Dr. Wiebke Schaper
Dr. rer. nat.
Diplom-Biochemikerin
Post-Doc
Geb. J3, Ebene 04, Raum 2030 oder
Tel.: +49(0)511/532-5213 oder -9302
FAX: +49(0)511/532-8801
E-Mail: Schaper.Wiebke(at)mh-hannover.de
Research interests
CMP-Sialic acid synthetase (CMAS)
Biochemical characterisation of sialic acid activating enzymes from different species
Publications
Oschlies, M.; Dickmanns, A.; Haselhorst, T.; Schaper, W.; Stummeyer, K.; Tiralongo, J.; Weinhold, B.; Gerardy-Schahn, R.; von Itzstein, M.; Ficner, R. ; Münster-Kühnel, A.-K., (2009) A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme. J. Mol. Biol. 393(1):83–97.
Haselhorst, T., Stummeyer, K., Mühlenhoff, M., Schaper, W., Gerardy-Schahn, R., and von Itzstein, M. (2006) Endosialidase NF Appears To Bind PolySia DP5 in a Helical Conformation. Chembiochem. 7(12):1875-7.
PhD thesis/dissertation (June 2007 – May 2011)
Biochemical Characterization of Vertebrate CMP-Sialic Acid Synthetases and Functional Analysis in Early Zebrafish Development