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2009

Dreger SC, Schulz F, Huelsenbeck J, Gerhard R, Hofmann F, Just I, Genth H.

Killing of Rat Basophilic Leukemia Cells by Lethal Toxin from Clostridium sordellii: Critical Role of Phosphatidylinositide 3'-OH Kinase/Akt Signaling

Biochemistry 2009;6 

Abstract

  

Andresen H, Bingel U, Streichert T, Schmoldt A, Zörner A, Tsikas D, Just I.

Severe glycerol intoxication after Menière's disease diagnostic - case report and overview of kinetic data.

Clinical Toxicology 2009;47;312-316

Abstract

 

Nerlich A, Rohde M, Talay SR, Genth H, Just I, Chhatwal GS.

Invasion of Endothelial Cells by Tissue-invasive M3 Type Group A Streptococci Requires Src Kinase and Activation of Rac1 by a Phosphatidylinositol 3-Kinase-independent Mechanism.

J Biol Chem 2009;284(30);20319-20328

Abstract

 

Sun X, He X, Tzipori S, Gerhard R, Feng H.

Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-α by macrophages.

Microbial Pathogenesis 2009;46;298-305

Abstract

 

Schoentaube J, Olling A, Tatge H, Just I, Gerhard R.

Serine-71-phosphorylation of Rac1/Cdc42 diminshes the pathogenic effect of Clostridium difficile toxin A.

Cell Microbiol 2009;11(12);1816-1826

Abstract

 

Schulz F, Just I, Genth H.

Prevention of Clostridium sordellii Lethal Toxininduced apoptotic cell death by Tauroursodeoxycholic Acid.

Biochemistry 2009;48(38),9002-9010

Abstract

 

Deplazes J, Fuchs M, Rauser S, Genth H, Lengyel E, Luber B.

Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.

Hum Mol Genet 2009;18(19);3632-3644

Abstract

 

Hülsenbeck SC, May M, Schmidt G, Genth H.

Inhibition of cytokinesis by Clostridium difficile toxin B and cytotoxic necrotizing factors-reinforcing the critical role of RhoA in cytokinesis.

Cell Motil Cytoskeleton 2009;66(11);967-975

Abstract

 

Lange O, Bigalke H, Dengler R, Wegner F, deGroot M, Wohlfarth K.

Neutralilzing antibodies and secondara therapy failure after treatment with botulinum toxin type A: much ado about nothing?

Clin Neurophamacol 2009;32(4);213-218

Abstract 

 

Rummel A, Häfner K, Mahrhold S, Darashchonak N, Holt M, Jahn R, Beerman S, Karnath T, Bigalke H, Binz T.

Botulinum neurotoxins C, E and F bind gangliosides vis a conserverd binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoformes of SV2 als second rezeptor.

J Neurochem 2009;110(6);1942-1954

Abstract

 

Mohammadi B, Buhr N, Bigalke H, Krampfl K, Dengler R, Kollewe K.

A long-term follow-up of botulinum toxin A in cervical dystonia.

Neurol Res 2009;32(5);463-466

Abstract

 

Mohammadi B, Kollewe K, Wegener M, Bigalke H, Dengler R.

Experience with long-term treatment with albumin-supplement botulinum toxin type A.

J Neural Transm 2009;116(4);437-441

Abstract

 

Lange O, Bigalke H, Dengler R, Wegner F, deGroot M, Wohlfarth K.

Neutralizing antibodies and secondary therapy failure after treatment with botulinum toxin type A: much ado about nothing?

Clin Neuropharmacol 2009;32(4);213-218

Abstract

 

Kotz A, Wagner J, Engel J, Routier F, Echternacher B; Pich A, Rhode M, Hoffmann P, Heesemann J, Ebel F.

The mitA gene of Aspergillus fumigatus ist required for mannosylation of inositol-phosphorylceramide, but is dispensable for pathogenicity.

Fungal Genet Biol 2009;47(2);169-178

Abstract

 

Hülsenbeck SC, Klose I, Reichenbach M, Hülsenbeck J, Genth H.

Distinct kinetics of (H/K/N)Ras gluscoylation and Rac1 glucosylation catalysed by Clostridium sordellii toxin.

FEBS Lett 2009;593(19);3133-3139

Abstract

 

Binz T, Rummel A.

Cell entry strategy of clostridial neurotoxins.

J Neurochem 2009;109(6);1584-1595

Abstract

 

von Witzendorff, Maass K, Pich A, Ebeling S, Kölle S, Kochel C.

Characterization of the acidic N-linked glycans of the zona pellucida of prepuberal pigs by a mass spectrometric approach.

Carbohydr Res 2009;344(129;1541-1549

Abstract

 

Brunger AT, Rummel A.

Receptor and substrate interations of clostridial neurotoxins.

Toxicon 2009;54(5);550-560

Abstract

 

Genth H, Schulz F, Just I.

Glucosylation of Rho/Ras Proteins by Lethal Toxin - Implications of Actin-Re-Organization and Apoptosis in C. Sordellii-Associated Disease.

The Open Toxinology Journal 2009;2

Abstract

 

Just I, Hülsenbeck SC, Genth H.

Clostridium Botulinum C3 Exoenzyme: Rho-Inactivating Tool in Cell Biology and an Neurothrophic Agent.

The Open Toxinology Journal 2009;2

Abstract