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Prof. Dr. rer. nat. Claudia Grothe

Curriculum Vitae

 

 

Education

1981

Diploma in Biology, Free University of Berlin, Germany

1983

Dr. rer. nat., Free University of Berlin, Germany

1991

Habilitation in Anatomy and Cell Biology at the University of Marburg; Germany

1992

Privatdozent at the Philipps-University of Marburg; Germany

 

 

Academic Appointments:

1983-88

Postdoctorate, Inst. Anatomy & Cell Biology, University of Marburg, Germany

1988-92

Hochschulassistent (C1), Inst. Anatomy & Cell Biology, Marburg, Germany

1993-98

Professor (C3), Institute of Anatomy, University of Freiburg, Germany

since 1998

Professor (C4), Head of the Institute of Neuroanatomy, Hannover Medical School,  Hannover, Germany

 

 

 

 

Current research > Link  & Link 2 

 

 

 

Major Research Interests:

Neurotrophic factors

Neural stem cells

Cell and gene therapy

Neurode- and regeneration

Morbus Parkinson; peripheral nerve regeneration

.

 

 

 

Selected publications:

 

 

Jungnickel J, Brämer C, Bronzlik P, Lipokatic-Takacs E, Weinhold B, Gerardy-Schahn R, Grothe C. Level and localization of polysialic acid is critical for early peripheral nerve regeneration.

Mol Cell Neurosci. 2009 Mar;40(3):374-81.

Haile Y, Berski S, Dräger G, Nobre A, Stummeyer K, Gerardy-Schahn R, Grothe C. The effect of modified polysialic acid based hydrogels on the adhesion and viability of primary neurons and glial cells.

Biomaterials.2008 Apr;29(12):1880-91.

Haastert K, Mauritz C, Chaturvedi S, Grothe C. Human and rat adult Schwann cell cultures: fast and efficient enrichment and highly effective non-viral transfection protocol.

Nature Protocols 2007; 2(1): 99-104.

Timmer M, Cesnulevicius  K, Winkler C, Kolb J, Lipokatic-Takacs E, Jungnickel J, Grothe C. Fibroblast Growth Factor (FGF)-2 and FGF Receptor 3 are required for the development of the substantia nigra and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-Hydroxydopamine lesion.

J Neurosci. 2007 Jan 17;27(3):459-71.

Haile Y, Haastert K, Cesnulevicius K, Stummeyer K, Timmer M, Berski S, Dräger G, Gerardy-Schahn R, Grothe C. Culturing of glial and neuronal cells on polysialic acid.

Biomaterials. 2007 Feb;28(6):1163-73.

Cesnulevicius K, Timmer M, Wesemann M, Thomas T, Barkhausen T, Grothe C. Nucleofection is the most efficient nonviral transfection method for neuronal Stem Cells derived from vetral mesencephali with no changes in cell composition or dopaminergic fate.

Stem Cells. 2006 Dec;24(12):2776-91.

  

 

Contact:

 

Institute of Neuroanatomy, OE 4140

Building I3, Level H, Room 3080

Hannover Medical School

Carl-Neuberg-Str. 1

30625 Hannover, Germany

Phone: +49-511-532-2896

Fax: +49-511-532-2880

Mail: grothe.claudiamh-hannover.de

Web. www.mh-hannover.de/neuroanatomie.html

 

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