Publikationen des Instituts

Publikationen 2007 und 2006

Lucke T, Kanzelmeyer N, Kemper MJ, Tsikas D, Das AM. Developmental changes in the L-arginine/nitric oxide pathway from infancy to adulthood: plasma asymmetric dimethylarginine levels decrease with age. Clin Chem Lab Med 2007 Sep 24; [Epub ahead of print]

Chobanyan K, Thum T, Suchy MT, Zhu B, Mitschke A, Gutzki FM, Beckmann B, Stichtenoth DO, Tsikas D. GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): Evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in humans. J Chromatogr B Analyt Technol Biomed Life Sci. 2007; 858: 32-41.

Picksak G, Stichtenoth DO. Splitting of tablets: small pieces a risk. Med Monatsschr Pharm 2007; 30: 340-2.

Kielstein A, Tsikas D, Galloway GP, Mendelson JE. Asymmetric dimethylarginine (ADMA)--a modulator of nociception in opiate tolerance and addiction? Nitric Oxide 2007; 17: 55-9.

Meyer GK, Neetz A, Brandes G, Tsikas D, Butterfield JH, Just I, Gerhard R. Clostridium difficile toxins A and B directly stimulate human mast cells. Infect Immun 2007; 75: 3868-76.

Thum T, Fleissner F, Klink I, Tsikas D, Jakob M, Bauersachs J, Stichtenoth DO. Growth hormone treatment improves markers of systemic nitric oxide bioavailability via insulin-like growth factor-1. J Clin Endocrinol Metab. 2007 Aug 28; [Epub ahead of print]

Chobanyan K, Mitschke A, Gutzki FM, Stichtenoth DO, Tsikas D. Accurate quantification of dimethylamine (DMA) in human plasma and serum by GC-MS and GC-tandem MS as pentafluorobenzamide derivative in the positive-ion chemical ionization mode. J Chromatogr B Analyt Technol Biomed Life Sci 2007; 851: 240-9

Picksak G, Stichtenoth DO. Aerosol administration - appropriate treatment for asthma in a "recovered alcoholic? Med Monatsschr Pharm 2007; 30: 187-9

Mitschke A, Gutzki FM, Tsikas D. 9- and 10-Nitro-oleic acid do not interfere with the GC-MS quantitative determination of nitrite and nitrate in biological fluids when measured as their pentafluorobenzyl derivatives. J Chromatogr B Analyt Technol Biomed Life Sci 2007; 851: 287-91.

Thum T, Fraccarollo D, Schultheiss M, Froese S, Galuppo P, Widder JD, Tsikas D, Ertl G, Bauersachs J. Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes. Diabetes 2007; 56: 666-74

Tsikas D. Analysis of the l-arginine/NO pathway. J Chromatogr B Analyt Technol Biomed Life Sci 2007 Feb 20; [Epub ahead of print]

Thum T, Hoeber S, Froese S, Klink I, Stichtenoth DO, Galuppo P, Jakob M, Tsikas D, Anker SD, Poole-Wilson PA, Borlak J, Ertl G, Bauersachs J. Age-Dependent Impairment of Endothelial Progenitor Cells is Corrected by Growth Hormone Mediated Increase of Insulin-Like Growth Factor-1. Circ Res 2007; 100: 434-43

Picksak G, Stichtenoth DO. Methylphenidat (Concerta®) und Leistungsradsport? Arzneimitteltherapie 2007; 25: 63-65.

Schmitt B, Wolters M, Kressel G, Hulsmann O, Strohle A, Kuhn-Velten WN, Lichtinghagen R, Bub A, Barth SW, Stichtenoth DO, Hahn A. Effects of combined supplementation with B vitamins and antioxidants on plasma levels of asymmetric dimethylarginine (ADMA) in subjects with elevated risk for cardiovascular disease. Atherosclerosis 2007; 193: 168-76

Tsikas D, Thum T, Becker T, Pham VV, Chobanyan K, Mitschke A, Beckmann B, Gutzki FM, Bauersachs J, Stichtenoth DO. Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease. J Chromatogr B Analyt Technol Biomed Life Sci 2007; 851: 229-39

Tsikas D. Analysis of nitrite and nitrate in biological fluids by assays based on the Griess reaction: appraisal of the Griess reaction in the L-arginine/nitric oxide area of research.
J Chromatogr B Analyt Technol Biomed Life Sci 2007; 851: 51-70.

Tsikas D. Vascular NO: from bench to bedside. Eur J Clin Pharmacol 2006; 62 (Suppl 13): 3

Tsikas D, Gutzki FM, Stichtenoth DO. Circulating and excretory nitrite and nitrate as indicators of nitric oxide synthesis in humans: methods of analysis. Eur J Clin Pharmacol 2006; 62: 51-59

Lenzen H, Tsikas D, Böger DH. Asymmetric dimethylarginine (ADMA) and the risk for coronary Asymmetric dimethylarginine (ADMA) and the risk for coronary heart disease: the multicenter CARDIAC study. Eur J Clin Pharmacol 2006; 62: 45–49

Kielstein JT, Tsikas D, Fliser D. Effects of asymmetric dimethylarginine (ADMA) infusion in humans. Eur J Clin Pharmacol 2006; 62: 39-44

Thum T, Fraccarollo D, Galuppo P, Tsikas D, Frantz S, Ertl G, Bauernsachs J. Bone marrow molecular alterations after myocardial infarction: Impact on endothelial progenitor cell. Cardiovascular Research 2006; 70: 50-60

Mang B, Wolters M, Schmitt B, Kelb K, Lichtenhagen R, Stichtenoth D O, Hahn A. Effects of a cinnamon extract on plasma glucose, HbAlc, and serum lipids in diabetes mellitus type 2. European Journal of Clinical Investigation 2006; 36: 340-344

Brabant T, Stichtenoth DO. Die medikamentöse Therapie der Rheumatoiden Arthritis. Geriatrie Journal 2006; 2: 23-28

Templin C, Kotlarz D, Marquart F, Faulhaber J, Brendecke V, Schäfer A, Tsikas D, Bonda T, Hilfiker-Kleiner D, Ohl L, Naim HY, Förster R, Drexler H, Limbourg FP. Transcoronary delivery of bone marrow cells to the infarcted murine myocardium. Basic Res Cardiol 2006; 101: 301-310

Goette A, Hammwohner M, Dierkes J, Lachmuth J, Frölich JC, Klein H, Bode-Böger SM. Aortic thrombus and pulmonary embolism in a patient with hyperhomocysteinemia. Nature Clinical Practice Cardiovascular Medicine 2006; 3: 396-399

Lücke T, Tsikas D, Kanzelmeyer NK, Boerkoel CF, Clewing JM, Vaske B, Ehrich JHH, Das AM. Vaso-occlusion in Schimke-immuno-osseous Dysplasia: Is the NO Pathway Involved? Horm Metab Res 2006; 38: 678-682

Lücke T, Tsikas D, Kanzelmeyer N, Vaske B, Das AM. Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine in citrullinemia. Metabolism 2006; 55: 1599-1603