Dr. Angel Ashikov

 

Ph.D.

Molecular biology

Postdoctoral researcher 

 

Building I3, Level 04, Room 1300 or 1250

Tel.: +49(0)511/532-8303 or -9806

FAX: +49(0)511/532-8801

 

E-Mail: ashikov.angel(at)mh-hannover.de

 

 

 

Research interests

 

- Nucleotide-sugar transporters

 

- Golgi and Endoplasmic Reticulum transport

 

 

 

 

Publications

 

Sethi MK., Buettner FF., Ashikov A., Krylov VB., Takeuchi H., Nifantiev NE., Haltiwanger RS., Gerardy-Schahn R., and Bakker H. (2012) Molecular Cloning of a Xylosyltransferase that Transfers the Second Xylose to O-Glucosylated Epidermal Growth Factor Repeats of Notch. J Biol Chem. 287(4):2739-48. 

 

Boztug K., Appaswamy G., Ashikov A., Schäffer AA., Salzer U., Diestelhorst J., Germeshausen M., Brandes G., Lee-Gossler J., Noyan F., Gatzke AK., Minkov M., Greil J., Kratz C., Petropoulou T., Pellier I., Bellanné-Chantelot C., Rezaei N., Mönkemöller K., Irani-Hakimeh N., Bakker H., Gerardy-Schahn R., Zeidler C., Grimbacher B., Welte K., and Klein C. (2009) A syndrome with congenital neutropenia and mutations in G6PC3. N Engl J Med. 360(1):32-43. Erratum in: N Engl J Med. 2011;364(17):1682.

 

Bakker H., Oka T., Ashikov A., Yadav A., Berger M., Rana NA., Bai X., Jigami Y., Haltiwanger RS., Esko JD., and Gerardy-Schahn R. (2009) Functional UDP-xylose transport across the endoplasmic reticulum/Golgi membrane in a Chinese hamster ovary cell mutant defective in UDP-xylose Synthase. J Biol Chem. 284(4):2576-83. 

 

Bakker H., Routier F., Ashikov A., Neumann D., Bosch D., and Gerardy-Schahn R. (2008) A CMP-sialic acid transporter cloned from Arabidopsis thaliana. Carbohydr Res. 343(12):2148-52. 

 

Tiralongo J., Ashikov A., Routier F., Eckhardt M., Bakker H., Gerardy-Schahn R., and von Itzstein M. (2006) Functional expression of the CMP-sialic acid transporter in Escherichia coli and its identification as a simple mobile carrier. Glycobiology. 16(1):73-81. 

 

Kabuss R., Ashikov A., Oelmann S., Gerardy-Schahn R., and Bakker H. (2005) Endoplasmic reticulum retention of the large splice variant of the UDP-galactose transporter is caused by a dilysine motif. Glycobiology. 15(10):905-11. 

 

Ashikov A., Routier F., Fuhlrott J., Helmus Y., Wild M., Gerardy-Schahn R., and Bakker H. (2005) The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine. J Biol Chem. 280(29):27230-5. 

 

Todorova A., Ashikov A., Beltcheva O., Tournev I, and Kremensky I. (1999) C283Y mutation and other C-terminal nucleotide changes in the gamma-sarcoglycan gene in the Bulgarian Gypsy population. Hum Mutat. 14(1):40-4. Erratum in: Hum Mutat. 2000;15(5):479.