Publikationen

2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008

Bertram C, von Neuhoff N, Skawran B, Steinemann D, Schlegelberger B, Hass R. The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97. BMC Cell Biol 2008;9:12. [PubMed]

Buesche G, Teoman H, Wilczak W, Ganser A, Hecker H, Wilkens L, Gohring G, Schlegelberger B, Bock O, Georgii A, Kreipe H. Marrow fibrosis predicts early fatal marrow failure in patients with myelodysplastic syndromes. Leukemia 2008;22:313-322. [PubMed]

Chao MM, Kontny U, Brink I, Gohring G, Schmitt-Graff A, Rister M, Strahm B. Extramedullary relapse of therapy-related myelodysplastic syndrome after donor leukocyte infusion. Ann Hematol 2008;87:165-166. [PubMed]

Hertz S, Rothamel T, Skawran B, Giere C, Steinemann D, Flemming P, Becker T, Flik J, Wiese B, Soudah B, Kreipe H, Schlegelberger B, Wilkens L. Losses of chromosome arms 4q, 8p, 13q and gain of 8q are correlated with increasing chromosomal instability in hepatocellular carcinoma. Pathobiology 2008;75:312-322. [PubMed]

Kiechle M, Arnold N, Schlegelberger B. Hereditäres Ovarialkarzinom. Onkologe 2008;14:1120-1129.

Kumpers P, Koenecke C, Hecker H, Hellpap J, Horn R, Verhagen W, Buchholz S, Hertenstein B, Krauter J, Eder M, David S, Gohring G, Haller H, Ganser A. Angiopoietin-2 predicts disease-free survival after allogeneic stem cell transplantation in patients with high-risk myeloid malignancies. Blood 2008;112:2139-2148. [PubMed]

Lauten M, Fernandez-Munoz I, Gerdes K, von Neuhoff N, Welte K, Schlegelberger B, Schrappe M, Beger C. Kinetics of the in vivo expression of glucocorticoid receptor splice variants during prednisone treatment in childhood acute lymphoblastic leukaemia. Pediatr Blood Cancer 2008; Dec 5 [E-pub ahead of print] [PubMed]

Lehmann U, Dobbelstein C, Fenner M, Romermann D, Hasemeier B, Metzig K, Steinemann D, Busche G, Krauter J, Ganser A, Kreipe H. Complete cytogenetic remission after decitabine treatment in a patient with secondary AML harbouring high p15 ( INK4b ) gene methylation and high global DNA methylation. Ann Hematol 2008; Aug 13 [E-pub ahead of print] [PubMed]

Li Z, Beutel G, Rhein M, Meyer J, Koenecke C, Neumann T, Yang M, Krauter J, von Neuhoff N, Heuser M, Diedrich H, Gohring G, Wilkens L, Schlegelberger B, Ganser A, Baum C. High affinity neurotrophin receptors and ligands promote leukemogenesis. Blood 2008; Dec 4 [E-pub ahead of print] [PubMed]

Modlich U, Schambach A, Brugman MH, Wicke DC, Knoess S, Li Z, Maetzig T, Rudolph C, Schlegelberger B, Baum C. Leukemia induction after a single retroviral vector insertion in Evi1 or Prdm16. Leukemia 2008;22:1519-1528. [PubMed]

Osorio A, Pollan M, Pita G, Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Preisler-Adams S, Niederacher D, Hofmann W, Gadzicki D, Jakubowska A, Hamann U, Lubinski J, Toloczko-Grabarek A, Cybulski C, Debniak T, Llort G, Yannoukakos D, Diez O, Peissel B, Peterlongo P, Radice P, Heikkinen T, Nevanlinna H, Mai PL, Loud JT, McGuffog L, Antoniou AC, Benitez J. An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriers. Br J Cancer 2008;99:974-977. [PubMed]

Ripperger T, Gadzicki D, Meindl A, Schlegelberger B. Breast cancer susceptibility: current knowledge and implications for genetic counselling. Eur J Hum Genet 2008; Dec 17 [E-pub ahead of print] [PubMed]

Römermann D, Hasemeier B, Metzig K, Göhring G, Schlegelberger B, Länger F, Kreipe H, Lehmann U. Global increase in DNA methylation in patients with myelodysplastic syndrome. Leukemia 2008;22:1954-1956. [PubMed]

Sarlette A, Krampfl K, Grothe C, Neuhoff N, Dengler R, Petri S. Nuclear erythroid 2-related factor 2-antioxidative response element signaling pathway in motor cortex and spinal cord in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2008;67:1055-1062. [PubMed]

Schlenk RF, Dohner K, Krauter J, Frohling S, Corbacioglu A, Bullinger L, Habdank M, Spath D, Morgan M, Benner A, Schlegelberger B, Heil G, Ganser A, Dohner H. Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Engl J Med 2008;358:1909-1918. [PubMed]

Schubert S, Kamino K, Bohm D, Adham I, Engel W, von Wasielewski R, Moharregh-Khiabani D, Mauceri G, Vaske B, Meinhardt A, Schoner A, Gonzalez-Fassrainer D, Schmidtke J. TSPY expression is variably altered in transgenic mice with testicular feminization. Biol Reprod 2008;79:125-133. [PubMed]

Skawran B, Steinemann D, Becker T, Buurman R, Flik J, Wiese B, Flemming P, Kreipe H, Schlegelberger B, Wilkens L. Loss of 13q is associated with genes involved in cell cycle and proliferation in dedifferentiated hepatocellular carcinoma. Mod Pathol 2008;21:1479-1489. [PubMed]

Skawran B, Steinemann D, Weigmann A, Flemming P, Becker T, Flik J, Kreipe H, Schlegelberger B, Wilkens L. Gene expression profiling in hepatocellular carcinoma: upregulation of genes in amplified chromosome regions. Mod Pathol 2008;21:505-516. [PubMed]

Staboulidou I, Miller K, Göhring G, Hillemanns P, Wüstemann M. Prenatal diagnosis of an epignathus associated with a 49,XXXXY karyotype--a case report. Fetal Diagn Ther 2008;24:313-317. [PubMed]

Steinemann D, Cario G, Stanulla M, Karawajew L, Tauscher M, Weigmann A, Gohring G, Ludwig WD, Harbott J, Radlwimmer B, Bartram C, Lichter P, Schrappe M, Schlegelberger B. Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease. Genes Chromosomes Cancer 2008;47:471-480. [PubMed]

Templin C, Kotlarz D, Rathinam C, Rudolph C, Schätzlein S, Ramireddy K, Rudolph KL, Schlegelberger B, Klein C, Drexler H. Establishment of immortalized multipotent hematopoietic progenitor cell lines by retroviral-mediated gene transfer of beta-catenin. Exp Hematol 2008;36:204-215. [PubMed]

Werwitzke S, Trick D, Sondermann P, Kamino K, Schlegelberger B, Kniesch K, Tiede A, Jacob U, Schmidt RE, Witte T. Treatment of lupus-prone NZB/NZW F1 mice with recombinant soluble Fc gamma receptor II (CD32). Ann Rheum Dis 2008;67:154-161. [PubMed]

Buchbeiträge

Gadzicki D, Schlegelberger B. Genetic counseling for hereditary tumors. In: Allgayer H, Rehder H, Fulda S. [eds.]: Hereditary Tumors. From Genes to Clinical Consequences. Wiley-VCH, Weinheim, 2008. pp. 469-485.

Göhring G, Schlegelberger B, Hellström-Lindberg E. Chapter 9: Myelodysplastic syndromes. In: Stilgenbauer S, Döhner H. [eds.]:Molecular Diagnostics in Hematological Oncology. UNI-MED, Bremen, 2008. pp. 117-125.

Schlegelberger B, Göhring G. Zytogenetische Diagnostik bei Leukämien und malignen Lymphomen. In: Bruhn HD, Fölsch UR, Schäfer H [Hrsg.]: LaborMedizin. Indikationen, Methodik und Laborwerte. Pathophysiologie und Klinik. 2. Auflage. Schattauer, Stuttgart, 2008. S. 446-452.

Buesche G, Ganser A, Schlegelberger B, von Neuhoff N, Gadzicki D, Hecker H, Bock O, Frye B, Kreipe H. Marrow fibrosis and its relevance during imatinib treatment of chronic myeloid leukemia. Leukemia 2007;21:2420-7. [PubMed]

Cario G, Izraeli S, Teichert A, Rhein P, Skokowa J, Moricke A, Zimmermann M, Schrauder A, Karawajew L, Ludwig WD, Welte K, Schunemann HJ, Schlegelberger B, Schrappe M, Stanulla M. High interleukin-15 expression characterizes childhood acute lymphoblastic leukemia with involvement of the CNS. J Clin Oncol 2007;25:4813-20. [PubMed]

Flotho C, Steinemann D, Mullighan CG, Neale G, Mayer K, Kratz CP, Schlegelberger B, Downing JR, Niemeyer CM. Genome-wide single-nucleotide polymorphism analysis in juvenile myelomonocytic leukemia identifies uniparental disomy surrounding the NF1 locus in cases associated with neurofibromatosis but not in cases with mutant RAS or PTPN11. Oncogene 2007;26:5816-21. [PubMed]

Gerhardus A, Schleberger H, Schlegelberger B, Gadzicki D. Diagnostic accuracy of methods for the detection of BRCA1 and BRCA2 mutations: a systematic review. Eur J Hum Genet 2007;15:619-27. [PubMed]

Neises M, Gadzicki D. Erblicher Brust/Ovarialkrebs - Genetische Diagnostik und psychosomatische Aspekte. Psychosom. Konsillarpsychiatr. 2007;73:287-92. German

Gerr HD, Nassin ML, Davis EM, Jayathilaka N, Neilly ME, Schlegelberger B, Zhang Y, Rowley JD. Cytogenetic and molecular study of the PRDX4 gene in a t(X;18) (p22;q23): a cautionary tale. Cancer Genet Cytogenet 2007;176:131-6. [PubMed]

Giagounidis AA, Haase S, Heinsch M, Göhring G, Schlegelberger B, Aul C. Lenalidomide in the context of complex karyotype or interrupted treatment: case reviews of del(5q)MDS patients with unexpected responses. Ann Hematol 2007;86:133-7. [PubMed]

Göhring G, Erlacher M, van Buiren M, Jüttner E, Niemeyer C, Schlegelberger B. Mesenteric chloroma with t(16;16) followed by acute myelomonocytic leukemia with clonal evolution. Cancer Genet Cytogenet 2007;179:162-4. [PubMed]

Göhring G, Karow A, Steinemann D, Wilkens L, Lichter P, Zeidler C, Niemeyer C, Welte K, Schlegelberger B. Chromosomal aberrations in congenital bone marrow failure disorders – an early indicator for leukemogenesis? Ann Hematol 2007;86:733-9. [PubMed]

Göhring G, Lange K, Atta J, Krauter J, Hölzer D, Schlegelberger B. Cryptic translocation t(15;17) in a patient with AML M3 and a complex karyotype. Cancer Genet Cytogenet 2007;175:77-80. [PubMed]

Heuser M, Argiropoulos B, Kuchenbauer F, Yung E, Piper J, Fung S, Schlenk RF, Döhner K, Hinrichsen T, Rudolph C, Schambach A, Baum C, Schlegelberger B, Döhner H, Ganser A, Humphries RK. MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML. Blood 2007;110:1639-47. [PubMed]

Hussein K, Bock O, Ballmaier M, Göhring G, Steinemann D, Lehmann U, Kemper J, Buhr T, Kreipe H. Familial polycythemia vera with non-germline JAK2(V617F) mutation sparing the abnormal and clonal granulopoiesis. Leukemia 2007;21:2566-8. [PubMed]

Ji P, Bäumer N, Yin T, Diederichs S, Zhang F, Beger C, Welte K, Fulda S, Berdel WE, Serve H, Müller-Tidow C. DNA damage response involves modulation of Ku70 and Rb functions by cyclin A1 in leukemia cells. Int J Cancer 2007;121:706-13. [PubMed]

Karow A, Steinemann D, Göhring G, Hasle H, Greiner J, Harila-Saari A, Flotho C, Zenker M, Schlegelberger B, Niemeyer CM, Kratz CP. Clonal duplication of a germline PTPN11 mutation due to acquired uniparental disomy in acute lymphoblastic leukemia blasts from a patient with Noonan syndrome. Leukemia 2007;21:1303-5. [PubMed]

Korf M, Meyer A, Jarczak D, Beger C, Manns MP, Krüger M. Inhibition of HCV subgenomic replicons by siRNAs derived from plasmids with opposing U6 and H1 promoters. J Viral Hepat 2007;14:122-32. [PubMed]

Kratz CP, Steinemann D, Niemeyer CM, Schlegelberger B, Koscielniak E, Kontny U, Zenker M. Uniparental disomy at chromosome 11p15.5 followed by HRAS mutations in embryonal rhabdomyosarcoma: lessons from Costello syndrome. Hum Mol Genet 2007;16:374-9. [PubMed]

Lechel A, Holstege H, Begus Y, Schienke A, Kamino K, Lehmann U, Kubicka S, Schirmacher P, Jonkers J, Rudolph KL. Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease. Gastroenterology 2007;132:1465-75. [PubMed]

Li Z, Kustikova OS, Kamino K, Neumann T, Rhein M, Grassman E, Fehse B, Baum C. Insertional mutagenesis by replication-deficient retroviral vectors encoding the large T oncogene. Ann N Y Acad Sci 2007;1106:95-113. [PubMed]

Meyer J, Rhein M, Schiedlmeier B, Kustikova O, Rudolph C, Kamino K, Neumann T, Yang M, Wahlers A, Fehse B, Reuther GW, Schlegelberger B, Ganser A, Baum C, Li Z. Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, deltaTrkA. Leukemia 2007;21:2171-80. [PubMed]

Pagenstecher C, Gadzicki D, Stienen D, Uhlhaas S, Mangold E, Rahner N, Arslan-Kirchner M, Propping P, Friedl W, Aretz S. A complex rearrangement in the APC gene uncovered by multiplex ligation-dependent probe amplification. J Mol Diagn 2007;9:122-6. [PubMed]

Plentz RR, Park YN, Lechel A, Kim H, Nellessen F, Langkopf BH, Wilkens L, Destro A, Fiamengo B, Manns MP, Roncalli M, Rudolph KL. Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis. Hepatology 2007;45:968-76. [PubMed]

Reimann M, Loddenkemper C, Rudolph C,  Schildhauer I, Teichmann B, Stein H, Schlegelberger B, Dorken B, Schmitt CA. The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo. Blood 2007;110:2996-3004. [PubMed]

Ripperger T, von Neuhoff N, Kamphues K, Emura M, Lehmann U, Tauscher M, Schraders M, Groenen P, Skawran B, Rudolph C, Callet-Bauchu E, van Krieken JH, Schlegelberger B, Steinemann D. Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle cell lymphomas. Haematologica 2007;92:460-468. [PubMed]

Schaetzlein S, Kodandaramireddy NR, Ju Z, Lechel A, Stepczynska A, Lilli DR, Clark AB, Rudolph C, Wei K, Schlegelberger B, Schirmacher P, Kunkel TA, Greenberg RA, Edelmann W, Rudolph KL. Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice. Cell 2007;130:863-77. [PubMed]

Will E, Bailey J, Schuesler T, Modlich U, Balcik B, Burzynski B, Witte D, Layh-Schmitt G, Rudolph C, Schlegelberger B, von Kalle C, Baum C, Sorrentino BP, Wagner LM, Kelly P, Reeves L, Williams DA. Importance of murine study design for testing toxicity of retroviral vectors in support of phase I trials. Mol Ther 2007;15:782-91. [PubMed]

Balakrishnan A, von Neuhoff N, Rudolph C, Kamphues K, Schraders M, Groenen P, van Krieken JM, Callet-Bauchu E, Schlegelberger B, Steinemann D. Quantitative microsatellite analysis to delineate the commonly deleted region 1p22.3 in mantle cell lymphomas. Genes Chromosomes Cancer 2006; 45:883-92. [PubMed]

Burkhardt B, Bruch J, Zimmermann M, Strauch K, Parwaresch R, Ludwig WD, Harder L, Schlegelberger B, Mueller F, Harbott J, Reiter A. Loss of heterozygosity on chromosome 6q14-q24 is associated with poor outcome in children and adolescents with T-cell lymphoblastic lymphoma. Leukemia 2006;20:1422-9. [PubMed]

Dammann CEL, Meyer M, Dammann O, von Neuhoff N. Protein detection in dried blood by surface-enhanced laser desorption/ionization-time of flight mass spectrometry (SELDI-TOF MS). Biol Neonate 2006;89:126-32. [PubMed]

de Buhr MF, Mahler M, Geffers R, Hansen W, Westendorf AM, Lauber J, Buer J, Schlegelberger B, Hedrich HJ, Bleich A. Cd14, Gbp1, and Pla2g2a: three major candidate genes for experimental IBD identified by combining QTL and microarray analyses. Physiol Genomics 2006;25:426-34. [PubMed]

El-Harith el-HA, Kuhnau W, Schmidtke J, Gadzicki D, Ahmed M, Krawczak M, Stuhrmann M. Hereditary hemorrhagic telangiectasia is caused by the Q490X mutation of the ACVRL1 gene in a large Arab family: support of homozygous lethality. Eur J Med Genet 2006;49:323-30. [PubMed]

Gerr H, Gadzicki D, Kreipe H, Schlegelberger B, Wilkens L. Floureszenz in situ hybridization reveals closly correlated results in cytological and histological specimens of hematological neoplesias compared to conventional cytogenetics. Pathobiology 2006;73:271-9. [PubMed]

Flemming P, Lehmann U, Steinemann D, Kreipe H, Wilkens L. [Hepatocellular adenoma. Malignancy potential and differentiation from hepatocellular carcinoma.] Pathologe 2006;27:238-43. [PubMed]

Gadzicki D, Baumer A, Wey E, Happel CM, Rudolph C, Tönnies H, Neitzel H, Steinemann D, Welte K, Klein C, Schlegelberger B. Jacobsen syndrome and Beckwith-Wiedemann syndrome caused by a parental pericentric inversion inv(11)(p15q24). Ann Hum Genet 2006;70:1-7. [PubMed]

Gadzicki D, Wingen LU, Teige B, Horn D, Bosse K, Kreuz F, Goecke T, Schäfer D, Voigtländer R, Fischer B, Froster U, Welling B, Debatin I, Weber BH, Schönbuchner I, Nippert I, Schlegelberger B. (for the German Cancer Aid Consortium on Hereditary Breast Cancer). Communicating BRCA1 and BRCA2 genetic test results. J Clin Oncol 2006;24:2969-70. [PubMed]

Göhring G, Hanke C, Kratz C, Kontny U, Steinemann D, Niemeyer CM, Schlegelberger B. Fluorescence in situ hybridization using the subtelomeric 11q probe as a diagnostic tool for congenital thrombocytopenia. Ann Hematol 2006;85:883-5. [PubMed]

Heuser M, Beutel G, Krauter J, Döhner K, von Neuhoff N, Schlegelberger B, Ganser A. High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics. Blood 2006;108:3898-905. [PubMed]

Hussein K, Brakensiek K, Ballmaier M, Bormann M, Göhring G, Buhr T, Bock O, Kreipe H. B-CLL developing in a patient with PV is not affected by V617F mutation of the Janus kinase 2. Eur J Haematol 2006;77:539-541. [PubMed]

Jung J, Bohn G, Allroth A, Boztug K, Brandes G, Sandrock I, Schaffer AA, Rathinam C, Kollner I, Beger C, Schilke R, Welte K, Grimbacher B, Klein C. Identification of a homozygous deletion in the AP3B1 gene causing Hermansky-Pudlak syndrome, type 2. Blood 2006;108:362-9. [PubMed]

Köllner I, Sodeik B, Schreek S, Heyn H, von Neuhoff N, Germeshausen M, Zeidler C, Kruger M, Schlegelberger B, Welte K, Beger C. Mutations in neutrophil elastase causing congenital neutropenia lead to cytoplasmic protein accumulation and induction of the unfolded protein response. Blood 2006;108:493-500. [PubMed]

Lauten M, Schrauder A, Kardinal C, Harbott J, Welte K, Schlegelberger B, Schrappe M, von Neuhoff N. Unsupervised proteome analysis of human leukaemia cells identifies the Valosin-containing protein as a putative marker for glucocorticoid resistance. Leukemia 2006;20:820-6. [PubMed]

Lucke T, Pfister S, Beger C, Durken M. Homozygous alpha-thalassaemia: Prenatal diagnosis, risks, options and counselling. Acta Paediatr 2006;95:1018.

Milde S, Gaedcke J, v Wasielewski RV, Bruchardt H, Wingen L, Gadzicki D, Arps H, Kreipe HH. [Diagnosis and immunophenotype of medullary breast cancer.] Pathologe 2006;27:358-362. [PubMed]

Loibl S, von Minckwitz G, Gwyn K, Ellis P, Blohmer JU, Schlegelberger B, Keller M, Harder S, Theriault RL, Crivellari D, Klingebiel T, Louwen F, Kaufmann M. Breast carcinoma during pregnancy. International recommendations from an expert meeting. Cancer 2006;106:237-46. [PubMed]

Park B-J, Oh YS, Park SY, Choi SJ, Rudolph C, Schlegelberger B, Kim S. AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability. Cancer Res 2006;66:6913-8. [PubMed]

Rathinam C, Sauer M, Ghosh A, Rudolph C, Hegazy A, Schlegelberger B, Welte K, Klein C. Generation and characterization of a novel hematopoietic progenitor cell line with DC differentiation potential. Leukemia 2006;20:870-6. [PubMed]

Rudolph C, Bittner C, Feller  AC, Merz H, Schlegelberger  B. Cytogenetic characteristics of a murine in vitro model for the human anaplastic large cell lymphoma (ALCL). Cytogenet Genome Res 2006;114:292-5. [PubMed]

Rudolph C, Liehr T, Steinemann D, Emura M, Daibata M, Matsuo Y, Emi N, Abe M, Lai R, Mrasek K, Claussen U, Schlegelberger B. Different breakage-prone regions on chromosome 1 detected in t(11;14)-positive mantle cell lymphoma cell lines and multiple myeloma cell lines are associated with different tumor progression-related mechanisms. Cytogenet Genome Res 2006;112:213-21. [PubMed]

Schambach A, Schiedlmeier B, Kuhlcke K, Verstegen M, Margison GP, Li Z, Kamino K, Bohne J, Alexandrov A, Hermann FG, von Laer D, Baum C. Towards hematopoietic stem cell-mediated protection against infection with human immunodeficiency virus. Gene Ther 2006;13:1037-47. [PubMed]

Staal FJ, Cario G, Cazzaniga G, Haferlach T, Heuser M, Hofmann WK, Mills K, Schrappe M, Stanulla M, Wingen LU, van Dongen JJ, Schlegelberger B. Consensus guidelines for microarray gene expression analyses in leukemia from three European leukemia networks. Leukemia 2006;20:1385-92. [PubMed]

Steinemann D, Skawran B, Becker T, Tauscher M, Weigmann A, Wingen L, Tauscher S, Hinrichsen T, Hertz S, Flemming P, Flik J, Wiese B, Kreipe H, Lichter P, Schlegelberger B, Wilkens L. Assessment of differentiation and progression of hepatic tumors using array-based comparative genomic hybridization. Clin Gastroenterol Hepatol 2006;4:1283-91. [PubMed]

Timmerbeul I, Garrett-Engele CM, Kossatz U, Chen X, Firpo E, Grunwald V, Kamino K, Wilkens L, Lehmann U, Buer J, Geffers R, Kubicka S, Manns MP, Porter PL, Roberts JM, Malek NP. Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer. Proc Natl Acad Sci U S A 2006;103:14009-14. [PubMed]

Traub F, Sickmann K, Tessema M, Wilkens L, Kreipe HH, Kamino K. Nephroblastomatosis and loss of WT1 expression associated with trisomy 13. Virchows Arch 2006;448:214-7. [PubMed]

Wilkens L, Becker T, Schlegelberger B, Kreipe HH, Flemming P. Preserved reticulin network in a case of hepatocellular carcinoma. Histopathology 2006;48:876-8. [PubMed]

Beutel G, Meyer J, Ma L, Yin S, Eder M, von Neuhoff N, Wilkens L, Wei J, Hertenstein B, Heil G, Schlegelberger B, Ganser A, Li Z, Baum C. Expression of the p75 neurotrophin receptor in acute leukaemia. Br J Haematol 2005;131:67-70. [PubMed]

Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, Schlegelberger B, Stein H, Dörken B, Jenuwein T, Schmitt CA. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 2005;436:660-5. [PubMed]

Brakensiek K, Länger F, Schlegelberger B, Kreipe H, Lehmann U. Hypermethylation of the suppressor of cytokine signalling-1 (SOCS-1) in myelodysplastic syndrome. Br J Haematol 2005;130:209-17. [PubMed]

Cario G, Stanulla M, Fine BM, Teuffel O, von Neuhoff N, Schrauder A, Flohr T, Schafer BW, Bartram CR, Welte K, Schlegelberger B, Schrappe M. Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia. Blood 2005;105(2):821-6. [PubMed]

Dammann CE, Meyer M, Dammann O, von Neuhoff N. Protein detection in dried blood by surface-enhanced laser desorption/ionization-time of flight mass spectrometry (SELDI-TOF-MS). Biol Neonate 2005;89:126-132. [PubMed]

Dengler R, von Neuhoff N, Bufler J, Krampfl K, Peschel T, Grosskreutz J. Amyotrophic lateral sclerosis: new developments in diagnostic markers. Neurodegenerative Dis 2005;2:177-184. [PubMed]

Emura M. Evidence of a single type of epithelial stem cell in the airway and its implication for the future therapeutic strategy. Pneumologie 2005;59:19.

Gadzicki D, von Neuhoff N, Steinemann D, Just M, Büsche G, Kreipe H, Wilkens L, Schlegelberger B. BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib. Cancer Genet Cytogenet 2005;159:164-7. [PubMed]

Germeshausen M, Schulze H, Kratz C, Wilkens L, Repp R, Shannon K, Welte K, Ballmaier M. An acquired G-CSF receptor gene mutation leads to expression of a truncated G-CSF receptor and confers a proliferative and anti-apoptotic signal in leukemic cells of CMML secondary to severe congenital neutropenia. Leukemia 2005;19:611-7. [PubMed]

Giagounidis AA, Haase S, Germing U, Schlegelberger B, Wilkens L, Büsche G, Kreipe HH, Wysk J, Grips KH, Grabenhorst U, Rothmann F, Lübbert M, Ganser A, Aivado M, Heinsch M, Aul C. Treatment of myelodysplastic syndrome with isolated del(5q) including bands q31-q33 with a combination of all-trans-retinoic acid and tocopherol-alpha: a phase II study. Ann Hematol 2005;84:389-94. [PubMed]

Heuser M, Wingen LU, Steinemann D, Cario G, von Neuhoff N, Tauscher M, Bullinger L, Krauter J, Heil G, Döhner H, Schlegelberger B, Ganser A. Gene-expression profiles and their association with drug resistance in adult acute myeloid leukemia. Haematologica 2005;90:1484-92. [PubMed]

Jarczak D, Korf M, Beger C, Manns MP, Krüger M. Hairpin ribozymes in combination with siRNAs against highly conserved hepatitis C virus sequences inhibit RNA replication and protein translation from hepatitis C virus subgenomic replicons. FEBS J 2005;272:5910-5922. [PubMed]

Ji P, Agrawal S, Diederichs S, Baumer N, Becker A, Cauvet T, Kowski S, Beger C, Welte K, Berdel WE, Serve H, and Müller-Tidow C. Cyclin A1, the alternative A-type cyclin, contributes to G1/S cell cycle progression in somatic cells. Oncogene 2005;24:2739-2744. [PubMed]

Korf M, Jarczak D, Beger C, Manns MP, Krüger M. Inhibition of hepatitis C virus translation and subgenomic replication by siRNAs directed against highly conserved HCV sequence and cellular HCV cofactors. J Hepatol 2005; 43: 225-234. [PubMed]

Kustikova O, Fehse B, Modlich U, Yang M, Düllmann J, Kamino K, von Neuhoff N, Schlegelberger B, Li Z, Baum C. Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking. Science 2005;308:1171-74. [PubMed]

Lechel A, Satyanarayana A, Ju Z, Plentz RR, Schaetzlein S, Rudolph C, Wilkens L, Wiemann SU, Saretzki G, Malek NP, Manns MP, Buer J, Rudolph KL. The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo. EMBO Rep 2005; 6:275-81. [PubMed]

Lehmann U, Berg-Ribbe I, Wingen LU, Brakensiek K, Becker T, Klempnauer J, Schlegelberger B, Kreipe H, Flemming P. Distinct methylation patterns of benign and malignant liver tumors revealed by quantitative methylation profiling. Clin Cancer Res 2005;11:3654-60. [PubMed]

Modlich U, Kustikova OS, Schmidt M, Rudolph C, Meyer J, Li Z, Kamino K, von Neuhoff N, Schlegelberger B, Kuehlcke K, Bunting KD, Schmidt S, Deichmann A, von Kalle C, Fehse B, Baum C. Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis. Blood 2005;105:4235-46. [PubMed]

Plentz RR, Schlegelberger B, Flemming P, Gebel M, Kreipe H, Manns MP, Rudolph KL, Wilkens L. Telomere shortening correlates with increasing aneuploidy of chromosome 8 in human hepatocellular carcinoma. Hepatology 2005;42:522-6. [PubMed]

Obermeier F, Dunger N, Strauch UG, Hofmann C, Bleich A, Grunwald N. Hedrich HJ, Aschenbrenner E, Schlegelberger B, Rogler G, Schölmerich J, Falk W. CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation. Gastroenterology 2005;129:913-27. [PubMed]

Pilat S, Carotta S, Schiedlmeier B, Kamino K, Mairhofer A, Will E, Modlich U, Steinlein P, Ostertag W, Baum C, Beug H, Klump H. HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. Proc Natl Acad Sci USA 2005;102:12101-6. [PubMed]

Reiter A, Walz C, Watmore A, Schoch C, Blau I, Schlegelberger B, Berger U, Telford N, Aruliah S, Yin JA, Vanstraelen D, Barker HF, Taylor PC, O'Driscoll A, Benedetti F, Rudolph C, Kolb HJ, Hochhaus A, Hehlmann R, Chase A, Cross NC. The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2. Cancer Res 2005;65:2662-2667. [PubMed]

Rudolph C, Hegazy AN, von Neuhoff N, Steinemann  D, Schrock  E, Stripecke R, Klein C, Schlegelberger B. Karyotypic evolution in a BCR-ABL transduced mouse cell line. Cancer Genet Cytogenet 2005;161:51-6. [PubMed]

Schnakenberg E, Mehles A, Cario G, Rehe K, Seidemann K, Schlegelberger B, Elsner HA, Welte KH, Schrappe M, Stanulla M. Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population. BMC Medical Genetics 2005;6:23. [PubMed]

Sharma AD, Cantz T, Richter R, Eckert K, Henschler R, Wilkens L, Jochheim-Richter A, Aresniev L, Ott M. Human cord blood stems cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver. Am J Pathol 2005;167:555-64. [PubMed]

Skawran B, Schubert S, Dechend F, Vervoorts J, Nayernia K, Lüscher B, Schmidtke J. Characterization of a human TSPY promoter. Mol Cell Biochem 2005;276:159-67. [PubMed]

von Neuhoff N, Pich A. Mass spectrometry-based methods for biomarker detection and analysis. Drug Discov Today Technol 2005;2:361-7.

Werwitzke S, Trick D, Kamino K, Matthias T, Kniesch K, Schlegelberger B, Schmidt RE, Witte T. Inhibition of lupus disease by anti-double-stranded DNA antibodies of the IgM isotype in the (NZB x NZW)F1 mouse. Arthritis Rheum 2005;52:3629-38. [PubMed]

Wiemann SU, Satyanarayana A, Buer J, Kamino K, Manns MP, Rudolph KL. Contrasting effects of telomere shortening on organ homeostasis, tumor suppression, and survival during chronic liver damage. Oncogene 2005;24:1501-9. [PubMed]

Wilkens L, Gerr H, Gadzicki D, Kreipe H, Schlegelberger B. Standardised fluorescence in situ hybridisation in cytological and histological specimens. Virchows Arch 2005;447:586-92. [PubMed]

Reviews und Buchbeiträge

Gadzicki D, Schlegelberger B. Das interdisziplinäre Beratungskonzept bei familiärer Belastung für Brust- und Eierstockkrebs. gyn 2005;10:286-294.

Gadzicki D, Neises M, Schlegelberger B. Das interdisziplinäre Beratungskonzept bei familiärer Belastung für Brust- und Eierstockkrebs. Forum DKG 2005;5:43-45.

Schlegelberger B, Hoffrage U. Implikationen der genetischen Beratung bei Hochrisiko-Familien für erblichen Brust- und Eierstockkrebs. In: Gerhardus A, Schleberger H, Schlegelberger B, Schwartz FW, editors. BRCA – Erblicher Brust- und Eierstockkrebs. Beratung – Testverfahren – Kosten. Heidelberg. Springer Medizin Verlag; 2005. p. 33-58.

Schleberger H, Gadzicki D, Schlegelberger B, Gerhardus A. Systematischer Vergleich der Testverfahren. In: Gerhardus A, Schleberger H, Schlegelberger B, Schwartz FW, editors. BRCA – Erblicher Brust- und Eierstockkrebs. Beratung – Testverfahren – Kosten. Heidelberg. Springer Medizin Verlag; 2005. p. 59-139.

Gerhardus A, Schleberger H, Schlegelberger B, Schwartz FW, editors. BRCA – Erblicher Brust- und Eierstockkrebs. Beratung – Testverfahren – Kosten. Heidelberg. Springer Medizin Verlag; 2005.

Beger C, Ramadani M, Meyer S, Leder G, Krüger M, Welte K, Gansauge F, Beger HG. Down-regulation of BRCA1 in chronic pancreatitis and sporadic pancreatic adenocarcinoma. Clin Cancer Res 2004;10:3780-7. [PubMed]

Bleich A, Mähler M, Most C, Leiter EH, Liebler-Tenorio E, Elson CO, Hedrich HJ, Schlegelberger B, Sundberg JP. Refined histopathologic scoring system improves power to detect colitis QTL in mice. Mammalian Genome 2004;15:865-71. [PubMed]

Dorsch M, Wedekind D, Kamino K, Hedrich HJ. Orthotopic transplantation of rat ovaries as a tool for strain rescue. Lab Anim 2004;38:307-12. [PubMed]

Engelmann J, Janke V, Volk J, Leyhausen G, von Neuhoff N, Schlegelberger B, Geurtsen W. Effects of BisGMA on glutathione metabolism and apoptosis in human gingival fibroblasts in vitro. Biomaterials 2004;25:4573-80. [PubMed]

Fedrowitz M, Kamino K, Löscher W. Significant differences in the effects of magnetic field exposure on 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in two substrains of Sprague-Dawley rats. Cancer Res 2004;64:243-251. [PubMed]

Frank O, Rudolph C, Heberlein C, von Neuhoff N, Schröck E, Schlegelberger B, Fehse B, Ostertag W, Stocking C, Baum C. Tumor cells escape suicide gene therapy by genetic and epigenetic instability. Blood 2004;104:3543-9. [PubMed]

Gadzicki D, Müller-Vahl KR, Heller D, Ossege S, Nöthen MM, Hebebrand J, Stuhrmann M. Tourette syndrome is not caused by mutations in the central cannabinoid receptor (CNR1) gene. Am J Med Genet B Neuropsychiatr Genet 2004;127:97-103. [PubMed]

Giagounidis AA, Germing U, Haase S, Hildebrandt B, Schlegelberger B, Schoch C, Wilkens L, Heinsch M, Willems H, Aivado M, Aul C. Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del(5q) including band q31. Leukemia 2004;18:113-119. [PubMed]

Hehlmann R, Berger U, Aul C, Büchner T, Döhner H, Ehninger G, Ganser A, Gökbuget N, Hoelzer D, Uberla K, Gassmann W, Ludwig WD, Rieder H, Kneba M, Hochhaus A, Reiter A, Hiddemann W, Ottmann OG, Germing U, Adelhard K, Dugas M, Dirschedl P, Messerer D, Böhme A, Harrison-Neu E, Griesshammer M, Kienast J, Kolb HJ, Ho AD, Hallek M, Neubauer A, Schlegelberger B, Niederweiser D, Heil G, Müller T, Hasford J. The German Competence Network “Acute and chronic leukemias”. Leukemia 2004;18:665-9. [PubMed]

Heuser M, Wingen LU, Ritter J, Neubauer A, Schlegelberger B. Die Plattform „Signaltransduktion, Genomics/Proteomics“. Med Welt 2004;55:307-310.

Korangy F, Ormandy LA, Bleck J, Klempnauer J, Wilkens L, Manns M, Greten T. Spontaneous tumor-specific humoral and cellular immune response to NY-ESO-1 in hepatocellular carcinoma. Clin Cancer Res 2004;10:4332-4341. [PubMed]

Länger B, Dorsch M, Gärtner K, Wedekind D, Kamino K, Hedrich HJ. WKY/Ztm-ter: a new rat inbred strain on the WKY/Ztm genetic background with congenital teratomas. Lab Anim 2004;38:425-31. [PubMed]

Mengel M, Jonigk D, Wilkens L, Radermacher J, von Wasielewski R, Lehmann U, Haller H, Mihatsch M, Kreipe H. Chimerism of metanephric adenoma but not of carcinoma in kidney transplants. Am J Pathol 2004;165:2079-85. [PubMed]

Ritgen M, Stilgenbauer S, von Neuhoff N, Humpe A, Brüggemann M, Pott C, Raff T, Krober A, Bunjes D, Schlenk R, Schmitz N, Döhner H, Kneba M, Dreger P. Graft-versus-leukemia activity may overcome therapeutic resistance of chronic lymphocytic leukemia with unmutated immunoglobulin variable heavy-chain gene status: implications of minimal residual disease measurement with quantitative PCR. Blood 2004;104:2600-2. [PubMed]

Rudolph C, Steinemann D, von Neuhoff N, Gadzicki D, Ripperger T, Drexler HG, Mrasek K, Liehr T, Claussen U, Emura M, Schröck E, Schlegelberger B. Molecular cytogenetic characterization of the mantle cell lymphoma (MCL) cell line GRANTA 519. Cancer Genet Cytogenet 2004;153:144-50. [PubMed]

von Neuhoff N, Kaiser T, Wittke S, Krebs R, Pitt A, Burchard A, Sundmacher A, Schlegelberger B, Kolch W, Mischak H. Mass spectrometry for the detection of differentially expressed proteins: a comparison of surface-enhanced laser desorption/ionization and capillary electrophoresis/mass spectrometry. Rapid Commun Mass Spectrom 2004;18:149-156. [PubMed]

Wilkens L, Flemming P, Gebel M, Bleck J, Terkamp C, Wingen L, Kreipe H, Schlegelberger B. Induction of aneuploidy by increasing chromosomal instability during dedifferentiation of hepatocellular carcinoma. Proc Natl Acad Sci 2004;101:1309-14. [PubMed]

Willerding-Mollmann S, Wilkens L, Schlegelberger B, Kaiser U. Azathioprin-assoziiertes myelodysplastisches Syndrom mit zytogenetischen Aberrationen. Dtsch Med Wochenschr 2004;129:1246-8. [PubMed]

Yonou H, Yokose T, Yoshikawa T, Kanomata N, Kamijo T, Hasebe T, Nagai K, Ito H, Yamasaki A, Hatano T, Ogawa Y, Emura M, Ochiai A. Engraftment of adult human lung tissue in nonobese diabetic/severe combined immunodeficient mice: a novel lung epithelial regeneration model. Pathobiology 2004;71:93-102. [PubMed]

Zhang Y, Zeleznik-Le N, Emmanuel N, Jayathilaka N, Chen J, Strissel P, Strick R, Li L, Neilly MB, Taki T, Hayashi Y, Kaneko Y, Schlegelberger B, Rowley JD. Characterization of genomic breakpoints in MLL and CBP in leukemia patients with t(11;16). Genes Chromosomes Cancer 2004;41:257-65. [PubMed]

Beger C, Gerdes K, Lauten M, Tissing WJ, Fernandez-Munoz I, Schrappe M, and Welte K. Expression and structural analysis of glucocorticoid receptor isoform gamma in human leukaemia cells using an isoform-specific real-time PCR approach. Brit J Haematol 2003;122:245-252. [PubMed]

Gesk S, Martin-Subero JI, Harder L, Luhmann B, Schlegelberger B, Calasanz MJ, Grote W, Siebert R. Molecular cytogenetic detection of chromosomal breakpoints in T-cell receptor gene loci. Leukemia 2003; 17:738-745. [PubMed]

Haferlach T, Schoch C, Loffler H, Gassmann W, Kern W, Schnittger S, Fonatsch C, Ludwig WD, Wuchter C, Schlegelberger B, Staib P, Reichle A, Kubica U, Eimermacher H, Balleisen L, Gruneisen A, Haase D, Aul C, Karow J, Lengfelder E, Wormann B, Heinecke A, Sauerland MC, Buchner T, Hiddemann W. Morphologic dysplasia in de novo acute myeloid leukemia (AML) is related to unfavorable cytogenetics but has no independent prognostic relevance under the conditions of intensive induction therapy: results of a multiparameter analysis from the German AML Cooperative Group studies. J Clin Oncol 2003;21:256-265. [PubMed]

Häussler S, Rohde M, von Neuhoff N, Nimtz M, Steinmetz I. Structural and functional cellular changes induced by Burkholderia pseudomallei rhamnolipid. Infect Immun 2003;5:2970-2975. [PubMed]

Ishii G, Sangai T, Oda T, Aoyago Y, Hasebe T, Kanomata N, Endoh Y, Okumura C, Okuhara Y, Magae J, Emura M, Ochiya T, Ochiai A. Bone marrow derived myofibroblasts contribute to the cancer induced stromal reaction. Biochem Biophys Res Commun 2003;309:232–240. [PubMed]

Janke V, von Neuhoff N, Schlegelberger B, Leyhausen G, Geurtsen W. TEGDMA causes apoptosis in primary human gingival fibroblasts. J Dent Res 2003;82:814-818. [PubMed]

Julian-Reynier C, Welkenhuysen M, Hagoel L, Decruyenaere M, Hopwood P on behalf of the CRISCOM Working Group (Mitglied: Schlegelberger B). Risk communication strategies: state of the art and effectiveness in the context of cancer genetic services. Eur J Hum Genet 2003;11:725-736. [PubMed]

Lauten M, Beger C, Gerdes K, Asgedom G, Kardinal C, Welte K, and Schrappe M. Expression of heat shock protein 90 in glucocorticoid sensitive and resistant childhood acute lymphoblastic leukaemia. Leukemia 2003;17:1551-1556. [PubMed]

Pauluhn J, Emura M, Mohr U, Rosenbruch M. Inhalation toxicity of propineb. Part II: Results of mechanistic studies in rats. Inhal Toxicol 2003;15:435-460. [PubMed]

Schagdarsurengin U, Wilkens L, Steinemann D, Flemming P, Kreipe H, Pfeifer G, Schlegelberger B, Dammann R. Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma. Oncogene 2003;22:1866-1871. [PubMed]

Schmutzler R, Schlegelberger B, Meindl A, Gerber W-D, Kiechle M. Beratung, Genetische Testung und Prävention von Frauen mit einer familiären Belastung für das Mamma- und Ovarialkarzinom. Interdisziplinäre Empfehlungen des Konsortiums “Familiärer Brust- und Eierstockkrebs” der Deutschen Krebshilfe. Zentralbl Gynakol 2003;125:494-506. [PubMed]

Schmutzler R, Schlegelberger B, Meindl A, Gerber W-D, Kiechle M. Beratung, Genetische Testung und Prävention von Frauen mit einer familiären Belastung für das Mamma- und Ovarialkarzinom. Interdisziplinäre Empfehlungen des Verbundprojektes “Familiärer Brust- und Eierstockkrebs” der Deutschen Krebshilfe. medgen 2003;15:385-395.

Son WC, Kamino K, Lee YS, Kang KS. Strain-specific mammary proliferative lesion development following lifetime oral administration of ochratoxin A in DA and Lewis rats. Int J Cancer 2003;105:305-311. [PubMed]

Son WC, Kamino K, Lee YS, Kang KS. Lack of effects of sodium 2-mercaptoethane sulfonate (mesna) on Ochratoxin A induced renal tumorigenicity following life-time oral administration of Ochratoxin A in DA and Lewis rats. Toxicol Lett 2003;142:19-27. [PubMed]

Steinemann D, Gesk S, Zhang Y, Harder L, Pilarsky C, Hinzmann B, Martin-Subero JI, Calasanz MJ, Mungall A, Rosenthal A, Siebert R, Schlegelberger B. Identification of candidate tumor suppressor genes in 6q27 by combined deletion mapping and electronic expression profiling in lymphoid neoplasms. Genes Chromosomes Cancer 2003;37:421-6. [PubMed]

Streetz KL, Tacke F, l. Leifeld I, Wüstefeld T, Graw A, Klein C, Kamino K, Spengler U, Kreipe H, Kubicka S, Müller W, Manns MP, Trautwein C. Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases. Hepatology 2003;38:218-229. [PubMed]

Weng L, Gesk S, Martin Subero JI, Harder L, Schlegelberger B, Grote W, Siebert R, Dyer MJ. Interphase cytogenetic characterization of aberrations in the long arm of chromosome 1 in B-cell lymphoid malignancies. Cancer Genet Cytogenet 2003;144:83-84.  [PubMed]

Wilkens L, Tchinda J, Burkhardt D, Kreipe H. Significant hybridization differences in comparative genomic hybridization due to nucleotides used for DNA labelling and to DNA chosen for cohybridization. Pathobiology 2003;70:204-208. [PubMed]

Bücher, Buchbeiträge, Übersichtsartikel

Wilkens L, Brinkmann M, von Neuhoff N, Tillmann HL, Schulz TF. Viren und die Entstehung hämatologischer Neoplasien;. in Molekularmedizinische Grundlagen von hämatologischen Neoplasien, Springer 2003.

Martin-Subero JI, Gesk S, Harder L, Sonoki T, Tucker PW, Schlegelberger B, Grote W, Novo FJ, Calasanz MJ, Hansmann ML, Dyer MJ, Siebert R. Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma. Blood 2002;99:1474-1477.

Nobile C, Hinzmann B, Scannapieco P, Siebert R, Zimbello R, Perez-Tur J, Sarafidou T, Moschonas NK, French L, Deloukas P, Ciccodicola A, Gesk S, Poza JJ, Nigro CL, Seri M, Schlegelberger B, Rosenthal A, Valle G, de Munain AL, Tassinari CA, Michelucci R. Identification and characterization of a novel human brain-specific gene, homologous to S. scrofa tmp83.5, in the chromosome 10q24 critical region for temporal lobe epilepsy and spastic paraplegia. Gene 2002;282:87-94.

Wilkens L, Bredt M, Flemming P, Mengel M, Klempnauer J, Kreipe H, Flemming P. Detection of chromosomal aberrations in well-differentiated hepatocellular carcinoma by bright-field in situ hybridization. Mod Pathol 2002,15:470-5.

Wilkens L, Bredt M, Flemming P, Mengel M, Becker T, Klempnauer J, Kreipe H. Comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH) in the diagnosis of hepatocellular carcinoma. J Hepatobiliary Pancreat Surg 2002,9:304-11.

Bücher, Buchbeiträge, Übersichtsartikel

Kamino K, Böhm B, Thomale J. Comparison between XPA-knockout and wt mice in chemically induced haematopoietic neoplasms. In: Heinrich U, Mohr U, editors-in chief. Crucial Issues in Inhalation Research – Mechanistic, Clinical and Epidemiologic. Stuttgart: Fraunhofer IRB Verlag; 2002.

Emura M. Stem cells of the respiratory tract. Paed Resp 2002; Rev. 3:1-6.

Flemming P, Wilkens L, Kreipe H. Histopathologische Diagnostik primärer Lebertumoren. Pathologe 2001; 22:184-190.

Kahl C, Gesk S, Harder L, Harbott J, French L, Deloukas P, Grote W, Schlegelberger B, Siebert R. Detection of translocations involving the HOX11/TCL3-locus in 10q24 by interphase fluorescence in situ hybridization. Cancer Genet Cytogenet 2001; 129:80-4.

Kamino K, Tillmann T, Mohr U. Spectrum and age-related incidence of spontaneous tumours in a colony of Han:AURA hamsters. Exp Toxic Pathol 2001; 52:539-44.

Kamino K. Influence of X-rays on transgenerational lung tumorigenesis in CBA mice. J Nara Med Assoc 2001; 52:1-8.

Kamino K, Tillmann T, Boschmann E, Mohr U. Age related incidence of spontaneous non-neoplastic lesions in a colony of Han:AURA hamsters. Exp Toxic Pathol 2001, 53:157-64.

Martin-Subero JI, Harder L, Gesk S, Schoch R, Novo FJ, Grote W, Calasanz MJ, Schlegelberger B, Siebert R. Amplification of ERBB2, RARA, and TOP2A genes in a myelodysplastic syndrome transforming to acute myeloid leukemia. Cancer Genet Cytogenet 2001; 127:174-6.

Martin-Subero JI, Siebert R, Harder L, Gesk S, Schwindt P, Bräuninger A, Willenbrock K, Steinemann D, Tiemann M, Calasanz MJ, Grote W, Ludwig WD, Hansmann ML, Schlegelberger B. Cytogenetic and molecular characterization of a patient with simultaneous B-cell chronic lymphocytic leukemia and peripheral T-cell lymphoma. Amer J Hematol 2001; 68:276-9.

McPherson JD, Marra M, Hillier L, Waterston RH, Chinwalla A, Wallis J, Sekhon M, Wylie K, Mardis ER, Wilson RK, Fulton R, Kucaba TA, Wagner-McPherson C, Barbazuk WB, Gregory SG, Humphray SJ, French L, Evans RS, Bethel G, Whittaker A, Holden JL, McCann OT, Dunham A, Soderlund C, Scott CE, Bentley DR, Schuler G, Chen HC, Jang W, Green ED, Idol JR, Maduro VV, Montgomery KT, Lee E, Miller A, Emerling S, Kucherlapati, Gibbs R, Scherer S, Gorrell JH, Sodergren E, Clerc-Blankenburg K, Tabor P, Naylor S, Garcia D, de Jong PJ, Catanese JJ, Nowak N, Osoegawa K, Qin S, Rowen L, Madan A, Dors M, Hood L, Trask B, Friedman C, Massa H, Cheung VG, Kirsch IR, Reid T, Yonescu R, Weissenbach J, Bruls T, Heilig R, Branscomb E, Olsen A, Doggett N, Cheng JF, Hawkins T, Myers RM, Shang J, Ramirez L, Schmutz J, Velasquez O, Dixon K, Stone NE, Cox DR, Haussler D, Kent WJ, Furey T, Rogic S, Kennedy S, Jones S, Rosenthal A, Wen G, Schilhabel M, Gloeckner G, Nyakatura G, Siebert R, Schlegelberger B, Korenberg J, Chen XN, Fujiyama A, Hattori M, Toyoda A, Yada T, Park HS, Sakaki Y, Shimizu N, Asakawa S, Kawasaki K, Sasaki T, Shintani A, Shimizu A, Shibuya K, Kudoh J, Minoshima S, Ramser J, Seranski P, Hoff C, Poustka A, Reinhardt R, Lehrach H. A physical map of the human genome. The International Human Genome Mapping Consortium. Nature 2001; 409:934-41.

Metzke-Heidemann S, Harder L, Gesk S, Schoch R, Jenisch S, Grote W, Siebert R, Schlegelberger B. Integration of amplified BCR/ABL fusion genes into the short arm of chromosome 17 as a novel mechanism of disease progression in chronic myeloid leukemia. Genes Chrom Cancer 2001; 31: 10-14.

Sanchez-Izquierdo D, Siebert R, Harder L, Marugan I, Gozzetti A, Price HP, Gesk S, Hernandez-Rivas JM, Benet I, Sole F, Sonoki T, Le Beau MM, Schlegelberger B, Dyer MJ, Garcia-Conde J, Martinez-Climent JA. Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin’s lymphoma by interphase fluorescence in situ hybridization. Leukemia 2001; 15:1475-84.

Satterwhite E, Sonoki T, Willis TG, Harder L, Nowak R, Arriola EL, Liu H, Price HP, Gesk S, Steinemann D, Schlegelberger B, Oscier DG, Siebert R, Tucker PW, Dyer MJ. The BCL11 gene family: involvement of BCL11A in lymphoid malignancies. Blood 2001; 98:3413-20.

Schliephake H, Knebel JW, Aufderheide M, Tauscher M. Use of cultivated osteoprogenitor cells to increase bone formation in segmental mandibular defects: an experimental pilot study in sheep. Int J Oral Maxillofac Surg 2001; 30:531-537.

Schoch C, Haferlach T, Haase D, Fonatsch C, Loffler H, Schlegelberger B, Staib P, Sauerland MC, Heinecke A, Buchner T, Hiddemann W. Patients with de novo acute myeloid leukaemia and complex karyotype aberrations show a poor prognosis despite intensive treatment: a study of 90 patients. Br J Haematol 2001; 112:118-26.

Sonoki T, Harder L, Horsman DE, Karran L, Taniguchi I, Willis TG, Gesk S, Steinemann D, Zucca E, Schlegelberger B, Sole F, Mungall AJ, Gascoyne RD, Siebert R, Dyer MJ. Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies. Blood 2001; 98: 2837-44.

Steinemann D, Siebert R, Harder S, Martin Subero I, Kettwig G, Hinzmann B, Gesk S, Tiemann M, Merz H, Rosenthal A, Grote W, Morris SW, Schlegelberger B. Frequent allelic loss of the BCL10 gene in lymphomas with the t(11;14)(q13;q32). Leukemia 2001; 15: 474-5.

Stumm M, von Ruskowsky A, Siebert R, Harder S, Varon R, Wieacker P, Schlegelberger B. No evidence for deletions of the NBS1 gene in lymphomas. Cancer Genet Cytogenet 2001; 126:60-2.

Viardot A, Martin-Subero JI, Siebert R, Harder S, Gesk S, Bentz M, Schlegelberger B. Detection of secondary genetic aberrations in follicle center cell derived lymphomas: assessment of the reliability of comparative genomic hybridization and standard chromosome analysis. Leukemia 2001; 15:177-83.

Wehner LE, Schröder N, Kamino K, Friedrich U, Biesinger B, Rüther U. Herpesvirus saimiri tip gene causes T-cell lymphomas in transgenic mice. DNA Cell Biol 2001; 20:81-8.

Wilkens L, Bredt M, Flemming P, Becker T, Kubicka S, Kreipe H. Differentiation of liver cell adenomas from well differentiated hepatocellular carcinomas by comparative genomic hybridisation. J Pathol 2001; 193:476-482.

Wilkens L, Bredt M, Flemming P, Schwarze Y, Becker T, Klempnauer J, Kreipe H. Diagnostic impact of fluorescence in situ hybridization in the differentiation of hepatocellular adenoma and well differentiated hepatocellular carcinoma. J Mol Diagn 2001; 3:68-73.

Bücher, Buchbeiträge, Übersichtsartikel

Schlegelberger B. Cytogenetic subtyping of diffuse large B-cell lymphomas. Ann Hematol 2001; 80 Suppl 3:B32-4.