Publikationen des Instituts

 

 

 

Publikationen 2013 

 

Khalil AA, Tsikas D, Akolekar R, Jordan J, Nicolaides KH. Asymmetric dimethylarginine, arginine and homoarginine at 11-13 weeks' gestation and preeclampsia: a case-control study. J Hum Hypertens 2013; 27: 38-43

 

 

 

 

 

Publikationen 2012

 

Jordan J, Heusser K, Brinkmann J, Tank J. Electrical carotid sinus stimulation in treatment resistant arterial hypertension. Auton Neurosci 2012; 172: 31-6

 

Holstein A, Beil W, Kovacs P. CYP2C metabolism of oral antidiabetic drugs - impact on pharmacokinetics, drug interactions and pharmacogenetic aspects. Expert Opin Drug Metab Toxicol 2012; 8: 1549-63

 

Jordan J, Biaggioni I. Genetic influences on human baroreflex regulation. Auton Neurosci 2012; 172: 23-5

 

Menne J, Jordan J, Linnenweber-Held S, Haller H. Resistant hypertension: baroreflex stimulation as a new tool. Nephrol Dial Transplant 2012 Dec 6. [Epub ahead of print]

 

Jordan J, Birkenfeld AL. Comment on: Vila et al. B-Type Natriuretic Peptide Modulates Ghrelin, Hunger, and Satiety in Healthy Men. Diabetes 2012;61:2592-2596. Diabetes 2012; 61: e22

 

Engeli S, Birkenfeld AL, Badin PM, Bourlier V, Louche K, Viguerie N, Thalamas C, Montastier E, Larrouy D, Harant I, de Glisezinski I, Lieske S, Reinke J, Beckmann B, Langin D, Jordan J, Moro C. Natriuretic peptides enhance the oxidative capacity of human skeletal muscle. J Clin Invest 2012; 122: 4675-9

 

Tsikas D. Letter by tsikas regarding article, "dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase". Circulation 2012; 126: e348

 

Lochner S, Kirch W, Schindler C. Managing hypertension among nursing-home residents and community-dwelling elderly in Germany: a comparative pharmacoepidemiological study. Eur J Clin Pharmacol 2012; 68: 867-75

 

Haufe S, Engeli S, Jordan J. Letter by Haufe et al regarding article, "adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation". Circ Heart Fail 2012; 5: e100

 

Tsikas D. Potential problems and pitfalls with the use of S-nitrosoglutathione and other S-nitrosothiols in physiology-oriented basic science. J Physiol 2012; 590: 6247-8

 

Engeli S. The clinical pharmacology of obesity. Ther Adv Endocrinol Metab 2012; 3: 83-4

 

Jordan J, Boye SW, Breton SL, Keefe DL, Engeli S, Prescott MF. Antihypertensive treatment in patients with class 3 obesity. Ther Adv Endocrinol Metab 2012; 3: 93-8

  

Tsikas D. Measurement of nitrite in plasma and serum: still a challenging analytical task. Clin Chem Lab Med 2012; 50: 2049-51

 

Brinkmann J, Heusser K, Schmidt BM, Menne J, Klein G, Bauersachs J, Haller H, Sweep FC, Diedrich A, Jordan J, Tank J. Catheter-Based Renal Nerve Ablation and Centrally Generated Sympathetic Activity in Difficult-to-Control Hypertensive Patients: Prospective Case Series. Hypertension 2012; 60: 1485-90

 

Schindler C, Barthel A, Fischer S, Bornstein SR, Kirch W. Nutzen und Risiken der modernen Pharmakotherapie des Typ-2-Diabetes. Internist 2012; 53: 478-87

 

Tsikas D, Evans CE, Denton TT, Mitschke A, Gutzki FM, Pinto JT, Khomenko T, Szabo S, Cooper AJ. Stable isotope gas chromatography-tandem mass spectrometry determination of aminoethylcysteine ketimine decarboxylated dimer in biological samples. Anal Biochem 2012; 430: 4-15

 

Engeli S, Blüher M, Jumpertz R, Wiesner T, Wirtz H, Bosse-Henck A, Stumvoll M, Batkai S, Pacher P, Harvey-White J, Kunos G, Jordan J. Circulating anandamide and blood pressure in patients with obstructive sleep apnea. J Hypertens 2012; 30: 2345-51

 

Schroeder C, Jordan J. Norepinephrine Transporter Function and Human Cardiovascular Disease. Am J Physiol Heart Circ Physiol. 2012 Sep 28. [Epub ahead of print]

 

Giustarini D, Milzani A, Dalle-Donne I, Tsikas D, Rossi R. N-Acetylcysteine ethyl ester (NACET): A novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potential. Biochem Pharmacol. 2012 Sep 20. pii: S0006-2952(12)00641-7. doi: 10.1016/j.bcp.2012.09.010. [Epub ahead of print]

 

Nugraha B, Karst M, Engeli S, Gutenbrunner C. Brain-derived neurotrophic factor and exercise in fibromyalgia syndrome patients: a mini review. Rheumatol Int 2012; 32: 2593-9

 

Heberlein A, Leggio L, Stichtenoth D, Hillemacher T. The treatment of alcohol and opioid dependence in pregnant women. Curr Opin Psychiatry 2012; 25: 559-64

 

Böhmer A, Niemann J, Schwedhelm KS, Meyer HH, Gambaryan S, Tsikas D. Potential pitfalls with the use of acetoxy (CH(3)COO) drugs in studies on nitric oxide synthase in platelets. Nitric Oxide 2012 Sep 18;28C:14-16. doi: 10.1016/j.niox.2012.09.002. [Epub ahead of print]

 

Birkenfeld AL, Boschmann M, Engeli S, Moro C, Arafat AM, Luft FC, Jordan J. Atrial natriuretic peptide and adiponectin interactions in man. PLoS One. 2012;7(8):e43238. doi: 10.1371/journal.pone.0043238. Epub 2012 Aug 16

 

Haas V, Schütz T, Engeli S, Schröder C, Westerterp K, Boschmann M. Comparing single-frequency bioelectrical impedance analysis against deuterium dilution to assess total body water. Eur J Clin Nutr 2012; 66: 994-7

 

Großkopf H, Böhmer A, Tsikas D. Letter to the editor: "Role of the human erythrocyte in generation and storage of asymmetric dimethylarginine". Am J Physiol Heart Circ Physiol 2012; 303: H751-2

 

Chobanyan-Jürgens K, Fuchs AJ, Tsikas D, Kanzelmeyer N, Das AM, Illsinger S, Vaske B, Jordan J, Lücke T. Increased asymmetric dimethylarginine (ADMA) dimethylaminohydrolase (DDAH) activity in childhood hypercholesterolemia type II. Amino Acids 2012; 43: 805-11

 

Schindler C, Leuschner S, Schwanebeck U, Kirch W. Characterization of Local Vascular Effects of the Nitric Oxide Inhibitor NG-Monomethyl-L-Arginine on Dorsal Hand Veins. Journal Clin Pharm 2012; 52: 859-69

 

Modun D, Krnic M, Vukovic J, Kokic V, Kukoc-Modun L, Tsikas D, Dujic Z. Plasma nitrite concentration decreases after hyperoxia-induced oxidative stress in healthy humans. Clin Physiol Funct Imaging 2012; 32: 404-8

 

Engeli S, Tsikas D, Lehmann AC, Böhnke J, Haas V, Strauß A, Janke J, Gorzelniak K, Luft FC, Jordan J. Influence of dietary fat ingestion on asymmetrical dimethylarginine in lean and obese human subjects. Nutr Metab Cardiovasc Dis 2012; 22: 720-6

 

Tsikas D, Suchy MT. Assessment of urinary F(2)-isoprostanes in experimental and clinical studies: mass spectrometry versus ELISA. Hypertension 2012; 60: e14

 

Kubo T, Sato T, Noguchi T, Kitaoka H, Yamasaki F, Kamimura N, Shimodera S, Iiyama T, Kumagai N, Kakinuma Y, Diedrich A, Jordan J, Robertson D, Doi YL. Influences of donepezil on cardiovascular system--possible therapeutic benefits for heart failure--donepezil cardiac test registry (DOCTER) study. J Cardiovasc Pharmacol 2012; 60: 310-4

 

Voigt C, Donat CK, Hartig W, Förschler A, Skardelly M, Stichtenoth D, Arendt T, Meixensberger J, Schuhmann MU. Effect of leukotriene inhibitors on evolution of experimental brain contusions. Neuropathol Appl Neurobiol 2012; 38: 354-66

 

Tsikas D, Suchy MT, Niemann J, Tossios P, Schneider Y, Rothmann S, Gutzki FM, Frölich JC, Stichtenoth DO. Glutathione promotes prostaglandin H synthase (cyclooxygenase)-dependent formation of malondialdehyde and 15(S)-8-iso-prostaglandin F(2α). FEBS Lett 2012; 586: 3723-30

 

May M, Mand P, Biertz F, Hummers-Pradier E, Kruschinski C. A survey to assess family physicians' motivation to teach undergraduates in their practices. PLoS One 2012; 7: e45846

 

Jordan J, Tank J. Go for the cardiovascular 'physionom'. J Hypertens 2012; 30: 1699-701

 

Tank J, Heusser K, Malehsa D, Hegemann K, Haufe S, Brinkmann J, Tegtbur U, Diedrich A, Bara C, Jordan J, Strüber M. Patients with continuous-flow left ventricular assist devices provide insight in human baroreflex physiology. Hypertension 2012; 60: 849-55

 

Jordan J, Grassi G. Sometimes you simply have to wait: sympathetic activity in women with hypertensive pregnancies. J Hypertens 2012; 30: 1111-3

 

Tsikas D, Flentje M, Niemann J, Böhmer A, Stichtenoth DO. Extra-platelet NO and NO+-containing drugs are potent inhibitors of platelet aggregation in humans by cGMP-dependent and cGMP-independent mechanisms. Blood 2012; 119: 5337-9

 

Jordan J, Yumuk V, Schlaich M, Nilsson PM, Zahorska-Markiewicz B, Grassi G, Schmieder RE, Engeli S, Finer N. Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension: obesity and difficult to treat arterial hypertension. J Hypertens 2012; 30: 1047-1055

 

Tsikas D, Flentje M, Niemann J, Modun D. Antioxidants and endothelial dysfunction in young and elderly people: is flow-mediated dilation useful to assess acute effects? Hypertension 2012; 60: e5

 

Frenzel H, Bohlender J, Pinsker K, Wohlleben B, Tank J, Lechner SG, Schiska D, Jaijo T, Rüschendorf F, Saar K, Jordan J, Millán JM, Gross M, Lewin GR. A genetic basis for mechanosensory traits in humans. PLoS Biol 2012; 10: e1001318

 

Jordan J, Engeli S. Obesity, hypertension, and cardiovascular health: is there anything poor Cassandra tries to tell us? J Hypertens 2012; 30: 1103-5

 

Tsikas D, Stichtenoth DO. Dietary eicosapentaenoic acid (EPA) to produce antileukemic cyclopentenone prostaglandin J3? Blood 2012 22; 119: 2967-8

 

Utz W, Engeli S, Haufe S, Kast P, Böhnke J, Haas V, Hermsdorf M, Wiesner S, Pofahl M, Traber J, Luft FC, Boschmann M, Jordan J, Schulz-Menger J. Moderate dietary weight loss reduces myocardial steatosis in obese and overweight women. Int J Cardiol 2012 Apr 9. [Epub ahead of print]

 

Boschmann M, Nussberger J, Engeli S, Danser AH, Yeh CM, Prescott MF, Dahlke M, Jordan J. Aliskiren penetrates adipose and skeletal muscle tissue and reduces renin-angiotensin system activity in obese hypertensive patients. J Hypertens 2012; 30: 561-6

 

Luedtke A, Boschmann M, Colpe C, Engeli S, Adams F, Birkenfeld AL, Haufe S, Rahn G, Luft FC, Schmidt HH, Jordan J. Thiazolidinedione response in familial lipodystrophy patients with LMNA mutations: a case series. Horm Metab Res 2012; 44: 306-11

 

Tsikas D, Zoerner AA, Haufe S, Engeli S, Stichtenoth DO, Jordan J. Microdialysis of prostaglandins, thromboxane, and other eicosanoids: recall past knowledge. Hypertension 2012; 59: e39. Epub 2012 Mar 5

 

Bailey CJ, Day C, Campbell IW, Schindler C: Glycaemic control and cardiovascular outcome trials in type 2 diabetes. British Journal of Diabetes Vascular Disease 2012; 4: 161-64

 

Böhmer A, Großkopf H, Jordan J, Tsikas D. Human hemoglobin does not contain asymmetric dimethylarginine (ADMA). Nitric Oxide 2012; 27: 72-4

 

Tsikas D, Böhmer A, Großkopf H, Beckmann B, Dreißigacker U, Jordan J, Maassen N. Clinical-chemistry laboratory relevant hemolysis is unlikely to compromise human plasma concentration of free asymmetric dimethylarginine (ADMA). Clin Biochem 2012 Mar 23. [Epub ahead of print]

 

Böhmer A, Beckmann B, Sandmann J, Tsikas D. Doubts concerning functional endothelial nitric oxide synthase in human erythrocytes. Blood 2012; 119: 1322-3

 

Haschemi Nassab M, Mitschke A, Suchy MT, Gutzki FM, Zoerner AA, Rhein M, Hillemacher T, Frieling H, Jordan J, Tsikas D. Stable-isotope dilution GC-MS method for ethanol in vapour ethanol and microdialysis systems based on carbonate-catalyzed extractive pentafluorobenzoylation. Analyst 2012; 137: 2480-5

 

Zoerner AA, Rakers C, Engeli S, Batkai S, May M, Jordan J, Tsikas D. Peripheral endocannabinoid microdialysis: in vitro characterization and proof-of-concept in human subjects. Anal Bioanal Chem 2012; 402: 2727-35

 

Tsikas D, Niemann J. Nitric oxide, peroxynitrite, S-nitrosothiols and thiols are unlikely to exert their effects on recombinant cyclooxygenase-1 and cyclooxygenase-2 activity in vitro by modifying cysteine moieties. Nitric Oxide 2012; 26: 192-4

 

Jarzimski C, Karst M, Zoerner AA, Rakers C, May M, Suchy MT, Tsikas D, Krauss JK, Scheinichen D, Jordan J, Engeli S. Changes of Blood Endocannabinoids during Anaesthesia: a Special Case for Fatty Acid Amide Hydrolase Inhibition by Propofol? Br J Clin Pharmacol 2012; 74: 54-9

 

Tsikas D, Haufe S, Stichtenoth DO, Jordan J. Nitric oxide and hypertension. J Hypertens 2012; 30: 625-6

 

Wurr M, Nolte I, Stichtenoth D. Investigations on the Significance of Inductable Cyclooxygenase in Atherogenesis in Cholesterol-Fed Rabbits. Pharmacol Pharm 2012; 3: 240-247

 

Engeli S. Central and peripheral cannabinoid receptors as therapeutic targets in the control of food intake and body weight. Handb Exp Pharmacol 2012; 209: 357-81 

 

Chobanyan-Jürgens K, Schwarz A, Böhmer A, Beckmann B, Gutzki FM, Michaelsen JT, Stichtenoth DO, Tsikas D. Renal carbonic anhydrases are involved in the reabsorption of endogenous nitrite. Nitric Oxide 2012; 26: 126-31

 

Tsikas D, Suchy MT, Mitschke A, Beckmann B, Gutzki FM. Measurement of nitrite in urine by gas chromatography-mass spectrometry.. Methods Mol Biol 2012; 844: 277-93

 

Schindler C. New therapeutic efforts and upcoming developments in the field of diabetes medicine and endocrinology. Ther Adv Endocrinol Metab 2012; 3: 51-3

 

Tsikas D, Mitschke A, Gutzki FM. Measurement of 3-nitro-tyrosine in human plasma and urine by gas chromatography-tandem mass spectrometry. Methods Mol Biol. 2012; 828: 255-70

 

Stieger N, Worthmann K, Teng B, Engeli S, Das AM, Haller H, Schiffer M. Impact of high glucose and transforming growth factor-β on bioenergetic profiles in podocytes. Metabolism 2012; 61: 1073-86

 

Tsikas D, Böhmer A, Flentje M. Tetrahydrobiopterin and Endothelial Nitric Oxide Synthase Uncoupling. Hypertension 2012 59: e12

 

Schroeder C, Stabroth C, Luft FC, Jordan J. Adrenergic cardiovascular control before and after removal of stimulatory α-1 adrenoreceptor antibodies. Hypertension 2012; 59: e6-7

 

Böhmer A, Mitschke A, Reib A, Gutzki FM, Tsikas D. 18O-Labeled nitrous acid and nitrite: Synthesis, characterization, and oxyhemoglobin-catalyzed oxidation to 18O-labeled nitrate. Anal Biochem 2012; 421: 770-2

 

Haas V, Engeli S, Hofmann T, Riedl A, Haufe S, Kast P, Wiesner S, Böhnke J, Jordan J, Boschmann M. Variations in truncal body circumferences affect fat mass quantification with bioimpedance analysis. Eur J Clin Nutr 2012; 66: 196-200

 

Rakers C, Zoerner AA, Engeli S, Batkai S, Jordan J, Tsikas D. Stable isotope liquid chromatography-tandem mass spectrometry assay for fatty acid amide hydrolase activity. Anal Biochem 2012; 421: 699-705

 

Haufe S, Utz W, Engeli S, Kast P, Böhnke J, Pofahl M, Traber J, Haas V, Hermsdorf M, Mähler A, Busjahn A, Wiesner S, Otto C, Mehling H, Luft FC, Boschmann M, Schulz-Menger J, Jordan J. Left Ventricular Mass and Function With Reduced-Fat or Reduced-Carbohydrate Hypocaloric Diets in Overweight and Obese Subjects. Hypertension 2012; 59: 70-5

 

Kupfahl C, Tsikas D, Niemann J, Geginat G, Hof H. Production of prostaglandins, isoprostanes and thromboxane by Aspergillus fumigatus: Identification by gas chromatography-tandem mass spectrometry and quantification by enzyme immunoassay. Mol Immunol 2012; 49: 621-7

 

von Leitner EC, Klinke A, Atzler D, Slocum JL, Lund N, Kielstein JT, Maas R, Schmidt-Haupt R, Pekarova M, Hellwinkel O, Tsikas D, D'Alecy LG, Lau D, Willems S, Kubala L, Ehmke H, Meinertz T, Blankenberg S, Schwedhelm E, Gadegbeku CA, Böger RH, Baldus S, Sydow K. Pathogenic Cycle Between the Endogenous Nitric Oxide Synthase Inhibitor Asymmetrical Dimethylarginine and the Leukocyte-Derived Hemoprotein Myeloperoxidase. Circulation 2011; 124: 2735-45

 

Zoerner AA, Batkai S, Suchy MT, Gutzki FM, Engeli S, Jordan J, Tsikas D. Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: Minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. J Chromatogr B Analyt Technol Biomed Life Sci 2012; 883-884: 161-71

 

Marinovic J, Ljubkovic M, Breskovic T, Gunjaca G, Obad A, Modun D, Bilopavlovic N, Tsikas D, Dujic Z. Effects of successive air and nitrox dives on human vascular function. Eur J Appl Physiol 2012; 112: 2131-7

 

Wolf C, Lorenzen JM, Stein S, Tsikas D, Störk S, Weidemann F, Ertl G, Anker SD, Bauersachs J, Thum T. Urinary asymmetric dimethylarginine (ADMA) is a predictor of mortality risk in patients with coronary artery disease. Int J Cardiol 2012; 156: 289-94

 

Tsikas D. Analytical methods for 3-nitrotyrosine quantification in biological samples: the unique role of tandem mass spectrometry. Amino Acids 2012; 42: 45-63

 

Kanzelmeyer N, Tsikas D, Chobanyan-Jürgens K, Beckmann B, Vaske B, Illsinger S, Das AM, Lücke T. Asymmetric dimethylarginine in children with homocystinuria or phenylketonuria. Amino Acids 2012; 42: 1765-72

 

 

 

 

 

Publikationen 2011

 

Migeotte PF, Tank J, Pattyn N, Funtova I, Baevsky R, Neyt X, Prisk GK. Three dimensional ballistocardiography: methodology and results from microgravity and dry immersion. Conf Proc IEEE Eng Med Biol Soc 2011; 2011: 4271-4

 

Picksak G, Stichtenoth DO, Reuter J. Therapy of a common otitis media in the infancy. Med Monatsschr Pharm 2011; 34: 430-2

  

Schroeder C, Tank J, Heusser K, Diedrich A, Luft FC, Jordan J. Physiological phenomenology of neurally-mediated syncope with management implications. PLoS One 2011; 6: e26489. Epub 2011 Oct 25

 

May M, Gueler F, Barg-Hock H, Heiringhoff KH, Engeli S, Heusser K, Diedrich A, Brandt A, Strassburg CP, Tank J, Sweep FC, Jordan J. Liver afferents contribute to water drinking-induced sympathetic activation in human subjects: a clinical trial. PLoS One 2011; 6: e25898. Epub 2011 Oct 7

  

Zoerner AA, Gutzki FM, Batkai S, May M, Rakers C, Engeli S, Jordan J, Tsikas D. Quantification of endocannabinoids in biological systems by chromatography and mass spectrometry: A comprehensive review from an analytical and biological perspective. Biochim Biophys Acta 2011; 1811: 706-23

 

Giustarini D, Tsikas D, Rossi R. Study of the effect of thiols on the vasodilatory potency of S-nitrosothiols by using a modified aortic ring assay. Toxicol Appl Pharmacol 2011; 256: 95-102

 

Janina Willers, Sabine Fasse, Nils Putschky, Henning Zeidler, Hans-Georg Pott, Michael Bernateck, Winfried Demary, Reinhard Hein5 Vu Vi Pham, Rainer Stange, Bernhard Uehleke, Heike Franziska Weidemann, Guido Hoese, Ralf Lichtinghagen, Andreas Hahn. Combined Add-on Supplementation of Omega-3 Fatty Acids, Vitamin E, Vitamin A, Copper, and Selenium in Rheumatoid Arthritis. Food and Nutrition Sciences 2011; 2: 714-723

  

Schroeder C, Jordan J. Norepinephrine uptake mechanisms in cardiovascular disease deserve our attention. J Cardiovasc Pharmacol 2011; 58: 406-8

 

Chobanyan-Jürgens K, Pham VV, Stichtenoth DO, Tsikas D. Elevated dimethylarginine dimethylaminohydrolase (DDAH) activity in rheumatoid arthritis and spondyloarthritis. Nitric Oxide 2011; 25: 436-8

 

da Costa Goncalves AC, Fontes MA, Klussmann E, Qadri F, Janke J, Gollasch M, Schleifenbaum J, Müller D, Jordan J, Tank J, Luft FC, Gross V. Spinophilin regulates central angiotensin II-mediated effect on blood pressure. J Mol Med 2011; 89: 1219-29

 

Tsikas D, Engeli S, Tank J, Stichtenoth DO, Jordan J. Comment on: Ott et al. Reduction in Basal Nitric Oxide Activity Causes Albuminuria. Diabetes 2011; 60: 572-576. Diabetes 2011; 60(8): e21

 

Chobanyan-Jürgens K, Pham VV, Stichtenoth DO, Tsikas D. Asymmetrical dimethylarginine, oxidative stress, and atherosclerosis. Hypertension 2011; 58: 184-5

 

Stichtenoth D. Medikationsfehler: Patientensicherheit und Risikomanagement. In: Von Eiff, W (Hrsg.): Patientenorientierte Arzneimittelversorgung - Sicherheit und Wirtschaftlichkeit des Arzneimittelmanagements. Georg Thieme Verlag, Stuttgart 2011: 64-68

 

Tsikas D, Zoerner AA, Jordan J. Oxidized and nitrated oleic acid in biological systems: Analysis by GC-MS/MS and LC-MS/MS, and biological significance. Biochim Biophys Acta 2011; 1811: 694-705

 

Zoerner AA, Batkai S, Suchy MT, Gutzki FM, Engeli S, Jordan J, Tsikas D. Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: Minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. J Chromatogr B Analyt Technol Biomed Life Sci 2011 Jun 22 [Epub ahead of print]

 

Utz W, Engeli S, Haufe S, Kast P, Hermsdorf M, Wiesner S, Pofahl M, Traber J, Luft FC, Boschmann M, Schulz-Menger J, Jordan J. Myocardial steatosis, cardiac remodelling and fitness in insulin-sensitive and insulin-resistant obese women. Heart 2011; 97: 1585-9

 

Trettin A, Zoerner AA, Böhmer A, Gutzki FM, Stichtenoth DO, Jordan J, Tsikas D. Quantification of acetaminophen (paracetamol) in human plasma and urine by stable isotope-dilution GC-MS and GC-MS/MS as pentafluorobenzyl ether derivative. J Chromatogr B Analyt Technol Biomed Life Sci 2011; 879: 2274-80

 

Zoerner AA, Stichtenoth DO, Engeli S, Batkai S, Winkler C, Schaumann F, Janke J, Holz O, Krug N, Tsikas D, Jordan J, Hohlfeld JM. Allergen Challenge Increases Anandamide in Bronchoalveolar Fluid of Patients With Allergic Asthma. Clin Pharmacol Ther 2011; 90: 388-91

 

Reuter J, Jordan J. The dismal fat, kidney and brain connection: what to do? Hypertens Res 2011; 34: 906-8

 

Haufe S, Jordan J. Obesity can break your heart and more so when you are a woman. J Hypertens 2011; 29: 1295-7

 

Herse F, Fain JN, Janke J, Engeli S, Kuhn C, Frey N, Weich HA, Bergmann A, Kappert K, Karumanchi SA, Luft FC, Muller DN, Staff AC, Dechend R. Adipose tissue-derived soluble fms-like tyrosine kinase 1 is an obesity-relevant endogenous paracrine adipokine. Hypertension 2011; 58: 37-42

 

Batinic T, Utz W, Breskovic T, Jordan J, Schulz-Menger J, Jankovic S, Dujic Z, Tank J. Cardiac Magnetic Resonance Imaging during Pulmonary Hyperinflation in Apnea Divers. Med Sci Sports Exerc 2011; 43: 2095-101

 

Johnston A, Asmar R, Dahlöf B, Hill K, Jones DA, Jordan J, Livingston M, Macgregor G, Sobanja M, Stafylas P, Rosei EA, Zamorano J. Generic and therapeutic substitution: a viewpoint on achieving best practice in Europe. Br J Clin Pharmacol 2011; 72: 727-730

  

Jordan J. Diagnostik und Therapie des Baroreflexversagens. Klinische Neurophysiologie 2011; 42: 92-96

 

Tank J, Heusser K, Diedrich A, Hering D, Luft FC, Busjahn A, Aydin A, Limon J, Narkiewicz K, Jordan J. Beta-2 adrenoreceptor gene polymorphisms and sympathetic outflow in humans. Clin Auton Res 2011; 21: 333-8

 

Haufe S, Engeli S, Kast P, Böhnke J, Utz W, Haas V, Hermsdorf M, Mähler A, Wiesner S, Birkenfeld AL, Sell H, Otto C, Mehling H, Luft FC, Eckel J, Schulz-Menger J, Boschmann M, Jordan J. Randomized comparison of reduced fat and reduced carbohydrate hypocaloric diets on intrahepatic fat in overweight and obese human subjects. Hepatology 2011; 53: 1504-14

  

Tsikas D, Beckmann B, Gutzki FM, Jordan J. Simultaneous gas chromatography-tandem mass spectrometry quantification of symmetric and asymmetric dimethylarginine in human urine. Anal Biochem 2011; 413: 60-2

 

Jordan J, Schlaich M, Redon J, Narkiewicz K, Luft FC, Grassi G, Dixon J, Lambert G, Engeli S; European Society of Hypertension Working Group on Obesity; Australian and New Zealand Obesity Society. European Society of Hypertension Working Group on Obesity: obesity drugs and cardiovascular outcomes. J Hypertens 2011; 29: 189-93

 

Tank J, Biller H, Heusser K, Holz O, Diedrich A, Framke T, Koch A, Grosshennig A, Koch W, Krug N, Jordan J, Hohlfeld JM. Effect of acute ozone induced airway inflammation on human sympathetic nerve traffic: a randomized, placebo controlled, crossover study. PLoS One 2011; 6: e18737

 

Lechner SG, Markworth S, Poole K, Smith ES, Lapatsina L, Frahm S, May M, Pischke S, Suzuki M, Ibañez-Tallon I, Luft FC, Jordan J, Lewin GR. The molecular and cellular identity of peripheral osmoreceptors. Neuron 2011; 69: 332-44

 

Tsikas D, Trettin A, Zörner AA, Gutzki FM. In-source formation of N-acetyl-p-benzoquinone imine (NAPQI), the putatively toxic acetaminophen (paracetamol) metabolite, after derivatization with pentafluorobenzyl bromide and GC-ECNICI-MS analysis. J Chromatogr B Analyt Technol Biomed Life Sci 2011; 879: 1476-84

 

Schmidt LM, Belvisi MG, Bode KA, Bauer J, Schmidt C, Suchy MT, Tsikas D, Scheuerer J, Lasitschka F, Gröne HJ, Dalpke AH. Bronchial epithelial cell-derived prostaglandin E2 dampens the reactivity of dendritic cells. J Immunol 2011; 186: 2095-2105

 

Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS, Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA, Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz I, Schondorff R, Stewart JM, van Dijk JG. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res 2011; 21: 69-72

 

Kirchner GI, Beil W, Bleck JS, Manns MP, Wagner S. Prevalence of Helicobacter pylori and occurrence of gastroduodenal lesions in patients with liver cirrhosis. Int J Clin Exp Med 2011; 4: 26-31

 

Jordan J, Grassi G. Run kidney, run: lifestyle interventions in the prevention of kidney disease. J Hypertens 2011; 29: 437-9

 

Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS, Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA, Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz IJ, Schondorf R, Stewart JM, van Dijk JG. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Auton Neurosci 2011; 161: 46-8

 

Bergmann MW, Haufe S, von Knobelsdorff-Brenkenhoff F, Mehling H, Waßmuth R, Münch I, Busjahn A, Schulz-Menger J, Jordan J, Luft FC, Dietz R. A pilot study of chronic, low-dose epoetin-{beta} following percutaneous coronary intervention suggests safety, feasibility, and efficacy in patients with symptomatic ischaemic heart failure. Eur J Heart Fail 2011; 13: 560-568

 

Birkenfeld AL, Adams F, Schroeder C, Engeli S, Jordan J. Metabolic actions could confound advantageous effects of combined angiotensin II receptor and neprilysin inhibition. Hypertension 2011; 57: e4-5

 

Tsikas D, Sandmann J, Beckmann B. Analysis of NO and its metabolites by mass spectrometry. Comment on 'Detection of nitric oxide in tissue samples by ESI-MS' by Z. Shen, A. Webster, K. J. Welham, C. E. Dyer, J. Greenman and S. J. Haswell. Analyst 2011; 136: 407-10

 

May M, Jordan J. The osmopressor response to water drinking. Am J Physiol Regul Integr Comp Physiol 2011; 300: R40-6

 

Tsikas D. GC-MS and HPLC methods for peroxynitrite (ONOO- and O15NOO-) analysis: a study on stability, decomposition to nitrite and nitrate, laboratory synthesis, and formation of peroxynitrite from S-nitrosoglutathione (GSNO) and KO2. Analyst 2011; 136: 979-87

 

Böhmer A, Jordan J, Tsikas D. High-performance liquid chromatography ultraviolet assay for human erythrocytic catalase activity by measuring glutathione as o-phthalaldehyde derivative. Anal Biochem 2011; 410: 296-303

 

Tsikas D, Stichtenoth DO, Jordan J. Inorganic nitrate for blood pressure lowering? Hypertension 2011; 57: e1-2

 

Zoerner AA, Heusser K, Gutzki FM, Mitschke A, Tank J, Stichtenoth DO, Jordan J, Tsikas D. Unique pentafluorobenzylation and collision-induced dissociation for specific and accurate GC-MS/MS quantification of the catecholamine metabolite 3,4-dihydroxyphenylglycol (DHPG) in human urine. J Chromatogr B Analyt Technol Biomed Life Sci 2011; 879: 1444-56

  

Tsikas D. Comments on the article "Nitrosylated human serum albumin (SNO-HSA) induces apoptosis in tumor cells (Nitric Oxide 22 (2010) 259-265)". Nitric Oxide 2011; 24: 123-4

 

Schroeder C, Tank J, Heusser K, Busjahn A, Diedrich A, Luft FC, Jordan J. Orthostatic tolerance is difficult to predict in recurrent syncope patients. Clin Auton Res 2011; 21: 37-45

 

Schwarz A, Modun D, Heusser K, Tank J, Gutzki FM, Mitschke A, Jordan J, Tsikas D. Stable-isotope dilution GC-MS approach for nitrite quantification in human whole blood, erythrocytes, and plasma using pentafluorobenzyl bromide derivatization: Nitrite distribution in human blood. J Chromatogr B Analyt Technol Biomed Life Sci 2011; 879: 1485-95

 

Haghikia A, Missol-Kolka E, Tsikas D, Venturini L, Brundiers S, Castoldi M, Muckenthaler MU, Eder M, Stapel B, Thum T, Haghikia A, Petrasch-Parwez E, Drexler H, Hilfiker-Kleiner D, Scherr M. Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes. Eur Heart J 2011; 32: 1287-97

 

Ritter B, Kilian P, Reboll MR, Resch K, DiStefano JK, Frank R, Beil W, Nourbakhsh M. Differential effects of multiplicity of infection on Helicobacter pylori-induced signaling pathways and interleukin-8 gene transcription. J Clin Immunol 2011; 31: 60-8

 

Tank J, Baevsky RM, Funtova II, Diedrich A, Slepchenkova IN, Jordan J. Orthostatic heart rate responses after prolonged space flights. Clin Auton Res 2011; 21: 121-4

 

 

 

 

 

Publikationen 2010

  

von Haehling S, Lainscak M, Doehner W, Ponikowski P, Rosano G, Jordan J, Rozentryt P, Rauchhaus M, Karpov R, Tkachuk V, Parfyonova Y, Zaritskey AY, Shlyakhto EV, Cleland JG, Anker SD. J Diabetes mellitus, cachexia and obesity in heart failure: rationale and design of the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF). Cachexia Sarcopenia Muscle 2010; 1: 187-194

  

Stichtenoth DO. Diabetic with lactose intolerance. Is there a drug without lactose? MMW Fortschr Med 2010; 152: 24

  

Dzamonja G, Tank J, Heusser K, Palada I, Valic Z, Bakovic D, Obad A, Ivancev V, Breskovic T, Diedrich A, Luft FC, Dujic Z, Jordan J. Glossopharyngeal insufflation induces cardioinhibitory syncope in apnea divers. Clin Auton Res 2010; 20: 381-4

 

Tank J, Heusser K, Diedrich A, Luft FC, Jordan J. A novel pharmacological approach to determining parasympathetic heart rate reserve in human subjects. Clin Pharmacol Ther 2010; 88: 630-3 

 

Schwedhelm E, Bierend A, Maas R, Trinks R, Kom GD, Tsikas D, Böger RH. Redox-Generated Isoprostanes are Associated with Residual Platelet Activity in Aspirin-Treated Patients with Stable Coronary Heart Disease. J Thromb Haemost 2010; 8: 2662-70

 

Scheffers IJ, Kroon AA, Schmidli J, Jordan J, Tordoir JJ, Mohaupt MG, Luft FC, Haller H, Menne J, Engeli S, Ceral J, Eckert S, Erglis A, Narkiewicz K, Philipp T, de Leeuw PW. Novel baroreflex activation therapy in resistant hypertension: results of a European multi-center feasibility study. J Am Coll Cardiol 2010; 56: 1254-8

 

Picksak G, Stichtenoth DO. Hepatitis A vaccination three days before departure to Eastern Europe? Med Monatsschr Pharm 2010; 33: 261-2

 

Tsikas D, Zoerner AA, Gutzki FM, Rossi R. On the mercapturic acid pathway of nitric oxide: is S-nitrosoglutathione present in the bile? Hepatology 2010;52: 1858-9; author reply 1859-60

 

Heusser K, Dzamonja G, Breskovic T, Steinback CD, Diedrich A, Tank J, Jordan J, Dujic Z. Sympathetic and cardiovascular responses to glossopharyngeal insufflation in trained apnea divers. J Appl Physiol 2010; 109: 1728-35

 

Jordan J. What rare autonomic disorders can teach us about human cardiovascular pharmacology. Hypertension 2010; 56: 811-3 

  

Tsikas D. Identifying and quantifying contaminants contributing to endogenous analytes in gas chromatography/mass spectrometry. Anal Chem 2010; 82: 7835-41

 

Thum T, Batkai S, Malinski PG, Becker T, Mevius I, Klempnauer J, Meyer HH, Frölich JC, Borlak J, Tsikas D. Measurement and diagnostic use of hepatic cytochrome P450 metabolism of oleic acid in liver disease. Liver Int 2010; 30: 1181-8

 

Krause P, Wätzig E, Acil H, König S, Unthan-Fechner K, Tsikas D, Probst I. Role of carbon monoxide and nitric oxide in adult rat hepatocytes proliferating in vitro: Effects of CAS 1609. Nitric Oxide 2010; 23: 220-6

 

Sato K, Urbano R, Yu C, Yamasaki F, Sato T, Jordan J, Robertson D, Diedrich A. The effect of donepezil treatment on cardiovascular mortality. Clin Pharmacol Ther 2010; 88: 335-8

 

Haufe S, Engeli S, Budziarek P, Utz W, Schulz-Menger J, Hermsdorf M, Wiesner S, Otto C, Haas V, de Greiff A, Luft FC, Boschmann M, Jordan J. Cardiorespiratory fitness and insulin sensitivity in overweight or obese subjects may be linked through intrahepatic lipid content. Diabetes 2010; 59: 1640-7

 

Picksak G, Stichtenoth DO. SSRI-associated bleeding risk. Med Monatsschr Pharm 2010; 33: 217-8

 

Foley JE, Jordan J. Weight neutrality with the DPP-4 inhibitor vildagliptin: mechanistic basis and clinical experience. Vascular Health and Risk Management 2010; 6: 541-8

 

Tsikas D, Chobanyan-Jürgens K. Quantification of Carbonate by Gas Chromatography-Mass Spectrometry. Anal Chem 2010; 82: 7897-905

 

Jordan J, Grassi G. Belly fat and resistant hypertension. J Hypertens 2010; 28: 1131-3

 

McHugh J, Keller NR, Appalsamy M, Thomas SA, Raj SR, Diedrich A, Biaggioni I, Jordan J, Robertson D. Portal osmopressor mechanism linked to transient receptor potential vanilloid 4 and blood pressure control. Hypertension 2010; 55: 1438-43

  

Thielecke F, Rahn G, Böhnke J, Adams F, Birkenfeld AL, Jordan J, Boschmann M. Epigallocatechin-3-gallate and postprandial fat oxidation in overweight/obese male volunteers: a pilot study. Eur J Clin Nutr 2010; 64: 704-13

  

Dreißigacker U, Wendt M, Wittke T, Tsikas D, Maassen N. Positive correlation between plasma nitrite and performance during high-intensive exercise but not oxidative stress in healthy men. Nitric Oxide 2010; 23: 128-35

  

Heusser K, Tank J, Engeli S, Diedrich A, Menne J, Eckert S, Peters T, Sweep FC, Haller H, Pichlmaier AM, Luft FC, Jordan J. Carotid baroreceptor stimulation, sympathetic activity, baroreflex function, and blood pressure in hypertensive patients. Hypertension 2010; 55: 619-26

 

Chaudhry  I, Jordan J, Cousin FR, Cavallaro R, Mostaza JM.  Management of physical health in schizophrenia: international insights. European Psychiatry 2010; 25 (Suppl 2): S37-S40

 

Jumpertz R, Wiesner T, Blüher M, Engeli S, Bátkai S, Wirtz H, Bosse-Henck A, Stumvoll M. Circulating Endocannabinoids and N-acyl-ethanolamides in Patients with Sleep Apnea - Specific Role of Oleoylethanolamide. Exp Clin Endocrinol Diabetes 2010; 118: 591-5

 

May M, Jordan J. Betablockade bei Adipositas-assoziierter Hypertonie: Ein zweischneidiges Schwert. Adipositas 2010; 4: 91-4

 

Schleinitz D, Carmienke S, Böttcher Y, Tönjes A, Berndt J, Klöting N, Enigk B, Müller I, Dietrich K, Breitfeld J, Scholz GH, Engeli S, Stumvoll M, Blüher M, Kovacs P. Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity. Pharmacogenomics 2010; 11: 693-702

 

Wiesner S, Birkenfeld AL, Engeli S, Haufe S, Brechtel L, Wein J, Hermsdorf M, Karnahl B, Berlan M, Lafontan M, Sweep FC, Luft FC, Jordan J. Neurohumoral and metabolic response to exercise in water. Horm Metab Res 2010; 42: 334-9

 

Boschmann M, Engeli S, Moro C, Luedtke A, Adams F, Gorzelniak K, Rahn G, Mähler A, Dobberstein K, Krüger A, Schmidt S, Spuler S, Luft FC, Smith SR, Schmidt HH, Jordan J. LMNA mutations, skeletal muscle lipid metabolism, and insulin resistance. J Clin Endocrinol Metab 2010; 95: 1634-43 

 

Tank J, Heusser K, Schroeder C, Luft FC, Jordan J. Autonomic failure in a HIV-infected patient. Clin Auton Res 2010; 20: 263-5

 

Tsikas D, Böhmer A, Mitschke A. Gas chromatography-mass spectrometry analysis of nitrite in biological fluids without derivatization. Anal Chem 2010; 82: 5384-90

 

Breskovic T, Ivancev V, Banic I, Jordan J, Dujic Z.  Peripheral chemoreflex sensitivity and sympathetic nerve activity are normal in apnea divers during training season.  Autonomic Neuroscience 2010; 154: 42-7

 

De Rop C, Picksak G, Stichtenoth DO. Gingival hyperplasia. Med Monatsschr Pharm 2010; 33: 23-4

 

Tsikas D, Wolf A, Mitschke A, Gutzki FM, Will W, Bader M. GC-MS determination of creatinine in human biological fluids as pentafluorobenzyl derivative in clinical studies and biomonitoring: Inter-laboratory comparison in urine with Jaffé, HPLC and enzymatic assays. J Chromatogr B Analyt Technol Biomed Life Sci. 2010; 878: 2582-92

 

Tsikas D. Measurement of nitrotyrosine in plasma by immunoassays is fraught with danger: commercial availability is no guarantee of analytical reliability. Clin Chem Lab Med 2010; 48: 141-3

 

Nachtigall J, Schulz D, Beil W, Süssmuth RD, Fiedler HP. Aranciamycin anhydride, a new anthracycline-type antibiotic isolated from Streptomyces sp. Tü 6384(*). J Antibiot (Tokyo) 2010; 63: 397-9

 

Tsikas D, Schwarz A, Stichtenoth DO. Simultaneous measurement of [15N]nitrate and [15N]nitrite enrichment and concentration in urine by gas chromatography mass spectrometry as pentafluorobenzyl derivatives. Anal Chem 2010; 82: 2585-7

 

Breskovic T, Valic Z, Lipp A, Heusser K, Ivancev V, Tank J, Dzamonja G, Jordan J, Shoemaker JK, Eterovic D, Dujic Z. Peripheral chemoreflex regulation of sympathetic vasomotor tone in apnea divers. Clin Auton Res 2010; 20: 57-63

 

Tsikas D. Quantitative analysis of biomarkers, drugs and toxins in biological samples by immunoaffinity chromatography coupled to mass spectrometry or tandem mass spectrometry: A focused review of recent applications. J Chromatogr B Analyt Technol Biomed Life Sci 2010; 878: 133-48

 

Straznicky N, Grassi G, Esler M, Lambert G, Dixon J, Lambert E, Jordan J, Schlaich M; for the European Society of Hypertension Working Group on Obesity, the Australian, New Zealand Obesity Society. European Society of Hypertension Working Group on Obesity antihypertensive effects of weight loss: myth or reality? J Hypertens 2010; 28: 637-43

 

Haufe S, Engeli S, Budziarek P, Utz W, Schulz-Menger J, Hermsdorf M, Wiesner S, Otto C, Fuhrmann JC, Luft FC, Boschmann M, Jordan J. Determinants of exercise-induced fat oxidation in obese women and men. Horm Metab Res 2010; 42: 215-21

 

Wiesner S, Haufe S, Engeli S, Mutschler H, Haas U, Luft FC, Jordan J. Influences of normobaric hypoxia training on physical fitness and metabolic risk markers in overweight to obese subjects. Obesity (Silver Spring) 2010; 18: 116-20

 

Dreiβigacker U, Suchy MT, Maassen N, Tsikas D. Human plasma concentrations of malondialdehyde (MDA) and the F(2)-isoprostane 15(S)-8-iso-PGF(2alpha) may be markedly compromised by hemolysis: Evidence by GC-MS/MS and potential analytical and biological ramifications. Clin Biochem 2010; 43: 159-67

 

Tsikas D, Mitschke A, Gutzki FM, Engeli S, Jordan J. Evidence by gas chromatography-mass spectrometry of ex vivo nitrite and nitrate formation from air nitrogen oxides in human plasma, serum, and urine samples. Anal Biochem 2010; 397: 126-8

 

Tsikas D, Engeli S, Beckmann B, Jordan J. Asymmetric dimethylarginine (ADMA) is present in plasma proteins of healthy subjects at the low nmol-per-g-level. Nitric Oxide 2010; 22: 316-7

 

 

 

 

Publikationen 2009 

 

Giustarini D, Dalle-Donne I, Tsikas D, Rossi R. Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers. Crit Rev Clin Lab Sci 2009; 46: 241-81

 

Tsikas D. Reliable quantification of endogenous free 3-nitrotyrosine in human plasma by GC–ECD or GC–MS in health and disease? Chromatographia 2009; 70: 1767-8

 

Hunt RH, Lanas A, Stichtenoth DO, Scarpignato C. Myths and facts in the use of anti-inflammatory drugs. Ann Med 2009; 41: 423-37

 

Tsikas D, Beckmann B. Albumin from human serum does not contain asymmetric dimethylarginine (ADMA). Clin Biochem 2009; 42: 1739-40

 

Dujic Z, Uglesic L, Breskovic T, Valic Z, Heusser K, Marinovic J, Ljubkovic M, Palada I. Involuntary breathing movements improve cerebral oxygenation during apnea struggle phase in elite divers. J Appl Physiol 2009; 107: 1840-6

 

Birkenfeld AL, Jordan J, Hofmann U, Busjahn A, Franke G, Krüger N, Igel S, Mürdter T, Drescher S, Shi S, Engeli S, Schwab M, Eichelbaum M, Luft FC, Fromm MF. Genetic influences on the pharmacokinetics of orally and intravenously administered digoxin as exhibited by monozygotic twins. Clin Pharmacol Ther 2009; 86: 605-8

 

Pham VV, Stichtenoth DO, Tsikas D. Nitrite correlates with 3-nitrotyrosine but not with the F(2)-isoprostane 15(S)-8-iso-PGF(2alpha) in urine of rheumatic patients. Nitric Oxide 2009 21: 210-5

 

Schroeder C, Batkai S, Engeli S, Tank J, Diedrich A, Luft FC, Jordan J. Circulating endocannabinoid concentrations during orthostatic stress. Clin Auton Res 2009; 19: 343-6

 

Tsikas D, Zoerner AA, Mitschke A, Gutzki FM. Nitro-fatty acids occur in human plasma in the picomolar range: a targeted nitro-lipidomics GC-MS/MS study. Lipids 2009; 44: 855-65

 

Michaelsen JT, Dehnert S, Giustarini D, Beckmann B, Tsikas D. HPLC analysis of human erythrocytic glutathione forms using OPA and N-acetyl-cysteine ethyl ester: evidence for nitrite-induced GSH oxidation to GSSG. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 3405-17

 

Tsikas D, Dehnert S, Urban K, Surdacki A, Meyer HH. GC-MS analysis of S-nitrosothiols after conversion to S-nitroso-N-acetyl cysteine ethyl ester and in-injector nitrosation of ethyl acetate. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 3442-55

 

Martens-Lobenhoffer J, Schwedhelm E, Tsikas D. Quantification of arginine and its mono- and dimethylated analogs NMMA, ADMA and SDMA in biological fluids by LC-MS/MS: Is LC superfluous? J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 3261-6

 

Magné J, Huneau JF, Tsikas D, Delemasure S, Rochette L, Tomé D, Mariotti F. Rapeseed Protein in a High-Fat Mixed Meal Alleviates Postprandial Systemic and Vascular Oxidative Stress and Prevents Vascular Endothelial Dysfunction in Healthy Rats. J Nutr 2009; 139: 1660-6

 

Tsikas D. Comments on "Determination of S-nitrosoglutathione and other nitrosothiols by p-hydroxymercurybenzoate derivatization and reverse phase chromatography coupled with chemical vapor generation atomic fluorescence detection" by Bramanti et al. Talanta 2009; 79: 552-3

 

Andresen H, Bingel U, Streichert T, Schmoldt A, Zoerner AA, Tsikas D, Just I. Severe glycerol intoxication after Menière's disease diagnostic--case report and overview of kinetic data. Clin Toxicol 2009; 47: 312-6

 

de Vries DK, Lindeman JH, Tsikas D, de Heer E, Roos A, de Fijter JW, Baranski AG, van Pelt J, Schaapherder AF. Early Renal Ischemia-Reperfusion Injury in Humans Is Dominated by IL-6 Release from the Allograft. Am J Transplant 2009; 9: 1574-84

 

Tsikas D, Rossi R. Letter by Tsikas and Rossi regarding article, "Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction". Circulation 2009; 119: e531

 

Zoerner AA, Gutzki FM, Suchy MT, Beckmann B, Engeli S, Jordan J, Tsikas D. Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 2909-23

 

Rossi R, Tsikas D. S-Nitrosothiols in blood: does photosensitivity explain a 4-order-of-magnitude concentration range? Clin Chem 2009; 55: 1036-8

 

Bader M, Rosenberger W, Gutzki FM, Tsikas D. Quantification of N-(3-chloro-2-hydroxypropyl)valine in human haemoglobin as a biomarker of epichlorohydrin exposure by gas chromatography-tandem mass spectrometry with stable-isotope dilution. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 1402-15

 

Busjahn CA, Schulz-Menger J, Abdel-Aty H, Rudolph A, Jordan J, Luft FC, Busjahn A. Heritability of left ventricular and papillary muscle heart size: a twin study with cardiac magnetic resonance imaging. Eur Heart J 2009; Apr 30. [Epub ahead of print]

 

Heusser K, Dzamonja G, Tank J, Palada I, Valic Z, Bakovic D, Obad A, Ivancev V, Breskovic T, Diedrich A, Joyner MJ, Luft FC, Jordan J, Dujic Z.  Cardiovascular regulation during apnea in elite divers. Hypertension 2009;  53: 719-24

 

Kielstein JT, Hesse G, Bahr MJ, Tsikas D, Terkamp C, Martens-Lobenhoffer J, Manns MP, Haller H, Panning B, Bode-Böger SM, Gebel M. Procedure-related pulmonary hypertension in patients with hepatocellular carcinoma undergoing percutaneous ethanol injection--role of ethanol, hemolysis, asymmetric dimethylarginine, and the nitric oxide system. Crit Care Med 2009; 37: 1483-5

 

Becker CDK, Stichtenoth DO, Wichmann MG, Schaefer C, Szinicz L. Blood Donors on Medication – an Approach to Minimize Drug Burden for Recipients of Blood Products and to Limit Deferral of Donors. Transfus Med Hemother 2009; 36: 107-113

 

Janke J, Engeli S, Gorzelniak K, Luft FC, Jordan J. Compounds used for „injection lipolysis“ destroy adipocytes and other cells found in adipose tissue. Obesity Facts 2009; 2: 36-39

 

Picksak G, Stichtenoth DO. Lactose-containing tablets for patients with lactose intolerance? Med Monatsschr Pharm 2009; 32: 27-8

 

Krausse-Opatz B, Wittkop U, Gutzki FM, Schmidt C, Jürgens-Saathoff B, Meier S, Beckmann B, Takikawa O, Morgan MA, Tsikas D, Stichtenoth DO, Wagner AD, Zeidler H, Köhler L. Free iron ions decrease indoleamine 2,3-dioxygenase expression and reduce IFNgamma-induced inhibition of Chlamydia trachomatis infection. Microb Pathog 2009; 46: 289-97

 

Tsikas D. A proposal for comparing methods of quantitative analysis of endogenous compounds in biological systems by using the relative lower limit of quantification (rLLOQ). J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 2244-51

 

Warnecke A, Luessen P, Sandmann J, Ikic M, Rossa S, Gutzki FM, Stichtenoth DO, Tsikas D. Application of a stable-isotope dilution technique to study the pharmacokinetics of human (15)N-labelled S-nitrosoalbumin in the rat: Possible mechanistic and biological implications. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 1375-87

 

Goncalves AC, Tank J, Diedrich A, Hilzendeger A, Plehm R, Bader M, Luft FC, Jordan J, Gross V. Diabetic hypertensive leptin receptor-deficient db/db mice develop cardioregulatory autonomic dysfunction. Hypertension 2009;53: 387-92

 

Tsikas D. De novo synthesis of trideuteromethyl esters of amino acids for use in GC-MS and GC-tandem MS exemplified for ADMA in human plasma and urine: Standardization, validation, comparison and proof of evidence for their aptitude as internal standards. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 2308-20

 

Schlaich MP, Grassi G, Lambert GW, Straznicky N, Esler MD, Dixon J, Lambert EA, Redon J, Narkiewicz K, Jordan J. European Society of Hypertension Working Group on Obesity Obesity-induced hypertension and target organ damage: current knowledge and future directions. J Hypertens 2009; 27: 207-211

 

Tsikas D, Zoerner A, Mitschke A, Homsi Y, Gutzki FM, Jordan J. Specific GC-MS/MS stable-isotope dilution methodology for free 9- and 10-nitro-oleic acid in human plasma challenges previous LC-MS/MS reports. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 2895-908

 

Gratze P, Boschmann M, Dechend R, Qadri F, Malchow J, Graeske S, Engeli S, Janke J, Springer J, Contrepas A, Plehm R, Klaus S, Nguyen G, Luft FC, Muller DN. Energy Metabolism in Human Renin-Gene Transgenic Rats. Does Renin Contribute to Obesity? Hypertension 2009; 53: 516-523

 

Schupp M, Lefterova MI, Janke J, Leitner K, Cristancho AG, Mullican SE, Qatanani M, Szwergold N, Steger DJ, Curtin JC, Kim RJ, Suh M, Albert MR, Engeli S, Gudas LJ, Lazar MA. Retinol saturase promotes adipogenesis and is downregulated in obesity. Proc Natl Acad Sci USA 2009; 106: 1105-10

 

Bernateck M, Karst M, Eberhard S, Vivell W, Fischer MJ, Stichtenoth DO. Placebo therapy: Analysis of extent and expectations in a tertiary referral center. Schmerz 2009; 23: 47-53

  

Becker T, Mevius I, de Vries DK, et al. The l-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: Biological and analytical ramifications. Nitric Oxide 2009; 20: 61-7

 

Schroeder C, Heusser K, Tank J, Diedrich A, Luft FC, Jordan J. The Valsalva maneuver: screening for drug-induced baroreflex dysfunction. Clin Auton Res 2009; 19: 32-8.

 

Kressel G, Trunz B, Bub A, Hülsmann O, Wolters M, Lichtinghagen R, Stichtenoth DO, Hahn A. Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk. Atherosclerosis 2009; 202: 263-71

 

Tsikas D, Hohlfeld JM. On the importance of the use of proper approaches for comparison of analytical methods for serum nitrate and for evaluation of reference concentrations. Clin Biochem 2009; 42: 1200-1

 

Frank H, Heusser K, Geiger H, Fahlbusch R, Naraghi R, Schobel HP. Temporary Reduction of Blood Pressure and Sympathetic Nerve Activity in Hypertensive Patients After Microvascular Decompression. Stroke 2009; 40: 47-51.

 

Boschmann M, Engeli S, Dobberstein K, Budziarek P, Strauss A, Boehnke J, Sweep FC, Luft FC, He Y, Foley JE, Jordan J. Dipeptidyl-Peptidase-IV Inhibition Augments Postprandial Lipid Mobilization and Oxidation in Type 2 Diabetic Patients. J Clin Endocrinol Metab 2009; 94: 846-852