. 15 (12): 2034-2050.

 

Olliver, M., L. Spelmink, J. Hiew, U. Meyer-Hoffert, B. Henriques-Normark, P. Bergman. 2013. Immunomodulatory effects of vitamin D on innate and adaptive immune responses to Streptococcus pneumoniae. J. Infect. Dis.  208(9):1474-81.

 

Monteiro, C., K. Papenfort, K. Hentrich, I. Ahmad, S. Le Guyon, R. Reimann, N. Grantcharova, U. Römling. 2012. Hfq and Hfq-dependent small RNAs are major contributors to multicellular development in Salmonella enterica serovar Typhimurium. RNA Biol. 489-502.

 


*Orrskog, S., S. Rounioja, T. Spadafina, M. Gallotta, M. Norman, K. Hentrich, S. Fälker, S. Ygberg-Eriksson, M. Hasenberg, KB. Johansson, L.M. Uotila, C. G. Gahmberg, M. Barocchi, M. Gunzer, S. Normark, B. Henriques-Normark. 2012. Pilus adhesin RrgA interacts with complement receptor 3, thereby affecting macrophage function and systemic pneumococcal disease. MBio. 4(1):e00535-12.

 

Cederlund, A., M. Olliver, R.S. Rekha, M. Lindh, L. Lindbom, S. Normark, B. Henriques-Normark, J. Andersson, B. Agerberth, P. Bergman. 2011. Impaired release of antimicrobial peptides into nasal fluid of hyper-IgE and CVID patients. PLoS One. 6(12):e29316.

 


Cederlund, A., M. Olliver, R.S. Rekha, M. Lindh, L. Lindbom, S. Normark, B. Henriques-Normark, J. Andersson, B. Agerberth, P. Bergman. 2011. Human monocytes promote Th1 and Th17 responses to Streptococcus pneumoniae. Infect. Immun. 79(10):4210-7.

 

*Denkel, L. A., S. A. Horst, S. F. Rouf, V. Kitowski, O. M. Böhm, M. Rhen, T. Jäger, F.-C. Bange. 2011. Methionine sulfoxide reductases are essential for virulence of Salmonella Typhimurium. PLoS. 6(11):e26974.

 

Rouf, S. F., I. Ahmad, N. Anwar, S. K. Vodnala, A. Kader, U. Römling, M. Rhen. 2011. Opposing contributions of polynucleotide phosphorylase and the membrane protein NlpI to biofilm formation by Salmonella enterica serovar Typhimurium. J. Bacteriol. 193(2):580-2.

 


Rouf, S. F., N. Anwar, M. O. Clements, M. Rhen. 2011. Genetic analysis of the pnp-deaD genetic region reveals membrane lipoprotein NlpI as an independent participant in cold acclimatization of Salmonella enterica serovar Typhimurium. FEMS Microbiol. Lett. 325(1):56-63

 

*Horst, S. A., T. Jaeger, L. Denkel, S. F. Rouf, M. Rhen, F. C. Bange. 2010. Thiol peroxidase (Tpx) protects Salmonella enterica from hydrogen peroxide stress in vitro and facilitates intracellular growth. J. Bacteriol. 192(11):2929-32.

 

Blomberg, C., J. Dagerhamn, S. Dahlberg, S. Browall, J. Fernebro, B. Albiger, E. Morfeldt, S. Normark, B. Henriques-Normark. 2009. Pattern of accessory regions and invasive disease potential in Streptococcus pneumoniae. J. Infect. Dis. 199:1032-1042.

 

Kline, K. A., S. Fälker, S. Dahlberg, S. Normark, B. Henriques-Normark. 2009. Bacterial adhesins in host-microbe interactions. Cell Host Microbe. 5(6):580-592. Review.

 

*Littmann, M., B. Albiger, A. Frentzen, S. Normark, B. Henriques-Normark, L. Plant. 2009. Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression. EMBO Mol. Med. 1(4):211-22.

 

*Stegemann, S., S. Dahlberg, A. Kröger, M. Gereke, D. Bruder, B. Henriques-Normark, M. Gunzer. 2009. Increased susceptibility for superinfection with Streptococcus pneumoniae during influenza virus infection is not caused by TLR7-mediated lymphopenia. PLoS ONE. 4(3):e4840.

 

Albiger, B., S. Dahlberg, B. Henriques-Normark, S. Normark. 2007. Role of the innate immune system in host defence against bacterial infections: Focus on the Toll-like receptors. J. Intern. Med. 261(6): 511-28. Review.

 

Albiger, B.*, S. Dahlberg*, A. Sandgren, F. Wartha, K. Beiter, H. Katsuragi, S. Akira, S. Normark, B. Henriques-Normark. 2007. Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection. Cell. Microbiol. 9(3):633-44. *Equal contribution

 

Nelson, A. L.*, J. Ries*, F. Bagnoli, S. Dahlberg, S. Fälker, S. Rounioja, J. Tschöp, E. Morfeldt, I. Ferlenghi, M. Hilleringmann, D. W. Holden, R. Rappuoli, S. Normark, M. A. Barrochi, B. Henriques Normark. 2007. RrgA is a pilus-associated adhesin in Streptococcus pneumoniae. Mol. Microbiol. 66(2):329-340. *Equal contribution

 

Barocchi, M. A.*, J. Ries*, X. Zogaj*, C. Hemsley, B. Albiger, A. Kanth, S. Dahlberg, J. Fernebro, M. Moschioni, V. Masignani, K. Hultenby, A. R. Taddei, K. Beiter, F. Wartha, A. von Euler, A. Covacci, D. W. Holden, S. Normark, R. Rappuoli, B. Henriques- Normark. 2006. A pneumococcal pilus influences virulence and host inflammatory responses. Proc. Natl. Acad. Sci. USA. 103(8):2857-62. *Equal contribution

 

 

Publications of (post-)doctoral students funded by other sources

names of (post-)doctoral students funded by other sources are marked in bold;
asterisks indicate publications with authors from Swedish and German IRTG members

 

Reviewed publications

a) Scientific journals

 

*Hengst, J., B. Strunz, K. Deterding, H.G. Ljunggren, E. Leeansyah, M.P. Manns, M. Cornberg, J.K. Sandberg, H. Wedemeyer, N.K. Björkström. 2016. Nonreversible MAIT cell-dysfunction in chronic hepatitis C virus infection despite successful interferon-free therapy. Eur. J. Immunol. 46(9):2204-10.

Spelmink, L., V. Sender, K. Hentrich, T. Kuri, L. Plant, B. Henriques-Normark. 2016. TLR 3/TRIF-dependent IL-12p70 secretion mediated by Streptococcus pneumoniae RNA and its priming by influenza-A virus co-infection in human dendritic cells. MBio. 7(2).

 

Xie, S., L. Spelmink, M. Codemo, K. Subramanian, K. Pütsep, B. Henriques-Normark, M. Olliver. 2016. Cinobufagin modulates human innate immune responses and triggers antibacterial activity. PLoS One. 11(8):e0160734.

 

Faber, E., E. Gripp, S. Maurischat, B. Kaspers, K. Tedin, S. Menz, A. Zuraw, O. Kershaw, I. Yang, S. Rautenschlein, C. Josenhans. 2015. Novel immunomodulatory flagellin-like protein flaC in Campylobacter jejuni and other campylobacteriales. mSphere. 1(1):e00028-15

 

*Hengst, J., J. Theorell, K. Deterding, A. Potthoff, A. Dettmer, H. G. Ljunggren, H. Wedemeyer, N.K. Björkström. 2015. High-resolution determination of human immune cell signatures from fine-needle liver aspirates. Eur. J. Immunol. 45(7):2154-7.

 

*Marquardt, N., V. Béziat, S. Nyström, J. Hengst, M.A. Ivarsson, E. Kekäläinen, H. Johansson, J. Mjösberg, M. Westgren, T.O. Lankisch, H. Wedemeyer, E.C. Ellis, H.G. Ljunggren, J. Michaëlsson, N.K. Björkström. 2015. Cutting Edge: Identification and characterization of human intrahepatic CD49a+ NK cells. J. Immunol. 194(6):2467-71.

 

*Berglin, L., A. Bergquist, H. Johansson, H. Glaumann, C. Jorns, S. Lunemann, H. Wedemeyer, E.C. Ellis, N.K. Björkström. 2014. In situ characterization of intrahepatic non-parenchymal cells in PSC reveals phenotypic patterns associated with disease severity. PLoS One. 9(8):e105375.

 

*Lunemann, S., D.F. Malone, J. Grabowski, K. Port, V. Béziat, B. Bremer, K.J. Malmberg, M.P. Manns, J.K. Sandberg, M. Cornberg, H.G. Ljunggren, H. Wedemeyer, N.K. Björkström. 2014. Effects of HDV infection and pegylated interferon α treatment on the natural killer cell compartment in chronically infected individuals. Gut. 64(3):469-82.

 

*Lunemann, S., D.F. Malone, J. Hengst, K. Port, J. Grabowski, K. Deterding, A. Markova, B. Bremer, V. Schlaphoff, M. Cornberg, M.P. Manns, J.K. Sandberg, H.G. Ljunggren, N.K. Björkström, H. Wedemeyer. 2013. Compromised function of natural killer cells in acute and chronic viral hepatitis. J. Infect. Dis. 209(9)1362-73.

 

Olliver, M., L. Spelmink, J. Hiew, U. Meyer-Hoffert, B. Henriques-Normark, P. Bergman. 2013. Immunomodulatory effects of vitamin D on innate and adaptive immune responses to Streptococcus pneumoniae. J. Infect. Dis.  208(9):1474-81.

 

Dang, L.V., A. Nilsson, H. Ingelman-Sundberg, A. Cagigi, L.B. Gelinck, K. Titanji, A. De Milito, S. Grutzmeier, J. Hedlund, F.P. Kroon, F. Chiodi. 2012. Soluble CD27 induces IgG production through activation of antigen-primed B cells. J. Intern. Med. 271(3):282-93.

 

*König, S., M. Nimtz, M. Scheiter, H.G. Ljunggren, Y.T. Bryceson, L. Jänsch. 2012. Kinome analysis of receptor-induced phosphorylation in human natural killer cells. PLoS One. 7(1):e29672.

 

*Stegmann, K. A., N. K. Björkström, S. Ciesek, S. Lunemann, J. Jaroszewicz, J. Wiegand, P. Malinski, L. B. Dustin, C. M. Rice, M. P. Manns, T. Pietschmann, M. Cornberg, HG. Ljunggren, H. Wedemeyer. 2012. Interferon α-stimulated natural killer cells from patients with acute Hepatitis C Virus (HCV) infection recognize HCV-infected and uninfected hepatoma cells via DNAX accessory molecule-1. J. Infect. Dis. 205(9):1351-62. 

 

Ahmad , I.*, A. Lamprokostopoulou*, S. Le Guyon, E. Streck, M. Barthel, V. Peters, W.D. Hardt, U. Römling. 2011. Complex c-di-GMP signalling networks mediate the transition between virulence properties and biofilm formation in Salmonella enterica serovar Typhimurium. PLoS One; 6(12):e28351.

 

Björkström, N.K., T. Lindgren, M. Stoltz, C. Fauriat, M. Braun, M. Evander J. Michaëlsson, K.J. Malmberg, J. Klingström, C. Ahlm, H.G. Ljunggren. 2011.  Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus. J. Exp. Med. 208(1):13-21.

 

Björkström, N.K., A. Svensson, K.J. Malmberg, K. Eriksson, H.G. Ljunggren. 2011. Characterization of natural killer cell phenotype and function during recurrent human HSV-2 infection. PLoS One 6(11):e27664.

 

Enqvist, M., G. Nilsonne, O. Hammarfjord, R.P.A. Wallin, N.K. Björkström,  M. Björnstedt, A. Hjerpe, H.G. Ljunggren, K. Dobra, K.J. Malmberg, M. Carlsten. 2011. Selenite induces post-transcriptional blockade of HLA-E expression and sensitizes tumor cells to CD94/NKG2A-positive natural killer cells. J. Immunol. 187(7):3546-54.

 

Gripp, E., D. Hlahla, X. Didelot, F. Kops, S. Maurischat, K. Tedin, T. Alter, L. Ellerbroek, K. Schreiber, D. Schomburg, T. Janssen, P. Bartholomaus, D. Hofreuter, S. Woltemate, M. Uhr, B. Brenneke, P. Gruening, G. Gerlach, L. Wieler, S. Suerbaum, C. Josenhans. 2011. Closely related Campylobacter jejuni strains from different sources reveal a generalist rather than a specialist lifestyle. BMC Genomics. 12(1):584.

 

Kuylenstierna C., N.K. Björkström, S.K. Andersson, P. Sahlström, L. Bosnjak, D. Paqui-Proulx, K.J. Malmberg, H. G. Ljunggren, M. Moll, J.K. Sandberg. 2011. NKG2D performs two functions in invariant NKT cells: Direct TCR-independent activation of NK-like cytolysis, and co-stimulation of activation by CD1d. Eur. J. Immunol. 41(7):1913-23.

 

Lindgren, T., C. Ahlm, N. Mohamed, M. Evander, H.G. Ljunggren, N.K. Björkström.  2011. Longitudinal analysis of the human T cell response during acute hantavirus infection. J. Virol. 85(19):10252-60.

 

Sammicheli , S., V.P. Dang, N. Ruffin, H.T. Pham, R. Lantto, N. Vivar, F. Chiodi, B. Rethi. 2011. IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway. PLoS One. 6(12):e28629.

 

    

Andres, S., A. Skoglund, C. Nilsson, M. Krabbe, B. Björkholm, L. Engstrand. 2010. Type I restriction-modification loci reveal high allelic diversity in clinical Helicobacter pylori isolates. Helicobacter. 15(2):114-125.

 

Björkström, N. K., C. Fauriat, Y. T. Bryceson, J. K. Sandberg, H. G. Ljunggren, K. J. Malmberg. 2010. Analysis of the KIR repertoire in human NK cells by flow cytometry. Methods Mol. Biol. 612:353-64.

 

Björkström, N.K., H.G. Ljunggren, J.K. Sandberg. 2010. CD56neg NK cells: Origin, function, and role in chronic viral disease. Trends Immunol. 31(11):401-6.

 

*Björkström, N.K., P. Riese, F. Heuts, S. Andersson, C. Fauriat, M. A. Ivarsson, A. T. Björklund, M. Flodström-Tullberg, J. Michaëlsson, M. E. Rottenberg, C. A. Guzmán, H.-G. Ljunggren, K.-J. Malmberg. 2010. Expression patterns of NKG2A, KIR and CD57 define a process of CD56dim NK cell differentiation uncoupled from NK cell education. Blood. 116(19):3853-64.

 

Bryceson, Y. T., C. Fauriat, J. Nunes, S. M. Wood, N. K. Björkström, E. O. Long, H. G. Ljunggren. 2010. Functional analysis of human NK cells by flow cytometry. Methods Mol. Biol. 612:335-52.

 

Daniels, R.*, P. Mellroth*, A. Bernsel *, F. Neiers, S. Normark, G. von Heijne, B. Henriques-Normark. 2010. Disulfide bond formation and cysteine exclusion in Gram-positive bacteria. J. Biol. Chem. 285(5):3300-9. * equal contribution.

 

Fasth, A. E. R., N. K. Björkström, M. Anthoni, K. J. Malmberg, V. Malmström. 2010. Activating NK cell receptors co-stimulate CD4+CD28-T cells in patients with rheumatoid arthritis. Eur. J. Immunol. 40(2):378-87.

 

Schmidt, H. M., S. Andres, C. Nilsson, Z. Kovach, N. O. Kaakoush, L. Engstrand, K.-L. Goh, K. M. Fock, D. Forman, H. Mitchell. 2010. The cag PAI is intact and functional but HP0521 varies significantly in Helicobacter pylori isolates from Singapore and Malaysia. Eur. J. Clin. Microbiol. Infect. Dis. 29(4):439-51.

 

Lamprokostopoulou, A., C. Monteiro, M. Rhen, U. Römling. 2010. C-di-GMP controls virulence properties of Salmonella enterica serovar Typhimurium at the mucosal lining. Environ. Microbiol. 12:40-53.

 

Römling, U., K. Jonas, Ö. Melefors, N. Grantcharova, A. Lamprokostopoulou. 2010. Hierarchical control of rdar morphotype development of Salmonella enterica by cyclic di-GMP. In: The second messenger cyclic di-GMP, A. J. Wolfe and K. L. Visick (eds.), ASM Press, Washington DC, USA, pp. 137-155. Review.

 

Rotzius, P., S. Thams, E. Kenne, O. Söhnlein, N.K. Björkström, K.J. Malmberg, L. Lindbo., E.E. Eriksson. 2010. Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice. Am. J. Pathol. 177(1):493-500.

 

Schmidt, H. M., S. Andres, C. Nilsson, Z. Kovach, N. O. Kaakoush, L. Engstrand, K.-L. Goh, K. M. Fock, D. Forman, H. Mitchell. 2010. The cag PAI is intact and functional but HP0521 varies significantly in Helicobacter pylori isolates from Singapore and Malaysia. Eur. J. Clin. Microbiol. Infect. Dis. 29(4):439-51.

 

*Stegmann, K. A., N. K. Björkström, H. Veber, S. Ciesek, P. Riese, J. Wiegand, J. Hadem, P. V. Suneetha, J. Jaroszewicz, C. Wang, V. Schlaphoff, P. Fytili, M. Cronberg, M. P. Manns, R. Geffers, T. Pietschmann, C. A. Guzmán, H. G. Ljunggren, H. Wedemeyer. 2010. Interferon-a-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection. Gastroenterology. 138:1885-1897.

 

Barkholt, L., E. Alici, R. Conrad, T. Sutlu, M. Gilljam, B. Stellan, B. Christensson, H. Guven, N. K. Björkström, G. Söderdahl, K. Cederlund, E. Kimby, J. Aschan, O. Ringdén, H. G. Ljunggren, M. S. Dilber. 2009. Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients: a Phase I clinical study. Immunotherapy. 1(5):753-764.

 

Cagigi, A., L. Du, L. V. Dang, S. Grutzmeier, A. Atlas, F. Chiodi, Q. Pan-Hammarström, A. Nilsson. 2009. CD27(-) B-cells produce class switched and somatically hyper-mutated antibodies during chronic HIV-1 infection. PLoS ONE. 4(5):e5427.

 

Grantcharova, N., V. Peters, C. Monteiro, K. Zakikhany, U. Römling. 2009. Bistable expression of CsgD in biofilm development of Salmonella enterica serovar Typhimurium. J. Bacteriol. 192(2):456-66.

 

Gonzalez, V. D., K. Falconer, N. K. Björkström, K. G. Blom, O. Weiland, H. G. Ljunggren, A. Alaeus, J. K. Sandberg. 2009. Expansion of functionally skewed CD56-negative NK cells in chronic HCV infection; Correlation with outcome of pegylated interferon-a and ribavirin treatment. J. Immunol. 183(10):6612-8.

 

Gruhne, B., R. Sompallae, M. G. Masucci. 2009. Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints. Oncogene. 28(45):3997-4008.

 

Gruhne, B., R. Sompallae, D. Marescotti, S. A. Kamranvar, S. Gastaldello, M. G. Masucci. 2009. The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species. Proc. Natl. Acad. Sci. U S A. 106(7):2313-8. 

 

Monteiro, C., I. Saxena, X. Wang, A. Kader, W. Bokranz, R. Simm, D. Nobles, M. Chromek, A. Brauner, R. Brown, U. Römling. 2009. Characterization of cellulose production in Escherichia coli Nissle 1917 and its biological consequences. Environ. Microbiol. 11(5):1105-16.

 

Puiac, S., A. Negrea, A. Richter-Dahlfors, L. Plant, M. Rhen. 2009. Omeprazole antagonizes virulence and inflammation in Salmonella enterica-infected RAW264.7 cells. Antimicrob. Agent. Chemother. 53:2402-2409.

 

Negrea, A., E. Bjur, S. Puiac, S.E. Ygberg, F. Åslund, M. Rhen. 2009. Thioredoxin 1 participates in the activity of Salmonella enterica serovar Typhimurium pathogenicity island 2 type III secretion system. J. Bacteriol. 191:6918-6927.

 

Rust, M., S. Borchert, E. Niehus, S. A. Kuehne, E. Gripp, A. Bajceta, J. L. McMurry, S. Suerbaum, K. T. Hughes, C. Josenhans. 2009. The Helicobacter pylori anti-sigma factor FlgM is predominantly cytoplasmic and cooperates with the flagellar basal body protein FlhA. J. Bacteriol. 191(15):4824-34.

 

Schmidt, H. M., S. Andres, N. O. Kaakoush, L. Engstrand, L. Eriksson, K. L. Goh, K. M. Fock, I. Hilmi, S. Dhamodaran, D. Forman, H. Mitchell. 2009. The prevalence of the duodenal ulcer promoting gene (dupA) in Helicobacter pylori isolates varies by ethnic group and is not universally associated with disease development: a case-control study. Gut Pathog. 1(1):5.

 

Ahlén, G., M. Weiland, E. Derk, J. Jiao, N. Rahbin, S. Aleman, D. L. Peterson, K. Pokrovskaja, D. Grandér, L. Frelin, M. Sällberg. 2008. Cleavage of the IPS-1/Cardif/MAVS/VISA does not inhibit T cell-mediated elimination of hepatitis C virus non-structural 3/4A-expressing hepatocytes. Gut. 58(4):560-9.

 

Ahlin, C., B. Gruhne, M. Holmqvist, A. Zetterberg, M. L. Fjällskog. 2008. Aberrant expression of cyclin E in low-risk node negative breast cancer. Acta Oncol. 47(8):1539-45.

 

Björkström, N. K., V. D. Gonzalez, K. J. Malmberg, K. Falconer, A. Alaeus, G. Nowak, C. Jorns, B. G. Ericzon, O. Weiland, J. K. Sandberg, H. G. Ljunggren. 2008. Elevated numbers of FcgRIIIA+ (CD16+) effector CD8 T cells with NK cell-like function in chronic hepatitis C virus infection. J. Immunol. 181(6):4219-28.

 

Bryceson, Y. T., H. G. Ljunggren. 2008. Tumor cell recognition by the NK cell activating receptor NKG2D. Eur. J. Immunol. 38:2957-2961.

 

Bryceson, Y. T., H. G. Ljunggren. 2008. Arrestin NK cell cytotoxicity. Nat. Immunol. 9:835-836.

 

Bryceson, Y. T., E. O. Long. 2008. Line of attack: NK cell specificity and integration of signals. Curr. Opin. Immunol. 20:344-352.

 

Cagigi, A., F. Mowafi, L. V. Phuong Dang, K. Tenner-Racz, A. Atlas, S. Grutzmeier, P. Racz, F. Chiodi, A. Nilsson. 2008. Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection. Blood. 112(12):4401-10.

 

Fauriat, C., S. Andersson, A. Björklund, M. Carlsten, M. Schaffer, N. K. Björkström, B. C. Baumann, J. Michaelsson, H. G. Ljunggren, K. J. Malmberg. 2008. Estimation of the size of the alloreactive NK cell repertoire: Studies in individuals homozygous for the group A KIR Haplotype. J. Immunol. 181(9):6010-9.

 

Gonzalez, V. D., N. K. Björkström, K. J. Malmberg, M. Moll, C. Kuylenstierna, J. Michaelsson, H. G. Ljunggren, J. K. Sandberg. 2008. Application of nine-color flow cytometry for detailed studies of the phenotypic complexity and functional heterogeneity of human lymphocyte subset. J. Immunol. Methods. 330(1-2):64-74.

 

Malmberg, K. J., Y. T. Bryceson, M. Carlsten, S. Andersson, A. Björklund, N. K. Björkström, B. C. Baumann, C. Fauriat, E. Alici, M. S. Dilber, H. G. Ljunggren. 2008. NK cell-mediated targeting of human cancer and possibilities for new means of immunotherapy. Cancer Immunol. Immunother. 57(10):1541-52.

 

Rudd, E., Y. T. Bryceson, C. Zheng, J. Edner, S. M. Wood, K. Göransdotter Ramme, A. Gurgey, M. Hellebostad, A. G. Bechensteen, H. G. Ljunggren, B. Fadeel, M. Nordenskjöld, J. I. Henter. 2008. Spectrum, and clinical and functional implications of UNC13D mutations in familial hemophagocytic lymphohistiocytosis. J. Med. Genet. 45:134-141.

 

Sompallae, R., S. Gastaldello, S. Hildebrand, N. Zinin, G. Hassink, K. Lindsten, J. Haas, B. Persson, M. G. Masucci. 2008. Epstein-Barr virus encodes three bona fide ubiquitin-specific proteases. J. Virol. 82(21):10477-86.

 

Sterzenbach, T., L. Bartonickova, W. Behrens, B. Brenneke, J. Schulze, F. Kops, E. Y. Chin, E. Katzowitsch, D. B. Schauer, J. G. Fox, S. Suerbaum, C. Josenhans. 2008. Role of the Helicobacter hepaticus flagellar sigma factor FliA in gene regulation and murine colonization. J. Bacteriol. 190(19):6398-408. [before the start of the Ph.D. thesis]

 

Carlsten, M., N. K. Björkström, H. Norell, Y. Bryceson, T. van Hall, B. C. Baumann, M. Hanson, K. Schedvins, R. Kiessling, H. G. Ljunggren, K. J. Malmberg. 2007. DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells. Cancer Res. 67(3):1317-25.

 

Coteur, G. P. Mellroth, C. De Lefortery, D. Gillian, P. Dubois, D. Communi, H. Steiner. 2007. Peptidoglycan recognition proteins with amidase activity in early deuterostomes (Echinodermata). Dev. Comp. Immunol. 31(8):790-804.

 

Fasth, A. E. R., O. Snir, A. A. T. Johansson, B. Nordmark, A. Rahbar, E. Af Klint, N. K. Björkström, A. K. Ulfgren, R. F. van Vollenhoven, V. Malmström, C. Trollmo. 2007. Skewed distribution of proinflammatory CD4+CD28null T cells in rheumatoid arthritis. Arthritis Res. Ther. 9:R87.

 

Kamranvar, S. A.*, * B. Gruhne*, A. Szeles, M. G. Masucci. 2007. Epstein-Barr virus promotes genomic instability in Burkitt's lymphoma. Oncogene. 26(35):5115-23. * equal contribution

 

Andrzejewska, J., S. K. Lee, P. Olbermann, N. Lotzing, E. Katzowitsch, B. Linz, M. Achtman, C. I. KadoI, S. Suerbaum, C. Josenhans. 2006. Characterization of the pilin ortholog of the Helicobacter pylori type IV cag pathogenicity apparatus, a surface-associated protein expressed during infection. J. Bacteriol. 188(16):5865-77. [before start of the Ph.D. thesis within the IRTG 1273]

 

Siegers, G. M., J. Yang, C. U. Duerr, P. J. Nielsen, M. Reth, W. W. Schamel. 2006. Identification of disulfide bonds in the Ig-alpha/Ig-beta component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system. Int. Immunol. 18(9):1385-96. [before start of the Ph.D. thesis within the IRTG 1273]

 

Wang, X., M. Rochon, A. Lamprokostopoulou, H. Lunsdorf, M. Nimtz, U. Römling. 2006. Impact of biofilm matrix components on interaction of commensal E. coli strain with the gastrointestinal cell line HT-29. Cell. Mol. Life Sci. 63(19-20):2352-63.

 

b) monographs

 

Louis, S., B. Gruhne, S. Mai. 2005. Towards an understanding of DNA replication in normal and cancer cells: facts and concepts. In: L. S. Peale (ed.) Progress in Oncogene Research, Chapter I, p. 1-56. Nova Science Publishers, Inc. Hauppauge, NY. Review.