Publikationen 2011
Nugraha B, Karst M, Engeli S, Gutenbrunner C. Brain-derived neurotrophic factor and exercise in fibromyalgia syndrome patients: a mini review. Rheumatol Int 2011; Dec 31 [Epub ahead of print]
Schroeder C, Stabroth C, Luft FC, Jordan J. Adrenergic Cardiovascular Control Before and After Removal of Stimulatory α-1 Adrenoreceptor Antibodies. Hypertension 2011 Dec 27 [Epub ahead of print]
Böhmer A, Mitschke A, Reib A, Gutzki FM, Tsikas D. (18)O-Labeled nitrous acid and nitrite: Synthesis, characterization, and oxyhemoglobin-catalyzed oxidation to (18)O-labeled nitrate. Anal Biochem 2011 Dec 9 [Epub ahead of print]
Khalil AA, Tsikas D, Akolekar R, Jordan J, Nicolaides KH. Asymmetric dimethylarginine, arginine and homoarginine at 11-13 weeks' gestation and preeclampsia: a case-control study. J Hum Hypertens 2011 Dec 8 [Epub ahead of print]
Picksak G, Stichtenoth DO, Reuter J. Therapy of a common otitis media in the infancy. Med Monatsschr Pharm 2011; 34: 430-2
Kupfahl C, Tsikas D, Niemann J, Geginat G, Hof H. Production of prostaglandins, isoprostanes and thromboxane by Aspergillus fumigatus: Identification by gas chromatography-tandem mass spectrometry and quantification by enzyme immunoassay. Mol Immunol 2011 Nov 24 [Epub ahead of print]
von Leitner EC, Klinke A, Atzler D, Slocum JL, Lund N, Kielstein JT, Maas R, Schmidt-Haupt R, Pekarova M, Hellwinkel O, Tsikas D, D'Alecy LG, Lau D, Willems S, Kubala L, Ehmke H, Meinertz T, Blankenberg S, Schwedhelm E, Gadegbeku CA, Böger RH, Baldus S, Sydow K. Pathogenic Cycle Between the Endogenous Nitric Oxide Synthase Inhibitor Asymmetrical Dimethylarginine and the Leukocyte-Derived Hemoprotein Myeloperoxidase. Circulation 2011; 124: 2735-45
Rakers C, Zoerner AA, Engeli S, Batkai S, Jordan J, Tsikas D. Stable isotope liquid chromatography-tandem mass spectrometry assay for fatty acid amide hydrolase activity. Anal Biochem 2011 Nov 13 [Epub ahead of print]
Chobanyan-Jürgens K, Fuchs AJ, Tsikas D, Kanzelmeyer N, Das AM, Illsinger S, Vaske B, Jordan J, Lücke T. Increased asymmetric dimethylarginine (ADMA) dimethylaminohydrolase (DDAH) activity in childhood hypercholesterolemia type II. Amino Acids 2011 Nov 11 [Epub ahead of print]
Haufe S, Utz W, Engeli S, Kast P, Böhnke J, Pofahl M, Traber J, Haas V, Hermsdorf M, Mähler A, Busjahn A, Wiesner S, Otto C, Mehling H, Luft FC, Boschmann M, Schulz-Menger J, Jordan J. Left Ventricular Mass and Function With Reduced-Fat or Reduced-Carbohydrate Hypocaloric Diets in Overweight and Obese Subjects. Hypertension 2011 Nov 7 [Epub ahead of print]
Schroeder C, Tank J, Heusser K, Diedrich A, Luft FC, Jordan J. Physiological phenomenology of neurally-mediated syncope with management implications. PLoS One 2011; 6: e26489. Epub 2011 Oct 25
May M, Gueler F, Barg-Hock H, Heiringhoff KH, Engeli S, Heusser K, Diedrich A, Brandt A, Strassburg CP, Tank J, Sweep FC, Jordan J. Liver afferents contribute to water drinking-induced sympathetic activation in human subjects: a clinical trial. PLoS One 2011; 6: e25898. Epub 2011 Oct 7
Marinovic J, Ljubkovic M, Breskovic T, Gunjaca G, Obad A, Modun D, Bilopavlovic N, Tsikas D, Dujic Z. Effects of successive air and nitrox dives on human vascular function. Eur J Appl Physiol 2011 Oct 1 [Epub ahead of print]
Zoerner AA, Gutzki FM, Batkai S, May M, Rakers C, Engeli S, Jordan J, Tsikas D. Quantification of endocannabinoids in biological systems by chromatography and mass spectrometry: A comprehensive review from an analytical and biological perspective. Biochim Biophys Acta 2011; 1811: 706-23
Giustarini D, Tsikas D, Rossi R. Study of the effect of thiols on the vasodilatory potency of S-nitrosothiols by using a modified aortic ring assay. Toxicol Appl Pharmacol 2011; 256: 95-102
Janina Willers, Sabine Fasse, Nils Putschky, Henning Zeidler, Hans-Georg Pott, Michael Bernateck, Winfried Demary, Reinhard Hein5 Vu Vi Pham, Rainer Stange, Bernhard Uehleke, Heike Franziska Weidemann, Guido Hoese, Ralf Lichtinghagen, Andreas Hahn. Combined Add-on Supplementation of Omega-3 Fatty Acids, Vitamin E, Vitamin A, Copper, and Selenium in Rheumatoid Arthritis. Food and Nutrition Sciences 2011; 2: 714-723
Haas V, Engeli S, Hofmann T, Riedl A, Haufe S, Kast P, Wiesner S, Böhnke J, Jordan J, Boschmann M. Variations in truncal body circumferences affect fat mass quantification with bioimpedance analysis. Eur J Clin Nutr 2011 Sep 7 [Epub ahead of print]
Schroeder C, Jordan J. Norepinephrine uptake mechanisms in cardiovascular disease deserve our attention. J Cardiovasc Pharmacol 2011; 58: 406-8
Chobanyan-Jürgens K, Pham VV, Stichtenoth DO, Tsikas D. Elevated dimethylarginine dimethylaminohydrolase (DDAH) activity in rheumatoid arthritis and spondyloarthritis. Nitric Oxide 2011; 25: 436-8
da Costa Goncalves AC, Fontes MA, Klussmann E, Qadri F, Janke J, Gollasch M, Schleifenbaum J, Müller D, Jordan J, Tank J, Luft FC, Gross V. Spinophilin regulates central angiotensin II-mediated effect on blood pressure. J Mol Med 2011; 89: 1219-29
Tsikas D, Engeli S, Tank J, Stichtenoth DO, Jordan J. Comment on: Ott et al. Reduction in Basal Nitric Oxide Activity Causes Albuminuria. Diabetes 2011; 60: 572-576. Diabetes 2011; 60(8): e21
Chobanyan-Jürgens K, Pham VV, Stichtenoth DO, Tsikas D. Asymmetrical dimethylarginine, oxidative stress, and atherosclerosis. Hypertension 2011; 58: 184-5
Stichtenoth D. Medikationsfehler: Patientensicherheit und Risikomanagement. In: Von Eiff, W (Hrsg.): Patientenorientierte Arzneimittelversorgung - Sicherheit und Wirtschaftlichkeit des Arzneimittelmanagements. Georg Thieme Verlag, Stuttgart 2011: 64-68
Tsikas D, Zoerner AA, Jordan J. Oxidized and nitrated oleic acid in biological systems: Analysis by GC-MS/MS and LC-MS/MS, and biological significance. Biochim Biophys Acta 2011; 1811: 694-705
Zoerner AA, Batkai S, Suchy MT, Gutzki FM, Engeli S, Jordan J, Tsikas D. Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: Minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. J Chromatogr B Analyt Technol Biomed Life Sci 2011 Jun 22 [Epub ahead of print]
Utz W, Engeli S, Haufe S, Kast P, Hermsdorf M, Wiesner S, Pofahl M, Traber J, Luft FC, Boschmann M, Schulz-Menger J, Jordan J. Myocardial steatosis, cardiac remodelling and fitness in insulin-sensitive and insulin-resistant obese women. Heart 2011; 97: 1585-9
Trettin A, Zoerner AA, Böhmer A, Gutzki FM, Stichtenoth DO, Jordan J, Tsikas D. Quantification of acetaminophen (paracetamol) in human plasma and urine by stable isotope-dilution GC-MS and GC-MS/MS as pentafluorobenzyl ether derivative. J Chromatogr B Analyt Technol Biomed Life Sci 2011; 879: 2274-80
Zoerner AA, Stichtenoth DO, Engeli S, Batkai S, Winkler C, Schaumann F, Janke J, Holz O, Krug N, Tsikas D, Jordan J, Hohlfeld JM. Allergen Challenge Increases Anandamide in Bronchoalveolar Fluid of Patients With Allergic Asthma. Clin Pharmacol Ther 2011; 90: 388-91
Reuter J, Jordan J. The dismal fat, kidney and brain connection: what to do? Hypertens Res 2011; 34: 906-8
Voigt C, Donat CK, Hartig W, Förschler A, Skardelly M, Stichtenoth D, Arendt T, Meixensberger J, Schuhmann MU. Effect of leukotriene inhibitors on evolution of experimental brain contusions. Neuropathol Appl Neurobiol 2011 Aug 11 [Epub ahead of print]
Haufe S, Jordan J. Obesity can break your heart and more so when you are a woman. J Hypertens 2011; 29: 1295-7
Herse F, Fain JN, Janke J, Engeli S, Kuhn C, Frey N, Weich HA, Bergmann A, Kappert K, Karumanchi SA, Luft FC, Muller DN, Staff AC, Dechend R. Adipose tissue-derived soluble fms-like tyrosine kinase 1 is an obesity-relevant endogenous paracrine adipokine. Hypertension 2011; 58: 37-42
Batinic T, Utz W, Breskovic T, Jordan J, Schulz-Menger J, Jankovic S, Dujic Z, Tank J. Cardiac Magnetic Resonance Imaging during Pulmonary Hyperinflation in Apnea Divers. Med Sci Sports Exerc 2011; 43: 2095-101
Johnston A, Asmar R, Dahlöf B, Hill K, Jones DA, Jordan J, Livingston M, Macgregor G, Sobanja M, Stafylas P, Rosei EA, Zamorano J. Generic and therapeutic substitution: a viewpoint on achieving best practice in Europe. Br J Clin Pharmacol 2011; 72: 727-730
Kanzelmeyer N, Tsikas D, Chobanyan-Jürgens K, Beckmann B, Vaske B, Illsinger S, Das AM, Lücke T. Asymmetric dimethylarginine in children with homocystinuria or phenylketonuria. Amino Acids 2011 Apr 7. [Epub ahead of print]
Jordan J. Diagnostik und Therapie des Baroreflexversagens. Klinische Neurophysiologie 2011; 42: 92-96
Tank J, Heusser K, Diedrich A, Hering D, Luft FC, Busjahn A, Aydin A, Limon J, Narkiewicz K, Jordan J. Beta-2 adrenoreceptor gene polymorphisms and sympathetic outflow in humans. Clin Auton Res 2011; 21: 333-8
Haufe S, Engeli S, Kast P, Böhnke J, Utz W, Haas V, Hermsdorf M, Mähler A, Wiesner S, Birkenfeld AL, Sell H, Otto C, Mehling H, Luft FC, Eckel J, Schulz-Menger J, Boschmann M, Jordan J. Randomized comparison of reduced fat and reduced carbohydrate hypocaloric diets on intrahepatic fat in overweight and obese human subjects. Hepatology 2011; 53: 1504-14
Engeli S, Tsikas D, Lehmann AC, Böhnke J, Haas V, Strauß A, Janke J, Gorzelniak K, Luft FC, Jordan J. Influence of dietary fat ingestion on asymmetrical dimethylarginine in lean and obese human subjects. Nutr Metab Cardiovasc Dis 2011 Mar 18 [Epub ahead of print]
Tsikas D, Beckmann B, Gutzki FM, Jordan J. Simultaneous gas chromatography-tandem mass spectrometry quantification of symmetric and asymmetric dimethylarginine in human urine. Anal Biochem 2011; 413: 60-2
Jordan J, Schlaich M, Redon J, Narkiewicz K, Luft FC, Grassi G, Dixon J, Lambert G, Engeli S; European Society of Hypertension Working Group on Obesity; Australian and New Zealand Obesity Society. European Society of Hypertension Working Group on Obesity: obesity drugs and cardiovascular outcomes. J Hypertens 2011; 29: 189-93
Tank J, Biller H, Heusser K, Holz O, Diedrich A, Framke T, Koch A, Grosshennig A, Koch W, Krug N, Jordan J, Hohlfeld JM. Effect of acute ozone induced airway inflammation on human sympathetic nerve traffic: a randomized, placebo controlled, crossover study. PLoS One 2011; 6: e18737
Lechner SG, Markworth S, Poole K, Smith ES, Lapatsina L, Frahm S, May M, Pischke S, Suzuki M, Ibañez-Tallon I, Luft FC, Jordan J, Lewin GR. The molecular and cellular identity of peripheral osmoreceptors. Neuron 2011; 69: 332-44
Tsikas D, Trettin A, Zörner AA, Gutzki FM. In-source formation of N-acetyl-p-benzoquinone imine (NAPQI), the putatively toxic acetaminophen (paracetamol) metabolite, after derivatization with pentafluorobenzyl bromide and GC-ECNICI-MS analysis. J Chromatogr B Analyt Technol Biomed Life Sci 2011; 879: 1476-84
Schmidt LM, Belvisi MG, Bode KA, Bauer J, Schmidt C, Suchy MT, Tsikas D, Scheuerer J, Lasitschka F, Gröne HJ, Dalpke AH. Bronchial epithelial cell-derived prostaglandin E2 dampens the reactivity of dendritic cells. J Immunol 2011; 186: 2095-2105
Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS, Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA, Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz I, Schondorff R, Stewart JM, van Dijk JG. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res 2011; 21: 69-72
Kirchner GI, Beil W, Bleck JS, Manns MP, Wagner S. Prevalence of Helicobacter pylori and occurrence of gastroduodenal lesions in patients with liver cirrhosis. Int J Clin Exp Med 2011; 4: 26-31
Jordan J, Grassi G. Run kidney, run: lifestyle interventions in the prevention of kidney disease. J Hypertens 2011; 29: 437-9
Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS, Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA, Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz IJ, Schondorf R, Stewart JM, van Dijk JG. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Auton Neurosci 2011; 161: 46-8
Bergmann MW, Haufe S, von Knobelsdorff-Brenkenhoff F, Mehling H, Waßmuth R, Münch I, Busjahn A, Schulz-Menger J, Jordan J, Luft FC, Dietz R. A pilot study of chronic, low-dose epoetin-{beta} following percutaneous coronary intervention suggests safety, feasibility, and efficacy in patients with symptomatic ischaemic heart failure. Eur J Heart Fail 2011; 13: 560-568
Birkenfeld AL, Adams F, Schroeder C, Engeli S, Jordan J. Metabolic actions could confound advantageous effects of combined angiotensin II receptor and neprilysin inhibition. Hypertension 2011; 57: e4-5
Tsikas D, Sandmann J, Beckmann B. Analysis of NO and its metabolites by mass spectrometry. Comment on 'Detection of nitric oxide in tissue samples by ESI-MS' by Z. Shen, A. Webster, K. J. Welham, C. E. Dyer, J. Greenman and S. J. Haswell. Analyst 2011; 136: 407-10
May M, Jordan J. The osmopressor response to water drinking. Am J Physiol Regul Integr Comp Physiol 2011; 300: R40-6
Tsikas D. GC-MS and HPLC methods for peroxynitrite (ONOO- and O15NOO-) analysis: a study on stability, decomposition to nitrite and nitrate, laboratory synthesis, and formation of peroxynitrite from S-nitrosoglutathione (GSNO) and KO2. Analyst 2011; 136: 979-87
Böhmer A, Jordan J, Tsikas D. High-performance liquid chromatography ultraviolet assay for human erythrocytic catalase activity by measuring glutathione as o-phthalaldehyde derivative. Anal Biochem 2011; 410: 296-303
Tsikas D, Stichtenoth DO, Jordan J. Inorganic nitrate for blood pressure lowering? Hypertension 2011; 57: e1-2
Zoerner AA, Heusser K, Gutzki FM, Mitschke A, Tank J, Stichtenoth DO, Jordan J, Tsikas D. Unique pentafluorobenzylation and collision-induced dissociation for specific and accurate GC-MS/MS quantification of the catecholamine metabolite 3,4-dihydroxyphenylglycol (DHPG) in human urine. J Chromatogr B Analyt Technol Biomed Life Sci 2011; 879: 1444-56
Tsikas D. Comments on the article "Nitrosylated human serum albumin (SNO-HSA) induces apoptosis in tumor cells (Nitric Oxide 22 (2010) 259-265)". Nitric Oxide 2011; 24: 123-4
Schroeder C, Tank J, Heusser K, Busjahn A, Diedrich A, Luft FC, Jordan J. Orthostatic tolerance is difficult to predict in recurrent syncope patients. Clin Auton Res 2011; 21: 37-45
Schwarz A, Modun D, Heusser K, Tank J, Gutzki FM, Mitschke A, Jordan J, Tsikas D. Stable-isotope dilution GC-MS approach for nitrite quantification in human whole blood, erythrocytes, and plasma using pentafluorobenzyl bromide derivatization: Nitrite distribution in human blood. J Chromatogr B Analyt Technol Biomed Life Sci 2011; 879: 1485-95
Haghikia A, Missol-Kolka E, Tsikas D, Venturini L, Brundiers S, Castoldi M, Muckenthaler MU, Eder M, Stapel B, Thum T, Haghikia A, Petrasch-Parwez E, Drexler H, Hilfiker-Kleiner D, Scherr M. Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes. Eur Heart J 2011; 32: 1287-97
Ritter B, Kilian P, Reboll MR, Resch K, DiStefano JK, Frank R, Beil W, Nourbakhsh M. Differential effects of multiplicity of infection on Helicobacter pylori-induced signaling pathways and interleukin-8 gene transcription. J Clin Immunol 2011; 31: 60-8
Tank J, Baevsky RM, Funtova II, Diedrich A, Slepchenkova IN, Jordan J. Orthostatic heart rate responses after prolonged space flights. Clin Auton Res 2011; 21: 121-4
Publikationen 2010
von Haehling S, Lainscak M, Doehner W, Ponikowski P, Rosano G, Jordan J, Rozentryt P, Rauchhaus M, Karpov R, Tkachuk V, Parfyonova Y, Zaritskey AY, Shlyakhto EV, Cleland JG, Anker SD. J Diabetes mellitus, cachexia and obesity in heart failure: rationale and design of the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF). Cachexia Sarcopenia Muscle 2010; 1: 187-194
Wolf C, Lorenzen JM, Stein S, Tsikas D, Störk S, Weidemann F, Ertl G, Anker SD, Bauersachs J, Thum T. Urinary asymmetric dimethylarginine (ADMA) is a predictor of mortality risk in patients with coronary artery disease. Int J Cardiol 2010 Dec 13. [Epub ahead of print]
Stichtenoth DO. Diabetic with lactose intolerance. Is there a drug without lactose? MMW Fortschr Med 2010; 152: 24
Dzamonja G, Tank J, Heusser K, Palada I, Valic Z, Bakovic D, Obad A, Ivancev V, Breskovic T, Diedrich A, Luft FC, Dujic Z, Jordan J. Glossopharyngeal insufflation induces cardioinhibitory syncope in apnea divers. Clin Auton Res 2010; 20: 381-4
Tank J, Heusser K, Diedrich A, Luft FC, Jordan J. A novel pharmacological approach to determining parasympathetic heart rate reserve in human subjects. Clin Pharmacol Ther 2010; 88: 630-3
Schwedhelm E, Bierend A, Maas R, Trinks R, Kom GD, Tsikas D, Böger RH. Redox-Generated Isoprostanes are Associated with Residual Platelet Activity in Aspirin-Treated Patients with Stable Coronary Heart Disease. J Thromb Haemost 2010; 8: 2662-70
Scheffers IJ, Kroon AA, Schmidli J, Jordan J, Tordoir JJ, Mohaupt MG, Luft FC, Haller H, Menne J, Engeli S, Ceral J, Eckert S, Erglis A, Narkiewicz K, Philipp T, de Leeuw PW. Novel baroreflex activation therapy in resistant hypertension: results of a European multi-center feasibility study. J Am Coll Cardiol 2010; 56: 1254-8
Picksak G, Stichtenoth DO. Hepatitis A vaccination three days before departure to Eastern Europe? Med Monatsschr Pharm 2010; 33: 261-2
Tsikas D, Zoerner AA, Gutzki FM, Rossi R. On the mercapturic acid pathway of nitric oxide: is S-nitrosoglutathione present in the bile? Hepatology 2010;52: 1858-9; author reply 1859-60
Heusser K, Dzamonja G, Breskovic T, Steinback CD, Diedrich A, Tank J, Jordan J, Dujic Z. Sympathetic and cardiovascular responses to glossopharyngeal insufflation in trained apnea divers. J Appl Physiol 2010; 109: 1728-35
Jordan J. What rare autonomic disorders can teach us about human cardiovascular pharmacology. Hypertension 2010; 56: 811-3
Tsikas D. Identifying and quantifying contaminants contributing to endogenous analytes in gas chromatography/mass spectrometry. Anal Chem 2010; 82: 7835-41
Thum T, Batkai S, Malinski PG, Becker T, Mevius I, Klempnauer J, Meyer HH, Frölich JC, Borlak J, Tsikas D. Measurement and diagnostic use of hepatic cytochrome P450 metabolism of oleic acid in liver disease. Liver Int 2010; 30: 1181-8
Krause P, Wätzig E, Acil H, König S, Unthan-Fechner K, Tsikas D, Probst I. Role of carbon monoxide and nitric oxide in adult rat hepatocytes proliferating in vitro: Effects of CAS 1609. Nitric Oxide 2010; 23: 220-6
Sato K, Urbano R, Yu C, Yamasaki F, Sato T, Jordan J, Robertson D, Diedrich A. The effect of donepezil treatment on cardiovascular mortality. Clin Pharmacol Ther 2010; 88: 335-8
Haufe S, Engeli S, Budziarek P, Utz W, Schulz-Menger J, Hermsdorf M, Wiesner S, Otto C, Haas V, de Greiff A, Luft FC, Boschmann M, Jordan J. Cardiorespiratory fitness and insulin sensitivity in overweight or obese subjects may be linked through intrahepatic lipid content. Diabetes 2010; 59: 1640-7
Picksak G, Stichtenoth DO. SSRI-associated bleeding risk. Med Monatsschr Pharm 2010; 33: 217-8
Foley JE, Jordan J. Weight neutrality with the DPP-4 inhibitor vildagliptin: mechanistic basis and clinical experience. Vascular Health and Risk Management 2010; 6: 541-8
Tsikas D, Chobanyan-Jürgens K. Quantification of Carbonate by Gas Chromatography-Mass Spectrometry. Anal Chem 2010; 82: 7897-905
Jordan J, Grassi G. Belly fat and resistant hypertension. J Hypertens 2010; 28: 1131-3
McHugh J, Keller NR, Appalsamy M, Thomas SA, Raj SR, Diedrich A, Biaggioni I, Jordan J, Robertson D. Portal osmopressor mechanism linked to transient receptor potential vanilloid 4 and blood pressure control. Hypertension 2010; 55: 1438-43
Tsikas D. Analytical methods for 3-nitrotyrosine quantification in biological samples: the unique role of tandem mass spectrometry. Amino Acids 2010 May 22. [Epub ahead of print]
Thielecke F, Rahn G, Böhnke J, Adams F, Birkenfeld AL, Jordan J, Boschmann M. Epigallocatechin-3-gallate and postprandial fat oxidation in overweight/obese male volunteers: a pilot study. Eur J Clin Nutr 2010; 64: 704-13
Dreißigacker U, Wendt M, Wittke T, Tsikas D, Maassen N. Positive correlation between plasma nitrite and performance during high-intensive exercise but not oxidative stress in healthy men. Nitric Oxide 2010; 23: 128-35
Heusser K, Tank J, Engeli S, Diedrich A, Menne J, Eckert S, Peters T, Sweep FC, Haller H, Pichlmaier AM, Luft FC, Jordan J. Carotid baroreceptor stimulation, sympathetic activity, baroreflex function, and blood pressure in hypertensive patients. Hypertension 2010; 55: 619-26
Chaudhry I, Jordan J, Cousin FR, Cavallaro R, Mostaza JM. Management of physical health in schizophrenia: international insights. European Psychiatry 2010; 25 (Suppl 2): S37-S40
Jumpertz R, Wiesner T, Blüher M, Engeli S, Bátkai S, Wirtz H, Bosse-Henck A, Stumvoll M. Circulating Endocannabinoids and N-acyl-ethanolamides in Patients with Sleep Apnea - Specific Role of Oleoylethanolamide. Exp Clin Endocrinol Diabetes 2010; 118: 591-5
May M, Jordan J. Betablockade bei Adipositas-assoziierter Hypertonie: Ein zweischneidiges Schwert. Adipositas 2010; 4: 91-4
Schleinitz D, Carmienke S, Böttcher Y, Tönjes A, Berndt J, Klöting N, Enigk B, Müller I, Dietrich K, Breitfeld J, Scholz GH, Engeli S, Stumvoll M, Blüher M, Kovacs P. Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity. Pharmacogenomics 2010; 11: 693-702
Wiesner S, Birkenfeld AL, Engeli S, Haufe S, Brechtel L, Wein J, Hermsdorf M, Karnahl B, Berlan M, Lafontan M, Sweep FC, Luft FC, Jordan J. Neurohumoral and metabolic response to exercise in water. Horm Metab Res 2010; 42: 334-9
Boschmann M, Engeli S, Moro C, Luedtke A, Adams F, Gorzelniak K, Rahn G, Mähler A, Dobberstein K, Krüger A, Schmidt S, Spuler S, Luft FC, Smith SR, Schmidt HH, Jordan J. LMNA mutations, skeletal muscle lipid metabolism, and insulin resistance. J Clin Endocrinol Metab 2010; 95: 1634-43
Tank J, Heusser K, Schroeder C, Luft FC, Jordan J. Autonomic failure in a HIV-infected patient. Clin Auton Res 2010; 20: 263-5
Tsikas D, Böhmer A, Mitschke A. Gas chromatography-mass spectrometry analysis of nitrite in biological fluids without derivatization. Anal Chem 2010; 82: 5384-90
Breskovic T, Ivancev V, Banic I, Jordan J, Dujic Z. Peripheral chemoreflex sensitivity and sympathetic nerve activity are normal in apnea divers during training season. Autonomic Neuroscience 2010; 154: 42-7
De Rop C, Picksak G, Stichtenoth DO. Gingival hyperplasia. Med Monatsschr Pharm 2010; 33: 23-4
Tsikas D, Wolf A, Mitschke A, Gutzki FM, Will W, Bader M. GC-MS determination of creatinine in human biological fluids as pentafluorobenzyl derivative in clinical studies and biomonitoring: Inter-laboratory comparison in urine with Jaffé, HPLC and enzymatic assays. J Chromatogr B Analyt Technol Biomed Life Sci. 2010; 878: 2582-92
Tsikas D. Measurement of nitrotyrosine in plasma by immunoassays is fraught with danger: commercial availability is no guarantee of analytical reliability. Clin Chem Lab Med 2010; 48: 141-3
Nachtigall J, Schulz D, Beil W, Süssmuth RD, Fiedler HP. Aranciamycin anhydride, a new anthracycline-type antibiotic isolated from Streptomyces sp. Tü 6384(*). J Antibiot (Tokyo) 2010; 63: 397-9
Tsikas D, Schwarz A, Stichtenoth DO. Simultaneous measurement of [15N]nitrate and [15N]nitrite enrichment and concentration in urine by gas chromatography mass spectrometry as pentafluorobenzyl derivatives. Anal Chem 2010; 82: 2585-7
Breskovic T, Valic Z, Lipp A, Heusser K, Ivancev V, Tank J, Dzamonja G, Jordan J, Shoemaker JK, Eterovic D, Dujic Z. Peripheral chemoreflex regulation of sympathetic vasomotor tone in apnea divers. Clin Auton Res 2010; 20: 57-63
Tsikas D. Quantitative analysis of biomarkers, drugs and toxins in biological samples by immunoaffinity chromatography coupled to mass spectrometry or tandem mass spectrometry: A focused review of recent applications. J Chromatogr B Analyt Technol Biomed Life Sci 2010; 878: 133-48
Straznicky N, Grassi G, Esler M, Lambert G, Dixon J, Lambert E, Jordan J, Schlaich M; for the European Society of Hypertension Working Group on Obesity, the Australian, New Zealand Obesity Society. European Society of Hypertension Working Group on Obesity antihypertensive effects of weight loss: myth or reality? J Hypertens 2010; 28: 637-43
Haufe S, Engeli S, Budziarek P, Utz W, Schulz-Menger J, Hermsdorf M, Wiesner S, Otto C, Fuhrmann JC, Luft FC, Boschmann M, Jordan J. Determinants of exercise-induced fat oxidation in obese women and men. Horm Metab Res 2010; 42: 215-21
Wiesner S, Haufe S, Engeli S, Mutschler H, Haas U, Luft FC, Jordan J. Influences of normobaric hypoxia training on physical fitness and metabolic risk markers in overweight to obese subjects. Obesity (Silver Spring) 2010; 18: 116-20
Dreiβigacker U, Suchy MT, Maassen N, Tsikas D. Human plasma concentrations of malondialdehyde (MDA) and the F(2)-isoprostane 15(S)-8-iso-PGF(2alpha) may be markedly compromised by hemolysis: Evidence by GC-MS/MS and potential analytical and biological ramifications. Clin Biochem 2010; 43: 159-67
Tsikas D, Mitschke A, Gutzki FM, Engeli S, Jordan J. Evidence by gas chromatography-mass spectrometry of ex vivo nitrite and nitrate formation from air nitrogen oxides in human plasma, serum, and urine samples. Anal Biochem 2010; 397: 126-8
Tsikas D, Engeli S, Beckmann B, Jordan J. Asymmetric dimethylarginine (ADMA) is present in plasma proteins of healthy subjects at the low nmol-per-g-level. Nitric Oxide 2010; 22: 316-7
Publikationen 2009
Giustarini D, Dalle-Donne I, Tsikas D, Rossi R. Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers. Crit Rev Clin Lab Sci 2009; 46: 241-81
Tsikas D. Reliable quantification of endogenous free 3-nitrotyrosine in human plasma by GC–ECD or GC–MS in health and disease? Chromatographia 2009; 70: 1767-8
Hunt RH, Lanas A, Stichtenoth DO, Scarpignato C. Myths and facts in the use of anti-inflammatory drugs. Ann Med 2009; 41: 423-37
Tsikas D, Beckmann B. Albumin from human serum does not contain asymmetric dimethylarginine (ADMA). Clin Biochem 2009; 42: 1739-40
Dujic Z, Uglesic L, Breskovic T, Valic Z, Heusser K, Marinovic J, Ljubkovic M, Palada I. Involuntary breathing movements improve cerebral oxygenation during apnea struggle phase in elite divers. J Appl Physiol 2009; 107: 1840-6
Birkenfeld AL, Jordan J, Hofmann U, Busjahn A, Franke G, Krüger N, Igel S, Mürdter T, Drescher S, Shi S, Engeli S, Schwab M, Eichelbaum M, Luft FC, Fromm MF. Genetic influences on the pharmacokinetics of orally and intravenously administered digoxin as exhibited by monozygotic twins. Clin Pharmacol Ther 2009; 86: 605-8
Pham VV, Stichtenoth DO, Tsikas D. Nitrite correlates with 3-nitrotyrosine but not with the F(2)-isoprostane 15(S)-8-iso-PGF(2alpha) in urine of rheumatic patients. Nitric Oxide 2009 21: 210-5
Schroeder C, Batkai S, Engeli S, Tank J, Diedrich A, Luft FC, Jordan J. Circulating endocannabinoid concentrations during orthostatic stress. Clin Auton Res 2009; 19: 343-6
Tsikas D, Zoerner AA, Mitschke A, Gutzki FM. Nitro-fatty acids occur in human plasma in the picomolar range: a targeted nitro-lipidomics GC-MS/MS study. Lipids 2009; 44: 855-65
Michaelsen JT, Dehnert S, Giustarini D, Beckmann B, Tsikas D. HPLC analysis of human erythrocytic glutathione forms using OPA and N-acetyl-cysteine ethyl ester: evidence for nitrite-induced GSH oxidation to GSSG. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 3405-17
Tsikas D, Dehnert S, Urban K, Surdacki A, Meyer HH. GC-MS analysis of S-nitrosothiols after conversion to S-nitroso-N-acetyl cysteine ethyl ester and in-injector nitrosation of ethyl acetate. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 3442-55
Martens-Lobenhoffer J, Schwedhelm E, Tsikas D. Quantification of arginine and its mono- and dimethylated analogs NMMA, ADMA and SDMA in biological fluids by LC-MS/MS: Is LC superfluous? J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 3261-6
Magné J, Huneau JF, Tsikas D, Delemasure S, Rochette L, Tomé D, Mariotti F. Rapeseed Protein in a High-Fat Mixed Meal Alleviates Postprandial Systemic and Vascular Oxidative Stress and Prevents Vascular Endothelial Dysfunction in Healthy Rats. J Nutr 2009; 139: 1660-6
Tsikas D. Comments on "Determination of S-nitrosoglutathione and other nitrosothiols by p-hydroxymercurybenzoate derivatization and reverse phase chromatography coupled with chemical vapor generation atomic fluorescence detection" by Bramanti et al. Talanta 2009; 79: 552-3
Andresen H, Bingel U, Streichert T, Schmoldt A, Zoerner AA, Tsikas D, Just I. Severe glycerol intoxication after Menière's disease diagnostic--case report and overview of kinetic data. Clin Toxicol 2009; 47: 312-6
de Vries DK, Lindeman JH, Tsikas D, de Heer E, Roos A, de Fijter JW, Baranski AG, van Pelt J, Schaapherder AF. Early Renal Ischemia-Reperfusion Injury in Humans Is Dominated by IL-6 Release from the Allograft. Am J Transplant 2009; 9: 1574-84
Tsikas D, Rossi R. Letter by Tsikas and Rossi regarding article, "Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction". Circulation 2009; 119: e531
Zoerner AA, Gutzki FM, Suchy MT, Beckmann B, Engeli S, Jordan J, Tsikas D. Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 2909-23
Rossi R, Tsikas D. S-Nitrosothiols in blood: does photosensitivity explain a 4-order-of-magnitude concentration range? Clin Chem 2009; 55: 1036-8
Bader M, Rosenberger W, Gutzki FM, Tsikas D. Quantification of N-(3-chloro-2-hydroxypropyl)valine in human haemoglobin as a biomarker of epichlorohydrin exposure by gas chromatography-tandem mass spectrometry with stable-isotope dilution. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 1402-15
Busjahn CA, Schulz-Menger J, Abdel-Aty H, Rudolph A, Jordan J, Luft FC, Busjahn A. Heritability of left ventricular and papillary muscle heart size: a twin study with cardiac magnetic resonance imaging. Eur Heart J 2009; Apr 30. [Epub ahead of print]
Heusser K, Dzamonja G, Tank J, Palada I, Valic Z, Bakovic D, Obad A, Ivancev V, Breskovic T, Diedrich A, Joyner MJ, Luft FC, Jordan J, Dujic Z. Cardiovascular regulation during apnea in elite divers. Hypertension 2009; 53: 719-24
Kielstein JT, Hesse G, Bahr MJ, Tsikas D, Terkamp C, Martens-Lobenhoffer J, Manns MP, Haller H, Panning B, Bode-Böger SM, Gebel M. Procedure-related pulmonary hypertension in patients with hepatocellular carcinoma undergoing percutaneous ethanol injection--role of ethanol, hemolysis, asymmetric dimethylarginine, and the nitric oxide system. Crit Care Med 2009; 37: 1483-5
Becker CDK, Stichtenoth DO, Wichmann MG, Schaefer C, Szinicz L. Blood Donors on Medication – an Approach to Minimize Drug Burden for Recipients of Blood Products and to Limit Deferral of Donors. Transfus Med Hemother 2009; 36: 107-113
Janke J, Engeli S, Gorzelniak K, Luft FC, Jordan J. Compounds used for „injection lipolysis“ destroy adipocytes and other cells found in adipose tissue. Obesity Facts 2009; 2: 36-39
Picksak G, Stichtenoth DO. Lactose-containing tablets for patients with lactose intolerance? Med Monatsschr Pharm 2009; 32: 27-8
Krausse-Opatz B, Wittkop U, Gutzki FM, Schmidt C, Jürgens-Saathoff B, Meier S, Beckmann B, Takikawa O, Morgan MA, Tsikas D, Stichtenoth DO, Wagner AD, Zeidler H, Köhler L. Free iron ions decrease indoleamine 2,3-dioxygenase expression and reduce IFNgamma-induced inhibition of Chlamydia trachomatis infection. Microb Pathog 2009; 46: 289-97
Tsikas D. A proposal for comparing methods of quantitative analysis of endogenous compounds in biological systems by using the relative lower limit of quantification (rLLOQ). J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 2244-51
Warnecke A, Luessen P, Sandmann J, Ikic M, Rossa S, Gutzki FM, Stichtenoth DO, Tsikas D. Application of a stable-isotope dilution technique to study the pharmacokinetics of human (15)N-labelled S-nitrosoalbumin in the rat: Possible mechanistic and biological implications. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 1375-87
Goncalves AC, Tank J, Diedrich A, Hilzendeger A, Plehm R, Bader M, Luft FC, Jordan J, Gross V. Diabetic hypertensive leptin receptor-deficient db/db mice develop cardioregulatory autonomic dysfunction. Hypertension 2009;53: 387-92
Tsikas D. De novo synthesis of trideuteromethyl esters of amino acids for use in GC-MS and GC-tandem MS exemplified for ADMA in human plasma and urine: Standardization, validation, comparison and proof of evidence for their aptitude as internal standards. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 2308-20
Schlaich MP, Grassi G, Lambert GW, Straznicky N, Esler MD, Dixon J, Lambert EA, Redon J, Narkiewicz K, Jordan J. European Society of Hypertension Working Group on Obesity Obesity-induced hypertension and target organ damage: current knowledge and future directions. J Hypertens 2009; 27: 207-211
Tsikas D, Zoerner A, Mitschke A, Homsi Y, Gutzki FM, Jordan J. Specific GC-MS/MS stable-isotope dilution methodology for free 9- and 10-nitro-oleic acid in human plasma challenges previous LC-MS/MS reports. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877: 2895-908
Gratze P, Boschmann M, Dechend R, Qadri F, Malchow J, Graeske S, Engeli S, Janke J, Springer J, Contrepas A, Plehm R, Klaus S, Nguyen G, Luft FC, Muller DN. Energy Metabolism in Human Renin-Gene Transgenic Rats. Does Renin Contribute to Obesity? Hypertension 2009; 53: 516-523
Schupp M, Lefterova MI, Janke J, Leitner K, Cristancho AG, Mullican SE, Qatanani M, Szwergold N, Steger DJ, Curtin JC, Kim RJ, Suh M, Albert MR, Engeli S, Gudas LJ, Lazar MA. Retinol saturase promotes adipogenesis and is downregulated in obesity. Proc Natl Acad Sci USA 2009; 106: 1105-10
Bernateck M, Karst M, Eberhard S, Vivell W, Fischer MJ, Stichtenoth DO. Placebo therapy: Analysis of extent and expectations in a tertiary referral center. Schmerz 2009; 23: 47-53
Becker T, Mevius I, de Vries DK, et al. The l-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: Biological and analytical ramifications. Nitric Oxide 2009; 20: 61-7
Schroeder C, Heusser K, Tank J, Diedrich A, Luft FC, Jordan J. The Valsalva maneuver: screening for drug-induced baroreflex dysfunction. Clin Auton Res 2009; 19: 32-8.
Kressel G, Trunz B, Bub A, Hülsmann O, Wolters M, Lichtinghagen R, Stichtenoth DO, Hahn A. Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk. Atherosclerosis 2009; 202: 263-71
Tsikas D, Hohlfeld JM. On the importance of the use of proper approaches for comparison of analytical methods for serum nitrate and for evaluation of reference concentrations. Clin Biochem 2009; 42: 1200-1
Frank H, Heusser K, Geiger H, Fahlbusch R, Naraghi R, Schobel HP. Temporary Reduction of Blood Pressure and Sympathetic Nerve Activity in Hypertensive Patients After Microvascular Decompression. Stroke 2009; 40: 47-51.
Boschmann M, Engeli S, Dobberstein K, Budziarek P, Strauss A, Boehnke J, Sweep FC, Luft FC, He Y, Foley JE, Jordan J. Dipeptidyl-Peptidase-IV Inhibition Augments Postprandial Lipid Mobilization and Oxidation in Type 2 Diabetic Patients. J Clin Endocrinol Metab 2009; 94: 846-852