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Dr. Iris Röckle

 

Dr. rer. nat.

Diplom-Biologin

Post-Doc

 

Geb. J3, Ebene 04, Raum 1060

Tel.: +49(0)511/532-3367

FAX: +49(0)511/532-8801

 

E-Mail: Roeckle.Iris(at)mh-hannover.de

 

 

 

Research interests

 

Role of polysialic acid and NCAM in interneuron development.

 

 

Publications

 

Schiff M., Röckle I., Burkhardt H., Weinhold B., Hildebrandt H. (2011) Thalamocortical pathfinding defects precede degeneration of the reticular thalamic nucleus in polysialic acid-deficient mice. J Neurosci. 31(4):1302-12.

 

Nacher J., Guirado R., Varea E., Alonso-Llosa G., Röckle I., Hildebrandt H. (2010) Divergent impact of the polysialyltransferases ST8SiaII and ST8SiaIV on polysialic acid expression in immature neurons and interneurons of the adult cerebral cortex. Neuroscience. 167(3):825-37.

 

Hildebrandt H., Mühlenhoff M., Oltmann-Norden I., Röckle I., Burkhardt H., Weinhold B., Gerardy-Schahn R. (2009) Imbalance of neural cell adhesion molecule and polysialyltransferase alleles causes defective brain connectivity. Brain. 132(Pt 10):2831-8.

 

Röckle I., Seidenfaden R., Weinhold B., Mühlenhoff M., Gerardy-Schahn R., Hildebrandt H. (2008) Polysialic acid controls NCAM-induced differentiation of neuronal precursors into calretinin-positive olfactory bulb interneurons. Dev Neurobiol. 68(9):1170-84.

 

Weinhold B., Seidenfaden R., Röckle I., Mühlenhoff M., Schertzinger F., Conzelmann S., Marth J.D., Gerardy-Schahn R., Hildebrandt H. (2005) Genetic ablation of polysialic acid causes severe neurodevelopmental defects rescued by deletion of the neural cell adhesion molecule. J Biol Chem. 280(52):42971-7.