2009
Dreger SC, Schulz F, Huelsenbeck J, Gerhard R, Hofmann F, Just I, Genth H.
Killing of Rat Basophilic Leukemia Cells by Lethal Toxin from Clostridium sordellii: Critical Role of Phosphatidylinositide 3'-OH Kinase/Akt Signaling
Biochemistry 2009;6
Andresen H, Bingel U, Streichert T, Schmoldt A, Zörner A, Tsikas D, Just I.
Severe glycerol intoxication after Menière's disease diagnostic - case report and overview of kinetic data.
Clinical Toxicology 2009;47;312-316
Nerlich A, Rohde M, Talay SR, Genth H, Just I, Chhatwal GS.
Invasion of Endothelial Cells by Tissue-invasive M3 Type Group A Streptococci Requires Src Kinase and Activation of Rac1 by a Phosphatidylinositol 3-Kinase-independent Mechanism.
J Biol Chem 2009;284(30);20319-20328
Sun X, He X, Tzipori S, Gerhard R, Feng H.
Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-α by macrophages.
Microbial Pathogenesis 2009;46;298-305
Schoentaube J, Olling A, Tatge H, Just I, Gerhard R.
Serine-71-phosphorylation of Rac1/Cdc42 diminshes the pathogenic effect of Clostridium difficile toxin A.
Cell Microbiol 2009;11(12);1816-1826
Schulz F, Just I, Genth H.
Prevention of Clostridium sordellii Lethal Toxininduced apoptotic cell death by Tauroursodeoxycholic Acid.
Biochemistry 2009;48(38),9002-9010
Deplazes J, Fuchs M, Rauser S, Genth H, Lengyel E, Luber B.
Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.
Hum Mol Genet 2009;18(19);3632-3644
Hülsenbeck SC, May M, Schmidt G, Genth H.
Inhibition of cytokinesis by Clostridium difficile toxin B and cytotoxic necrotizing factors-reinforcing the critical role of RhoA in cytokinesis.
Cell Motil Cytoskeleton 2009;66(11);967-975
Lange O, Bigalke H, Dengler R, Wegner F, deGroot M, Wohlfarth K.
Neutralilzing antibodies and secondara therapy failure after treatment with botulinum toxin type A: much ado about nothing?
Clin Neurophamacol 2009;32(4);213-218
Rummel A, Häfner K, Mahrhold S, Darashchonak N, Holt M, Jahn R, Beerman S, Karnath T, Bigalke H, Binz T.
Botulinum neurotoxins C, E and F bind gangliosides vis a conserverd binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoformes of SV2 als second rezeptor.
J Neurochem 2009;110(6);1942-1954
Mohammadi B, Buhr N, Bigalke H, Krampfl K, Dengler R, Kollewe K.
A long-term follow-up of botulinum toxin A in cervical dystonia.
Neurol Res 2009;32(5);463-466
Mohammadi B, Kollewe K, Wegener M, Bigalke H, Dengler R.
Experience with long-term treatment with albumin-supplement botulinum toxin type A.
J Neural Transm 2009;116(4);437-441
Lange O, Bigalke H, Dengler R, Wegner F, deGroot M, Wohlfarth K.
Neutralizing antibodies and secondary therapy failure after treatment with botulinum toxin type A: much ado about nothing?
Clin Neuropharmacol 2009;32(4);213-218
Kotz A, Wagner J, Engel J, Routier F, Echternacher B; Pich A, Rhode M, Hoffmann P, Heesemann J, Ebel F.
The mitA gene of Aspergillus fumigatus ist required for mannosylation of inositol-phosphorylceramide, but is dispensable for pathogenicity.
Fungal Genet Biol 2009;47(2);169-178
Hülsenbeck SC, Klose I, Reichenbach M, Hülsenbeck J, Genth H.
Distinct kinetics of (H/K/N)Ras gluscoylation and Rac1 glucosylation catalysed by Clostridium sordellii toxin.
FEBS Lett 2009;593(19);3133-3139
Binz T, Rummel A.
Cell entry strategy of clostridial neurotoxins.
J Neurochem 2009;109(6);1584-1595
von Witzendorff, Maass K, Pich A, Ebeling S, Kölle S, Kochel C.
Characterization of the acidic N-linked glycans of the zona pellucida of prepuberal pigs by a mass spectrometric approach.
Carbohydr Res 2009;344(129;1541-1549
Brunger AT, Rummel A.
Receptor and substrate interations of clostridial neurotoxins.
Toxicon 2009;54(5);550-560
Genth H, Schulz F, Just I.
Glucosylation of Rho/Ras Proteins by Lethal Toxin - Implications of Actin-Re-Organization and Apoptosis in C. Sordellii-Associated Disease.
The Open Toxinology Journal 2009;2
Just I, Hülsenbeck SC, Genth H.
Clostridium Botulinum C3 Exoenzyme: Rho-Inactivating Tool in Cell Biology and an Neurothrophic Agent.
The Open Toxinology Journal 2009;2