Publikationen der StrucMed Studierenden

PublikationenStrucMed.pdf

(Stand 06.04.11)

Erichsen TJ, Aehlen A, Ehmer U, Kalthoff S, Manns MP, Strassburg CP. Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids. J Hepatol. 2010; 52(4):570-8.

Illsinger S, Janzen N, Sander S, Schmidt KH, Bednarczyk J, Mallunat L, Bode J, Hagebölling F, Hoy L, Lücke T, Hass R, Das AM. Preeclampsia and HELLP syndrome: impaired mitochondrial function in umbilical endothelial cells. Reprod Sci. 2010 Mar;17(3):219-26.

Bürgel B, Friesland M, Koch A, Manns MP, Wedemeyer H, Weissenborn K, Schulz-Schaeffer WJ, Pietschmann T, Steinmann E, Ciesek S. Hepatitis C virus enters human peripheral neuroblastoma cells - evidence for extra-hepatic cells sustaining hepatitis C virus penetration. J Viral Hepat. 2010 Jun 23. [Epub ahead of print]

Carlens J, Wahl B, Ballmaier M, Bulfone-Paus S, Förster R, Pabst O. Common gamma-chain-dependent signals confer selective survival of eosinophils in the murine small intestine. J Immunol. 2009;183(9):5600-7.

Dey-Hazra E, Hertel B, Kirsch T, Woywodt A, Lovric S, Haller H, Haubitz M, Erdbruegger U. Detection of circulating microparticles by flow cytometry: influence of centrifugation, filtration of buffer, and freezing. Vasc Health Risk Manag. 2010 Dec 6;6:1125-33.

Duesberg CB, Welte T, Pletz MW. The Lys137Asn mutation as surrogate marker for developing fluoroquinolone resistance in Streptococcus pneumoniae? J Chemother. 2007;19(6):750-1; discussion 751-2.

Duesberg CB, Malhotra-Kumar S, Goossens H, McGee L, Klugman KP, Welte T, Pletz MW. Interspecies recombination occurs frequently in quinolone resistance determining regions of clinical isolates of Streptococcus pyogenes. Antimicrob Agents Chemother. 2008; 52(11):4191-3.

Schmidt A, Jabusch HC, Altenmüller E, Hagenah J, Brüggemann N, Lohmann K, Enders L, Kramer PL, Saunders-Pullman R, Bressman SB, Münchau A, Klein C. Etiology of musician's dystonia: familial or environmental? Neurology. 2009 Apr 7; 72(14):1248-54.

Schmidt A, Jabusch HC, Altenmüller E, Enders L, Saunders-Pullman R, Bressman SB, Münchau A, Klein C, Hagenah J. Phenotypic spectrum of musician´s dystonia: A task-specific disorder? Movement disorder 2010 (in press).

Enders L, Spector JT, Altenmüller E, Schmidt A, Klein C, Jabusch HC. Musician´s Dystonia and comorbid anxiety: two sides of one coin? Movement Disorder 2010 (in press).

Kreimeyer I, Euler F, Marckscheffel A, Tatge H, Pich A, Olling A, Schwarz J, Just I, Gerhard R. Autoproteolytic cleavage mediates cytotoxicity of Clostridium difficile toxin A. Naunyn Schmiedebergs Arch Pharmacol. 2011 Mar;383(3):253-62.

Greten TF, Ormandy LA, Fikuart A, Höchst B, Henschen S, Hörning M, Manns MP, Korangy F. Low-dose cyclophosphamide treatment impairs regulatory T cells and unmasks AFP-specific CD4+ T-cell responses in patients with advanced HCC. Journal of Immunotherapy, 2010 Feb-Mar;33(2):211-8.

Niebuhr M, Gathmann M, Scharonow H, Mamerow D, Mommert S, Balaji H, Werfel T. Staphylococcal a-toxin is a strong inducer of Interleukin (IL)-17 in humans. Infect Immun. 2011 Jan 18. [Epub ahead of print]

Niebuhr M, Scharonow H, Gathmann M, Mamerow D, Werfel T. Staphylococcal exotoxins are strong inducers of IL-22: A potential role in atopic dermatitis. J Allergy Clin Immunol. 2010; 126(6):1176-83

Hahn A, Thiessen N, Pabst R, Buettner M, Bode U. Mesenteric lymph nodes are not required for an intestinal immunoglobulin A response to oral cholera toxin. Immunology. 2010 Mar;129(3):427-36.

Halabi-Cabezon I, Huelsenbeck J, May M, Ladwein M, Rottner K, Just I, Genth H. Prevention of the cytopathic effect induced by Clostridium difficile Toxin B by active Rac1. FEBS Lett. 2008; 582(27):3751-6

Halle S, Bumann D, Herbrand H, Willer Y, Dahne S, Forster R, Pabst O. Solitary intestinal lymphoid tissue provides a productive port of entry for Salmonella enterica serovar Typhimurium. Infect Immun. 2007; 75(4):1577-85.

Herbold W, Maus R, Hahn I, Ding N, Srivastava M, Christman JW, Mack M, Reutershan J, Briles DE, Paton JC, Winter C, Welte T, Maus UA.Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudate macrophage recruitment in response to pneumococcal lung infection. Infect Immun. 2010;78(6):2620-30. Epub 2010 Apr 5

Ehlers S, Herbst C, Zimmermann M, Scharn N, et al. Granulocyte colony-stimulating factor (G-CSF) treatment of childhood acute myeloid leukemias that overexpress the differentiation-defective G-CSF receptor isoform IV is associated with a higher incidence of relapse. J Clin Oncol. 2010 May 20;28(15):2591-7.

Christgen M, Christgen H, Heil C, Krech T, Länger F, Kreipe H, Lehmann U. Expression of KAI1/CD82 in distant metastases from estrogen receptor-negative breast cancer. Cancer Sci. 2009 Sep;100(9):1767-71.

Klusmann JH, Godinho FJ, Heitmann K, Maroz A, Koch ML, Reinhardt D, Orkin SH, Li Z Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis, Genes Dev. 2010 Aug 1;24(15):1659-72

Herbold W, Maus R, Hahn I, Ding N, Srivastava M, Christman JW, Mack M, Reutershan J, Briles DE, Paton JC, Winter C, Welte T, Maus UA. Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudate macrophage recruitment in response to pneumococcal lung infection. Infect Immun. 2010 Jun;78(6):2620-30.

Winter C, Herbold W, Maus R, Länger F, Briles DE, Paton JC, Welte T, Maus UA.Important role for CC chemokine ligand 2-dependent lung mononuclear phagocyte recruitment to inhibit sepsis in mice infected with Streptococcus pneumoniae.J Immunol. 2009;182(8):4931-7

Bock O, Höftmann J, Theophile K, Hussein K, Wiese B, Schlué J, Kreipe H: Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines. Am J Pathol. 2008, 172(4): 951-960

Jakobi J, Bernateck M, Tran AT, Holm L, Volkmann L, Buers D, Karst M, Stuhrmann M. Catechol-O-methyltransferase gene polymorphisms are not associated with multisomatoform disorder in a group of German multisomatoform disorder patients and healthy controls. Genet Test Mol Biomarkers. 2010 Jun;14(3):293-7.

Jörgens G, Bange FC, Mühlradt PF, Pabst R, Maus UA, Tschernig T. Synthetic lipopeptide MALP-2 inhibits intracellular growth of Mycobacterium bovis BCG in alveolar macrophages-preliminary data. Inflammation. 2009 Aug;32(4):247-51.

Kahlmann D, Davalos-Misslitz AC, Ohl L, Stanke F, Witte T, Forster R. Genetic variants of chemokine receptor CCR7 in patients with systemic lupus erythematosus, Sjogren's syndrome and systemic sclerosis. BMC Genet. 2007;8:33.

Hong HS, Eberhard JM, Keudel P, Bollmann BA, Ahmad F, Ballmaier M, Bhatnagar N, Zielinska-Skowronek M, Schmidt RE, Meyer-Olson D. Phenotypically and functionally distinct subsets contribute to the expansion of CD56-/CD16+ natural killer cells in HIV infection. AIDS. 2010 Jul 31;24(12):1823-34.

Hong HS, Eberhard JM, Keudel P, Bollmann BA, Ballmaier M, Bhatnagar N, Zielinska-Skowronek M, Schmidt RE, Meyer-Olson D. HIV infection is associated with a preferential decline in less-differentiated CD56dim CD16+ NK cells. J Virol. 2010 Jan;84(2):1183-8.

Schade J, Stephan M, Schmiedl A, Wagner L, Niestroj AJ, Demuth HU, Frerker N, Klemann C, Raber KA, Pabst R, von Hörsten S. Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats. J Histochem Cytochem. 2008;56(2):147-55.

Klemann C, Schade J, Pabst R, Leitner S, Stiller J, von Hörsten S, Stephan M. CD26/dipeptidyl peptidase 4-deficiency alters thymic emigration patterns and leukocyte subsets in F344-rats age-dependently. Clinical and Experimental Immunology 2009; 155(2):357-65. 

Kreimeyer I, Euler F, Marckscheffel A, Tatge H, Pich A, Olling A, Schwarz J, Just I, Gerhard R. Autoproteolytic cleavage mediates cytotoxicity of Clostridium difficile toxin A. Naunyn Schmiedebergs Arch Pharmacol. 2011 Mar;383(3):253-62.

Lautenbach A, Budde A, Wrann CD, Teichmann B, Vieten G, Karl T, Nave H. Obesity and the associated mediators leptin, estrogen and IGF-I enhance the cell proliferation and early tumorigenesis of breast cancer cells. Nutr Cancer. 2009;61(4):484-91

Lautenbach A, Wrann CD, Jacobs R, Müller G, Brabant G, Nave H. Altered Phenotype of NK Cells From Obese Rats Can Be Normalized by Transfer Into Lean Animals. Obesity (Silver Spring). 2009; 17(10):1848-55.

Wrann CD, Ehmer U, Lautenbach A, Kuhlmann S, Nave H. Obesity and NK cells affect the expression of the long form of the leptin receptor Ob-Rb in liver of F344 rats. Exp Toxicol Pathol. 2010;62(1):1-8.

Luecke N, Templin C, Muetzelburg MV, Neumann D, Just I, Pich A.Secreted proteome of the murine multipotent hematopoietic progenitor cell line DKmix. Rapid Commun Mass Spectrom. 2010 Mar 15;24(5):561-70.

Broere N, Chen M, Cinar A, Singh AK, Hillesheim J, Riederer B, Lünnemann M, Rottinghaus I, Krabbenhöft A, Engelhardt R, Rausch B, Weinman EJ, Donowitz M, Hubbard A, Kocher O, de Jonge HR, Hogema BM, Seidler U. Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice. Pflugers Arch. 2009 Mar;457(5):1079-91.

Illsinger S, Janzen N, Sander S, Schmidt KH, Bednarczyk J, Mallunat L, Bode J, Hagebölling F, Hoy L, Lücke T, Hass R, Das AM. Preeclampsia and HELLP syndrome: impaired mitochondrial function in umbilical endothelial cells. Reprod Sci. 2010 Mar;17(3):219-26.

Satzger I, Mattern A, Kuettler U, Weinspach D, Voelker B, Kapp A, Gutzmer R. MicroRNA-15b represents an independent prognostic parameter and is correlated with tumor cell proliferation and apoptosis in malignant melanoma. Int J Cancer. 2010;126(11):2553-62.

Omnus DJ, Mehrtens S, Ritter B, Resch K, Yamada M, Frank R, Nourbakhsh M, Reboll MR. JKTBP1 Is Involved in Stabilization and IRES-Dependent Translation of NRF mRNAs by Binding to 5' and 3' Untranslated Regions. J Mol Biol. 2011 Feb 12. [Epub ahead of print] PubMed PMID: 21300069.

Srivastava M, Meinders A, Steinwede K, Maus R, Lucke N, Buhling F, Ehlers S, Welte T, Maus UA. Mediator responses of alveolar macrophages and kinetics of mononuclear phagocyte subset recruitment during acute primary and secondary mycobacterial infections in the lungs of mice. Cell Microbiol. 2007; 9(3):738-52.

Meyer D, Seth S, Albrecht J, Maier MK, du Pasquier L, Ravens I, Dreyer L, Burger R, Gramatzki M, Schwinzer R, Kremmer E, Foerster R, Bernhardt G. CD96 interaction with CD155 via its first Ig-like domain is modulated by alternative splicing or mutations in distal Ig-like domains. J Biol Chem. 2009 Jan 23;284(4):2235-44.

Muhr P, Renne J, Schaefer V, Werfel T, Wittmann M. Primary human keratinocytes efficiently induce IL-1-dependent IL-17 in CCR6+ T cells. Exp Dermatol. 2010 Dec;19(12):1105-7.

Muller-Deile J, Brocker V, Grunwald V, Hiss M, Bertram A, Kubicka S, Ganser A, Haller H, Schiffer M: Renal side effects of VEGF-blocking therapy. NDT Plus 2009

Muller-Deile J, Worthmann K, Saleem M, Tossidou I, Haller H, Schiffer M: The balance of autocrine VEGF-A and VEGF-C determines podocyte survival. Am J Physiol Renal Physiol 2009; 297: F1656-1667

Müller S, Poehnert D., Müller J.A., Scheumann G.W.F., Koch M, Lück R.. Regulatory T-cells in peripheral blood, lymph node and thyroid tissue in patients with medullar thyroid carcinoma. World Journal of Surgery, in press

Negm AA, Schott A, Vonberg RP, Weismueller TJ, Schneider AS, Kubicka S, Strassburg CP, Manns MP, Suerbaum S, Wedemeyer J, Lankisch TO. Routine bile collection for microbiological analysis during cholangiography and its impact on the management of cholangitis. Gastrointest Endosc. 2010 Aug;72(2):284-91.

Lankisch TO, Metzger J, Negm AA, Voβkuhl K, Schiffer E, Siwy J, Weismüller TJ, Schneider AS, Thedieck K, Baumeister R, Zürbig P, Weissinger EM, Manns MP, Mischak H, Wedemeyer J. Bile proteomic profiles differentiate cholangiocarcinoma from primary sclerosing cholangitis and choledocholithiasis. Hepatology. 2010 Dec 7. [Epub ahead of print]

Weismüller TJ, Negm AA, Bcker T, Barg-Hock H, Klempnauer J, Manns MP, Strassburg CP. The introduction of MELD-based organ allocation impacts 3-month survival after liver transplantation by influencing pretransplant patient characteristics. Transpl Int. 2009 Oct;22(10):970-8. Epub 2009 Jul 10.

Lorenzen JM, Nickel N, Krämer R, Golpon H, Westerkamp V, Olsson KM, Haller H, Hoeper MM. Osteopontin in patients with idiopathic pulmonary hypertension. Chest. 2010 Oct 14.

Kümpers P, Nickel N, Lukasz A, Golpon H, Westerkamp V, Olsson KM, Jonigk D, Maegel L, Bockmeyer CL, David S, Hoeper MM. Circulating angiopoietins in idiopathic pulmonary arterial hypertension. Eur Heart J. 2010 Sep;31(18):2291-300.

Hoeper MM, Gall H, Seyfarth HJ, Halank M, Ghofrani HA, Winkler J, Golpon H, Olsson KM, Nickel N, Opitz C, Ewert R. Long-term outcome with intravenous iloprost in pulmonary arterial hypertension. Eur Respir J. 2009 Jul;34(1):132-7.

Nickel N, Kempf T, Tapken H, Tongers J, Laenger F, Lehmann U, Golpon H, Olsson K, Wilkins MR, Gibbs JS, Hoeper MM, Wollert KC. Growth differentiation factor-15 in idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med. 2008 Sep 1;178(5):534-41.

Zudem wurde diese Arbeit mit dem "pulmonary aterial hypertension award 2008" auf dem ERS (european respiratory society) ausgezeichnet.

Nottrott S, Schoentaube J, Genth H, Just I, Gerhard R. Clostridium difficile toxin A-induced apoptosis is p53-independent but depends on glucosylation of Rho GTPases. Apoptosis 2007; 12(8):1443-53

Gerhard R, Nottrott S, Schoentaube J, Tatge H, Olling A, Just I. Glucosylation of Rho GTPases by Clostridium difficile toxin A triggers apoptosis in intestinal epithelial cells. J Med Microbiol. 2008; 57(Pt 6):765-70

Peest U, Sensken SC, Andréani P, Hänel P, Van Veldhoven PP, Gräler MH. S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake. J Cell Biochem.2008 Jun 1;104(3):756-7

Bode C, Sensken SC, Peest U, Beutel G, Thol F, Levkau B, Li Z, Bittman R, Huang T, Tölle M, van der Giet M, Gräler MH. Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphate. J Cell Biochem. 2010;109(6):1232-43.

Sensken SC, Bode C, Nagarajan M, Peest U, Pabst O, Gräler MH. Redistribution of sphingosine 1-phosphate by sphingosine kinase 2 contributes to lymphopenia. J Immunol. 2010;184(8):4133-42.

Salguero G, Schuett H, Jagielska J, Schley R, Tallone E, Luchtefeld M, Drexler H, Müller W, Grote K, Schieffer B. Hepatocyte gp130 Deficiency Reduces Vascular Remodeling After Carotid Artery Ligation. Hypertension. 2009 Nov;54(5):1035-42.

Schreiber O, Steinwede K, Ding N, Srivastava M, Maus R, Länger F, Prokein J, Ehlers S, Welte T, Gunn MD, Maus UA. Mice that overexpress CC chemokine ligand 2 in their lungs show increased protective immunity to infection with Mycobacterium bovis bacille Calmette-Guérin. J Infect Dis. 2008;198(7):1044-54.

Tossidou I*, Starker G*, Kruger J, Meier M, Leitges M, Haller H, Schiffer M. PKC-alpha modulates TGF-beta signaling and impairs podocyte survival. Cell Physiol Biochem. 2009; 24(5-6):627-34. (joint authorship)

Winter C, Taut K, Länger F, Mack M, Briles DE, Paton JC, Maus R, Srivastava M, Welte T, Maus UA. FMS-like tyrosine kinase 3 ligand aggravates the lung inflammatory response to Streptococcus pneumoniae infection in mice: role of dendritic cells. J Immunol. 2007;179(5):3099-108

Taut K, Winter C, Briles DE, Paton JC, Christman JW, Maus R, Baumann R, Welte T, Maus UA. Macrophage Turnover Kinetics in the Lungs of Mice Infected with Streptococcus pneumoniae. Am J Respir Cell Mol Biol. 2008;38(1):105-13. Epub 2007 Aug 9.

Winter C, Taut K, Srivastava M, Länger F, Mack M, Briles DE, Paton JC, Maus R, Welte T, Gunn MD, Maus UA. Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis. J Immunol. 2007;178(9):5828-38.

Hahn A, Thiessen N, Pabst R, Buettner M, Bode U. Mesenteric lymph nodes are not required for an intestinal immunoglobulin A response to oral cholera toxin. Immunology. 2010 Mar;129(3):427-36.

Thöne F, Schwanhäusser B, Becker D, Ballmaier M, Bumann D. FACS-isolation of Salmonella-infected cells with defined bacterial load from mouse spleen. J Microbiol Methods. 2007;71(3):220-4.

Kielstein JT, Fliser D, Veldink H. Asymmetric dimethylarginine and symmetric dimethylarginine: axis of evil or useful alliance?. Semin Dial 2009; 22: 346-3502.

Lorenzen J, Krämer R, Kliem V, Bode-Boeger SM, Veldink H, Haller H, Fliser D, Kielstein JT. Circulating levels of osteopontin are closely related to glomerular filtration rate and cardiovascular risk markers in patients with chronic kidney disease.. Eur J Clin Invest 2010; 40 (4): 294–300.

Veldink H; Kielstein JT; Martens-Lobenhoffer J; Haller H; Burg M; Lorenzen JM; Lichtinghagen R; Bode-Böger SM; Kliem V. SDMA is an early marker of change in GFR after living-related kidney donation. Nephrology Dialysis Transplantation 2010; doi: 10.1093/ndt/gfq395

Veldink H, Kielstein JT, Martens-Lobenhoffer J, Haller H, Perthel R, Lovric S, Lichtinghagen R, Kliem V, Bode-Böger SM. Unilateral nephrectomy causes an abrupt increase an inflammatory mediators and a simultaneous decrease in plasma ADMA - a study in living kidney donors. Am J Physiol Renal Physiol. 2011 Aug 10.

Winkler C, Hüper K, Wedekind AC, Rochlitzer S, Hartwig C, Müller M, Braun A, Krug N, Hohlfeld JM, Erpenbeck VJ. Surfactant protein D modulates pulmonary clearance of pollen starch granules. Exp Lung Res. 2010 Nov;36(9):522-30.

In Vorbereitung/ under review:
Elisabeth Schock
Alexandra Knoll
Julia Höftmann
Jörg Langemeier
Judith Penkert