Publications

Benedito R., Roca C., Sörensen I., Adams S., Gossler A., Fruttiger M. and Adams R.H. (2009). The Notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 137, 1124-1135

Sörensen, I., Adam, R., and Gossler, A. (2009). DLL1 mediated Notch activation regulates endothelial identity in mouse fetal arteries. Blood, 113, 5680-5688

Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development. (2009). Schuster-Gossler K., Harris B., Johnson KR., Serth J. and Gossler A. BMC Dev Biol. 2009 Jan 22;9:6

Feyerabend TB, Terszowski G, Tietz A, Blum C, Luche H, Gossler A, Gale NW, Radtke F, Fehling HJ, and Rodewald HR. (2009). Deletion of Notch1 Converts Pro-T Cells to Dendritic Cells and Promotes Thymic B Cells by Cell-Extrinsic and Cell-Intrinsic Mechanisms. Immunity, 30, 67-79.

Rocha SF., Lopes SS., Gossler A., Henrique D. (2009). Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity. Developmental Biology, 328, 54-65

Feller J., Schneider A., Schuster-Gossler K., and Gossler A. (2008). Non-cyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation. Genes and Development, 22, 2166-2171.

Estrach S., Cordes R., Hozumi K., Gossler A., and Watt FM. (2008). Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis. The Journal of Investigative Dermatology, 128, 825-832.

Schuster-Gossler K., Cordes R. and Gossler A. (2007). Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants. PNAS, 104, 537-542.

Limbourg A., Ploom M., Elligsen D., Sörensen I., Ziegelhoeffer T., Gossler A., Drexler H. and Limbourg F. P. (2007) The Notch Ligand Delta-like 1 (Dll1) is Essential for Postnatal Arteriogenesis. Circ. Res., 100, 363-371.

Cheng H-T., Kim M., Valerius M.T., Surendran K., Schuster-Gossler K., Gossler A., McMahon A.P.and Kopan R. (2007) Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development, 134, 801-811.

Geffers I., Serth K., Chapman G., Jaekel R., Schuster-Gossler K., Cordes R., Sparrow D.B., Kremmer E., Dunwoodie S.L., Klein T., and Gossler A. (2007). Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo. The Journal of Cell Biology, 178, 465-476.

Wittler L., Shin E., GroteP., Kispert A., Beckers A., Gossler A., Werber M, and Herrmann B. G. (2007). Expression of Msgn1 in the presomitic mesoderm is controlled by synergism of WNT signaling and Tbx6. EMBO Reports, 8, 784-789.

Teppner I., Becker S., Hrabe de Angelis, M. Gossler A., and Beckers J. (2007). Compartmentalised expression of Delta-like 1 in epithelial somites is required for the formation of intervertebral joints. BMC Developmental Biology 7:68 (17 June 2007)

Beckers A., Alten L., Viebahn C., Andre P. and Gossler A. (2007). The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left-right patterning. PNAS, 104, 15765–15770.

Yojiro Yamanaka Y., Tamplin O.J., Beckers A., Gossler A., and Rossant J. (2007). A changing genetic hierarchy regulates morphogenesis in three regions of the mouse notochord. Dev. Cell, 13, 884-896.

Sekita Y., Wagatsuma H., Irie M., Kobayashi S., Kohda T., Matsuda J., Yokoyama M., Ogura A., Schuster-Gossler K., Gossler A., Ishino F. and Kaneko-Ishino T. (2006) Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenetic and Genome Research, 113, 223-229.

Schröder N., Sekhar A., Geffers I., Müller J., Dittrich-Breiholz O., Kracht M., Wedemeyer J. and Gossler A. (2006). Identification of mouse genes with highly specific expression patterns in differentiated intestinal epithelium. Gastroenterology, 130, 902-907.

Mizuguchi R., Kriks S., Cordes R., Gossler A., Ma Q., and Goulding M. (2006). Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons. Nat Neurosci., 9, 770-778.

Ji SJ, Zhuang B., Falco C., Schneider A., Schuster-Gossler K., Gossler A., and Sockanathan S. (2006) Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons. Dev Biol, 297, 249-61.

Castro D.S., Skowronska-Krawczyk D., Armant O., Donaldson I.J., Parras C., Hunt C., Critchley J., Nguyen L., Gossler A., Göttgens B., Matter J.-M., and Guillemot F. (2006). Proneural bHLH and Brn proteins co-regulate a neurogenic programme through cooperative binding to a conserved DNA motif. Dev. Cell 11, 831-44.

Kiernan, A. E., Cordes R., Kopan R., Gossler A. and Gridley T. (2005). The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development, 132, 4353-4362.

Cordes, R., Schuster-Gossler, K., Serth, K. and Gossler, A. (2004). Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development, 131, 1221-1233.

Bussen, M., Petry, M., Schuster-Gossler, K., Leitges, M. Gossler, A. and Kispert, A. (2004). The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes & Development, 18, 1209-1221

Ben Abdelkhalek H., Beckers A., Schuster-Gossler K., Pavlova M.N., Burkhardt H., Lickert H., Rossant J., Reinhardt R., Schalkwyk L.C., Müller I., Herrmann B.G., Ceolin M., Rivera-Pomar R., and Gossler A. (2004). The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation. Genes & Development, 18, 1725-36.

Hofmann M., Schuster-Gossler K., Watabe-Rudolph M., Auhlela A., Herrman B.G. and Gossler A. (2004). WNT signaling, in synergy with T/TBX6 controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Genes & Development, 18, 2712-2717.

Aulehla A., Wehrle C., Brand-Saberi B., Kemler R., Gossler A., Kanzler B., Herrmann B. G. (2003). Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev. Cell 4(3), 395-406.

Serth, K., Schuster-Gossler, K., Cordes, R. and Gossler, A. (2003). Transcriptional oscillation of Lunatic fringe is essential for somitogenesis. Genes & Development 17, 912-925

Kispert, A. and Gossler, A. (2004). Introduction into early mouse development. In Handbook of Experimental Animals: The Laboratory Mouse (H.J. Hedrich, ed.). Academic press

Takahashi, Y., Inoue, T., Gossler, A. and Saga, Y. (2003). Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostro-caudal patterning of somites. Development, 130, 4259-4268