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Prof. Dr. med. vet. Kirsten Haastert-Talini

Curriculum Vitae


University entrance diploma Görres-Gymnasium, Düsseldorf


Academic studies-1    Biology  (intermediate diploma)  Heinrich-Heine-University, Düsseldorf


Academic studies-2    Veterinary medicine (state examination) University of Veterinary Medicine, Hannover


Doctorate.   Clinic for Neurosurgery, Hannover Medical School and Institute for Pharmacology, Toxicology and Pharmacy, University of Veterinary, Title: “In vitro- und In vivo-Studien zur Zellvitalität und Motoneuronenfraktion in ektopen Neuroimplantaten aus embryonalem Rattenrückenmark in Abhängigkeit von Gewinnungsmethoden und pharmakologischen Einflüssen” 

since 2002

Research Associate Institute of Neuroanatomy, Hannover Medical School


Research stay (07-10 2005) Department of Physiological Science & Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, USA (Prof. Fernando Gomez-Pinilla, DFG-research grant)


State doctorate    Specialism Anatomy 


Associate Professor, Institute of Neuroanatomy, Hannover Medical School



Current research > Link

Development of new therapeutic startegies to enhance peripheral nerve regeneration after massive substance loss

Selected Publications:


Stößel M, Rehra L, Haastert-Talini K (2017): Reflex-based grasping, skilled forelimb reaching, and electrodiagnostic evaluation for comprehensive analysis of functional recovery – the 7 mm rat median nerve gap repair model revisited. Brain and Behavior 2017 DOI: 10.1002/brb3.813

Stenberg L*, Stößel M*, Ronchi G, Geuna S, Yin Y, Mommert S, Martensson L, Metzen J, Grothe C, Dahlin LB*, Haastert-Talini K* (2017): Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides. *Contributed equally, BMC Neurosci  (2017) 18:53; DOI 10.1186/s12868-017-0374-z
Wuttke S, Zimpel A, Bein T, Braig S, Stoiber K, Vollmar A, Müller D, Haastert-Talini K, Schaeske J, Stiesch M, Zahn G, Mohmeyer A, Behrens P, Eickelberg O, Bölükbas DA and Meiners S (2017): Validating Metal-Organic Framework Nanoparticles for Their Nanosafety in Diverse Biomedical Applications. Adv Healthc Mater 2017;6(2). doi: 10.1002/adhm.201600818.

van Neerven SG, Haastert-Talini K, Boecker A, Schriever T, Dabhi C, Claeys K, Deumens R, Brook GA, Weis J, Pallua N and Bozkurt A (2016): Two-component collagen nerve guides support axonal regeneration in the rat peripheral nerve injury model. J Tissue Eng Regen Med. 2016 Dec 16. doi: 10.1002/term.2248.

Meyer C*, Stenberg L*, Gonzalez-Perez F*, Wrobel S, Ronchi G, Udina E, Suganuma S, Geuna S, Navarro X, Dahlin LB, Grothe C, Haastert-Talini K (2016): Chitosan-film enhanced chitosan nerve guides for long-distance regeneration of peripheral nerves. Biomaterials. 2016 Jan;76:33-51. doi: 10.1016/j.biomaterials.2015.10.040.,

Meyer C*,Wrobel S*, Raimondo S, Rochkind S, Heimann C, Shahar A, Ziv-Polat O, Geuna S, Grothe C, Haastert-Talini K (2016): Peripheral nerve regeneration through hydrogel enriched chitosan tubes containing engineered Schwann cells for drug delivery. Cell Transplant. 2016;25(1):159-82. doi: 10.3727/096368915X688010.

Wrobel, S., Serra, S.C., Ribeiro-Samy, S., Sousa, N., Heimann, C., Barwig, C., Grothe, C., Salgado, A.J., Haastert-Talini, K. (2014): In vitro cell-seeded chitosan films for peripheral nerve tissue engineering. Tissue Engineering Part A 20(17-18):2339-49.

Morano, M., Wrobel, S., Fregnan, F., Ziv-Polat, O., Shahar, A., Geuna, S., Grothe, C., Haastert-Talini, K. (2014):  Nanotechnology versus stem cell engineering - In vitro-comparison of neurite inductive potentials. Int J Nanomedicine 9(1):5289-5306

Haastert-Talini, K., Geuna, S., Dahlin, L. B., Meyer, C., Stenberg, L., Freier, T., Heimann, C., Barwig, C.,  Pinto, L. F.V., Raimondo, S., Gambarotta, G., Samy, S. R., Sousa, N., Salgado, A. J., Ratzka, A., Wrobel, S., Grothe, C. (2013): Chitosan tubes of varying degrees of acetylation for bridging peripheral nerve defects. Biomaterials 34(38):9886-904

Mensching, L., Börger, A.K., Wang, X., Charalambous, P., Unsicker, K., Haastert-Talini K (2012): Local substitution of GDF-15 improves axonal and sensory recovery after peripheral nerve injury.
Cell Tissue Res 350(2):225-238

Huelsenbeck, S.C., Rohrbeck, A., Handreck, A., Hellmich, G., Kiaei, E., Roettinger, I., Grothe, C., Just, I., Haastert Talini, K. (2011): C3 peptide promotes axonal regeneration and functional motor recovery after peripheral nerve injury. Neurotherapeutics 9: 185-198.

Haastert-Talini, K.
, Schmitte, R., Korte, N., Klode, D., Ratzka, A., Grothe, C. (2011): Electrical stimulation accelerates axonal and functional peripheral nerve regeneration across long gaps. J Neurotrauma 28(4):661-74

Haastert-Talini K, Schaper-Rinkel J, Schmitte R, Rode b, Mühlenhoff M, Schwarzer D, Dräger G, Su Y, Scheper T, Gerardy-Schahn R, Grothe C. (2010): In vivo evaluation of polysialic acid as part of tissue-engineered nerve transplants. Tissue Eng Part A. 2010 Jun 24.

Haastert K
, Joswig H, Jäschke KA, Samii M, Grothe C (2010): Nerve repair by end-to-side nerve coaptation - histological and morphometrical evaluation of axonal origin and functionality in a sciatic nerve model in rats. Neurosurgery 2010 Mar;66(3):567-77.

Schmitte R, Tipold A, Stein VM, Schenk H, Flieshardt C, Grothe C, Haastert K (2010): Genetically modified canine Schwann cells - in vitro and in vivo evaluation of their suitability for peripheral nerve tissue engineering.  J Neurosci Methods 2010 Feb;186(2):202-208

Haastert K, Ying Z, Grothe C, Gómez-Pinilla F (2008): The effects of FGF-2 gene therapy combined with voluntary exercise on axonal regeneration across peripheral nerve gaps. Neurosci Lett 443(3):179-83.

Haastert K, Mauritz C, Chaturvedi S, Grothe C (2007): Adult human and rat Schwann cell cultures - fast and efficient enrichment and highly effective non-viral transfection protocol. Nature Protocols 2 (1), 99-104.

Books and Book Chapters:

Haastert-Talini, Kirsten, Assmus, Hans, Antoniadis, Gregor (Eds.):  Modern Concepts of Peripheral Nerve Repair. Springer-Verlag GmbH, Heidelberg, 2017

Ahmet Bozkurt, Kirsten Haastert-Talini (2014) Kapitel 10: Bioartifizielle Nervenimplantate und alternative Rekonstruktionsverfahren. In: Nervenchirurgie: Trauma, Tumor, Kompression (Kretschmer, Antoniadis, Assmus,eds), Springer Verlag Berlin Heidelberg

Stefano Geuna, Kirsten Haastert-Talini, Xavier Navarro (2013) Chapter 4-1: The Nerve Trunk in Injury and During Regeneration. In: Current Treatment of Nerve Injuries and Disorders (Dahlin LB, Leblebicioglu G, eds), Federation of European Societies for Surgery of the Hand, Instructional Courses 2013, Palme Publications

Kirsten Haastert-Talini (2012) Chapter 17: Culture and proliferation of highly purified Schwann cells from rat, dog and man. Methods Mol Biol 2012; 846:189-200.
Kirsten Haastert-Talini (2011) Chapter 10: Experimental Approaches on Tissue engineering Repair of Peripheral Nerve Gaps. In: The Sciatic Nerve: Blocks, Injuries and Regeneration (Fonseca DJ, Martins JL, eds); Series: Neuroscience Research Progress: Nove Science Publishers  Link





Prof. Dr. med. vet. Kirsten Haastert-Talini
Institute of Neuroanatomy and Cell Biology, OE 4140  
Building I3, Level H, Room 3110  
Hannover Medical School
Carl-Neuberg-Str. 1  
30625 Hannover, Germany  
Phone: +49-511-532-2891  
Fax: +49-511-532-2880