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European Doctoral Academy in Regenerative Engineering

Marie Curie Initial Training Network TECAS: Tissue Engineering for Cardiovascular Surgery

Open Vacancy new!

The TECAS-ITN is looking to recruit a highly motivated Early Stage Research Fellow for the project ESR11, Preservation methods for cell-seeded TE cardiovascular grafts, based at the University of Padua, Italy.  

 

Overview

The TECAS Initial Training Network (TECAS-ITN) integrates the major European investigators and experts in the field of cardiovascular tissue engineering (TE) and regenerative medicine (RM), with a view to establishing a European Doctoral Academy in Regenerative Engineering. The aim of the Doctoral Academy is to facilitate the cross-disciplinary and intersectorial training of Early Stage Researchers (ESRs) in the field, by consolidating the extensive multidisciplinary experience in training and research of its academic, clinical and industrial Partners. The TECAS-ITN focuses on the clinical needs of cardiac valve replacement/repair, myocardium reconstruction and patch graft angioplasty of the great blood vessels, with a view to developing the underpinning expertise and technology for manufacturing cardiovascular TE implants for clinical use. The TECAS-ITN will host 13 Marie Currie ESR Fellows at 6 different Partner Institutions, each performing an individual research project that is placed along the innovation pipeline of a number of TE products/technologies from basic science to translational research.

 

 

Fellowship Description

Title: Preservation methods for cell-seeded TE cardiovascular grafts (ESR11)

 

Summary: This Fellowship opening covers a 2+1 year research position (resulting in a PhD degree) at University of Padua, Padua, Italy. The main part of this Fellowship will be carried out at the Department of Cardiac, Thoracic and Vascular Sciences.

 

Description: The aim of this Fellowship is to evaluate a range of preservation methods, commonly used by tissues banks for medium- to long-term storage of transplants, on cell-seeded TE constructs, with a view to establishing optimal preservation methods for TE grafts. This Fellowship will research cell-seeded TE scaffolds obtained from pulmonary and aortic valve roots (human and porcine), small intestine (porcine) and pericardium (porcine/bovine), which will be decellularised according to previously-established methods, and ovine fibrin valvular scaffolds, which will be contributed by another ESR project within the TECAS-ITN. The scaffolds will be seeded statically with single and multiple human cell populations under previously-established optimal seeding conditions, and will be assessed in terms of cell viability, attachment, colonisation, and phenotype. The seeded scaffolds will then be treated with a range of different preservation techniques and assessed in terms of cell viability and phenotype in order to identify the most suitable techniques and parameters for the particular scaffold/cell combinations.

 

Research Field: Cardiovascular tissue engineering and regenerative medicine

 

Keywords: Preservation methods, cardiovascular scaffolds and TE constructs, heart valves, cardiovascular patches

 

Collaborators: Hannover Medical School, RWTH Aachen University and Hospital

 

Supervision: Prof. Gino Gerosa (PI), Dr. Paola Aguiari (co-I), Dr. Sotirios Korossis (co-I), Prof. Stefan Jockenhövel (co-I)

 

Type of Contract: Temporary (22 + 14 months)

 

Status: Full‐time (40 hours/week)

 

Salary: 38,000 (gross) per annum plus mobility and career development allowances and full tuition fees will be offered by the TECAS-ITN for the first part of the contract. The second part of the contract will be financed by the University of Padua according to the national rules on the remuneration of doctoral researchers.

 

Person Specification

Required Degree: Master’s Degree (or equivalent) in Biology, Biochemistry, Biomedical Engineering or Medicine (or related subject)

Required Languages: English (Excellent)

Eligibility: The Fellowship is open to international candidates, who at the time of recruitment have less than 4 years research experience (full-time equivalent) following completion of their Master’s Degree (or equivalent), and have not yet been awarded a doctoral degree. Eligible candidates must also not have resided or carried their main activity in Italy for more than 12 months since October 2011.

 

Hosting Institution

Company/Institute: University of Padua

Department: Department of Cardiac, Thoracic and Vascular Sciences

City/Country: Padua, Italy

Academic Contact: Professor Gino Gerosa (Email: gino.gerosaunipd.it; Tel: + 39 049 821 2410-35)

 

Code of Conduct

The TECAS-ITN adheres to the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers, available from: http://ec.europa.eu/research/era/docs/en/areas-of-action-research-institutions-european-charter-2005.pdf .

 

Applications Details

 

Application Deadline: 31st August 2014

Indicative Post Starting Date: 1st October 2014

How to Apply: Please visit our website download and fill the application form, and email it, together with your full CV, in a PDF-file format to:

 

Miss Eirini Chatzigeorgiou

TECAS-ITN Research Manager

Email: Chatzigeorgiou.Eirinimh-hannover.de       Tel: +49 511 532 7798

 

For more information, please visit:

http://doctoralacademy.mh-hannover.de

 

 

Partner Institutions

The TECAS-ITN is a consortium of 5 academic/clinical, 2 industrial and 1 regulatory agency Partners with wide expertise in basic science, clinical research, translation and standardisation of TE technologies:

Hannover Medical School (Coordinator)

RWTH Aachen University and Hospital

Eindhoven University of Technology

University of Padua

University of Patras

Corlife GbR

Textile Technology Transfer GmbH

British Standards Institute

 

Research Training

In addition to their research projects, the training of the Doctoral Fellows will be complemented by project-specific Exchange secondments to other TECAS-ITN Partners collaborating on a specific Fellowship, Clinical secondments to the organ banks of the clinical Partners, Industrial secondment to the industrial Partners and Laboratory secondments to academic institution outside TECAS-ITN, as well as through an extensive curriculum of academic and transferable skills courses and workshops, and public engagement activities. The Fellows will also be awarded specialist certificates, based on their individual training, which will be recognised and endorsed by all academic and industrial Partners.

 

There were 2 rounds of recruitment for the 13 Doctoral Fellowships. The application deadline for the first cohort of Fellowships was the 31st of March 2013, whereas the application deadline for the second cohort of Fellowships was the 30th June 2013

 

 

 

 

 

 

 

Further Enquiries

TECAS-ITN & European Doctoral Academy Director

Dr Sotiris Korossis

Lower Saxony Centre for Biomedical Engineering, Implant Research and Development

Department of Cardiothoracic, Transplantation and Vascular Surgery

Hannover Medical School

Feodor-Lynen-Straße 31, Hannover, 30625, Germany

Tel: +49 511 532 8258

Email: korossis.sotiriosmh-hannover.de

 


Letzte Änderung:  06.Aug.2014.