
Waggoner SN, Cornberg M, Selin LK, Welsh RM.
Natural killer cells act as rheostats modulating antiviral T cells.
Nature. 2011 Nov 20. doi: 10.1038/nature10624. PMID: 22101430
Petersen J, Ratziu V, Buti M, Janssen HL, Brown A, Lampertico P, Schollmeyer J, Zoulim F, Wedemeyer H, Sterneck M, Berg T, Sarrazin C, Lutgehetmann M, Buggisch P.
Entecavir Plus Tenofovir Combination as Rescue Therapy in Pretreated Chronic Hepatitis B Patients. An International Multicenter Cohort Study.
J Hepatol. 2011 Oct 26. PMID: 22037226
Suneetha PV, Pischke S, Schlaphoff V, Grabowski J, Fytili P, Gronert Alvarez A, Bremer B, Markova A, Jaroszewicz J, Bara C, Manns MP, Cornberg M, Wedemeyer H.
HEV-specific T-cell responses are associated with control of HEV infection.
Hepatology. 2011 Oct 17. doi: 10.1002/hep.24738. PMID: 22006345
Voigtländer T, Cornberg M, Kubitz R, Schlue J, Manns MP, Lankisch T.
Unexplained jaundice after squirrel bite. It's not what you look at that matters, it's what you see (H. D. Thoreanu).
J Gastrointestin Liver Dis. 2011 Sep;20(3):331-2. PMID: 21961108
Hatzakis A, Wait S, Bruix J, Buti M, Carballo M, Cavaleri M, Colombo M, Delarocque-Astagneau E, Dusheiko G, Esmat G, Esteban R, Goldberg D, Gore C, Lok AS, Manns M, Marcellin P, Papatheodoridis G, Peterle A, Prati D, Piorkowsky N, Rizzetto M, Roudot-Thoraval F, Soriano V, Thomas HC, Thursz M, Valla D, van Damme P, Veldhuijzen IK, Wedemeyer H, Wiessing L, Zanetti AR, Janssen HL.
The state of hepatitis B and C in Europe: report from the hepatitis B and C summit conference*.
J Viral Hepat. 2011 Sep;18 Suppl 1:1-16. doi: 10.1111/j.1365-2893.2011.01499.x. PMID: 21824223
Jaroszewicz J, Ho H, Markova A, Deterding K, Wursthorn K, Schulz S, Bock CT, Tillmann HL, Manns MP, Wedemeyer H, Cornberg M.
Hepatitis B surface antigen (HBsAg) decrease and serum interferon-inducible protein-10 levels as predictive markers for HBsAg loss during treatment with nucleoside/nucleotide analogues.
Antivir Ther. 2011;16(6):915-24. PMID: 21900724
Pischke S, Heim A, Bremer B, Raupach R, Horn-Wichmann R, Ganzenmueller T, Klose B, Goudeva L, Wagner F, Oehme A, Manns MP, Wedemeyer H.
Hepatitis E: an emerging infectious disease in Germany?
Z Gastroenterol. 2011 Sep;49(9):1255-7. Epub 2011 Sep 1. PMID: 21887661
Zacher BJ, Moriconi F, Bowden S, Hammond R, Louisirirotchanakul S, Phisalprapa P, Tanwandee T, Wursthorn K, Brunetto MR, Wedemeyer H, Bonino F.
Multicenter evaluation of the elecsys hepatitis B surface antigen quantitative assay.
Clin Vaccine Immunol. 2011 Nov;18(11):1943-50. Epub 2011 Aug 31. PMID: 21880853
Ciesek S, von Hahn T, Colpitts CC, Schang LM, Friesland M, Steinmann J, Manns MP, Ott M, Wedemeyer H, Meuleman P, Pietschmann T, Steinmann E.
The green tea polyphenol epigallocatechin-3-gallate (EGCG) inhibits hepatitis C virus (HCV) entry.
Hepatology. 2011 Aug 11. doi: 10.1002/hep.24610. PMID: 21837753
Si-Ahmed SN, Pradat P, Zoutendijk R, Buti M, Mallet V, Cruiziat C, Deterding K, Dumortier J, Bailly F, Esteban R, Wedemeyer H, Janssen HL, Zoulim F.
Efficacy and tolerance of a combination of tenofovir disoproxil fumarate plus emtricitabine in patients with chronic hepatitis B: a European multicenter study.
Antiviral Res. 2011 Oct;92(1):90-5. Epub 2011 Jul 13. PMID: 21767570
Mederacke I, Filmann N, Yurdaydin C, Bremer B, Puls F, Zacher BJ, Heidrich B, Tillmann HL, Rosenau J, Bock CT, Savas B, Helfritz F, Lehner F, Strassburg CP, Klempnauer J, Wursthorn K, Lehmann U, Manns MP, Herrmann E, Wedemeyer H.
Rapid early HDV RNA decline in the peripheral blood but prolonged intrahepatic hepatitis delta antigen persistence after liver transplantation.
J Hepatol. 2011 Jul 14. PMID: 21762665
Grabowski J, Yurdaydìn C, Zachou K, Buggisch P, Hofmann WP, Jaroszewicz J, Schlaphoff V, Manns MP, Cornberg M, Wedemeyer H; the HIDIT-1 study group.
Hepatitis D virus-specific cytokine responses in patients with chronic hepatitis delta before and during interferon alfa-treatment.
Liver Int. 2011 Jul 15. doi: 10.1111/j.1478-3231.2011.02593.x. PMID: 21762356
Cornberg M, Protzer U, Petersen J, Wedemeyer H, Berg T, Jilg W, Erhardt A, Wirth S, Sarrazin C, Dollinger MM, Schirmacher P, Dathe K, Kopp IB, Zeuzem S, Gerlich WH, Manns MP; AWMF.
[Prophylaxis, diagnosis and therapy of hepatitis B virus infection - the German guideline].
Z Gastroenterol. 2011 Jul;49(7):871-930. Epub 2011 Jul 11. PMID: 21748700
Chan HL, Thompson A, Martinot-Peignoux M, Piratvisuth T, Cornberg M, Brunetto MR, Tillmann HL, Kao JH, Jia JD, Wedemeyer H, Locarnini S, Janssen HL, Marcellin P; for the Good Practice in using sAg in Chronic Hepatitis B Study Group (GPs-CHB Study Group).
Hepatitis B surface antigen Quantification: Why and How to use it in 2011 - A Core Group Report.
J Hepatol. 2011 Nov;55(5):1121-31. Epub 2011 Jun 28. PMID: 21718667
Nattermann J, Timm J, Nischalke HD, Olbrich A, Michalk M, Tilmann HL, Berg T, Wedemeyer H, Tenckhoff H, Wiese M, Kullig U, Göbel U, Capka E, Schiefke I, Güthoff W, Grüngreiff K, König I, Roggendorf M, Sauerbruch T, Spengler U; for the East German HCV study group.
The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation.
J Hepatol. 2011 Apr 13. PMID: 21703201
Jacobson IM, McHutchison JG, Dusheiko G, Di Bisceglie AM, Reddy KR, Bzowej NH, Marcellin P, Muir AJ, Ferenci P, Flisiak R, George J, Rizzetto M, Shouval D, Sola R, Terg RA, Yoshida EM, Adda N, Bengtsson L, Sankoh AJ, Kieffer TL, George S, Kauffman RS, Zeuzem S; ADVANCE Study Team.
Telaprevir for previously untreated chronic hepatitis C virus infection.
N Engl J Med. 2011 Jun 23;364(25):2405-16. PMID: 21696307
Deterding K, Naesens L, Buti M, Janssen H, Kirschner J, Guerrero A, Reijnders J, Neyts J, Zoulim F, Wedemeyer H.
Adefovir serum levels do not differ between responders and nonresponders.
J Viral Hepat. 2011 Jul;18(7):e175-8. doi: 10.1111/j.1365-2893.2010.01404.x. Epub 2011 Jan 7. PMID: 21692930
von Hahn T, Ciesek S, Wegener G, Plentz RR, Weismüller TJ, Wedemeyer H, Manns MP, Greten TF, Malek NP.
Epidemiological trends in incidence and mortality of hepatobiliary cancers in Germany.
Scand J Gastroenterol. 2011 Sep;46(9):1092-8. Epub 2011 Jun 22. PMID: 21692710
Cornberg M, Razavi HA, Alberti A, Bernasconi E, Buti M, Cooper C, Dalgard O, Dillion JF, Flisiak R, Forns X, Frankova S, Goldis A, Goulis I, Halota W, Hunyady B, Lagging M, Largen A, Makara M, Manolakopoulos S, Marcellin P, Marinho RT, Pol S, Poynard T, Puoti M, Sagalova O, Sibbel S, Simon K, Wallace C, Young K, Yurdaydin C, Zuckerman E, Negro F, Zeuzem S.
A systematic review of hepatitis C virus epidemiology in Europe, Canada and Israel.
Liver Int. 2011 Jul;31 Suppl 2:30-60. PMID: 21651702
Ciesek S, Westhaus S, Wicht M, Wappler I, Henschen S, Sarrazin C, Hamdi N, Abdelaziz AI, Strassburg CP, Wedemeyer H, Manns MP, Pietschmann T, von Hahn T.
Impact of occludin intra- and inter-species variation on its co-receptor function for authentic hepatitis C virus particles.
J Virol. 2011 Aug;85(15):7613-21. Epub 2011 Jun 1. PMID: 21632765
Schlaphoff V, Lunemann S, Suneetha PV, Jaroszewicz J, Grabowski J, Dietz J, Helfritz F, Bektas H, Sarrazin C, Manns MP, Cornberg M, Wedemeyer H.
Dual Function of the NK Cell Receptor 2B4 (CD244) in the Regulation of HCV-Specific CD8+ T Cells.
PLoS Pathog. 2011 May;7(5):e1002045. PMID: 21625589
Zoutendijk R, Reijnders JG, Brown A, Zoulim F, Mutimer D, Deterding K, Petersen J, Hofmann WP, Buti M, Santantonio T, van Bömmel F, Pradat P, Oo Y, Luetgehetmann M, Berg T, Hansen BE, Wedemeyer H, Janssen HL; for the VIRGIL Surveillance Study Group.
Entecavir treatment for chronic hepatitis B: Adaptation is not needed for the majority of naïve patients with a partial virological response.
Hepatology. 2011 Aug;54(2):443-51. doi: 10.1002/hep.24406. PMID: 21563196
Rockstroh JK, Peters L, Wedemeyer H.
Is there a need for liver disease monitoring in HIV patients in Africa?
Antivir Ther. 2011;16(3):287-9. PMID: 21555810
Hartmann D, Srivastava U, Thaler M, Kleinhans KN, N'kontchou G, Scheffold A, Bauer K, Kratzer RF, Kloos N, Katz SF, Song Z, Begus-Nahrmann Y, Kleger A, von Figura G, Strnad P, Lechel A, Günes C, Potthoff A, Deterding K, Wedemeyer H, Ju Z, Song G, Xiao F, Gillen S, Schrezenmeier H, Mertens T, Ziol M, Friess H, Jarek M, Manns MP, Beaugrand M, Rudolph KL.
Telomerase gene mutations are associated with cirrhosis formation.
Hepatology. 2011 May;53(5):1608-17. doi: 10.1002/hep.24217. PMID: 21520174
Li Y, Mederacke I, Scheumann GF, Baraki H, Wedemeyer H, Kutschka I.
Simultaneous Mitral Valve Replacement and Liver Transplantation.
Thorac Cardiovasc Surg. 2011 Apr 21. PMID: 21512977
Hughes SA, Wedemeyer H, Harrison PM.
Hepatitis delta virus.
Lancet. 2011 Jul 2;378(9785):73-85. Epub 2011 Apr 20. PMID: 21511329
Trépo E, Pradat P, Potthoff A, Momozawa Y, Quertinmont E, Gustot T, Lemmers A, Berthillon P, Amininejad L, Chevalier M, Devière J, Manns M, Trépo C, Sninsky J, Wedemeyer H, Franchimont D, Moreno C.
Impact of PNPLA3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C.
Hepatology. 2011 Jul;54(1):60-9. doi: 10.1002/hep.24350. PMID: 21488075
Bacon BR, Gordon SC, Lawitz E, Marcellin P, Vierling JM, Zeuzem S, Poordad F, Goodman ZD, Sings HL, Boparai N, Burroughs M, Brass CA, Albrecht JK, Esteban R; HCV RESPOND-2 Investigators.
Boceprevir for previously treated chronic HCV genotype 1 infection.
N Engl J Med. 2011 Mar 31;364(13):1207-17. PMID: 21449784
Rifai K, Cornberg J, Mederacke I, Bahr MJ, Wedemeyer H, Malinski P, Bantel H, Boozari B, Potthoff A, Manns MP, Gebel M.
Clinical feasibility of liver elastography by acoustic radiation force impulse imaging (ARFI).
Dig Liver Dis. 2011 Jun;43(6):491-7. Epub 2011 Mar 24. PMID: 21439919
Wursthorn K, Wedemeyer H, Manns MP.
Republished paper: Managing HBV in patients with impaired immunity.
Postgrad Med J. 2011 Mar;87(1025):223-38. PMID: 21357572
Cornberg M, Manns MP.
[Prevention of virus hepatitis A to E].
Internist (Berl). 2011 Mar;52(3):250-64. German.
PMID: 21340533
Pischke S, Karsten W, Hadem J, Schmidt S, Heiringhoff Heinz K, Helfritz F,
Strassburg CP, Lobers J, Zender L, Tutarel O, Wedemeyer J, Manns MP, Wedemeyer H, Rifai K, Gebel M.
Liver transplantation: A new risk factor for intestinal intussusceptions.
Ann Hepatol. 2011 Jan 3;10(1):38-42. PMID: 21301008.
Mederacke I, Meier M, Lüth JB, Schmidt-Gürtler H, Raupach R, Horn-Wichmann R,
Wursthorn K, Potthoff A, Colucci G, Manns MP, Wedemeyer H, Tillmann HL.
Different kinetics of HBV and HCV during haemodialysis and absence of seronegative viral hepatitis in patients with end-stage renal disease.
Nephrol Dial Transplant. 2011 Aug;26(8):2648-56. Epub 2011 Jan 27. PMID: 21273235.
Wursthorn K, Jaroszewicz J, Zacher BJ, Darnedde M, Raupach R, Mederacke I,
Cornberg M, Manns MP, Wedemeyer H.
Correlation between the Elecsys HBsAg II assay and the Architect assay for the quantification of hepatitis B surface antigen (HBsAg) in the serum.
J Clin Virol. 2011 Apr;50(4):292-6. Epub 2011 Jan 26. PMID: 21273117.
Wedemeyer H, Yurdaydìn C, Dalekos GN, Erhardt A, Çakaloğlu Y, Değertekin H, Gürel S, Zeuzem S, Zachou K, Bozkaya H, Koch A, Bock T, Dienes HP, Manns MP; HIDIT Study Group.
Peginterferon plus adefovir versus either drug alone for hepatitis delta.
N Engl J Med. 2011 Jan 27;364(4):322-31. PMID: 21268724.
Wedemeyer H.
Hepatitis D revival.
Liver Int. 2011 Jan;31 Suppl 1:140-4. PMID: 21205152.
Manns M, Zeuzem S, Sood A, Lurie Y, Cornberg M, Klinker H, Buggisch P, Rössle M, Hinrichsen H, Merican I, Ilan Y, Mauss S, Abu-Mouch S, Horban A, Müller TH, Welsch C, Chen R, Faruqi R, Pedicone LD, Wedemeyer H.
Reduced Dose and Duration of Peginterferon alfa-2b and Weight-Based Ribavirin in Patients With Genotype 2 and 3 Chronic Hepatitis C.
J Hepatol. 2011 Sep;55(3):554-63. Epub 2011 Jan 13. PMID: 21237227.
Torresi J, Johnson D, Wedemeyer H.
Progress in the development of preventive and therapeutic vaccines for hepatitis C virus.
J Hepatol. 2011 Jun;54(6):1273-85. Epub 2011 Jan 12 PMID: 21236312.
Wedemeyer H, Pischke S.
Hepatitis: Hepatitis E vaccination--is HEV 239 the breakthrough?
Nat Rev Gastroenterol Hepatol. 2011 Jan;8(1):8-10. PMID: 21212772.
Cornberg M, Manns MP.
[Current Guidelines for treatment of hepatitis B. Correct diagnosis is the prerequisite.].
Pharm Unserer Zeit. 2011 Jan;40(1):45-51.
PMID: 21194082
Wursthorn K, Zacher BJ, Jaroszewicz J, Darnedde M, Manns M, Wedemeyer H.
Development of a protocol for the quantitative determination of HBeAg using the
Elecsys HBeAg immunoassay.
J Viral Hepat. 2010 Dec 30. PMID: 21199189.
Trépo E, Potthoff A, Pradat P, Bakshi R, Young B, Lagier R, Moreno C, Verset L, Cross R, Degré D, Lemmers A, Gustot T, Berthillon P, Rosenberg W, Trépo C, Sninsky J, Adler M, Wedemeyer H.
Role of a cirrhosis risk score for the early prediction of fibrosis progression in hepatitis C patients with minimal liver disease.
J Hepatol. 2010 Nov 23. PMID: 21145859
Cornberg M, Jaroszewicz J, Manns MP, Wedemeyer H.
Treatment of chronic hepatitis B.
Minerva Gastroenterol Dietol. 2010 Dec;56(4):451-65.PMID: 21139543
Mederacke I, Witte T, Wedemeyer H, Meyer-Olson D.
Successful clearance of hepatitis C virus with pegylated interferon {alpha}-2a and ribavirin in an etanercept-treated patient with psoriatic arthritis, hepatitis B virus coinfection and latent tuberculosis.
Ann Rheum Dis. 2010 Dec 3. PMID: 21131645
Wedemeyer H.
From volcano clouds to iLivers: EASL growing in times of change.
J Hepatol. 2011 Jan;54(1):4-5. PMID: 21115150
Boozari B, Potthoff A, Mederacke I, Hahn A, Reising A, Rifai K, Wedemeyer H, Bahr M, Kubicka S, Manns M, Gebel M.
Evaluation of sound speed for detection of liver fibrosis: prospective comparison with transient dynamic elastography and histology.
J Ultrasound Med. 2010 Nov;29(11):1581-8.PMID: 20966469
Becker PD, Legrand N, van Geelen CM, Noerder M, Huntington ND, Lim A, Yasuda E, Diehl SA, Scheeren FA, Ott M, Weijer K, Wedemeyer H, Di Santo JP, Beaumont T, Guzman CA, Spits H.
Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice.
PLoS One. 2010 Oct 4;5(10). pii: e13137.PMID: 20957227
Wursthorn K, Jung M, Riva A, Goodman ZD, Lopez P, Bao W, Manns MP, Wedemeyer H, Naoumov NV.
Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients.
Hepatology. 2010 Nov;52(5):1611-20.PMID: 20931556
Ernst D, Pischke S, Greer M, Wedemeyer HH, Stoll M.
No increased incidence for GB-Virus C infection in a cohort of HIV-positive Lymphoma patients.
Int J Cancer. 2010 Aug 19. PMID: 20726003
Tillmann HL, Thompson AJ, Patel K, Wiese M, Tenckhoff H, Nischalke HD, Lokhnygina Y, Kullig U, Göbel U, Capka E, Wiegand J, Schiefke I, Güthoff W, Grüngreiff K, König I, Spengler U, McCarthy J, Shianna KV, Goldstein DB, McHutchison JG, Timm J, Nattermann J; German Anti-D Study Group.
A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice.
Gastroenterology. 2010 Nov;139(5):1586-92, 1592.e1. .PMID: 20637200
Bürgel B, Friesland M, Koch A, Manns MP, Wedemeyer H, Weissenborn K, Schulz-Schaeffer WJ, Pietschmann T, Steinmann E, Ciesek S.
Hepatitis C virus enters human peripheral neuroblastoma cells - evidence for extra-hepatic cells sustaining hepatitis C virus penetration.
J Viral Hepat. 2010 Jun 23. PMID: 20579278
Wursthorn K, Wedemeyer H, Manns MP.
Managing HBV in patients with impaired immunity.
Gut. 2010 Jun 4. PMID: 20525968
Pischke S, Potthoff A, Hauröder B, Schlué J, Manns MP, Cornberg M, Wedemeyer H.
[Hepatitis E virus infection: a paradigm shift?]
Dtsch Med Wochenschr. 2010 Jun;135(22):1129-33. Epub 2010 May 25. Review. German. PMID: 20503140
Pischke S, Wedemeyer H.
Chronic hepatitis E in liver transplant recipients: a significant clinical problem?
Minerva Gastroenterol Dietol. 2010 Jun;56(2):121-8.PMID: 20485250
Grabowski J, Wedemeyer H.
Hepatitis delta: immunopathogenesis and clinical challenges.
Dig Dis. 2010;28(1):133-8. Epub 2010 May 7. PMID: 20460901
Ciesek S, Friesland M, Steinmann J, Becker B, Wedemeyer H, Manns MP, Steinmann J, Pietschmann T, Steinmann E.
How Stable Is the Hepatitis C Virus (HCV)? Environmental Stability of HCV and Its Susceptibility to Chemical Biocides.
J Infect Dis. 2010 May 4. PMID: 20441517
Mederacke I, Bremer B, Heidrich B, Kirschner J, Deterding K, Bock T, Wursthorn K, Manns MP, Wedemeyer H.
Establishment of a novel quantitative HDV RNA assay using the COBAS TaqMan platform to study HDV RNA kinetics.
J Clin Microbiol. 2010 Mar 29. PMID: 20351206
Wedemeyer H.
Re-emerging interest in hepatitis delta: new insights into the dynamic interplay between HBV and HDV.
J Hepatol. 2010 May;52(5):627-9. Epub 2010 Mar 4. No abstract available. PMID: 20334947
Stegmann KA, Björkström NK, Veber H, Ciesek S, Riese P, Wiegand J, Hadem J, Suneetha PV, Jaroszewicz J, Wang C, Schlaphoff V, Fytili P, Cornberg M, Manns MP, Geffers R, Pietschmann T, Guzmán CA, Ljunggren HG, Wedemeyer H.
Interferon-alpha-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection.
Gastroenterology. 2010 May;138(5):1885-97. Epub 2010 Feb 2. PMID: 20334827
Jaroszewicz J, Serrano BC, Wursthorn K, Deterding K, Schlue J, Raupach R, Flisiak R, Bock CT, Manns MP, Wedemeyer H, Cornberg M.
Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: A European perspective.
J Hepatol. 2010 Feb 13. PMID: 20207438
Cornberg M, Clute SC, Watkin LB, Saccoccio FM, Kim SK, Naumov YN, Brehm MA, Aslan N, Welsh RM, Selin LK.
CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections.
J Immunol. 2010 Mar 15;184(6):2825-38. Epub 2010 Feb 17.PMID: 20164414
Mederacke I, Wursthorn K, Ho H, Manns MP, Wedemeyer H.
[Interferon-alfa induced reactivation of sarcoidosis in a patient with chronic hepatitis C.]
Internist (Berl). 2010 Feb 27. German. PMID: 20186385
Reijnders JG, Deterding K, Petersen J, Zoulim F, Santantonio T, Buti M, van Bömmel F, Hansen BE, Wedemeyer H, Janssen HL; for the VIRGIL Surveillance Study Group.
Antiviral effect of entecavir in chronic hepatitis B: Influence of prior exposure to nucleos(t)ide analogues.
J Hepatol. 2010 Feb 4. PMID: 20185191
Potthoff A, Manns MP, Wedemeyer H.
Treatment of HBV/HCV coinfection.
Expert Opin Pharmacother. 2010 Feb 18. PMID: 20166841
Ciesek S, Steinmann E, Iken M, Ott M, Helfritz FA, Wappler I, Manns MP, Wedemeyer H, Pietschmann T.
Glucocorticosteroids Increase Cell Entry by Hepatitis C Virus.
Gastroenterology. 2010 Feb 10. PMID: 20152835
Stange MA, Tutarel O, Pischke S, Schneider A, Strassburg CP, Becker T, Barg-Hock H, Bastürk M, Wursthorn K, Cornberg M, Ott M, Greten TF, Manns MP, Wedemeyer H.
Fulminant Hepatic Failure due to Chemotherapy-Induced Hepatitis B Reactivation: Role of Rituximab.
Z Gastroenterol. 2010 Feb;48(2):258-263. Epub 2010 Feb 2.PMID: 20127601
Sarrazin C, Berg T, Ross RS, Schirmacher P, Wedemeyer H, Neumann U, Schmidt HH, Spengler U, Wirth S, Kessler HH, Peck-Radosavljevic M, Ferenci P, Vogel W, Moradpour D, Heim M, Cornberg M, Protzer U, Manns MP, Fleig WE, Dollinger MM, Zeuzem S.
Prophylaxis, Diagnosis and Therapy of Hepatitis C Virus (HCV) Infection: The German Guidelines on the Management of HCV Infection.
Z Gastroenterol. 2010 Feb;48(2):289-351. Epub 2010 Jan 29. No abstract available. PMID: 20119896
Wedemeyer H, Hofmann WP, Lueth S, Malinski P, Thimme R, Tacke F, Wiegand J.
[ALT screening for chronic liver diseases: scrutinizing the evidence]
Z Gastroenterol. 2010 Jan;48(1):46-55. Epub 2010 Jan 13. German. PMID: 20072996
Pischke S, Ehmer U, Schedel I, Gratz WF, Wedemeyer H, Ziesing S, Bange FC, Burchard GD, Manns MP, Bahr MJ, Strassburg CP.
Of guinea pigs and men--an unusual case of jaundice.
Z Gastroenterol. 2010 Jan;48(1):33-7. Epub 2010 Jan 13.PMID: 20072994
Wedemeyer H, Manns MP.
Epidemiology, pathogenesis and management of hepatitis D: update and challenges ahead.
Nat Rev Gastroenterol Hepatol. 2010 Jan;7(1):31-40.PMID: 20051970
Pischke S, Ho H, Urbanek F, Meyer-Olsen D, Suneetha PV, Manns MP, Stoll M, Wedemeyer H.
Hepatitis E in HIV-positive patients in a low-endemic country.
J Viral Hepat. . No abstract available. PMID: 20002566
van Bömmel F, de Man RA, Wedemeyer H, Deterding K, Petersen J, Buggisch P, Erhardt A, Hüppe D, Stein K, Trojan J, Sarrazin C, Böcher WO, Spengler U, Wasmuth HE, Reinders JG, Möller B, Rhode P, Feucht HH, Wiedenmann B, Berg T.
Long-term efficacy of tenofovir monotherapy for hepatitis B virus-monoinfected patients after failure of nucleoside/nucleotide analogues.
Hepatology. 2010 Jan;51(1):73-80.PMID: 19998272
Ciesek S, Rifai K, Bahr MJ, Boozari B, Steinmann E, Helfritz FA, Wedemeyer H, Manns MP, Gebel M.
Membranous Budd-Chiari syndrome in Caucasians.
Scand J Gastroenterol. 2010;45(2):226-34. PMID: 19958053
Jirmo AC, Koya RC, Sundarassety BS, Pincha M, Yu GY, Lai M, Bakshi R, Schlaphoff V, Grabowski J, Behrens G, Wedemeyer H, Stripecke R.
Monocytes transduced with lentiviral vectors expressing hepatitis C virus non-structural proteins and differentiated into dendritic cells stimulate multi-antigenic CD8(+) T cell responses.
Vaccine. 2010 Jan 22;28(4):922-33. Epub 2009 Nov 18. PMID: 19931383
Strassburg CP, Cornberg M.
[Diagnostics and therapy of hepatitis.]
Internist (Berl). 2009 Dec;50(12):1358-68. PMID: 19921110
Beckmann MG, Bahr MJ, Hadem J, Bredt M, Wedemeyer H, Schneider AS, Kubicka S, Manns MP, Strassburg CP, Wedemeyer J.
Clinical relevance of transjugular liver biopsy in comparison with percutaneous and laparoscopic liver biopsy.
Gastroenterol Res Pract. 2009;2009:947014. Epub 2009 Nov 15.PMID: 19920868
Wedemeyer H.
EASL transitioning into the new decade.
J Hepatol. 2009 Oct 29. PMID: 19910072
Potthoff A, Berg T, Wedemeyer H.
Late hepatitis B virus relapse in patients co-infected with hepatitis B virus and hepatitis C virus after antiviral treatment with pegylated interferon-a2b and ribavirin.
Scand J Gastroenterol. 2009;44(12):1487-90. PMID: 19900055
Wiegand J, Meya S, Schlaphoff V, Manns MP, Mössner J, Wedemeyer H, Tillmann HL.
HBV-specific T-cell responses in healthy seronegative sexual partners of patients with chronic HBV infection.
J Viral Hepat. 2009 Nov 2. PMID: 19889141
Pischke S, Suneetha P, Baechlein C, Barg-Hock H, Heim A, Kamar N, Schlue J, Strassburg C, Lehner F, Raupach R, Bremer B, Magerstedt P, Cornberg M, Seehusen F, Baumgaertner W, Klempnauer J, Izopet J, Manns M, Grummer B, Wedemeyer H.
Hepatitis E virus infection as a cause of graft hepatitis in liver transplant recipients.
Liver Transpl. 2010 Jan;16(1):74-82. PMID: 19866448
Wang C, Heim A, Schlaphoff V, Suneetha PV, Stegmann KA, Jiang H, Krueger M, Fytili P, Schulz T, Cornberg M, Kandolf R, Manns MP, Bock CT, Wedemeyer H.
Intrahepatic long-term persistence of parvovirus B19 and its role in chronic viral hepatitis.
J Med Virol. 2009 Dec;81(12):2079-88 PMID: 19856479
Nie S, Cornberg M, Selin LK.
Resistance to vaccinia virus is less dependent on TNF under conditions of heterologous immunity.
J Immunol. 2009 Nov 15;183(10):6554-60. Epub 2009 Oct 21.PMID: 19846867
Deterding K, Grüngreiff K, Lankisch TO, Potthoff A, Bahr MJ, Manns MP, Wedemeyer H, Strassburg CP.
Gilbert's syndrome and antiviral therapy of hepatitis C.
Ann Hepatol. 2009 Jul-Sep;8(3):246-50. PMID: 19841506
Zachou K, Yurdaydin C, Drebber U, Dalekos GN, Erhardt A, Cakaloglu Y, Degertekin H, Gurel S, Zeuzem S, Bozkaya H, Schlaphoff V, Dienes HP, Bock TC, Manns MP, Wedemeyer H; for HIDT-1 Study Group.
Quantitative HBsAg and HDV-RNA levels in chronic delta hepatitis.
Liver Int. 2009 Oct 15. [Epub ahead of print] PMID: 19840253
Pradat P, Trepo E, Potthoff A, Bakshi R, Young B, Trepo C, Lagier R, Moreno C, Lemmers A, Gustot T, Degre D, Adler M, Wedemeyer H.
The cirrhosis risk score predicts liver fibrosis progression in patients with initially mild chronic hepatitis C.
Hepatology. 2010 Jan;51(1):356-7. PMID: 19824080
Ciesek S, Steinmann E, Wedemeyer H, Manns MP, Neyts J, Tautz N, Madan V, Bartenschlager R, von Hahn T, Pietschmann T.
Cyclosporine A inhibits hepatitis C virus nonstructural protein 2 through cyclophilin A.
Hepatology. 2009 Nov;50(5):1638-45. PMID: 19821520
Mederacke I, Wedemeyer H, Ciesek S, Steinmann E, Raupach R, Wursthorn K, Manns MP, Tillmann HL.
Performance and clinical utility of a novel fully automated quantitative HCV-core antigen assay.
J Clin Virol. 2009 Nov;46(3):210-5. Epub 2009 Sep 17. PMID: 19766055
Mederacke I, Wursthorn K, Kirschner J, Rifai K, Manns MP, Wedemeyer H, Bahr MJ.
Food intake increases liver stiffness in patients with chronic or resolved hepatitis C virus infection.
Liver Int. 2009 Nov;29(10):1500-6. Epub 2009 Sep 3. PMID: 19732330
Haridass D, Yuan Q, Becker PD, Cantz T, Iken M, Rothe M, Narain N, Bock M, Nörder M, Legrand N, Wedemeyer H, Weijer K, Spits H, Manns MP, Cai J, Deng H, Di Santo JP, Guzman CA, Ott M.
Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice.
Am J Pathol. 2009 Oct;175(4):1483-92. Epub 2009 Aug 28.PMID: 19717639
Potthoff A, Rifai K, Wedemeyer H, Deterding K, Manns M, Strassburg C.
Successful treatment of fulminant hepatitis B during pregnancy.
Z Gastroenterol. 2009 Jul;47(7):667-70. Epub 2009 Jul 15.PMID: 19606409
Heidrich B, Deterding K, Tillmann HL, Raupach R, Manns MP, Wedemeyer H. Virological and clinical characteristics of delta hepatitis in Central Europe.J Viral Hepat. 2009 Dec;16(12):883-94. Epub 2009 Jun 28. PMID: 19566789
Wedemeyer H, Schuller E, Schlaphoff V, Stauber RE, Wiegand J, Schiefke I, Firbas C, Jilma B, Thursz M, Zeuzem S, Hofmann WP, Hinrichsen H, Tauber E, Manns MP, Klade CS.
Therapeutic vaccine IC41 as late add-on to standard treatment in patients with chronic hepatitis C.
Vaccine. 2009 Aug 13;27(37):5142-51. Epub 2009 Jun 24 PMID: 19559112
Hoechst B, Voigtlaender T, Ormandy L, Gamrekelashvili J, Zhao F, Wedemeyer H, Lehner F, Manns MP, Greten TF, Korangy F.
Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor.
Hepatology. 2009 Sep;50(3):799-807 PMID: 19551844
Dintsios CM, Haverkamp A, Wiegand J, Gerlach T, Wedemeyer H, Pape G, Manns MP, Krauth C.
Economic evaluation of early monotherapy versus delayed monotherapy or combination therapy in patients with acute hepatitis C in Germany.
Eur J Gastroenterol Hepatol. 2010 Mar;22(3):278-88 PMID: 19550347
Vogel M, Deterding K, Wiegand J, Grüner NH, Baumgarten A, Jung MC, Manns MP, Wedemeyer H, Rockstroh JK; German Hepatitis Group; Hep-Net.
Initial presentation of acute hepatitis C virus (HCV) infection among HIV-negative and HIV-positive individuals-experience from 2 large German networks on the study of acute HCV infection.
Clin Infect Dis. 2009 Jul 15;49(2):317-9; PMID: 19538070
Deterding K, Wiegand J, Grüner N, Hahn A, Jäckel E, Jung MC, Buggisch P, Galle P, Berg T, Hinrichsen H, Potthoff A, Zeuzem S, Cornberg M, Manns M, Wedemeyer H.
The German Hep-Net Acute Hepatitis C Cohort: Impact of Viral and Host Factors on the Initial Presentation of Acute Hepatitis C Virus Infection.
Z Gastroenterol. 2009 Jun;47(6):531-540. Epub 2009 Jun 16. PMID: 19533544
Mederacke I, Wedemeyer H.
Nitazoxanide for the treatment of chronic hepatitis C New opportunities but new challenges?
Ann Hepatol. 2009 Apr 1;8(2):166-168. PMID: 19502665
Potthoff A, Witte T, Rifai K, Hoy L, Deterding K, Feyerabend S, Manns MP, Wedemeyer H.
Prevalence of alpha-fodrin antibodies in patients with chronic hepatitis C infection and Sjogren syndrome.
Scand J Gastroenterol. 2009;44(8):994-1003 PMID: 19462335
Erhardt A, Deterding K, Benhamou Y, Reiser M, Forns X, Pol S, Calleja JL, Ross S, Spangenberg HC, Garcia-Samaniego J, Fuchs M, Enríquez J, Wiegand J, Stern J, Wu K, Kukolj G, Marquis M, Beaulieu P, Nehmiz G, Steffgen J; BILB 1941 Study Group.
Safety, pharmacokinetics and antiviral effect of BILB 1941, a novel hepatitis C virus RNA polymerase inhibitor, after 5 days oral treatment.
Antivir Ther. 2009;14(1):23-32. PMID: 19320234
Klade CS, Kubitschke A, Stauber RE, Meyer MF, Zinke S, Wiegand J, Zauner W, Aslan N, Lehmann M, Cornberg M, Manns MP, Reisner P, Wedemeyer H.
Hepatitis C virus-specific T cell responses against conserved regions in recovered patients.
Vaccine. 2009 May 18;27(23):3099-108. Epub 2009 Mar 11. PMID: 19428924
Morice Y, Ratinier M, Miladi A, Chevaliez S, Germanidis G, Wedemeyer H, Laperche S, Lavergne JP, Pawlotsky JM.
Seroconversion to hepatitis C virus alternate reading frame protein during acute infection.
Hepatology. 2009 May;49(5):1449-59. PMID: 19350656
Jeffe F, Stegmann KA, Broelsch F, Manns MP, Cornberg M, Wedemeyer H.
Adenosine and IFN-{alpha} synergistically increase IFN-gamma production of human NK cells.
J Leukoc Biol. 2009 Mar;85(3):452-61. Epub 2008 Dec 26. PMID: 19095736
Mederacke I, Wedemeyer H, Manns MP.
Boceprevir, an NS3 serine protease inhibitor of hepatitis C virus, for the treatment of HCV infection.
Curr Opin Investig Drugs. 2009 Feb;10(2):181-9. PMID: 19197796
Ghosh A, Koestner W, Hapke M, Schlaphoff V, Langer F, Baumann R, Koenecke C, Cornberg M, Welte K, Blazar B, Sauer M.
Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft versus leukemia effects across MHC barriers in full chimeras.
Blood. 2009 Apr 30;113(18):4440-8. Epub 2009 Jan 30 PMID: 19182207
Suneetha PV, Schlaphoff V, Wang C, Stegmann KA, Fytili P, Sarin SK, Manns MP, Cornberg M, Wedemeyer H.
Effect of peptide pools on effector functions of antigen-specific CD8+ T cells.
J Immunol Methods. 2009 Mar 15;342(1-2):33-48. Epub 2009 Jan 9. PMID: 19135447
Wursthorn K, Manns MP, Wedemeyer H.
Natural history: the importance of viral load, liver damage and HCC.
Best Pract Res Clin Gastroenterol. 2008;22(6):1063-79. PMID: 19187867
Hadem J, Stiefel P, Bahr MJ, Wedemeyer H, Manns MP, Schneider AS.
Reply
Clin Gastroenterol Hepatol. 2008 Dec 31. PMID: 19121646
Moenkemeyer M, Schmidt RE, Wedemeyer H, Tillmann HL, Heiken H.
GBV-C coinfection is negatively correlated to Fas expression and Fas-mediated apoptosis in HIV-1 infected patients.
J Med Virol. 2008 Nov;80(11):1933-40. PMID: 18814245
Hadem J, Cornberg M, Hauptmann C, Süttmann U, Manns MP, Wedemeyer H.
Pneumococcal meningitis during antiviral treatment with interferon and ribavirin in a splenectomized patient with chronic hepatitis C - do not miss vaccination before starting therapy.
Z Gastroenterol. 2008 Sep;46(9):880-2. Epub 2008 Sep 22. PMID: 18810674
Deterding K, Manns MP, Wedemeyer H.
Does the presence of adefovir-resistant variants lead to failure of tenofovir monotherapy?
J Hepatol. 2008 Nov;49(5):862-3. Epub 2008 Aug 19. No abstract available. PMID: 18804309
Wiegand J, Deterding K, Cornberg M, Wedemeyer H.
Treatment of acute hepatitis C: the success of monotherapy with (pegylated) interferon alpha.
J Antimicrob Chemother. 2008 Nov;62(5):860-5. Epub 2008 Sep 5. PMID: 18776191
Ciesek S, Steinmann E, Manns MP, Wedemeyer H, Pietschmann T.
The suppressive effect that myriocin has on hepatitis C virus RNA replication is independent of inhibition of serine palmitoyl transferase.
J Infect Dis. 2008 Oct 1;198(7):1091-3. No abstract available. PMID: 18774886
Cornberg M, Protzer U, Dollinger MM, Petersen J, Wedemeyer H, Berg T, Jilg W, Erhardt A, Wirth S, Schirmacher P, Fleig WE, Manns MP; German Society for Digestive and Metabolic Diseases; German Society for Pathology; Society for Virology; Society for Pediatric Gastroenterology and Nutrition; Competence Network for Viral Hepatitis.
The German guideline for the management of hepatitis B virus infection: short version.
J Viral Hepat. 2008 Aug;15 Suppl 1:1-21. No abstract available. PMID: 18713127
Zeuzem S, Berg T, Moeller B, Hinrichsen H, Mauss S, Wedemeyer H, Sarrazin C, Hueppe D, Zehnter E, Manns MP.
Expert opinion on the treatment of patients with chronic hepatitis C.
J Viral Hepat. 2008 Aug 28. [Epub ahead of print] PMID: 18761607
Deterding K, Constantinescu I, Nedelcu FD, Gervain J, Nemecek V, Srtunecky O, Vince A, Grgurevic I, Bielawski KP, Zalewska M, Bock T, Ambrozaitis A, Stanczak J, Takács M, Chulanov V, Slusarczyk J, Drazd'áková M, Wiegand J, Cornberg M, Manns MP, Wedemeyer H.
Prevalence of HBV genotypes in Central and Eastern Europe.
J Med Virol. 2008 Oct;80(10):1707-11. PMID: 18712830
Lovric S, Erdbruegger U, Kümpers P, Woywodt A, Koenecke C, Wedemeyer H, Haller H, Haubitz M.
Rituximab as rescue therapy in anti-neutrophil cytoplasmic antibody-associated vasculitis: single centre experience with 15 patients.
Nephrol Dial Transplant. 2008 Aug 6. PMID: 18685144
Wiegand J, Wedemeyer H, Finger A, Heidrich B, Rosenau J, Michel G, Bock CT, Manns MP, Tillmann HL.
A decline in hepatitis B virus surface antigen (hbsag) predicts clearance, but does not correlate with quantitative hbeag or HBV DNA levels.
Antivir Ther. 2008;13(4):547-54. PMID: 18672533
Suneetha PV, Mederacke I, Heim A, Bastürk M, Cornberg M, Strassburg CP, Manns MP, Wedemeyer H.
Spontaneous clearance of chronic hepatitis C after liver transplantation: are hepatitis C virus-specific T cell responses the clue?
Liver Transpl. 2008 Aug;14(8):1225-7. PMID: 18668659
Fytili P, Dalekos GN, Schlaphoff V, Suneetha PV, Sarrazin C, Zauner W, Zachou K, Berg T, Manns MP, Klade CS, Cornberg M, Wedemeyer H.
Cross-genotype-reactivity of the immunodominant HCV CD8 T-cell epitope NS3-1073.
Vaccine. 2008 Jul 23;26(31):3818-26. PMID: 18582999
Veldt BJ, Chen W, Heathcote EJ, Wedemeyer H, Reichen J, Hofmann WP, de Knegt RJ, Zeuzem S, Manns MP, Hansen BE, Schalm SW, Janssen HL.
Increased risk of hepatocellular carcinoma among patients with hepatitis C cirrhosis and diabetes mellitus.
Hepatology. 2008 Jun;47(6):1856-62. PMID: 18506898
Girke J, Wedemeyer H, Wiegand J, Manns MP, Tillmann HL.
[Acute hepatitis B: is antiviral therapy indicated? Two case reports]
Dtsch Med Wochenschr. 2008 May;133(22):1178-82. German. PMID: 18491273
Potthoff A, Wedemeyer H, Boecher WO, Berg T, Zeuzem S, Arnold J, Spengler U, Gruengreiff K, Kaeser T, Schuchmann M, Bergk A, Forestier N, Deterding K, Manns MP, Trautwein C; for the Hep-Net B/C Co-infection Study Group.
The HEP-NET B/C co-infection trial: A prospective multicenter study to investigate the efficacy of pegylated interferon-alpha2b and ribavirin in patients with HBV/HCV co-infection.
J Hepatol. 2008 Apr 29. PMID: 18490077
Klade CS, Wedemeyer H, Berg T, Hinrichsen H, Cholewinska G, Zeuzem S, Blum H, Buschle M, Jelovcan S, Buerger V, Tauber E, Frisch J, Manns MP.
Therapeutic vaccination of chronic hepatitis C nonresponder patients with the peptide vaccine IC41.
Gastroenterology. 2008 May;134(5):1385-95. Epub 2008 Mar 4. PMID: 18471515
Kaiser T, Damerow HC, Tenckhoff S, Finger A, Böttcher I, Hafer C, Schwarz A, Lüth JB, Schmidt Gürtler H, Colucci G, Manns MP, Wedemeyer H, Tillmann HL.
Kinetics of hepatitis C viral RNA and HCV-antigen during dialysis sessions: evidence for differential viral load reduction on dialysis.
J Med Virol. 2008 Jul;80(7):1195-201. PMID: 18461613
Deterding K, Wiegand J, Grüner N, Wedemeyer H.
Medical procedures as a risk factor for HCV infection in developed countries: do we neglect a significant problem in medical care?
J Hepatol. 2008 Jun;48(6):1019-20; author reply 1020-1. PMID: 18439703
Mauss S, Wedemeyer H.
Treatment of chronic hepatitis B and the implications of viral resistance to therapy.
Expert Rev Anti Infect Ther. 2008 Apr;6(2):191-9. Review. PMID: 18380601
Hadem J, Stiefel P, Bahr MJ, Tillmann HL, Rifai K, Klempnauer J, Wedemeyer H, Manns MP, Schneider AS.
Prognostic implications of lactate, bilirubin, and etiology in German patients with acute liver failure.
Clin Gastroenterol Hepatol. 2008 Mar;6(3):339-45. PMID: 18328438
Ciesek S, Helfritz FA, Lehmann U, Becker T, Strassburg CP, Neipp M, Ciner A, Fytili P, Tillmann HL, Manns MP, Wedemeyer H.
Persistence of occult hepatitis B after removal of the hepatitis B virus-infected liver.
J Infect Dis. 2008 Feb 1;197(3):355-60. PMID: 18248299
Pischke S, Cornberg M, Manns MP.
[Hepatitis associated cryoglobulinemia.]
Internist (Berl). 2008 Mar;49(3):297-304. German. PMID: 18327517
Ciesek S, Liermann H, Hadem J, Greten T, Tillmann HL, Cornberg M, Aslan N, Manns MP, Wedemeyer H.
Impaired TRAIL-dependent cytotoxicity of CD1c-positive dendritic cells in chronic hepatitis C virus infection.
J Viral Hepat. 2008 Mar;15(3):200-11. PMID: 18233993
Wölk B, Wedemeyer H.
Hepatitis C virus living off the fat of the land.
Hepatology. 2008 Jan;47(1):343-5. PMID: 18161719
Deterding K, Pothakamuri SV, Schlaphoff V, Hadem J, Metzler F, Bahr MJ, Manns MP, Cornberg M, Wedemeyer H.
Clearance of Chronic HCV Infection During Acute Delta Hepatitis.
Infection. 2007 Dec 14. PMID: 18084714
Cornberg M, Protzer U, Dollinger MM, Petersen J, Wedemeyer H, Berg T, Jilg W, Erhardt A, Wirth S, Schirmacher P, Fleig WE, Manns MP.
Prophylaxis, diagnosis and therapy of hepatitis B virus (HBV) infection: the German guidelines for the management of HBV infection.
Z Gastroenterol. 2007 Dec;45(12):1281-328. PMID: 18080231
Steffen M, Cornberg M, Buggisch P.
Treatment of chronic hepatitis C with consensus interferon in relapsers and non-responders to interferon-based therapy.
Hepatogastroenterology. 2007 Dec;54(80):2368-72. Review. PMID: 18265667
Ciesek S, Manns MP, Wedemeyer H.
Viral hepatitis after liver transplantation. Which immunosuppressive drugs should be recommended?
Minerva Gastroenterol Dietol. 2007 Dec;53(4):337-50. Review. PMID: 18043552
Veldt BJ, Heathcote EJ, Wedemeyer H, Reichen J, Hofmann WP, Zeuzem S, Manns MP, Hansen BE, Schalm SW, Janssen HL.
Sustained virologic response and clinical outcomes in patients with chronic hepatitis C and advanced fibrosis.
Ann Intern Med. 2007 Nov 20;147(10):677-84. Summary for patients in: Ann Intern Med. 2007 Nov 20;147(10):I47. PMID: 18025443
Cooksley H, Chokshi S, Maayan Y, Wedemeyer H, Andreone P, Gilson R, Warnes T, Paganin S, Zoulim F, Frederick D, Neumann AU, Brosgart CL, Naoumov NV.
Hepatitis B virus e antigen loss during adefovir dipivoxil therapy is associated with enhanced virus-specific CD4+ T-cell reactivity.
Antimicrob Agents Chemother. 2008 Jan;52(1):312-20. PMID: 17984230
Potthoff A, Deterding K, Trautwein C, Rifai K, Manns MP, Wedemeyer H.
Sustained HCV-RNA response and hepatitis Bs seroconversion after individualized antiviral therapy with pegylated interferon alpha plus ribavirin and active vaccination in a hepatitis C virus/hepatitis B virus-coinfected patient.
Eur J Gastroenterol Hepatol. 2007 Oct;19(10):906-9. PMID: 17873617
Wedemeyer H, Cornberg M, Protzer U, Berg T, Dollinger MM.
[German guidelines on diagnosis and therapy of hepatitis B]
Dtsch Med Wochenschr. 2007 Aug;132(34-35):1775-82. Review. German. PMID: 17713890
Schlaphoff V, Klade CS, Jilma B, Jelovcan SB, Cornberg M, Tauber E, Manns MP, Wedemeyer H; IC41 Study Group.
Functional and phenotypic characterization of peptide-vaccine-induced HCV-specific CD8+ T cells in healthy individuals and chronic hepatitis C patients.
Vaccine. 2007 Sep 17;25(37-38):6793-806. Epub 2007 Jun 29. PMID: 17686555
Kubitschke A, Bader C, Tillmann HL, Manns MP, Kuhn S, Wedemeyer H.
[Injuries from needles contaminated with hepatitis C virus: how high is the risk of seroconversion for medical personnel really?]
Internist (Berl). 2007 Oct;48(10):1165-72. Review. German. PMID: 17684714
Fytili P, Tiemann C, Wang C, Schulz S, Schaffer S, Manns MP, Wedemeyer H.
Frequency of very low HCV viremia detected by a highly sensitive HCV-RNA assay.
J Clin Virol. 2007 Aug;39(4):308-11. Epub 2007 Jul 12. PMID: 17625963
Hadem J, Cornberg M, Länger F, Schedel I, Kirchhoff T, Niedermeyer J, Manns MP, Schöfl C.
Making sense of muscle fatigue and liver lesions.
Z Gastroenterol. 2007 Jul;45(7):609-11. PMID: 17620225
Wiegand J, Cornberg M, Aslan N, Schlaphoff V, Sarrazin C, Kubitschke A, Buggisch P, Ciner A, Jaeckel E, Manns MP, Wedemeyer H.
Fate and function of hepatitis-C-virus-specific T-cells during peginterferon-alpha2b therapy for acute hepatitis C.
Antivir Ther. 2007;12(3):303-16. PMID: 17591020
Meyer MF, Lehmann M, Cornberg M, Wiegand J, Manns MP, Klade C, Wedemeyer H.
Clearance of low levels of HCV viremia in the absence of a strong adaptive immune response.
Virol J. 2007 Jun 11;4:58. PMID: 17562015
Cornberg M, Protzer U, Dollinger MM, Petersen J, Wedemeyer H, Berg T, Jilg W, Erhardt A, Wirth S, Schirmacher P, Fleig WE, Manns MP.
[Prophylaxis, Diagnosis and Therapy of Hepatitis-B-Virus-(HBV-)Infection: upgrade of the guideline, AWMF-Register 021/011]
Z Gastroenterol. 2007 Jun;45(6):525-74. Epub 2007 Jun 6. German. PMID: 17554641
Wedemeyer H, Heidrich B, Manns MP.
Hepatitis D virus infection--not a vanishing disease in Europe!
Hepatology. 2007 May;45(5):1331-2; author reply 1332-3. PMID: 17464980
Rifai K, Wedemeyer H, Rosenau J, Klempnauer J, Strassburg CP, Manns MP, Tillmann HL.
Longer survival of liver transplant recipients with hepatitis virus coinfections.
Clin Transplant. 2007 Mar-Apr;21(2):258-64. PMID: 17425755
Lehmann U, Wingen LU, Brakensiek K, Wedemeyer H, Becker T, Heim A, Metzig K, Hasemeier B, Kreipe H, Flemming P.
Epigenetic defects of hepatocellular carcinoma are already found in non-neoplastic liver cells from patients with hereditary haemochromatosis.
Hum Mol Genet. 2007 Jun 1;16(11):1335-42. PMID: 17412760
Meyer MF, Wedemeyer H, Monazahian M, Dreesman J, Manns MP, Lehmann M.
Prevalence of hepatitis C in a German prison for young men in relation to country of birth.
Epidemiol Infect. 2007 Feb;135(2):274-80. PMID: 16824250
Potthoff A, Deterding K, Trautwein C, Flemming P, Strassburg CP, Manns MP, Wedemeyer H, Bahr MJ.
Steroid treatment for severe acute cryptogenic hepatitis.
Z Gastroenterol. 2007 Jan;45(1):15-9. PMID: 17236116
Kubitschke A, Bahr MJ, Aslan N, Bader C, Tillmann HL, Sarrazin C, Greten T, Wiegand J, Manns MP, Wedemeyer H.
Induction of hepatitis C virus (HCV)-specific T cells by needle stick injury in the absence of HCV-viraemia.
Eur J Clin Invest. 2007 Jan;37(1):54-64. PMID: 17181568
Trebst C, Wedemeyer H, Manns MP, Tillmann H, Windhagen A.
Treatment of hepatitis C virus-associated inflammatory polyneuropathy with pegylated interferon-alpha and ribavirin.
Eur J Gastroenterol Hepatol. 2007 Jan;19(1):91-2. PMID: 17206084
Cornberg M, Sheridan BS, Saccoccio FM, Brehm MA, Selin LK.
Protection against vaccinia virus challenge by CD8 memory T cells resolved by molecular mimicry.
J Virol. 2007 Jan;81(2):934-44. PMID: 17079318
Potthoff A, Tillmann HL, Bara C, Deterding K, Pethig K, Meyer S, Haverich A, Böker KH, Manns MP, Wedemeyer H.
Improved outcome of chronic hepatitis B after heart transplantation by long-term antiviral therapy.
J Viral Hepat. 2006 Nov;13(11):734-41. PMID: 17052272
Welsh RM, Kim SK, Cornberg M, Clute SC, Selin LK, Naumov YN.
The privacy of T cell memory to viruses.
Curr Top Microbiol Immunol. 2006;311:117-53. Review. PMID: 17048707
Deterding K, Tegtmeyer B, Cornberg M, Hadem J, Potthoff A, Böker KH, Tillmann HL, Manns MP, Wedemeyer H.
Hepatitis A virus infection suppresses hepatitis C virus replication and may lead to clearance of HCV.
J Hepatol. 2006 Dec;45(6):770-8. PMID: 17034895
Cornberg M, Deterding K, Manns MP.
Present and future therapy for hepatitis C virus.
Expert Rev Anti Infect Ther. 2006 Oct;4(5):781-93. Review. PMID: 17140355
Wedemeyer H, Cornberg M, Wiegand J, Manns M.
Treatment duration in acute hepatitis C: the issue is not solved yet.
Hepatology. 2006 Oct;44(4):1051; author reply 1051-2. PMID: 17006944
Rosenau J, Hooman N, Rifai K, Solga T, Tillmann HL, Grzegowski E, Nashan B, Klempnauer J, Strassburg CP, Wedemeyer H, Manns MP.
Hepatitis B virus immunization with an adjuvant containing vaccine after liver transplantation for hepatitis B-related disease: failure of humoral and cellular immune response.
Transpl Int. 2006 Oct;19(10):828-33. PMID: 16961775
Manns MP, Wedemeyer H, Cornberg M.
Treating viral hepatitis C: efficacy, side effects, and complications.
Gut. 2006 Sep;55(9):1350-9. Review. PMID: 16905701
Aslan N, Yurdaydin C, Wiegand J, Greten T, Ciner A, Meyer MF, Heiken H, Kuhlmann B, Kaiser T, Bozkaya H, Tillmann HL, Bozdayi AM, Manns MP, Wedemeyer H.
Cytotoxic CD4 T cells in viral hepatitis.
J Viral Hepat. 2006 Aug;13(8):505-14. PMID: 16901280
Wedemeyer H, Cornberg M, Wiegand J, Jäckel E, Manns MP.
Treatment of acute hepatitis C-how to explain the differences?
Gastroenterology. 2006 Aug;131(2):682-3; author reply 683-4. PMID: 16890627
Kronenberger B, Herrmann E, Hofmann WP, Wedemeyer H, Sester M, Mihm U, Ghaliai T, Zeuzem S, Sarrazin C.
Dynamics of CD81 expression on lymphocyte subsets during interferon-alpha-based antiviral treatment of patients with chronic hepatitis C.
J Leukoc Biol. 2006 Aug;80(2):298-308. PMID: 16735696
Selin LK, Brehm MA, Naumov YN, Cornberg M, Kim SK, Clute SC, Welsh RM.
Memory of mice and men: CD8+ T-cell cross-reactivity and heterologous immunity.
Immunol Rev. 2006 Jun;211:164-81. Review. PMID: 16824126
Volkmann X, Cornberg M, Wedemeyer H, Lehner F, Manns MP, Schulze-Osthoff K, Bantel H.
Caspase activation is required for antiviral treatment response in chronic hepatitis C virus infection.
Hepatology. 2006 Jun;43(6):1311-6. PMID: 16729308
Cornberg M, Chen AT, Wilkinson LA, Brehm MA, Kim SK, Calcagno C, Ghersi D, Puzone R, Celada F, Welsh RM, Selin LK.
Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity.
J Clin Invest. 2006 May;116(5):1443-56. Erratum in: J Clin Invest. 2007 May;117(5):1450. PMID: 16614754
Ormandy LA, Farber A, Cantz T, Petrykowska S, Wedemeyer H, Horning M, Lehner F, Manns MP, Korangy F, Greten TF.
Direct ex vivo analysis of dendritic cells in patients with hepatocellular carcinoma.
World J Gastroenterol. 2006 May 28;12(20):3275-82. PMID: 16718852
Tillmann HL, Hadem J, Leifeld L, Zachou K, Canbay A, Eisenbach C, Graziadei I, Encke J, Schmidt H, Vogel W, Schneider A, Spengler U, Gerken G, Dalekos GN, Wedemeyer H, Manns MP.
Safety and efficacy of lamivudine in patients with severe acute or fulminant hepatitis B, a multicenter experience.
J Viral Hepat. 2006 Apr;13(4):256-63. PMID: 16611192
Fytili P, Ciesek S, Manns MP, Wedemeyer H, Neipp M, Helfritz F, Klempnauer J, Bara C, Haverich A.
Anti-HBc seroconversion after transplantation of anti-HBc positive nonliver organs to anti-HBc negative recipients.
Transplantation. 2006 Mar 15;81(5):808-9. PMID: 16534488
Wiegand J, Buggisch P, Boecher W, Zeuzem S, Gelbmann CM, Berg T, Kauffmann W, Kallinowski B, Cornberg M, Jaeckel E, Wedemeyer H, Manns MP; German HEP-NET Acute HCV Study Group.
Early monotherapy with pegylated interferon alpha-2b for acute hepatitis C infection: the HEP-NET acute-HCV-II study.
Hepatology. 2006 Feb;43(2):250-6. PMID: 16440367
Meyer S, Manns MP, Wedemeyer H.
[Three years of vertical networking in the German Network of Competence on Viral Hepatitis: what can we learn from the usage of different information tools?]
Z Gastroenterol. 2006 Jan;44(1):15-23. German. PMID: 16397835
Cornberg M, Hadem J, Herrmann E, Schuppert F, Schmidt HH, Reiser M, Marschal O, Steffen M, Manns MP, Wedemeyer H.
Treatment with daily consensus interferon (CIFN) plus ribavirin in non-responder patients with chronic hepatitis C: a randomized open-label pilot study.
J Hepatol. 2006 Feb;44(2):291-301. PMID: 16360972
Clute SC, Watkin LB, Cornberg M, Naumov YN, Sullivan JL, Luzuriaga K, Welsh RM, Selin LK.
Cross-reactive influenza virus-specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosis.
J Clin Invest. 2005 Dec;115(12):3602-12. PMID: 16308574
Cornberg M, Manns MP.
New approaches and therapeutic modalities for the treatment of patients with chronic hepatitis C.
Ann Hepatol. 2005 Jul-Sep;4(3):144-50. Review. PMID: 16177653
Wedemeyer H, Manns MP.
Can epoetin alfa maintain ribavirin doses in patients with hepatitis C virus on combination therapy?
Nat Clin Pract Gastroenterol Hepatol. 2004 Nov;1(1):24-5. PMID: 16265040
Ciesek S, Ringe BP, Strassburg CP, Klempnauer J, Manns MP, Wedemeyer H, Becker T.
Effects of cyclosporine on human dendritic cell subsets.
Transplant Proc. 2005 Jan-Feb;37(1):20-4. PMID: 15808533
Potthoff A, Wiegand J, Lüth JB, Wedemeyer H, Manns MP, Tillmann HL.
Superiority of standard interferon-alpha2b compared to pegylated interferon-alpha2b (12 kDa) in a hemodialysis patient with chronic hepatitis C?
Clin Nephrol. 2005 Mar;63(3):232-5. PMID: 15786827
Ormandy LA, Hillemann T, Wedemeyer H, Manns MP, Greten TF, Korangy F.
Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma.
Cancer Res. 2005 Mar 15;65(6):2457-64. PMID: 15781662
Reiser M, Hinrichsen H, Benhamou Y, Reesink HW, Wedemeyer H, Avendano C, Riba N, Yong CL, Nehmiz G, Steinmann GG.
Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C.
Hepatology. 2005 Apr;41(4):832-5. PMID: 15732092
Kim SK, Cornberg M, Wang XZ, Chen HD, Selin LK, Welsh RM.
Private specificities of CD8 T cell responses control patterns of heterologous immunity.
J Exp Med. 2005 Feb 21;201(4):523-33. PMID: 15710651
Potthoff A, Sarhaddar J, Wiegand J, Lichtinghagen R, Sarrazin C, Ciner A, Hadem J, Trautwein C, Manns MP, Wedemeyer H.
Spontaneous resolution of chronic hepatitis C virus infection after antiviral treatment and relapse.
Hepatol Res. 2005 Jan;31(1):18-23. PMID: 15652466
Tillmann HL, Wiegand J, Glomb I, Jelineck A, Picchio G, Wedemeyer H, Manns MP.
Diagnostic algorithm for chronic hepatitis C virus infection: role of the new HCV-core antigen assay.
Z Gastroenterol. 2005 Jan;43(1):11-6. PMID: 15650966
Manns MP, Wedemeyer H.
Treatment of hepatitis C in HIV-infected patients: significant progress but not the final step.
JAMA. 2004 Dec 15;292(23):2909-13. PMID: 15598923
Ritter M, Ali MY, Grimm CF, Weth R, Mohr L, Bocher WO, Endrulat K, Wedemeyer H, Blum HE, Geissler M.
Immunoregulation of dendritic and T cells by alpha-fetoprotein in patients with hepatocellular carcinoma.
J Hepatol. 2004 Dec;41(6):999-1007. PMID: 15582134
Hinrichsen H, Benhamou Y, Wedemeyer H, Reiser M, Sentjens RE, Calleja JL, Forns X, Erhardt A, Crönlein J, Chaves RL, Yong CL, Nehmiz G, Steinmann GG.
Short-term antiviral efficacy of BILN 2061, a hepatitis C virus serine protease inhibitor, in hepatitis C genotype 1 patients.
Gastroenterology. 2004 Nov;127(5):1347-55. PMID: 15521004
Selin LK, Cornberg M, Brehm MA, Kim SK, Calcagno C, Ghersi D, Puzone R, Celada F, Welsh RM.
CD8 memory T cells: cross-reactivity and heterologous immunity.
Semin Immunol. 2004 Oct;16(5):335-47. Review. PMID: 15528078
Martin JH, Potthoff A, Ledig S, Cornberg M, Jandl O, Manns MP, Kubicka S, Flemming P, Athmann C, Beil W, Wagner S.
Effect of H. pylori on the expression of TRAIL, FasL and their receptor subtypes in human gastric epithelial cells and their role in apoptosis.
Helicobacter. 2004 Oct;9(5):371-86. PMID: 15361075
Manns MP, Caselmann WH, Wiedmann KH, Wedemeyer H.
[Standard treatment of chronic hepatitis B]
Z Gastroenterol. 2004 Aug;42(8):687-91. Review. German. PMID: 15314716
Manns MP, Wedemeyer H, Meyer S, Roggendorf M, Niederau C, Blum HE, Jilg W, Fleig WE; German Society for Alimentary Metabolic Disorders; Hepatitis Competence Network.
[Diagnosis, progression and therapy of hepatitis-B-virus infection--results of an evidenced based consensus conference of the German Society for Alimentary Metabolic Disorders and and in cooperation with the Hepatitis Competence Network]
Z Gastroenterol. 2004 Aug;42(8):677-8. Review. German. PMID: 15314713
Seifert U, Liermann H, Racanelli V, Halenius A, Wiese M, Wedemeyer H, Ruppert T, Rispeter K, Henklein P, Sijts A, Hengel H, Kloetzel PM, Rehermann B.
Hepatitis C virus mutation affects proteasomal epitope processing.
J Clin Invest. 2004 Jul;114(2):250-9. PMID: 15254592
Wiegand J, Jäckel E, Cornberg M, Hinrichsen H, Dietrich M, Kroeger J, Fritsch WP, Kubitschke A, Aslan N, Tillmann HL, Manns MP, Wedemeyer H.
Long-term follow-up after successful interferon therapy of acute hepatitis C.
Hepatology. 2004 Jul;40(1):98-107. PMID: 15239091
Lehmann M, Meyer MF, Monazahian M, Tillmann HL, Manns MP, Wedemeyer H.
High rate of spontaneous clearance of acute hepatitis C virus genotype 3 infection.
J Med Virol. 2004 Jul;73(3):387-91. PMID: 15170633
Wedemeyer H, Jäckel E, Wiegand J, Cornberg M, Manns MP.
Whom? When? How? Another piece of evidence for early treatment of acute hepatitis C.
Hepatology. 2004 May;39(5):1201-3. Review. PMID: 15122747
Hadem J, Wedemeyer H, Manns MP.
[Hepatitis as a travel disease]
Internist (Berl). 2004 Jun;45(6):655-68. Review. German. PMID: 15118829
Selin LK, Cornberg M.
Embedding T cells in the matrix.
Nat Med. 2004 Apr;10(4):343-5. PMID: 15057225
Jaeckel E, Wedemeyer H, Wiegand J, Manns MP.
Acute hepatitis C virus infection: to treat or not to treat?
Gastroenterology. 2004 Apr;126(4):1219-20; author reply 1220. PMID: 15057772
Wedemeyer H, Meyer S, Manns MP.
[Hepatitis (Hep-Net) competence network]
Internist (Berl). 2004 Apr;45(4):415-21. German. PMID: 14999382
Manns MP, Hadem J, Wedemeyer H.
Hepatitis B virus: where are we and where are we going?
Methods Mol Med. 2004;96:415-43. Review. PMID: 14762285
Tillmann HL, Wedemeyer H, Manns MP.
Treatment of hepatitis B in special patient groups: hemodialysis, heart and renal transplant, fulminant hepatitis, hepatitis B virus reactivation.
J Hepatol. 2003;39 Suppl 1:S206-11. Review. PMID: 14708705
Wedemeyer H, Cornberg M, Tegtmeyer B, Frank H, Tillmann HL, Manns MP.
Isolated anti-HBV core phenotype in anti-HCV-positive patients is associated with hepatitis C virus replication.
Clin Microbiol Infect. 2004 Jan;10(1):70-2. PMID: 14706089
Manns MP, Meyer S, Wedemeyer H.
The German network of excellence for viral hepatitis (Hep-Net).
Hepatology. 2003 Sep;38(3):543-4. PMID: 12939578
Wedemeyer H, Kuipers JG, Streetz K, Mengel M, Schedel I, Kezmic N, Meier P, Zeidler H, Manns MP, Wagner S.
A rare manifestation of Behçet's syndrome: immunological correlates and successful treatment of an esophageal ulcer.
Dig Dis Sci. 2003 Jul;48(7):1385-91. PMID: 12870801
Klein C, Bock CT, Wedemeyer H, Wüstefeld T, Locarnini S, Dienes HP, Kubicka S, Manns MP, Trautwein C.
Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA.
Gastroenterology. 2003 Jul;125(1):9-18. PMID: 12851866
Cornberg M, Hüppe D, Wiegand J, Felten G, Wedemeyer H, Manns MP.
[Treatment of chronic hepatitis C with PEG-interferon alpha-2b and ribavirin: 24 weeks of therapy are sufficient for HCV genotype 2 and 3]
Z Gastroenterol. 2003 Jun;41(6):517-22. German. PMID: 12806536
Wedemeyer H.
[Virus hepatitis: prevalence disease with many manifestations]
Pflege Z. 2003 Feb;56(2):90-4. German. PMID: 12673861
Streetz KL, Buhr T, Wedemeyer H, Bleck J, Schedel I, Manns MP, Göke MN.
Acute CMV-colitis in a patient with a history of ulcerative colitis.
Scand J Gastroenterol. 2003 Jan;38(1):119-22. PMID: 12608474
Wedemeyer H, Manns MP.
[Acute hepatitis C--therapy with interferon alpha-2b]
Internist (Berl). 2002 Nov;43(11):1477-8. German. PMID: 12524927
Vogel A, Wedemeyer H, Manns MP, Strassburg CP.
Autoimmune hepatitis and overlap syndromes.
J Gastroenterol Hepatol. 2002 Dec;17 Suppl 3:S389-98. Review. PMID: 12472969
Potthoff A, Ledig S, Martin J, Jandl O, Cornberg M, Obst B, Beil W, Manns MP, Wagner S.
Significance of the caspase family in Helicobacter pylori induced gastric epithelial apoptosis.
Helicobacter. 2002 Dec;7(6):367-77. PMID: 12485124
Wedemeyer H, Wiegand J, Cornberg M, Manns MP.
Polyethylene glycol-interferon: current status in hepatitis C virus therapy.
J Gastroenterol Hepatol. 2002 Dec;17 Suppl 3:S344-50. Review. PMID: 12472962
Greten TF, Korangy F, Neumann G, Wedemeyer H, Schlote K, Heller A, Scheffer S, Pardoll DM, Garbe AI, Schneck JP, Manns MP.
Peptide-beta2-microglobulin-MHC fusion molecules bind antigen-specific T cells and can be used for multivalent MHC-Ig complexes.
J Immunol Methods. 2002 Dec 20;271(1-2):125-35. PMID: 12445736
Wedemeyer H, He XS, Nascimbeni M, Davis AR, Greenberg HB, Hoofnagle JH, Liang TJ, Alter H, Rehermann B.
Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection.
J Immunol. 2002 Sep 15;169(6):3447-58. PMID: 12218168
Cornberg M, Hinrichsen H, Teuber G, Berg T, Naumann U, Falkenberg C, Zeuzem S, Manns MP.
Mycophenolate mofetil in combination with recombinant interferon alfa-2a in interferon-nonresponder patients with chronic hepatitis C.
J Hepatol. 2002 Dec;37(6):843-7. PMID: 12445427
Makkink MK, Schwerbrock NM, Mähler M, Boshuizen JA, Renes IB, Cornberg M, Hedrich HJ, Einerhand AW, Büller HA, Wagner S, Enss ML, Dekker J.
Fate of goblet cells in experimental colitis.
Dig Dis Sci. 2002 Oct;47(10):2286-97. PMID: 12395902
Cornberg M, Wedemeyer H, Manns MP.
Hepatitis C: therapeutic perspectives.
Forum (Genova). 2001 Apr-Jun;11(2):154-62. Review. PMID: 11948360
Cornberg M, Wedemeyer H, Manns MP.
Treatment of chronic hepatitis C with PEGylated interferon and ribavirin.
Curr Gastroenterol Rep. 2002 Feb;4(1):23-30. Review PMID: 11825538
Jaeckel E, Cornberg M, Wedemeyer H, Santantonio T, Mayer J, Zankel M, Pastore G, Dietrich M, Trautwein C, Manns MP; German Acute Hepatitis C Therapy Group.
Treatment of acute hepatitis C with interferon alfa-2b.
N Engl J Med. 2001 Nov 15;345(20):1452-7. PMID: 11794193
Satoi J, Murata K, Lechmann M, Manickan E, Zhang Z, Wedemeyer H, Rehermann B, Liang TJ.
Genetic immunization of wild-type and hepatitis C virus transgenic mice reveals a hierarchy of cellular immune response and tolerance induction against hepatitis C virus structural proteins.
J Virol. 2001 Dec;75(24):12121-7. PMID: 11711603
Wedemeyer H, Mizukoshi E, Davis AR, Bennink JR, Rehermann B.
Cross-reactivity between hepatitis C virus and Influenza A virus determinant-specific cytotoxic T cells.
J Virol. 2001 Dec;75(23):11392-400. PMID: 11689620
Wedemeyer H, Gagneten S, Davis A, Bartenschlager R, Feinstone S, Rehermann B.
Oral immunization with HCV-NS3-transformed Salmonella: induction of HCV-specific CTL in a transgenic mouse model.
Gastroenterology. 2001 Nov;121(5):1158-66. PMID: 11677208
Wedemeyer H, Cornberg M, Manns MP.
[PEG-interferons: significance for the treatment of viral hepatitis B and C]
Dtsch Med Wochenschr. 2001 Jun 1;126 Suppl 1:S68-75. Review. German. PMID: 11450618
Cornberg M, Enss ML, Wagner S.
[Differential mucin expression in the gastrointestinal tract]
Z Gastroenterol. 2001 May;39(5):369-76, 378. Review. German.PMID: 11413917
Widjaja A, Wedemeyer H, Tillmann HL, Horn R, Ockenga J, Jaeckel E, von zur Mühlen A, Manns MP, Brabant G.
Hepatitis C and the leptin system: bound leptin levels are elevated in patients with hepatitis C and decrease during antiviral therapy.
Scand J Gastroenterol. 2001 Apr;36(4):426-31. PMID: 11336170
Manns MP, Cornberg M, Wedemeyer H.
Current and future treatment of hepatitis C.
Indian J Gastroenterol. 2001 Mar;20 Suppl 1:C47-51. Review. PMID: 11293180
Wedemeyer H, Pethig K, Manns MP, Böker KH.
Hepatitis B infection in heart transplant patients.
Gastroenterology. 2001 Apr;120(5):1311-3. PMID: 11288750
Wesche B, Jaeckel E, Trautwein C, Wedemeyer H, Falorni A, Frank H, von zur Mühlen A, Manns MP, Brabant G.
Induction of autoantibodies to the adrenal cortex and pancreatic islet cells by interferon alpha therapy for chronic hepatitis C.
Gut. 2001 Mar;48(3):378-83. PMID: 11171829
Mix H, Widjaja A, Jandl O, Cornberg M, Kaul A, Göke M, Beil W, Kuske M, Brabant G, Manns MP, Wagner S.
Expression of leptin and leptin receptor isoforms in the human stomach.
Gut. 2000 Oct;47(4):481-6. PMID: 10986207
Enss ML, Cornberg M, Wagner S, Gebert A, Henrichs M, Eisenblätter R, Beil W, Kownatzki R, Hedrich HJ.
Proinflammatory cytokines trigger MUC gene expression and mucin release in the intestinal cancer cell line LS180.
Inflamm Res. 2000 Apr;49(4):162-9. PMID: 10858016
Cornberg M, Enss ML, Makkink MK, Beil W, Bock CT, Sobek-Klocke I, Mix H, Hiller W, Manns MP, Wagner S.
Variation of human mucin gene expression in gastric cancer cell lines and gastric mucous cell primary cultures.
Eur J Cell Biol. 1999 Nov;78(11):832-41. PMID: 10604660
Wedemeyer H, Böker KH, Pethig K, Petzold DR, Flemming P, Tillmann HL, Vollmar J, Bastürk M, Goldmann E, Griffin KE, Haverich A, Manns MP.
Famciclovir treatment of chronic hepatitis B in heart transplant recipients: a prospective trial.
Transplantation. 1999 Nov 27;68(10):1503-11. PMID: 10589947
He XS, Rehermann B, López-Labrador FX, Boisvert J, Cheung R, Mumm J, Wedemeyer H, Berenguer M, Wright TL, Davis MM, Greenberg HB.
Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers.
Proc Natl Acad Sci U S A. 1999 May 11;96(10):5692-7. PMID: 10318946
Dalekos GN, Wedemeyer H, Obermayer-Straub P, Kayser A, Barut A, Frank H, Manns MP.
Epitope mapping of cytochrome P4502D6 autoantigen in patients with chronic hepatitis C during alpha-interferon treatment.
J Hepatol. 1999 Mar;30(3):366-75. PMID: 10190716
Schöfl C, Ponczek M, Mader T, Waring M, Benecke H, von zur Mühlen A, Mix H, Cornberg M, Böker KH, Manns MP, Wagner S.
Regulation of cytosolic free calcium concentration by extracellular nucleotides in human hepatocytes.
Am J Physiol. 1999 Jan;276(1 Pt 1):G164-72. PMID: 9886992
Wedemeyer H, Caselmann WH, Manns MP.
Combination therapy of chronic hepatitis C: an important step but not the final goal!
J Hepatol. 1998 Dec;29(6):1010-4. No abstract available. PMID: 9875652
Wedemeyer H, Pethig K, Wagner D, Flemming P, Oppelt P, Petzold DR, Haverich A, Manns MP, Boeker KH.
Long-term outcome of chronic hepatitis B in heart transplant recipients.
Transplantation. 1998 Nov 27;66(10):1347-53. PMID: 9846521
Wagner S, Enss ML, Cornberg M, Mix H, Schumann S, Kirchner G, Jähne J, Manns MP, Beil W.
Morphological and molecular characterization of human gastric mucous cells in long-term primary culture.
Pflugers Arch. 1998 Nov;436(6):871-81. PMID: 9799401
Wedemeyer H, Jäckel E, Wedemeyer J, Frank H, Schüler A, Trautwein C, Manns MP.
[Is combination therapy of chronic hepatitis C with interferon alpha and ribavirin in primary interferon nonresponders indicated?--An analysis of personal experiences and review of the literature]
Z Gastroenterol. 1998 Sep;36(9):819-27. Review. German. PMID: 9795411
Wedemeyer H, Ockenga J, Frank H, Tillmann HL, Schuler A, Caselitz M, Gebel M, Trautwein C, Manns MP.
Perihepatic lymphadenopathy: a marker of response to interferon alpha in chronic hepatitis C.
Hepatogastroenterology. 1998 Jul-Aug;45(22):1062-8. PMID: 9756007
Rambusch EG, Wedemeyer H, Tillmann HL, Heringlake S, Manns MP.
[Significance of coinfection with hepatitis G virus for chronic hepatitis C--a review of the literature]
Z Gastroenterol. 1998 Jan;36(1):41-53. Review. German. PMID: 9531689